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1. 发明公开

EP0429304A3 Pyridone-carboxylic acid derivatives and their use as veterinary medicines 失效
标题翻译：吡咯烷酮羧酸衍生物及其作为兽药的用途
公开(公告)号：EP0429304A3
公开(公告)日：1991-08-14
申请号：EP90312692.8
申请日：1990-11-21
申请人： SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD.
发明人： Imose, Jun , Kataoka, Takahiro , Hidaka, Shigetada , Ueda, Kazuo , Ogata, Masaru , Takahashi, Toshio
IPC分类号： C07D401/04 , C07D471/04 , C07D498/06
CPC分类号： C07D401/04 , C07D471/04
摘要： A veterinary composition for the treatment or prophylaxis of infectious diseases caused by infectious microorganisms which comprises at least one pyridone-carboxylic acid compound of the formula:
wherein
R¹ is lower alkyl, halo(lower)alkyl, cyclo(lower) alkyl or substituted or unsustituted phenyl;
R² and R³ are each hydrogen, hydroxyl, lower alkoxy, halogen or a group of the formula: -CH₂N(R⁵)R⁶ (in which R⁵ and R⁶ are each hydrogen, lower alkyl, lower alkenyl or hydroxy(lower)alkyl);
R⁴ is hydrogen, oxo, hydroxyl, lower alkoxy, halogen or a group of the formula: -CH₂N(R⁷)R⁸ (in which R⁷ and R⁸ are each hydrogen or lower alkyl;
X is hydrogen or halogen;
Y is CQ (in which Q is hydrogen or halogen) or nitrogen or, when taken together with R¹, may form a group of the formula: =C-OCH₂C(R⁹)H- (in which R⁹ is hydrogen or lower alkyl and the carbon atom to which R⁹ is attached links to the nitrogen atom in the pyridone ring); the compound themselves and a process for their production.

2. 发明公开

EP0429304A2 Pyridone-carboxylic acid derivatives and their use as veterinary medicines 失效
标题翻译： Pyridon-Carbonsäurederivateund ihre Verwendung als Tierarzneimittel。
公开(公告)号：EP0429304A2
公开(公告)日：1991-05-29
申请号：EP90312692.8
申请日：1990-11-21
申请人： SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD.
发明人： Imose, Jun , Kataoka, Takahiro , Hidaka, Shigetada , Ueda, Kazuo , Ogata, Masaru , Takahashi, Toshio
IPC分类号： C07D401/04 , C07D471/04 , C07D498/06
CPC分类号： C07D401/04 , C07D471/04
摘要： A veterinary composition for the treatment or prophylaxis of infectious diseases caused by infectious microorganisms which comprises at least one pyridone-carboxylic acid compound of the formula:
wherein
R¹ is lower alkyl, halo(lower)alkyl, cyclo(lower) alkyl or substituted or unsustituted phenyl;
R² and R³ are each hydrogen, hydroxyl, lower alkoxy, halogen or a group of the formula: -CH₂N(R⁵)R⁶ (in which R⁵ and R⁶ are each hydrogen, lower alkyl, lower alkenyl or hydroxy(lower)alkyl);
R⁴ is hydrogen, oxo, hydroxyl, lower alkoxy, halogen or a group of the formula: -CH₂N(R⁷)R⁸ (in which R⁷ and R⁸ are each hydrogen or lower alkyl;
X is hydrogen or halogen;
Y is CQ (in which Q is hydrogen or halogen) or nitrogen or, when taken together with R¹, may form a group of the formula: =C-OCH₂C(R⁹)H- (in which R⁹ is hydrogen or lower alkyl and the carbon atom to which R⁹ is attached links to the nitrogen atom in the pyridone ring); the compound themselves and a process for their production.
摘要翻译：用于治疗或预防由感染性微生物引起的感染性疾病的兽用组合物，其包含至少一种下式的吡啶酮羧酸化合物：其中R 1为低级烷基，卤代（低级）烷基，环（低级））烷基或取代或未取代的苯基; R 2和R 3各自为氢，羟基，低级烷氧基，卤素或下式基团：-CH 2 N（R 5）R 6（其中R 5和R 6）各自为氢，低级烷基，低级烯基或羟基（低级）烷基）; R 4是氢，氧代，羟基，低级烷氧基，卤素或下式的基团：-CH 2 N（R 7）R 8（其中R 7和R 8各自是氢或低级烷基; X是氢或卤素; Y是CQ（其中Q是氢或卤素）或氮，或者当与R 1一起时可以形成下式的基团：= C-OCH 2 C（R 9） >）H-（其中R 9是氢或低级烷基，R 9连接的碳原子连接到吡啶酮环中的氮原子）;化合物本身及其制备方法。

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