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1. 发明公开

EP1796896A1 PAD PRINTING METHOD FOR MAKING COLORED CONTACT LENSES 有权转让
标题翻译：移印工艺用于生产有色镜片
公开(公告)号：EP1796896A1
公开(公告)日：2007-06-20
申请号：EP05788447.0
申请日：2005-09-29
申请人： Novartis AG , NOVARTIS-PHARMA GMBH
发明人： TUCKER, Robert, Carey , CORTI, Sandra , QUINN, Michael, Hugh , ATKINS, Barry, L.
IPC分类号： B29D11/00 , G02C7/04 , C09D11/10 , B29C37/00
CPC分类号： C09D11/101 , B41F17/001
摘要： The invention provides a method for producing colored contact lenses with relatively high quality color images. The method of the invention comprises the steps of: (a) obtaining a water-based ink, the ink having a viscosity of greater than (100) centipoise (cps), and the ink comprising water, at least one colorant, a water-soluble binder polymer having ethylenically unsaturated groups, an initiator, and a surfactant, wherein the surfactant is present in the ink in an amount sufficient to provide the ink a dynamic surface tension of less than 40 mN/m at surface age of 1 second; (b) applying the ink, by using pad transfer printing technique, to at least a portion of at least one of molding surfaces of a lens mold to form a colored coat; (c) actinically or thermally curing the ink printed on the mold to form a colored film, wherein the printed ink is cured to an extent so that no noticeable color smearing is observed by examination with naked eyes; (d) dispensing a lens-forming material into the lens-forming cavity of the mold; and (e) actinically or thermally curing the lens-forming material within the lens-forming cavity to form a colored contact lens, whereby the colored film detaches from the molding surface and becomes integral with the body of the contact lens, wherein the colored film becomes part of one of the anterior and posterior surface of the colored contact lens and has a good adhesion to the lens.

2. 发明公开

EP1797474A1 PAD TRANSFER PRINTING METHOD FOR MAKING COLORED CONTACT LENSES 有权转让
标题翻译： PAD转移印花工艺用于生产有色镜片
公开(公告)号：EP1797474A1
公开(公告)日：2007-06-20
申请号：EP05794443.1
申请日：2005-09-29
申请人： Novartis AG , NOVARTIS-PHARMA GMBH
发明人： ATKINS, Barry, L. , DOERR, Norbert , FISCHER, Alfred , QUINN, Michael, Hugh , SCHMIEDER, Roland , TUCKER, Robert, Carey
IPC分类号： G02C7/04 , B29D11/00 , D06P5/00 , B05C17/02 , G02B1/04
CPC分类号： B29D11/00865 , B29D11/00903 , D06P5/003 , D06P5/007 , D06P5/2005 , G02B1/043
摘要： The invention provides a method for producing colored contact lenses with high quality color images. The method of the invention comprises the steps of (a) providing a water based ink in at least one cliché wherein a pattern to be printed on the contact lens has been created; (b) transferring the water based ink from the cliché to at least one surface of at least one contact lens forming mold by means of at least one transfer pad; (c) at least partially curing the ink transferred on the mold to form a colored film; (d) dispensing a hydrogel lens-forming material into the mold; and (e) curing the lens-forming material within the mold to form the contact lens, whereby the colored film detaches from the molding surface and becomes integral with the body of the contact lens; characterized in that the relative air humidity in the immediate vicinities of the transfer pad/s is kept higher than 50% at standard pressure and temperature conditions during ink transfer.

3. 发明公开

EP1763547A1 SILICONE HYDROGELS WITH LATHABILITY AT ROOM TEMPERATURE 有权
标题翻译：在室温下LANZETTIERBARE硅水凝胶
公开(公告)号：EP1763547A1
公开(公告)日：2007-03-21
申请号：EP05770095.7
申请日：2005-06-29
申请人： Novartis AG , NOVARTIS-PHARMA GMBH
发明人： PHELAN, John, Christopher , QUINN, Michael, Hugh , DOMSCHKE, Angelika, Maria
IPC分类号： C08F287/00 , G02B1/04
CPC分类号： C08F290/068 , C08F230/08 , G02B1/043 , C08L51/085
摘要： The present invention provides silicone hydrogel materials which can be lathed at room temperature and have a high oxygen permeability and a water content of from about 18% to 55% by weight. In addition, the invention provides contact lenses comprising a silicone hydrogel material of the invention.

4. 发明公开

EP1570011A1 BIOCOMPATIBLE INKS AND CONTACT LENSES COLOURED WITH SAID INKS 审中-公开
标题翻译：生物相容性油墨和任何有色镜片
公开(公告)号：EP1570011A1
公开(公告)日：2005-09-07
申请号：EP03809755.6
申请日：2003-10-31
申请人： Novartis AG , Novartis Pharma GmbH
发明人： PHELAN, John, Christopher , QUINN, Michael, Hugh
IPC分类号： C09D11/10 , C09D11/14 , G02C7/04 , B29D11/00 , C09D201/00
CPC分类号： C09D11/36 , C09D11/101 , G02B1/043
摘要： An aqueous ink comprising containing a colorant and a radiation-curable oligomer or polymer containing H-active groups bonded to the oligomer or polymer backbone, some or all of whose hydrogen atoms have been substituted by radicals of a N-hydroxyalkyl (meth)acrylamide. Methods for printing the inventive inks upon medical devices, such as contact lenses, are also disclosed.

5. 发明公开

EP1735643A1 COLORED INK FOR PAD TRANSFER PRINTING OF SILICONE HYDROGEL LENSES 有权转让
标题翻译：彩色油墨，有机硅水凝胶镜片垫转移印花
公开(公告)号：EP1735643A1
公开(公告)日：2006-12-27
申请号：EP05731571.5
申请日：2005-03-31
申请人： Novartis AG , Novartis Pharma GmbH
发明人： QUINN, Michael, Hugh , CARLSON, Gregory, Glen , ATKINS, Barry, L.
IPC分类号： G02B1/04 , C09D11/10 , C09D11/00 , B29D11/00 , G02C7/04
CPC分类号： G02B1/10 , B29C41/003 , B29D11/00048 , B29D11/00317 , B29K2083/005 , B29K2105/0014 , B29K2105/0032 , B29K2105/0061 , B29L2009/00 , B29L2011/0041 , C09D11/107 , G02B1/043 , C08L83/04
摘要： The present invention provides a method for making colored silicone hydrogel contact lenses. The method of the invention comprises the steps of: (a) applying a color coat to at least a portion of at least one of molding surfaces of a lens mold with an ink, wherein the ink comprises at least one colorant, a binder polymer, an adhesion promoter, and optionally a diluent, wherein the binder polymer is a copolymerization product of a polymerizable mixture including (i) at least one hydrophilic vinylic monomer; (ii) at least one functionalizing vinylic monomer containing at least one functional group selected from the group consisting of hydroxyl group -OH, amino group -NHR (wherein R is hydrogen or C 1 to C 8 alkyl), carboxylic group -COOH, epoxy group, amide group -CONHR, and combinations thereof; (iii) at least one silicone-containing vinylic monomer or macromer, and (iv) optionally one or more components selected from the group consisting of a polymerization initiator, a chain transfer agent, and a solvent, wherein the mold has a lens-forming cavity between the molding surfaces, wherein the colored coat contains a first surface exposed to the interior of the lens-forming cavity and a second surface in contact with the molding surface; (b) curing the ink printed on the mold; (c) dispensing a silicone hydrogel lens-forming material into the lens-forming cavity of the mold; (d) curing the lens-forming material within the lens-forming cavity to form the contact lens, whereby the colored coat detaches from the molding surface and becomes integral with the body of the contact lens.

6. 发明公开

EP1561131A1 MOLDINGS AND PREPARATION AND USES THEREOF 审中-公开
标题翻译：形式和它们的制备和应用
公开(公告)号：EP1561131A1
公开(公告)日：2005-08-10
申请号：EP03788990.4
申请日：2003-10-31
申请人： Novartis AG , Novartis Pharma GmbH
发明人： PHELAN, John, Christopher , QUINN, Michael, Hugh
IPC分类号： G02B1/04 , C08B37/00 , C08F8/00
CPC分类号： C08F20/58 , C08B37/0021 , C08L5/02 , G02B1/043 , Y10S525/937
摘要： An ophthalmic lens comprising the cross-linked product of a first polymer, wherein said first polymer is a radiationcurable (meth)acrylamidoalkyl derivative of an oligomer or polymer containing a plurality of H-active groups, wherein said lens transmits at least 70% of visible light.

7. 发明公开

EP1534767A1 RADIATION-CURABLE PREPOLYMERS 有权
标题翻译：辐射固化预聚物
公开(公告)号：EP1534767A1
公开(公告)日：2005-06-01
申请号：EP03787788.3
申请日：2003-08-13
申请人： Novartis AG , Novartis Pharma GmbH
发明人： PHELAN, John, Christopher , QUINN, Michael, Hugh , WALLACH, Joshua, Andrew
IPC分类号： C08G18/67 , G02B1/04
CPC分类号： C08G18/672 , C08G18/678 , G02B1/043 , C08L75/04 , C08G18/6677
摘要： The present invention provides a radiation-curable prepolymer. The radiation-curable prepolymer of the invention is prepared by reacting an isocyanate-capped polyurethane with an ethylenically unsaturated amine or an ethylenically unsaturated monohydroxy compound or a mixture thereof, wherein the isocyanate-capped polyurethane is a copolymerization production of: (a) at least one polyalkylene glycol; (b) at least one branching agent having at least three hydroxy groups; and (c) at least one di- or polyisocyanate. The radiation-curable prepolymer of the invention can find use in economically producing contact lenses which have durable, highly elastic soft contact lenses with desired physical properties. In addition, the present invention provides method for making a radiation-curable prepolymer of the invention and for making a medical device, preferably an ophthalmic device, more preferably a contact lens.

8. 发明公开

EP1880185A2 AUTOMATED INSPECTION OF COLORED CONTACT LENSES 有权转让
标题翻译：有色镜片自动化测试
公开(公告)号：EP1880185A2
公开(公告)日：2008-01-23
申请号：EP06753476.8
申请日：2006-05-03
申请人： Novartis AG , NOVARTIS-PHARMA GMBH
发明人： TUCKER, Robert, Carey , QUINN, Michael, Hugh
IPC分类号： G01M11/02 , B29D11/00
CPC分类号： B29D11/00125 , B29D11/00317 , G01N21/958
摘要： The present invention relates to a method for automatically inspecting a colored print applied either on a mold or on a contact lens, comprising the steps of automatically aligning, in a precisely predetermined manner, by using centering and adjusting means, a camera with the mold half having the colore print on its molding surface; taking a picture with the camera, wherein the .picture comprises an image of the mold half having the colored print on its imolding surface or of the mold with the contact lens therein, wherein jpredetermined alignment of the camera with the mold ensures that the center jof the mold image is located substantially at a predetermined pixel in the jpicture; and analyzing by computing at least a pixel area corresponding to the colored print to determine if the coloreςj print applied onto the mold half or the contact lens has any defects.

9. 发明授权

EP1534767B1 RADIATION-CURABLE PREPOLYMERS 有权
标题翻译：辐射固化预聚物
公开(公告)号：EP1534767B1
公开(公告)日：2007-11-28
申请号：EP03787788.3
申请日：2003-08-13
申请人： Novartis AG , Novartis Pharma GmbH
发明人： PHELAN, John, Christopher , QUINN, Michael, Hugh , WALLACH, Joshua, Andrew
IPC分类号： C08G18/67 , G02B1/04
CPC分类号： C08G18/672 , C08G18/678 , G02B1/043 , C08L75/04 , C08G18/6677
摘要： The present invention provides a radiation-curable prepolymer. The radiation-curable prepolymer of the invention is prepared by reacting an isocyanate-capped polyurethane with an ethylenically unsaturated amine or an ethylenically unsaturated monohydroxy compound or a mixture thereof, wherein the isocyanate-capped polyurethane is a copolymerization production of: (a) at least one polyalkylene glycol; (b) at least one branching agent having at least three hydroxy groups; and (c) at least one di- or polyisocyanate. The radiation-curable prepolymer of the invention can find use in economically producing contact lenses which have durable, highly elastic soft contact lenses with desired physical properties. In addition, the present invention provides method for making a radiation-curable prepolymer of the invention and for making a medical device, preferably an ophthalmic device, more preferably a contact lens.

10. 发明公开

EP1763433A1 METHOD FOR LATHING SILICONE HYDROGEL LENSES 有权
标题翻译：车削方法的有机硅水凝胶镜片
公开(公告)号：EP1763433A1
公开(公告)日：2007-03-21
申请号：EP05758863.4
申请日：2005-06-29
申请人： Novartis AG , Novartis Pharma GmbH
发明人： PHELAN, John, Christopher , QUINN, Michael, Hugh , ANDINO, Rafael, Victor , ASH, Marcia, Kay , GILLIARD, Allen , JANKIEWICZ, Tomasz , MORGAN, Courtney, Flem , LINDACHER, Joseph, Michael , NICULAS, Cornelius, Daniel
IPC分类号： B29D11/00 , G02B1/04
CPC分类号： B29D11/00038 , B29C47/0021 , B29C47/0038 , B29C47/0057 , B29C69/001 , B29D11/00076 , B29D11/00932
摘要： The present invention provides methods for lathing at room temperature a silicone hydrogel material, in particular silicone hydrogel material having a high oxygen permeability and made of a polymerizable composition containing a relative large amount of oxyperm component, into contact lenses.

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