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1. 发明授权

EP2704795B1 VERIFICATION OF PRESSURE METRICS 有权
标题翻译：回顾压力度量的
公开(公告)号：EP2704795B1
公开(公告)日：2015-01-14
申请号：EP12722975.5
申请日：2012-05-02
申请人： Medtronic, Inc.
发明人： HAVEL, William, J. , BENNETT, Tommy D. , CHO, Yong Kyun , TAEPKE, II, Robert T.
IPC分类号： A61N1/37 , A61B5/024
CPC分类号： A61N1/3702 , A61B5/0215 , A61B5/686 , A61B5/7207 , A61B5/7239 , A61N1/36564

2. 发明授权

EP1572293B1 RESPIRATORY NERVE STIMULATION 有权
标题翻译：刺激神经的气息
公开(公告)号：EP1572293B1
公开(公告)日：2012-02-29
申请号：EP03779260.3
申请日：2003-10-27
申请人： Medtronic, Inc.
发明人： CASAVANT, David, A. , HAVEL, William, J.
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/3601 , A61N1/365 , A61N2001/0585
摘要： The invention is directed to an implantable medical device that stimulates a nerve associated with respiration. The nerve may, for example be a phrenic nerve, and the stimulation may cause a diaphragm of the patient to contract. The implantable medical device receives a signal that indicates a need for increased cardiac output and stimulates the nerve in response to the signal. The implantable medical device may receive such a signal by, for example, detecting a ventricular tachyarrhythmia, sensing a pressure that indicates a need for increased cardiac output, or receiving a signal from a patient via a patient activator. Stimulation of the nerve may increase cardiac output of a beating or defibrillating heart

3. 发明公开

EP1429839A2 IMPLANTABLE MEDICAL DEVICE FOR TREATING CARDIAC MECHANICAL DYSFUNCTION BY ELECTRICAL STIMULATION 审中-公开
标题翻译：植入式医疗设备，机械心脏功能障碍的电刺激治疗的
公开(公告)号：EP1429839A2
公开(公告)日：2004-06-23
申请号：EP02797838.6
申请日：2002-08-28
申请人： Medtronic, Inc.
发明人： DENO, Curtis, D. , HAVEL, William, J. , BENNETT, Tom, D. , STEIN, Paul, M. , EULER, David, E.
IPC分类号： A61N1/368 , A61N1/36 , A61N1/39
CPC分类号： A61N1/3956 , A61N1/36014 , A61N1/36114 , A61N1/3625 , A61N1/3627 , A61N1/36585 , A61N1/3706
摘要： The above-described methods and apparatus are believed to be of particular benefit for patients suffering heart failure including cardiac dysfunction, chronic HF, and the like and all variants as described herein and including those known to those of skill in the art to which the invention is directed. It will understood that the present invention offers the possibility of monitoring and therapy of a wide variety of acute and chronic cardiac dysfunctions. The current invention provides systems and methods for delivering therapy for cardiac hemodynamic dysfunction.

4. 发明公开

EP1713538A1 DETERMINING A COUPLING INTERVAL FOR A CARDIAC VULNERABLE ZONE 有权
标题翻译：确定心脏脆性区的耦合间隔
公开(公告)号：EP1713538A1
公开(公告)日：2006-10-25
申请号：EP04812793.0
申请日：2004-12-01
申请人： MEDTRONIC, INC.
发明人： HAVEL, William, J.
IPC分类号： A61N1/38
CPC分类号： A61N1/3962 , A61N1/3937
摘要： A method and apparatus for actively determining a coupling interval corresponding to a cardiac vulnerable zone associated with a therapy of an implantable medical device that includes a timing and control unit delivering, via electrodes of a plurality of electrodes, a first pulse train and a first pulse signal at a predetermined time interval from delivery of a last pulse of the first pulse train. A sensor determines an evoked response corresponding to the first pulse signal, and a microprocessor compares the evoked response to a prior determined evoked response and sets the coupling interval equal to the predetermined time interval in response to the latency of the evoked response having increased by a first predetermined amount, and reduces the predetermined time interval by a second predetermined amount in response to the latency of the evoked response not having increased by the first predetermined amount.
摘要翻译：一种用于主动确定对应于与可植入医疗设备的治疗相关联的心脏脆弱区的耦合间隔的方法和设备，所述方法和设备包括定时和控制单元，其经由多个电极的电极递送第一脉冲串和第一脉冲信号从传递第一脉冲串的最后一个脉冲起的预定时间间隔。传感器确定对应于第一脉冲信号的诱发响应，并且微处理器将诱发响应与先前确定的诱发响应进行比较，并且响应于诱发响应的等待时间增加a，将耦合间隔设置为等于预定时间间隔第一预定量，并且响应于诱发响应的延迟未增加第一预定量，将预定时间间隔减小第二预定量。

5. 发明公开

EP1455897A2 CONTROL OF ARBITRARY WAVEFORMS FOR CONSTANT DELIVERED ENERGY 审中-公开
标题翻译：，任何波形用于生成恒能量控制水平
公开(公告)号：EP1455897A2
公开(公告)日：2004-09-15
申请号：EP02804520.1
申请日：2002-12-03
申请人： Medtronic, Inc.
发明人： HAVEL, William, J. , DEGROOT, Paul, J. , SINNER, Thomas, W. , KUEHN, Kevin , KEMMETMUELLER, Gary , WOLD, Warren, W.
IPC分类号： A61N1/39
CPC分类号： A61N1/3906 , A61N1/3912 , A61N1/3937
摘要： The present invention outlines structures and methods for delivering a controllable amount of energy to a patient by automatically compensating for the load impedance detected by an implantable-cardioverter defibrillator (ICD). The invention employs high speed, switching power converter technology for the efficient generation of high energy, arbitrary waveforms. Unlike a linear amplifier, switching power converters deliver high-energy waveforms with an efficiency that is independent of the size and amplitude of the desired waveform. An ICD that uses a switching power converter to deliver the desired energy to the patient stores the energy to be delivered in a storage capacitor. The converter then transforms this energy into an arbitrarily shaped output voltage-controlled or current-controlled waveform by switching the storage capacitor in and out of the output circuit at a high rate of speed. Preferably, the waveform comprises a ramp-type waveform.

6. 发明授权

EP1713538B1 DETERMINING A COUPLING INTERVAL FOR A CARDIAC VULNERABLE ZONE 有权
标题翻译：确定心脏脆性区的耦合间隔
公开(公告)号：EP1713538B1
公开(公告)日：2010-07-07
申请号：EP04812793.0
申请日：2004-12-01
申请人： Medtronic, Inc.
发明人： HAVEL, William, J.
IPC分类号： A61N1/38
CPC分类号： A61N1/3962 , A61N1/3937

7. 发明公开

EP1986736A1 IMPLANTABLE SUBCUTANEOUS MEDICAL DEVICE PROVIDING POST-EXTRA-SYSTOLIC POTENTIATION THERAPY 审中-公开
标题翻译：提供术后体外强化治疗的可植入式皮下注射医疗装置
公开(公告)号：EP1986736A1
公开(公告)日：2008-11-05
申请号：EP07710285.3
申请日：2007-01-24
申请人： MEDTRONIC, INC.
发明人： DENO, Curtis, D. , HAVEL, William, J.
IPC分类号： A61N1/365 , A61N1/37 , A61N1/39
CPC分类号： A61N1/36514 , A61N1/36528 , A61N1/36542 , A61N1/3702 , A61N1/3962
摘要： An ICD system adapted for subcutaneous implantation, the system comprising: a pair of electrodes adapted to deliver electrical stimulation to a heart; a set of low polarization electrodes for sensing a response to electrical potentiation pulses delivered from the first pair of electrodes; and a counter for logging a duration of fast VT and VF between high voltage shocks that restore normal sinus rhythm to the heart, the shocks delivered by the first pair of electrodes.
摘要翻译：一种适用于皮下植入的ICD系统，该系统包括：一对电极，适于向心脏输送电刺激; 一组低极化电极，用于感测对从第一对电极传递的电增强脉冲的响应; 以及用于在高电压冲击之间记录快速VT和VF持续时间的计数器，所述高电压冲击恢复正常窦性心律至第一对电极所传递的冲击。

8. 发明公开

EP2367596A1 SHUNT-CURRENT REDUCTION HOUSING FOR AN IMPLANTABLE THERAPY SYSTEM 审中-公开
标题翻译：分流电流还原住房的可植入治疗系统
公开(公告)号：EP2367596A1
公开(公告)日：2011-09-28
申请号：EP09753273.3
申请日：2009-10-30
申请人： Medtronic, Inc.
发明人： DONOFRIO, William, T. , HAVEL, William, J. , CHRISTIANSEN, Chris, C. , KRAUSE, Paul, G.
IPC分类号： A61N1/37 , A61N1/375 , A61N1/08 , A61N1/372 , A61N1/39
CPC分类号： A61N1/375 , A61N1/08 , A61N1/36114 , A61N1/37 , A61N1/3718 , A61N1/37211 , A61N1/37288 , A61N1/3925 , A61N1/3962
摘要： Techniques for minimizing interference between first and second medical devices of a therapy system may include providing an outer housing for at least one of the medical devices that comprises an electrically insulative layer formed over at least the electrically conductive portions (e.g., an electrically conductive layer) of the housing, or providing an electrically insulative pouch around an electrically conductive housing of at least the first medical device. The electrically insulative layer or electrically insulative pouch may reduce or even eliminate shunt-current that flows into the medical device via the housing. The shunt-current may be generated by the delivery of electrical stimulation by the second medical device. In some examples, the techniques may also include shunt-current mitigation circuitry that helps minimize or even eliminate shunt-current that feeds into the first medical device via one or more electrodes electrically connected to the first medical device.

9. 发明公开

EP2344246A2 SUBCUTANEOUS IMPLANTABLE LEAD WITH LEADING END 审中-公开
标题翻译：与前端皮下植入引线，
公开(公告)号：EP2344246A2
公开(公告)日：2011-07-20
申请号：EP09790714.1
申请日：2009-07-22
申请人： Medtronic, Inc.
发明人： HAVEL, William, J. , LAZEROMS, Markus, J. , RUTTEN, Jean Joseph, Gerardus , SMITS, Karel, F.A.A.
IPC分类号： A61N1/39 , A61N1/05
CPC分类号： A61N1/0504 , A61N1/3962
摘要： A subcutaneous implantable device is provided that includes a defibrillation electrode disposed along a portion of a lead, and a lead tip connected to the lead. The lead tip includes a trailing end coupled to a distal end of the lead, and first and second non-parallel sides extending from the trailing end that converge to a leading end that is configured to wedge between tissue layers as the lead is advanced subcutaneously.

10. 发明公开

EP2344054A1 MEDICAL DEVICE SYSTEM AND APPARATUS FOR GUIDING THE PLACEMENT OF A SUBCUTANEOUS DEVICE 审中-公开
标题翻译：医疗设备系统和装置用于实现皮下设备的位置
公开(公告)号：EP2344054A1
公开(公告)日：2011-07-20
申请号：EP09790252.2
申请日：2009-07-10
申请人： Medtronic, Inc.
发明人： HAVEL, William, J. , NIKOLSKI, Vladimir, P.
IPC分类号： A61B17/34
CPC分类号： A61B17/3468 , A61B17/3462 , A61B17/3472 , A61B2017/00026 , A61B2017/0003 , A61B2017/00561 , A61B2017/306 , A61B2017/320044 , A61B2017/320056 , A61M5/425 , A61M5/427 , A61M2005/1586 , A61N1/046 , A61N1/0504
摘要： A medical device system (300) for advancing a subcutaneous device to a desired implant site that includes a strap (302) extending along a length from a proximal end (311) to a distal end (313), a first curved flange (303) and a second curved flange (305) extending along a portion of the length of the strap (302), a base portion (306) extending along a portion of the length of the strap (302) between the first curved flange (303) and the second curved flange (305), and an indentation (304) extending from the proximal end (311) to the distal end (313)of the strap (302), the indentation (304)formed by the first curved flange (303), the second curved flange (305), and the base portion (306), wherein the first curved flange (303) and the second curved flange (305) include curved bottom portions (320) that make contact with and compress a tissue layer (372, 374) to position the tissue layer (372,374) within the indentation (304) during the placement of the subcutaneous device, such as a coil electrode for an implantable cardioverter defibrillator (ICD).

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