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2. 发明授权

EP3185954B1 ENERGY ADAPTIVE COMMUNICATION FOR MEDICAL DEVICES 有权
公开(公告)号：EP3185954B1
公开(公告)日：2018-11-28
申请号：EP15757632.3
申请日：2015-08-26
申请人： Cardiac Pacemakers, Inc.
发明人： STAHMANN, Jeffrey E. , HUELSKAMP, Paul , KANE, Michael J. , MAILE, Keith R.
IPC分类号： A61N1/375 , A61N1/372 , A61N1/37
CPC分类号： A61N1/37288 , A61N1/371 , A61N1/37217 , A61N1/37241 , A61N1/37276 , A61N1/3756 , A61N1/3956
摘要： System and methods for energy adaptive communications between medical devices are disclosed. In one example, a medical device includes a communication module configured to deliver a plurality of pulses to tissue of a patient, where each pulse has an amount of energy. A control module operatively coupled to the communication module, may be configured to, for each delivered pulse, determine whether the delivered pulse produces an unwanted stimulation of the patient and to change the amount of energy of the plurality of pulses over time so as to identify an amount of energy that corresponds to an unwanted stimulation threshold for the pulses. The control module may then set a maximum energy value for communication pulses that is below the unwanted stimulation threshold, and may deliver communication pulses below the maximum energy value during communication with another medical device.

3. 发明公开

EP3389775A1 CONDUCTED COMMUNICATION IN A MEDICAL DEVICE SYSTEM 有权
公开(公告)号：EP3389775A1
公开(公告)日：2018-10-24
申请号：EP16845317.3
申请日：2016-12-16
申请人： Cardiac Pacemakers, Inc.
发明人： KANE, Michael J. , SCHMIDT, Brian L. , KOOP, Brendan Early
IPC分类号： A61N1/372
CPC分类号： A61N1/37288 , A61N1/362 , A61N1/37217 , A61N1/3756
摘要： An implantable medical device for implantation into a patient may include a housing, a pulse generation circuit disposed at least partially within the housing, a plurality of electrodes electrically coupled to the pulse generation circuit, the plurality of electrodes being exposed external to the housing, and a controller operatively coupled to the pulse generation circuit. The controller may be configured to command the pulse generation circuit to deliver a phasic conducted communication pulse via at least two of the plurality of electrodes. Additionally, the phasic conducted communication pulse may comprise a first phase having a first polarity followed by a second phase having an opposite second polarity, wherein the second phase may have a duration of less than 60 microseconds, and wherein the first phase having may have a duration of between five percent and eighty percent of the duration of the second phase.

4. 发明公开

EP3348306A1 CARDIAC PACING SYSTEM COMPRISING AN IMPLANTABLE LEADLESS PACEMAKER AND AN IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR 审中-公开
公开(公告)号：EP3348306A1
公开(公告)日：2018-07-18
申请号：EP17156692.0
申请日：2017-02-17
申请人： BIOTRONIK SE & Co. KG
发明人： Müssig, Dirk , Stotts, Larry
IPC分类号： A61N1/375 , A61N1/372 , A61N1/39
CPC分类号： A61N1/3756 , A61N1/37282 , A61N1/37288 , A61N1/3956 , A61N1/3987
摘要： The present invention relates to a cardiac pacemaking system (1), comprising: an implantable leadless pacemaker (10) that is configured to be implanted into a chamber of a patient's heart (2), and an implantable subcutaneous cardioverter-defibrillator (20), wherein the leadless pacemaker (10) is configured to apply electrical pacing pulses to the heart (2), particularly in order to provide antibradycardia pacing, and wherein the subcutaneous cardioverter-defibrillator (20) is configured to apply electrical stimulation to the heart (2) for providing defibrillation of the heart (2), and wherein the leadless pacemaker (10) is configured to sense the patient's heart rhythm, and wherein the cardiac pacemaking system (1) comprises a communication link (101) between the leadless pacemaker (10) and the subcutaneous cardioverter-defibrillator (20), wherein the leadless pacemaker (10) is configured to send an output signal to the subcutaneous cardioverter-defibrillator (20) via said communication link (101) in an unidirectional fashion when the leadless pacemaker (10) detects a heart rhythm that requires said electrical stimulation of the subcutaneous cardioverter-defibrillator (20), and wherein the subcutaneous cardioverter-defibrillator (20) is configured to apply said electrical stimulation to the heart (2) when the subcutaneous cardioverter-defibrillator (20) receives said output signal.

5. 发明授权

EP2178238B1 Insuring proper communication with chosen implant among multiple implants in proximity to one another 有权
公开(公告)号：EP2178238B1
公开(公告)日：2018-07-18
申请号：EP09252415.6
申请日：2009-10-15
申请人： Codman Neurosciences Sarl
发明人： Crivelli, Rocco , Ginggen, Alec
IPC分类号： H04L1/00 , A61N1/372
CPC分类号： H04L1/0072 , A61N1/37288 , H04L1/0061
摘要： A system and method for restricting proper regulation by a control unit of only the functionality of the targeted device whose operations are intended to be programmed so as to insure no adverse regulation of functionality with respect to any other non-targeted device. A memory associated with each of the control device and the targeted device stores a unique identification assigned to that targeted device compressed using an error detection scheme, wherein the compressed unique identification has a length less than or equal to that of each of the messages. Circuitry, such as a logic function, mixes the stored compressed unique identification with each message transmitted between the two devices subsequent to receipt of a response signal from the targeted device to an interrogation command from the control device to insure proper communication between the control device and the targeted device.

6. 发明授权

EP2838608B1 APPARATUS FOR ARTIFICIAL CARDIAC STIMULATION 有权转让
公开(公告)号：EP2838608B1
公开(公告)日：2018-06-13
申请号：EP13723185.8
申请日：2013-04-10
申请人： Gloucestershire Hospitals NHS Foundation Trust
发明人： NUTA, Bogdan , LINES, Ian
IPC分类号： A61N1/368 , A61N1/372 , A61N1/375
CPC分类号： A61N1/056 , A61F2/82 , A61F2250/001 , A61N1/368 , A61N1/3684 , A61N1/37288 , A61N1/3756 , A61N2001/0585
摘要： A system for artificial stimulation of the heart of a subject is provided, the system comprising a controller comprising a receiver for receiving signal data, a processor for processing received signal data, and a transmitter for transmitting signal data; a sensing stent for location in the proximal coronary sinus of the subject, the sensing stent electrode comprising a sensing electrode assembly for sensing atrial and/or ventricular signals from the heart of the subject and a transmitting assembly for transmitting signal data to the receiver of the controller; and a stimulation stent for location in a vein of the subject distal of the sensing stent, the stimulation stent comprising a receiver for receiving signal data from the transmitter of the controller and an electrode assembly for providing a stimulating electrical signal to the heart of the subject in response to the data received.

7. 发明公开

EP3313269A1 SYSTEMS AND METHODS FOR NORMALIZATION OF CHEMICAL SENSOR DATA BASED ON FLUID STATE CHANGES 审中-公开
标题翻译：基于流体状态变化的化学传感器数据标准化的系统和方法
公开(公告)号：EP3313269A1
公开(公告)日：2018-05-02
申请号：EP16741428.3
申请日：2016-06-23
申请人： Cardiac Pacemakers, Inc.
发明人： STAHMANN, Jeffrey E.
IPC分类号： A61B5/00 , A61N1/372 , A61B5/145 , A61B5/1459 , A61B5/08 , A61B5/11 , A61N1/36
CPC分类号： A61B5/1473 , A61B5/0031 , A61B5/01 , A61B5/05 , A61B5/08 , A61B5/1116 , A61B5/1118 , A61B5/14503 , A61B5/14532 , A61B5/14546 , A61B5/1459 , A61B5/686 , A61B5/6861 , A61B5/7221 , A61B5/746 , A61B2562/0219 , A61N1/36 , A61N1/36557 , A61N1/37288
摘要： Embodiments herein include implantable medical systems, devices and methods including chemical sensors. In an embodiment, an implantable medical device system includes a chemical sensor; a fluid state sensor such as a posture sensor; an activity sensor; and/or a respiration sensor. The implantable medical device system can further include normalization circuitry receiving data from the chemical sensor and the fluid state sensor and normalizing the chemical sensor data based on data from the fluid state sensor. In an embodiment, a method of operating an implantable medical device system is included. The method can include measuring the amount of a chemical analyte using a chemical sensor, measuring the fluid status in a patient using a fluid state sensor, and normalizing the measured amount of the chemical analyte as indicated by the chemical sensor using normalization circuitry based on data from the fluid state sensor. Other embodiments are also included herein.

8. 发明公开

EP3305362A2 METHOD AND APPARATUS FOR NONINVASIVE INHIBITION OF DEEP VEIN THROMBOSIS 审中-公开
标题翻译：非侵入性抑制深静脉血栓形成的方法和装置
公开(公告)号：EP3305362A2
公开(公告)日：2018-04-11
申请号：EP17190046.7
申请日：2017-09-08
申请人： StimMed LLC
发明人： Kaplan, Robert Edward , Czymy, James Joseph , Friedman, Scott E.
IPC分类号： A61N1/04 , A61N1/36
CPC分类号： A61N1/04 , A61N1/0456 , A61N1/0484 , A61N1/0492 , A61N1/205 , A61N1/36 , A61N1/36003 , A61N1/36021 , A61N1/37288
摘要： System, device and method for providing neuromuscular electrical stimulation (NMES) to muscles of foot. The device includes an electrical signal generator for producing a wave pattern of variable frequency, duration, intensity, ramp time and on-off cycle. The device further includes surface electrodes for being positioned over the foot muscles or around ankles and attached to the signal generator. The device includes a wearable device for positioning a first electrode adjacent a heel of the wearer's foot and a second electrode adjacent an arch of the foot. The signal generator is programmed to stimulate the foot muscles and nerves. Location of the electrodes and the programming are adjusted to reduce pooling of the blood in the soleal veins of the calf and enhance venous blood flow to prevent deep vein thrombosis (DVT); to enhance venous blood flow for the post-thrombotic syndrome patient; to expedite wound healing; to reduce neuropathic pain of the foot and ankle, chronic musculoskeletal pain of the ankle and foot, and acute post-operative foot and ankle pain; and to prevent muscular atrophy of the foot muscles.
摘要翻译：用于向脚部肌肉提供神经肌肉电刺激（NMES）的系统，装置和方法。该设备包括一个电信号发生器，用于产生可变频率，持续时间，强度，斜坡时间和开关周期的波形。该装置还包括用于定位在脚部肌肉上或脚踝周围并连接到信号发生器的表面电极。该装置包括用于将第一电极定位在穿用者脚的脚跟附近的第一电极以及邻近脚的足弓的第二电极。信号发生器被编程为刺激脚部肌肉和神经。调整电极的位置和编程以减少小腿近端静脉血液的汇集并增强静脉血流量以防止深静脉血栓形成（DVT）; 增强血栓形成后综合征患者的静脉血流量; 加速伤口愈合; 减少足部和脚踝的神经性疼痛，脚踝和脚部的慢性肌肉骨骼疼痛以及术后急性脚和脚踝疼痛; 并防止脚部肌肉的肌肉萎缩。

9. 发明公开

EP3177363A1 MEDICAL DEVICE FOR COMMUNICATION WITH AN IMPLANTABLE LEADLESS CARDIAC PACEMAKER ONLY DURING TIMES BETWEEN BLANKING PERIODS 有权
标题翻译：医疗设备，通信的方式与导联松动植入起搏器只有在时代的消隐期之间
公开(公告)号：EP3177363A1
公开(公告)日：2017-06-14
申请号：EP15756705.8
申请日：2015-07-30
申请人： Cardiac Pacemakers, Inc.
发明人： MAILE, Keith R. , KANE, Michael J. , HUELSKAMP, Paul , JUFFER, Lance E. , STAHMANN, Jeffrey E.
IPC分类号： A61N1/37 , A61N1/372 , A61N1/39 , A61B5/0402
CPC分类号： A61N1/37217 , A61B5/0402 , A61N1/3702 , A61N1/37252 , A61N1/37288 , A61N1/3756 , A61N1/3956 , G16H40/63
摘要： Systems and methods for communicating between medical devices. In on example, a medical device comprises a communication module for communicating with an implantable leadless cardiac pacemaker through body tissue and a controller operatively coupled to the communications module. The controller may be configured to: identify intrinsic heartbeats; provide a blanking period after each occurrence of an intrinsic heartbeat; and communicate with the implantable leadless cardiac pacemaker via the communication module only during times between the blanking periods.
摘要翻译：系统和医疗设备之间传送的方法。在一个示例中，医疗设备包括：用于通过身体组织和可操作地耦合到所述通信模块的控制器在无引线植入式心脏起搏器与通信的通信模块。该控制器可以被配置为：识别固有心跳; 提供本征心跳每次出现之后的消隐期间; 并且仅在消隐周期之间的时间与通过通信模块可植入无引线心脏起搏器通信。

10. 发明公开

EP3171937A1 ATRIAL CONTRACTION DETECTION BY A VENTRICULAR LEADLESS PACING DEVICE FOR ATRIO-SYNCHRONOUS VENTRICULAR PACING 有权
标题翻译：心房收缩的检测用铅LOOSE心室起搏心房心室同步一步一步
公开(公告)号：EP3171937A1
公开(公告)日：2017-05-31
申请号：EP15745664.1
申请日：2015-07-17
申请人： Medtronic, Inc.
发明人： CHO, Yong K. , SAMBELASHVILI, Aleksandre T. , SHELDON, Todd J.
IPC分类号： A61N1/372 , A61N1/375 , A61N1/362
CPC分类号： A61N1/36578 , A61N1/3621 , A61N1/36585 , A61N1/3682 , A61N1/3684 , A61N1/37288 , A61N1/3756
摘要： A leadless pacing device (LPD) includes a motion sensor configured to generate a motion signal as a function of heart movement. The LPD is configured to analyze the motion signal within an atrial contraction detection window that begins an atrial contraction detection delay period after activation of the ventricle, and detect a contraction of an atrium of the heart based on the analysis of the motion signal within the atrial contraction detection window. If the LPD does not detect a ventricular depolarization subsequent to the atrial contraction, e.g., with an atrio-ventricular (AV) interval beginning when the atrial contraction was detected, the LPD delivers a ventricular pacing pulse.
摘要翻译：无引线起搏设备（LPD）包括被配置为生成运动信号作为心脏运动的功能的运动传感器。该LPD被配置为分析内的心房收缩的检测窗口中的运动信号做了脑室的激活之后开始的心房收缩的检测延迟时间，并检测基于所述心房中的运动信号的分析的心脏的心房的收缩收缩检测窗口。如果当检测到该心房收缩，LPD传递心室起搏脉冲的LPD没有检测到心室去极化之后心房收缩，E. G.，与房室（AV）间隔开始。

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