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1. 发明公开

EP3073948A4 SYSTEMS, METHODS, AND DEVICES HAVING STRETCHABLE INTEGRATED CIRCUITRY FOR SENSING AND DELIVERING THERAPY 审中-公开
标题翻译： SYSTEME，VERFAHREN UND VORRICHTUNGEN MIT DEHNBARER INTEGRIERTER SCHALTUNGFÜRMESSUNG UND THERAPIEVERABREICHUNG
公开(公告)号：EP3073948A4
公开(公告)日：2017-08-16
申请号：EP14866307
申请日：2014-11-24
申请人： MC10 INC
发明人： GHAFFARI ROOZBEH
IPC分类号： A61B18/02
CPC分类号： A61B5/683 , A61B1/05 , A61B5/0024 , A61B5/0031 , A61B5/0059 , A61B5/01 , A61B5/03 , A61B5/04087 , A61B5/053 , A61B5/6821 , A61B5/6833 , A61B5/6847 , A61B5/6869 , A61B5/743 , A61B8/12 , A61B18/02 , A61B18/14 , A61B18/1492 , A61B18/1815 , A61B18/20 , A61B18/24 , A61B2018/0016 , A61B2018/0022 , A61B2018/00339 , A61B2018/00351 , A61B2018/00577 , A61B2018/00839 , A61B2018/0212 , A61B2562/164 , A61B2562/166 , A61N7/022 , H01L27/14618 , H01L27/14632 , H01L27/14645 , H01L27/14687 , H01L27/14692 , H01L2924/0002 , H01L2924/1433 , H01L2924/19041 , H01L2924/19042 , H01L2924/19043 , H01L2924/30105 , H01L2924/00

2. 发明公开

EP3071096A4 CONFORMAL SENSOR SYSTEMS FOR SENSING AND ANALYSIS OF CARDIAC ACTIVITY 审中-公开
标题翻译： KEMFORME SENSORSYSTEME ZUR MESSUNG UND ANALYZE DERHERZAKTIVITÄT
公开(公告)号：EP3071096A4
公开(公告)日：2017-08-09
申请号：EP14863481
申请日：2014-11-21
申请人： MC10 INC
发明人： HUPPERT GILBERT LEE , GHAFFARI ROOZBEH , CERUOLO MELISSA , KEEN BRYAN , RAJ MILAN , MCGRANE BRYAN
IPC分类号： A61B5/00
CPC分类号： A61B5/6833 , A61B5/0006 , A61B5/0022 , A61B5/01 , A61B5/02028 , A61B5/0205 , A61B5/02055 , A61B5/02444 , A61B5/0408 , A61B5/04085 , A61B5/04087 , A61B5/0476 , A61B5/0488 , A61B5/08 , A61B5/4815 , A61B5/4839 , A61B5/486 , A61B5/4866 , A61B5/4875 , A61B5/7271 , A61B2560/0214 , A61B2560/0475 , A61B2562/0219 , A61B2562/08 , A61B2562/164 , A61M37/00
摘要： Systems, methods and apparatuses for monitoring cardiac activity of an individual using a conformal cardiac sensor device are presented herein. A conformal cardiac sensor device for analyzing cardiac activity includes a flexible substrate for coupling to the user, and a heart sensor component embedded on/in the substrate. The heart sensor component contacts a portion of the users skin and measures electrical variable(s) indicative of cardiac activity. A biometric sensor component is embedded on/in the flexible substrate and measures physiological variable(s) indicative of cardiac activity of the user. A microprocessor, which is embedded on/in the flexible substrate, is communicatively coupled to the heart sensor component and biometric sensor component and operable to execute microprocessor executable instructions for controlling the measurements of electrical data and physiological data. A wireless communication component is embedded on/in the flexible substrate and is operable to transmit data indicative of the measurements obtained by the sensor components.
摘要翻译：本文给出了使用共形心脏传感器装置监测个体的心脏活动的系统，方法和装置。用于分析心脏活动的共形心脏传感器装置包括用于耦合到用户的柔性衬底以及嵌入衬底上/中的心脏传感器部件。心脏传感器组件接触用户皮肤的一部分并且测量指示心脏活动的电变量。生物测定传感器组件被嵌入在柔性基底上/中并且测量指示用户的心脏活动的生理变量。嵌入在柔性衬底之上/之中的微处理器可通信地耦合到心脏传感器组件和生物测定传感器组件，并且可操作用于执行用于控制电数据和生理数据的测量结果的微处理器可执行指令。无线通信组件嵌入在柔性衬底上/内，并且可操作以传输指示由传感器组件获得的测量的数据。

3. 发明公开

EP2386117A4 METHODS AND APPLICATIONS OF NON-PLANAR IMAGING ARRAYS 审中-公开
公开(公告)号：EP2386117A4
公开(公告)日：2017-12-27
申请号：EP10729657
申请日：2010-01-12
申请人： MC10 INC
发明人： DE GRAFF BASSEL , CALLSEN GILMAN , ARORA WILLIAM J , GHAFFARI ROOZBEH
IPC分类号： H01L25/04 , H01L27/146
CPC分类号： H01L25/042 , H01L27/14685 , H01L2224/24137 , H01L2224/82 , H01L2224/83 , H01L2924/0002 , H01L2924/3011 , H01L2924/3512 , H01L2924/00
摘要： System, devices and methods are presented that provide an imaging array fabrication process method, comprising fabricating an array of semiconductor imaging elements, interconnecting the elements with stretchable interconnections, and transfer printing the array with a pre-strained elastomeric stamp to a secondary non-planar surface.

4. 发明公开

EP2866645A4 CATHETER DEVICE INCLUDING FLOW SENSING 审中-公开
标题翻译： KATHETERVORRICHTUNG MIT DURCHFLUSSMESSUNG
公开(公告)号：EP2866645A4
公开(公告)日：2016-03-30
申请号：EP13813046
申请日：2013-03-15
申请人： MC10 INC
发明人： KLINKER LAUREN E , GHAFFARI ROOZBEH , WORK JOHN , QUIVIRA FERNANDO , LIU CLIFFORD M , LEE STEPHEN
IPC分类号： A61B5/02 , A61B18/00 , A61B18/14
CPC分类号： A61B18/1492 , A61B18/02 , A61B18/06 , A61B18/18 , A61B18/1815 , A61B18/22 , A61B90/30 , A61B2018/00041 , A61B2018/00178 , A61B2018/0022 , A61B2018/00267 , A61B2018/00273 , A61B2018/00375 , A61B2018/00386 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00541 , A61B2018/00577 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00791 , A61B2018/00815 , A61B2018/00821 , A61B2018/00839 , A61B2018/00863 , A61B2018/0212 , A61B2018/1861 , A61B2090/065 , A61N1/0551 , A61N1/36017 , A61N1/36117 , A61N7/02
摘要： Devices and methods are provided for performing an ablation procedure on tissue with flow monitoring using flow sensors. The devices include a catheter, and at least one flow sensor disposed on the catheter, and a component for applying the ablation procedure. An assessment module provides an indication of the efficacy of the ablation procedure based on the flow measurement from the flow sensor.
摘要翻译：提供了设备和方法，用于使用流量传感器对具有流量监测的组织进行消融程序。所述装置包括导管，以及设置在导管上的至少一个流量传感器和用于施加消融程序的部件。评估模块基于来自流量传感器的流量测量提供消融程序的功效的指示。

5. 发明公开

EP2404171A4 SYSTEMS, METHODS, AND DEVICES HAVING STRETCHABLE INTEGRATED CIRCUITRY FOR SENSING AND DELIVERING THERAPY 审中-公开
标题翻译：系统，设备和方法可伸展集成电路用于测量和治疗施予
公开(公告)号：EP2404171A4
公开(公告)日：2016-01-27
申请号：EP10749458
申请日：2010-03-12
申请人： MC10 INC
发明人： DE GRAFF BASSEL , GHAFFARI ROOZBEH , ARORA WILLIAM J
IPC分类号： G01N33/48 , A61B5/04 , A61B18/02 , A61B18/04 , A61B18/14 , A61B18/24 , A61N7/00
CPC分类号： A61B5/4312 , A61B5/0002 , A61B5/0091 , A61B5/04001 , A61B5/0422 , A61B5/4041 , A61B5/4514 , A61B5/6831 , A61B5/6853 , A61B5/6882 , A61B18/02 , A61B18/082 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00022 , A61B2018/0022 , A61B2018/00351 , A61B2018/00839 , A61B2018/0212 , A61B2562/02 , A61B2562/0209 , A61B2562/0233 , A61B2562/0247 , A61B2562/046 , A61B2562/12 , A61B2562/164 , A61N7/022 , H01L27/14601 , H01L2224/18
摘要： System, devices and methods are presented that integrate stretchable or flexible circuitry, including arrays of active devices for enhanced sensing, diagnostic, and therapeutic capabilities. The invention enables conformal sensing contact with tissues of interest, such as the inner wall of a lumen, a the brain, or the surface of the heart. Such direct, conformal contact increases accuracy of measurement and delivery of therapy. Further, the invention enables the incorporation of both sensing and therapeutic devices on the same substrate allowing for faster treatment of diseased tissue and fewer devices to perform the same procedure.

6. 发明公开

EP3117206A4 QUANTIFICATION OF A CHANGE IN ASSAY 审中-公开
公开(公告)号：EP3117206A4
公开(公告)日：2017-11-15
申请号：EP15761784
申请日：2015-03-12
申请人： MC10 INC
发明人： GHAFFARI ROOZBEH , ARANYOSI ALEXANDER , LEE STEPHEN
IPC分类号： G01N21/27 , B01L3/00 , G01N21/77 , G01N35/00
CPC分类号： G01N21/272 , B01L3/502715 , B01L3/5055 , B01L2200/025 , B01L2300/023 , B01L2300/0636 , B01L2300/0816 , B01L2300/0864 , G01N35/00871 , G01N2021/7783 , G01N2035/00881
摘要： The present invention relates to portable devices for point-of-care diagnostics that can perform measurements on a sample (e.g., blood, serum, saliva, or urine) and relay data to an external device for, e.g., data analysis. The device can comprise a paper-based diagnostic substrate and a base substrate that include electronic circuitry and electronic elements necessary for performing the measurements. The device can also comprise an antenna for near field communication with an external device. Another aspect of the invention relates to methods of using these devices.

7. 发明公开

EP2556392A4 METHODS AND APPARATUS FOR MEASURING TECHNICAL PARAMETERS OF EQUIPMENT, TOOLS AND COMPONENTS VIA CONFORMAL ELECTRONICS 审中-公开
标题翻译：方法和设备测量设备，工具，技术参数及零部件，一致的电子
公开(公告)号：EP2556392A4
公开(公告)日：2014-03-19
申请号：EP11766768
申请日：2011-04-07
申请人： MC10 INC
发明人： DE GRAFF BASSEL , ARORA WILLIAM J , GHAFFARI ROOZBEH , CALLSEN GILMAN , DOWLING KEVIN
IPC分类号： G01D9/00
CPC分类号： G01D9/005

8. 发明公开

EP2349440A4 CATHETER BALLOON HAVING STRETCHABLE INTEGRATED CIRCUITRY AND SENSOR ARRAY 有权转让
标题翻译：加泰罗尼亚麻省理工学院
公开(公告)号：EP2349440A4
公开(公告)日：2014-03-19
申请号：EP09819838
申请日：2009-10-07
申请人： MC10 INC
发明人： GHAFFARI ROOZBEH , CALLSEN GILMAN , ARORA WILLIAM J , SCHLATKA BENJAMIN
IPC分类号： A61M29/00 , A61B5/00 , A61F2/00
CPC分类号： A61B5/4836 , A61B1/00082 , A61B1/3137 , A61B5/01 , A61B5/015 , A61B5/02007 , A61B5/02014 , A61B5/0536 , A61B5/6853 , A61B5/7271 , A61F2/958 , A61M25/10 , A61M2025/1086
摘要： A system, device and method are presented for utilizing stretchable active integrated circuits with inflatable bodies. The invention allows for such operative features to come into direct contact with body structures, such as the inner wall of a lumen. Such direct contact increases accuracy of measurement and delivery of therapy.
摘要翻译：提出了一种利用具有可充气体的可拉伸有源集成电路的系统，装置和方法。本发明允许这样的操作特征与身体结构（诸如内腔的内壁）直接接触。这种直接接触增加了治疗的测量和传递的准确性。

9. 发明公开

EP2509497A4 METHODS AND APPARATUS FOR CONFORMAL SENSING OF FORCE AND/OR CHANGE IN MOTION 审中-公开
标题翻译：方法和柔顺的检测力和/或变化运动器械
公开(公告)号：EP2509497A4
公开(公告)日：2014-02-05
申请号：EP10842663
申请日：2010-12-17
申请人： MC10 INC
发明人： CALLSEN GILMAN , GHAFFARI ROOZBEH , ARORA WILLIAM J , DE GRAFF BASSEL , SCHLATKA BENJAMIN , CARBECK JEFFREY D
IPC分类号： A61B5/11
CPC分类号： A61B5/11 , A42B3/046 , A61B5/6803 , A61B5/6814 , A61B5/6833 , A61B7/003 , A61B2562/0219 , A61B2562/0247 , A61B2562/164

10. 发明公开

EP3089656A4 INTEGRATED DEVICES FOR LOW POWER QUANTITATIVE MEASUREMENTS 审中-公开
标题翻译： INTEGRIERTE VORRICHTUNGENFÜR定量NIEDERSTROMMESSUNGEN
公开(公告)号：EP3089656A4
公开(公告)日：2017-09-06
申请号：EP15733190
申请日：2015-01-02
申请人： MC10 INC
发明人： GHAFFARI ROOZBEH , LEE STEPHEN
IPC分类号： A61B5/00 , G01N33/00 , G01N33/49 , H02J7/34 , H02J50/20 , H04B5/00
CPC分类号： H02J7/025 , G01N33/00 , G01N33/49 , G01N33/66 , H02J5/005 , H02J7/345 , H02J50/00 , H02J50/20 , H04B5/0037 , H04B5/0062 , H04B5/0081
摘要： A device includes a wirelessly enabled energy harvesting device, an energy storage component, a DC-DC converter, and a functional circuit. The energy storage component is electrically coupled to the wirelessly enabled energy harvesting device for storing energy harvested by the wirelessly enabled energy harvesting device from a wireless transmitting device positioned adjacent to the device. The DC-DC converter is electrically coupled to the energy storage component for receiving a voltage output from the energy storage component and converting the received voltage output to a second voltage level to provide power to one or more components of the device. The functional circuit is for measuring a concentration of a substance in a fluid sample. The functional circuit is coupled to the DC-DC converter such that the functional circuit obtains at least a portion of the power provided by the DC-DC converter.
摘要翻译：一种装置包括无线启用能量收集装置，能量存储组件，DC-DC转换器和功能电路。能量存储部件电耦合到无线使能能量收集设备，用于存储由无线使能能量收集设备从位于设备附近的无线发射设备收集的能量。 DC-DC转换器电耦合到能量存储部件，用于接收来自能量存储部件的电压输出并将接收到的电压输出转换成第二电压电平以向设备的一个或多个部件提供电力。功能电路用于测量流体样品中物质的浓度。功能电路耦合到DC-DC转换器，使得功能电路获得由DC-DC转换器提供的功率的至少一部分。

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