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1. 发明授权

EP2681544B1 BIOSENSOR ARRAY FORMED BY JUNCTIONS OF FUNCTIONALIZED SENSOR HALF ELEMENTS 失效
标题翻译： ARRAY MADE OUT节点指向官能化电极
公开(公告)号：EP2681544B1
公开(公告)日：2015-06-17
申请号：EP12707463.1
申请日：2012-02-27
申请人： Lexogen GmbH
发明人： REDA, Torsten , HAGLMÜLLER, Jakob , SCHITTER, Georg , SEITZ, Alexander
IPC分类号： G01N27/327 , C12Q1/68
CPC分类号： C12Q1/686 , C12Q1/6837 , G01N27/3278
摘要： The present invention provides a sensor array device with multiple sensor junctions which have been created through the assembly of two or more differently functionalized surfaces. The functionalizing of the prospective sensor junction areas with sensor compounds occurred when the different surfaces were physically separated from each other before the assembly of the sensor array. By these means, sensor junctions can be built smaller than conventional deposition techniques like printing and photolithography would allow for otherwise. As a consequence, each individual sensor junction contains two potentially different sensor compounds. The sensor array identifies and quantifies different biomolecules.

2. 发明公开

EP2681544A1 BIOSENSOR ARRAY FORMED BY JUNCTIONS OF FUNCTIONALIZED ELECTRODES 失效
标题翻译： ARRAY MADE OUT节点指向官能化电极
公开(公告)号：EP2681544A1
公开(公告)日：2014-01-08
申请号：EP12707463.1
申请日：2012-02-27
申请人： Lexogen GmbH
发明人： REDA, Torsten , HAGLMÜLLER, Jakob , SCHITTER, Georg , SEITZ, Alexander
IPC分类号： G01N27/327 , C12Q1/68
CPC分类号： C12Q1/686 , C12Q1/6837 , G01N27/3278
摘要： The present invention provides a sensor array device with multiple sensor junctions which have been created through the assembly of two or more differently functionalized surfaces. The functionalizing of the prospective sensor junction areas with sensor compounds occurred when the different surfaces were physically separated from each other before the assembly of the sensor array. By these means, sensor junctions can be built smaller than conventional deposition techniques like printing and photolithography would allow for otherwise. As a consequence, each individual sensor junction contains two potentially different sensor compounds. The sensor array identifies and quantifies different biomolecules.

3. 发明授权

EP2531610B1 COMPLEXITIY REDUCTION METHOD 有权
标题翻译：完全简化法
公开(公告)号：EP2531610B1
公开(公告)日：2018-03-21
申请号：EP11702031.3
申请日：2011-02-02
申请人： Lexogen GmbH
发明人： SEITZ, Alexander , HAGLMÜLLER, Jakob , REDA, Torsten
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6855 , C12Q1/6869 , C12Q2523/301 , C12Q2537/143 , C12Q2525/191
摘要： The present invention relates to a method for the reduction of the complexity of nucleic acid pool(s), comprising €¢ providing a sample with one or more nucleic acid molecules, €¢ cutting the nucleic acid molecules by a random and/or sequence independent cutting step thereby obtaining a pool of nucleic acid fragments, €¢ amplifying one or more fragments of said nucleic acid molecules, wherein the one or more fragments constitute at least a fraction of all fragments of the nucleic acid molecules, and wherein the amplified or amplifying one or more fragments of said fraction are divided into different subpools, and wherein the fragments of each subpool comprise a common nucleic acid feature.

4. 发明公开

EP2531610A1 COMPLEXITIY REDUCTION METHOD 有权
标题翻译： KOMPLEXITÄTSREDUZIERUNGSVERFAHREN
公开(公告)号：EP2531610A1
公开(公告)日：2012-12-12
申请号：EP11702031.3
申请日：2011-02-02
申请人： Lexogen GmbH
发明人： SEITZ, Alexander , HAGLMÜLLER, Jakob , REDA, Torsten
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6855 , C12Q1/6869 , C12Q2523/301 , C12Q2537/143 , C12Q2525/191
摘要： The present invention relates to a method for the reduction of the complexity of nucleic acid pool(s), comprising €¢ providing a sample with one or more nucleic acid molecules, €¢ cutting the nucleic acid molecules by a random and/or sequence independent cutting step thereby obtaining a pool of nucleic acid fragments, €¢ amplifying one or more fragments of said nucleic acid molecules, wherein the one or more fragments constitute at least a fraction of all fragments of the nucleic acid molecules, and wherein the amplified or amplifying one or more fragments of said fraction are divided into different subpools, and wherein the fragments of each subpool comprise a common nucleic acid feature.
摘要翻译：本发明涉及降低核酸池的复杂性的方法，其包括向样品提供一种或多种核酸分子，通过随机和/或序列独立地切割核酸分子切割步骤，从而获得核酸片段池，扩增所述核酸分子的一个或多个片段，其中所述一个或多个片段构成核酸分子的所有片段的至少一部分，并且其中扩增或扩增所述级分的一个或多个片段被分成不同的子池，并且其中每个子池的片段包含共同的核酸特征。

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