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1. 发明公开

EP2278375A1 Confocal microscope for imaging of selected locations of the body of a patient 有权
标题翻译： Konfokalmikroskop zur AbbildungausgewählterStellen desKörperseines Patienten
公开(公告)号：EP2278375A1
公开(公告)日：2011-01-26
申请号：EP10013218.2
申请日：2004-05-20
申请人： LUCID, INC.
发明人： Fox, William, J. , Distasio, Christopher, C. , Grodevant, Scott, R.
IPC分类号： G02B21/00 , G02B7/00 , G02B21/36 , A61B5/103
CPC分类号： G02B21/0048 , A61B5/0064 , A61B5/0068 , A61B5/6835 , G02B21/0012 , G02B21/0028 , G02B21/008 , G02B21/362
摘要： A confocal imaging microscope, especially for the cellular imaging of the skin at selected locations, is ergonomic in use, compact, and positionable at the locations thereby providing for patient comfort during imaging. An imaging head (28) is gimble mounted on a multi-axis compound arm (34) to allow for precise placement of a confocal objective (116) extending from the head at selected locations against the skin of the patient while providing for patient comfort. The arm (34) attaches the head to an upright station (10) which may be movable along the floor on which the station is disposed. The station (10) has a platform (16) on which a keyboard (24) and a display (22) for monitoring the images is supported. The station (10) also supports a personal computer (PC) (26) for processing signals providing the images on the display and controlling the microscope.; The head (28) contains an integrated assembly of the optical and mechanical components of the microscope. The assembly includes a main chassis plate (82). The optical components are mounted principally on one side of the plate while a PC board (130) is mounted on the opposite side of the plate. The board (130) mounts the electronic components, including interfaces, a microprocessor (222), and drivers (206, 208, 210) for motors (105, 106, 108) which control scanning and may also control fine positioning of the locations being imaged. Controls (50) for the fine positioning and focusing are on the head (28) for ease of use. The head (28) is detachable from the arm for manual disposition which is useful when imaging, not only the skin but other tissues, especially for research in investigating living processes at the cellular level.
摘要翻译：共焦成像显微镜，特别是用于在选定位置的皮肤的细胞成像，其人体工程学使用，紧凑和可定位在位置，从而提供患者在成像期间的舒适度。成像头（28）被安装在多轴复合臂（34）上，以允许在选定位置处从选定位置延伸的聚焦物镜（116）精确地放置在患者皮肤上，同时提供患者舒适度。臂（34）将头部附接到直立站（10），其可沿着设置站的地板移动。站（10）具有平台（16），支撑用于监视图像的键盘（24）和显示器（22）。站（10）还支持个人计算机（PC）（26），用于处理在显示器上提供图像并控制显微镜的信号; 头部（28）包含显微镜的光学和机械部件的集成组件。组件包括主底板（82）。光学部件主要安装在板的一侧，而PC板（130）安装在板的相对侧上。板（130）安装电子部件，包括接口，微处理器（222）和用于控制扫描的电动机（105,106,108）的驱动器（206,208,210），并且还可以控制位置的精细定位成像。用于精细定位和聚焦的控制器（50）位于头部（28）上，以便于使用。头部（28）可从手臂上拆卸，用于人工处理，这对成像时不仅皮肤而且其它组织尤其适用于调查细胞水平的生活过程的研究是有用的。

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