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1. 发明公开

EP3264362A1 IMAGE PROCESSING DEVICE, IMAGE PROCESSING METHOD, AND IMAGE PROCESSING PROGRAM 无效
标题翻译：图像处理装置，图像处理方法和图像处理程序
公开(公告)号：EP3264362A1
公开(公告)日：2018-01-03
申请号：EP16755190.2
申请日：2016-02-08
申请人： Konica Minolta, Inc.
发明人： ICHITANI, Shuji
IPC分类号： G06T7/00 , G01N21/64 , G01N33/48 , G06T1/00 , G06T7/60 , G06T7/11 , G06T7/136
CPC分类号： G01N21/6458 , G01N21/64 , G01N33/48 , G06T1/00 , G06T7/00 , G06T7/0012 , G06T7/11 , G06T7/136 , G06T7/60 , G06T2207/20036 , G06T2207/20092 , G06T2207/30024 , G06T2207/30096
摘要： Provided are an image processing device, an image processing method, and an image processing program, with which a user can easily modify a portion of an image that has been created by automatic image processing. This image processing device, which is an image processing device that creates an image of interest from an image formed by photographing cells in a specimen, is characterized by being equipped with: a cell image input means for inputting the image; a setting means that sets one or more subject images within the image; a creation means that subjects each of the subject images to image processing using a prescribed parameter, and creates multiple candidate images; and a display means that displays the multiple candidate images created by the creation means.
摘要翻译：提供了一种图像处理装置，图像处理方法和图像处理程序，通过该图像处理装置，用户可以容易地修改已经通过自动图像处理创建的图像的一部分。该图像处理装置是从通过拍摄标本中的细胞而形成的图像生成关注图像的图像处理装置，其特征在于，具备：细胞图像输入单元，输入图像; 设置装置，用于设置图像内的一个或多个对象图像; 创建装置，其使用规定的参数对每个被摄体图像进行图像处理，并创建多个候选图像; 以及显示装置，显示由创建装置创建的多个候选图像。

2. 发明公开

EP3124956A1 IMAGE PROCESSING DEVICE AND IMAGE PROCESSING PROGRAM 审中-公开
标题翻译：图像处理设备和图像处理程序
公开(公告)号：EP3124956A1
公开(公告)日：2017-02-01
申请号：EP14885851.7
申请日：2014-03-27
申请人： Konica Minolta, Inc.
发明人： ICHITANI, Shuji , TOYAMA, Osamu
IPC分类号： G01N21/64
CPC分类号： G06K9/00127 , B82Y30/00 , G01N1/30 , G06K9/00134 , G06K9/0014 , G06K9/4604 , G06K9/6215 , G06T7/0012 , G06T2207/10056 , G06T2207/10061 , G06T2207/10064 , G06T2207/20212 , G06T2207/30024
摘要： An image processing device inputs a bright field image of a tissue slice in which a cell nucleus is stained and a fluorescent image of the tissue slice in which a specific biological substance is stained with a fluorescent staining reagent (S10), extracts a cell nucleus from the image of the cell nucleus (S20), extracts a fluorescent bright point from the fluorescent image (S30), specifies a cell nucleus to which the fluorescent bright point is assigned on the basis of the distance between the cell nucleus and the fluorescent bright point, and assigns the fluorescent bright point with the cell nucleus (S40).
摘要翻译：图像处理装置用荧光染色试剂输入细胞核被染色的组织切片的明视野图像和特定生物物质被染色的组织切片的荧光图像（S10），从细胞核提取细胞核细胞核的图像（S20），从荧光图像中提取荧光亮点（S30），基于细胞核与荧光亮点之间的距离来指定荧光亮点所指定的细胞核，并将荧光亮点与细胞核分配（S40）。

3. 发明授权

EP3232402B1 IMAGE PROCESSING APPARATUS AND IMAGE PROCESSING PROGRAM 有权
公开(公告)号：EP3232402B1
公开(公告)日：2020-05-06
申请号：EP15866919.2
申请日：2015-11-30
申请人： Konica Minolta, Inc.
发明人： ICHITANI, Shuji
IPC分类号： G06T7/00 , G01N33/48 , G06T1/00 , G06T7/12 , G06T7/174

4. 发明公开

EP3086110A1 IMAGE PROCESSING DEVICE, PATHOLOGICAL DIAGNOSIS SUPPORT SYSTEM, IMAGE PROCESSING PROGRAM, AND IMAGE PROCESSING METHOD 审中-公开
标题翻译：成像设备中，系统支持病理诊断，图像处理程序和图象处理
公开(公告)号：EP3086110A1
公开(公告)日：2016-10-26
申请号：EP14870827.4
申请日：2014-12-17
申请人： Konica Minolta, Inc.
发明人： WATANABE, Yasuhiro , ICHITANI, Shuji , GONDA, Kohsuke , OHUCHI, Noriaki , WATANABE, Mika
IPC分类号： G01N21/64 , G01N21/27 , G01N33/48 , G01N33/483 , G06T1/00
CPC分类号： G01N33/4833 , A61B5/0071 , G06K9/0014 , G06T5/50 , G06T7/0012 , G06T7/11 , G06T2207/10064 , G06T2207/20221 , G06T2207/30024
摘要： An image processing device (2A) comprises: an input means for inputting a brightfield image representing cell morphology in a tissue section, and a fluorescence image representing, by fluorescent bright spots, the expression of a specific protein in the same range of the tissue section; a first generation means for generating a cell image obtained by extracting a specific site of a cell from the brightfield image; a second generation means for generating an image obtained by extracting bright spot regions from the fluorescence image, creating a brightness profile for each bright spot region, and generating a fluorescent particle image obtained by extracting the fluorescent particles in the bright spot regions on the basis of the fluorescence profile for one fluorescent particle, which serves as a fluorescence bright spot source; and a calculation means for superimposing the cell image and the fluorescent particle image on one another.
摘要翻译：一种图像处理装置（2A）包括：输入装置，用于输入表示在组织切片的细胞形态亮场图像和荧光图像表示，通过荧光亮点，特定蛋白的在相同范围内的组织切片中的表达 ; 第一产生装置，用于产生通过提取来自亮场图像的细胞的特定部位获得的细胞图像; 第二产生装置，用于通过从所述荧光图像中提取的亮点区域而获得的图像，从而为每个亮点区域亮度分布，并生成由的基础上提取中的亮点区域的荧光发色粒子获得的荧光颗粒图像为一个荧光体粒子，其用作一个亮点荧光源的荧光谱; 以及计算装置，用于叠加所述细胞图像和在彼此的荧光颗粒图像。

5. 发明授权

EP3124956B1 IMAGE PROCESSING DEVICE AND IMAGE PROCESSING PROGRAM 审中-公开
公开(公告)号：EP3124956B1
公开(公告)日：2018-12-26
申请号：EP14885851.7
申请日：2014-03-27
申请人： Konica Minolta, Inc.
发明人： ICHITANI, Shuji , TOYAMA, Osamu
IPC分类号： G01N21/64 , G06T7/00 , G06K9/62 , G06K9/00 , G01N1/30 , B82Y30/00
CPC分类号： G06K9/00127 , B82Y30/00 , G01N1/30 , G06K9/00134 , G06K9/0014 , G06K9/4604 , G06K9/6215 , G06T7/0012 , G06T2207/10056 , G06T2207/10061 , G06T2207/10064 , G06T2207/20212 , G06T2207/30024
摘要： An image processing device inputs a bright field image of a tissue slice in which a cell nucleus is stained and a fluorescent image of the tissue slice in which a specific biological substance is stained with a fluorescent staining reagent (S10), extracts a cell nucleus from the image of the cell nucleus (S20), extracts a fluorescent bright point from the fluorescent image (S30), specifies a cell nucleus to which the fluorescent bright point is assigned on the basis of the distance between the cell nucleus and the fluorescent bright point, and assigns the fluorescent bright point with the cell nucleus (S40).

6. 发明公开

EP3232402A1 IMAGE PROCESSING APPARATUS AND IMAGE PROCESSING PROGRAM 有权
标题翻译：图像处理装置和图像处理程序
公开(公告)号：EP3232402A1
公开(公告)日：2017-10-18
申请号：EP15866919.2
申请日：2015-11-30
申请人： Konica Minolta, Inc.
发明人： ICHITANI, Shuji
IPC分类号： G06T7/00 , G01N33/48 , G06T1/00
摘要： The present invention provides an image processing apparatus and an image processing program with which it is possible to automatically extract a cell area of interest without increasing the number of conventional steps of pathological diagnosis. This image processing apparatus 2A is characterized in being provided with: an input means for inputting a fluorescent image in which fluorescent bright spots represent the expression of a specific biological substance in a sample in which the biological substance appearing in a first structure of a cell is dyed using a fluorescent substance, and a morphological image in which the morphology of a second structure of the cell in the sample is represented, the morphological image including the same range as the fluorescent image; a feature amount extraction means for extracting the feature amount of the second structure from the morphological image; a bright-spot extraction means for extracting the fluorescent bright spots from the fluorescent image; and an area-of-interest determination means for determining an area of interest on the basis of the feature amount of the second structure and the distribution of the fluorescent bright spots.
摘要翻译：本发明提供一种图像处理装置和图像处理程序，利用该图像处理装置和图像处理程序可以自动提取感兴趣的细胞区域而不增加传统的病理诊断步骤的数量。该图像处理装置2A的特征在于具有：输入装置，用于输入荧光图像，其中荧光亮点表示在出现在细胞的第一结构中的生物物质是样品中的特定生物物质的表达使用荧光物质染色的形态图像和表示样品中的细胞的第二结构的形态的形态图像，所述形态图像包括与荧光图像相同的范围; 特征量提取装置，用于从形态图像中提取第二结构的特征量; 用于从荧光图像中提取荧光亮点的亮点提取装置; 以及感兴趣区域确定装置，用于基于第二结构的特征量和荧光亮点的分布来确定感兴趣区域。

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