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1. 发明公开

EP2844324A1 A NEW METHOD AND APPARATUS TO ATTAIN AND MAINTAIN TARGET ARTERIAL BLOOD GAS CONCENTRATIONS USING RAMP SEQUENCES 有权转让
标题翻译：用RAMP序列获得和维持目标动脉血气浓度的新方法和装置
公开(公告)号：EP2844324A1
公开(公告)日：2015-03-11
申请号：EP13784953.5
申请日：2013-04-30
申请人： Klein, Michael , Fisher, Joseph , Duffin, James , Slessarev, Marat , Kessler, Cathie , Ito, Shoji , Sobczyk, Olivia , Battisti-Charbonney, Anne , Mikulis, David , Mandell, Daniel Michael
发明人： Klein, Michael , Fisher, Joseph , Duffin, James , Slessarev, Marat , Kessler, Cathie , Ito, Shoji , Sobczyk, Olivia , Battisti-Charbonney, Anne , Mikulis, David , Mandell, Daniel Michael
IPC分类号： A61M16/00 , A61B5/021 , A61B5/08 , A61B5/091 , A61M16/06
CPC分类号： A61M16/0066 , A61B5/082 , A61B5/091 , A61M16/0045 , A61M16/026 , A61M16/1005 , A61M16/12 , A61M16/122 , A61M2016/0027 , A61M2016/0036 , A61M2016/1025 , A61M2016/103 , A61M2202/0208 , A61M2202/0225 , A61M2205/3303 , A61M2205/502 , A61M2205/52 , A61M2230/04 , A61M2230/202 , A61M2230/205 , A61M2230/208 , A61M2230/432 , A61M2230/435
摘要： An apparatus and method for controlling the end tidal partial pressure of a gas X in a subject's lung, and to the use of such an apparatus and method for research, diagnostic and therapeutic purposes, wherein the method consists of: - obtaining input of a series of logistically attainable PetX values for a series of respective breaths: - determining an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX for each of said respective breaths: and - controlling a gas delivery device to deliver the amount of gas in a volume of gas delivered to the subject in each of said respective breaths to target the respective PetX for that breath.
摘要翻译：一种用于控制受检者肺中气体X的末端潮气分压的装置和方法以及这种装置和方法用于研究，诊断和治疗目的的用途，其中该方法包括： - 获得一系列的输入在一系列相应呼吸中可以在物理上可达到的PetX值中： - 确定吸入气体中受试者吸入的气体量X，以针对所述各个呼吸中的每一个呼吸目标PetX：和 - 控制气体输送装置递送在每次所述各呼吸中递送至对象的气体量中的气体量以针对该呼吸针对相应PetX。

2. 发明公开

EP2788063A1 AN APPARATUS TO ATTAIN AND MAINTAIN TARGET END TIDAL PARTIAL PRESSURE OF A GAS 有权转让
标题翻译： DEVICE成就和保全潮汐SOLLPARTIALDRUCKES气体
公开(公告)号：EP2788063A1
公开(公告)日：2014-10-15
申请号：EP12856262.6
申请日：2012-12-05
申请人： Klein, Michael , Fisher, Joseph , Duffin, James , Slessarev, Marat , Kessler, Cathie , Ito, Shoji
发明人： Klein, Michael , Fisher, Joseph , Duffin, James , Slessarev, Marat , Kessler, Cathie , Ito, Shoji
IPC分类号： A61M16/10 , A61B5/08
CPC分类号： A61M16/0051 , A61B5/083 , A61B5/0833 , A61B5/0836 , A61B5/4836 , A61M16/0003 , A61M16/0069 , A61M16/026 , A61M16/085 , A61M16/0883 , A61M16/1005 , A61M16/12 , A61M16/122 , A61M2016/0021 , A61M2016/0027 , A61M2016/102 , A61M2016/1025 , A61M2016/103 , A61M2205/502 , A61M2230/43 , A61M2230/432 , A61M2230/435
摘要： A processor obtains input of a logistically attainable end tidal partial pressure of gas X (PetX[i]T) for one or more respective breaths [i] and input of a prospective computation of an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX[i]T for a respective breath [i] using inputs required to utilize a mass balance relationship, wherein one or more values required to control the amount of gas X in a volume of gas delivered to the subject is output from an expression of the mass balance relationship. The mass balance relationship is expressed in a form which takes into account (prospectively), for a respective breath [i], the amount of gas X in the capillaries surrounding the alveoli and the amount of gas X in the alveoli, optionally based on a model of the lung which accounts for those sub-volumes of gas in the lung which substantially affect the alveolar gas X concentration affecting mass transfer.

3. 发明公开

EP2571422A1 NON-INVASIVE CARDIAC OUTPUT DETERMINATION 有权转让
标题翻译： NICHTINVASIVE BESTIMMUNG DES HERZMINUTENVOLUMENS
公开(公告)号：EP2571422A1
公开(公告)日：2013-03-27
申请号：EP11782808.7
申请日：2011-05-18
申请人： Fisher, Joseph , Klein, Michael , Duffin, James
发明人： Fisher, Joseph , Klein, Michael , Duffin, James
IPC分类号： A61B5/08 , A61B5/026 , G06F19/00
CPC分类号： A61B5/0205 , A61B5/026 , A61B5/029 , A61B5/0813 , A61B5/0836 , A61B5/7225 , A61B5/7278 , A61M16/0057 , A61M16/12
摘要： A method of controlling a gas delivery apparatus including an apparatus controllable variable using an iterative algorithm to deliver a test gas (TG) for non- invasively determining a subject's pulmonary blood flow comprising iteratively generating and evaluating test values of a iterated variable based on an iterative algorithm in order output a test value of the iterated variable that meets a testcriterion wherein iterative algorithm is characterized in that it defines a test mathematical relationship between the at least one apparatus controllable variable, the iterated variable and an end tidal concentration of test gas attained by setting the apparatus controllable variable, such that the iterative algorithm is determinative of whether iteration on the test value satisfies a test criterion or iteratively generates a progressively refined test value.
摘要翻译：一种使用迭代算法来控制气体输送装置的方法，所述装置可控变量使用迭代算法递送用于非侵入性地确定受试者的肺血流的测试气体（TG），包括迭代生成并评估迭代变量的测试值算法，以输出满足测试标准的迭代变量的测试值，其中迭代算法的特征在于其定义了至少一个设备可控变量，迭代变量和获得的测试气体的终端潮汐浓度之间的测试数学关系通过设置装置可控变量，使得迭代算法确定测试值上的迭代是否满足测试标准或迭代地生成逐渐改进的测试值。

4. 发明公开

EP3003446A1 CONTROLLING ARTERIAL BLOOD GAS CONCENTRATION 审中-公开
标题翻译：控制动脉血气体浓度
公开(公告)号：EP3003446A1
公开(公告)日：2016-04-13
申请号：EP14806925.5
申请日：2014-06-03
申请人： Klein, Michael , Fisher, Joseph
发明人： Klein, Michael , Fisher, Joseph
IPC分类号： A61M16/10 , A61B5/08 , A61M16/00
CPC分类号： A61B5/0836 , A61B5/0833 , A61M16/0045 , A61M16/0078 , A61M16/026 , A61M16/0891 , A61M16/104 , A61M16/12 , A61M16/125 , A61M16/208 , A61M2016/0027 , A61M2016/0036 , A61M2016/0039 , A61M2202/0208 , A61M2202/0225 , A61M2202/0241 , A61M2205/057 , A61M2230/43 , A61M2230/432 , A61M2230/435 , A61M2230/437
摘要： A system for controlling an amount of at least one gas X in a subject's lung to target at least one end tidal partial pressure of at least one gas X (PetX
T ), the system uses a control system for controlling the gas delivery device, wherein the control system implements a sequential gas delivery system and a feedback algorithm which compares a PetX
T for a respective breath [i] of variable size and preferably a respective current PetX value measured by a measurement system, to obtain an error signal, the feedback algorithm adapted for generating a control signal based on the error signal, the control signal determining the amount of gas X to be inspired by the subject in at least a first portion of a respective ensuing respective inspiratory cycle to target PetX
T for the respective interval.

5. 发明公开

EP2827932A1 VIRTUAL RESPIRATORY GAS DELIVERY SYSTEMS AND CIRCUITS 有权转让
标题翻译：虚拟呼吸气体发行系统和电路
公开(公告)号：EP2827932A1
公开(公告)日：2015-01-28
申请号：EP13764140.3
申请日：2013-03-19
申请人： Klein, Michael , Fisher, Joseph
发明人： Klein, Michael , Fisher, Joseph
IPC分类号： A61M16/10 , A61B5/08 , A61B5/087
摘要： A respiratory gas delivery system monitors gas flow over the course of a breath in real time and uses this parameter to simulate, in whole or part, the function of a reference respiratory gas delivery system, in particular structural features, particularly structural components of parts of the reference system, to overcome a structural limitation of the reference system.

6. 发明公开

EP3137704A1 BEFESTIGUNGSSYSTEM FÜR GEBÄUDEFASSADEN UND SEINE VERWENDUNG 有权转让
标题翻译： BEFESTIGUNGSSYSTEMFÜRGEBÄUDEFASSADENUND SEINE VERWENDUNG
公开(公告)号：EP3137704A1
公开(公告)日：2017-03-08
申请号：EP15733606.6
申请日：2015-04-21
申请人： Klein, Michael
发明人： Klein, Michael
IPC分类号： E04F13/08
CPC分类号： E04F13/083 , E04F13/0891
摘要： The invention relates to an attachment fitting (1) and to a grid support (2) of a modular fastening system for building facade panels (9). The attachment fitting (1) has at least one connecting element (4) that can be connected to a connecting receptacle, the shape of which corresponds to the connection element (4), on the rear side of the facade panel (9). The height (H) of the attachment fitting is smaller than the modular vertical grid (M) of the façade system, wherein the attachment fitting (1) can be brought into engagement with the grid support (2) in a form-fitting manner, which grid support (2) has a regular longitudinal grid. The invention makes it possible to replace traditional rail systems, which have to be manufactured in a project-specific manner, with a modular system of attachment fittings (1) which are positioned on standardized grid supports (2) without additional fastening elements. Any facade layouts can be realized, including mixed grids and panel blanks, without the need for prefabrication of elements for the facade substructure, in particular project-specific support rails. Material savings and quality and safety improvements at the construction site are achieved, and existing rail-length restrictions no longer apply. The risk for the builder is reduced, since no project-related prefabrication of rail systems and no additional delivery of specific individual parts are required.
摘要翻译：本发明涉及用于建筑立面板（9）的模块化紧固系统的附接配件（1）和网格支撑件（2）。连接配件（1）具有至少一个连接元件（4），该连接元件可连接到在立面板（9）的后侧上与连接元件（4）相对应的连接插座。安装配件的高度（H）小于外墙系统的模块化垂直格栅（M），其中附件配件（1）可以以格式配合方式与网格支撑件（2）接合，哪个网格支撑（2）具有规则的纵向网格。本发明使得可以用必须以特定项目的方式制造的传统轨道系统与安装配件（1）的模块化系统进行替换，所述连接配件（1）定位在标准化的格栅支撑件（2）上，而没有附加的紧固元件。可以实现任何外观布局，包括混合网格和面板坯料，而不需要为立面底层结构，特别是项目特定的支撑轨道预制元件。实现了施工现场的物料节约和质量和安全改进，现有的铁路限制不再适用。减少建筑工人的风险，因为不需要与项目相关的铁路系统预制和不需要特定的单独零件的额外交付。

7. 发明公开

EP0720451A1 TEMPERATURE GAUGE FOR SURGICAL DRILLS AND METHOD EMPLOYING SAME 失效
标题翻译：温度计其应用的外科钻子和方法
公开(公告)号：EP0720451A1
公开(公告)日：1996-07-10
申请号：EP94930459.0
申请日：1994-09-20
申请人： Klein, Michael , Yacker, Miles J.
发明人： Klein, Michael , Yacker, Miles J.
IPC分类号： A61C1 , A61C3 , A61C8 , A61C19 , A61B17
CPC分类号： B23Q17/0985 , A61B17/16 , A61B2017/00084 , A61C1/00 , A61C8/0089 , A61C19/04 , Y10T408/05 , Y10T408/21
摘要： This invention is a temperature gauge (30) for surgical drills (15) of the type having a surgical head (18) to which a drill bur (20) having a throughbore extending to its drill bur tip is removably mounted, and includes a temperature sensor (36) receivable in the drill bur throughbore for sensing and measuring the temperature at the drill bur tip and a thermometer (31) coupled to the temperature sensor (36) for displaying the temperature at the drill bur tip. A method of measuring the temperature of the drill site in the bone of a patient is also disclosed.

8. 发明公开

EP1030598A1 SURGICAL TEMPLATE ASSEMBLY AND METHOD FOR DRILLING AND INSTALLINGDENTAL IMPLANTS 审中-公开
标题翻译：口罩及方法牙种植体钻PLACE
公开(公告)号：EP1030598A1
公开(公告)日：2000-08-30
申请号：EP98960513.4
申请日：1998-11-23
申请人： Klein, Michael , Abrams, Michael E. , Manno, Richard J.
发明人： Klein, Michael , Abrams, Michael E. , Manno, Richard J.
IPC分类号： A61B6/14 , A61C8/00
CPC分类号： A61C8/0089 , A61C1/084 , A61C9/0053 , A61C2201/005
摘要： The present invention is a surgical template and method for drilling osteotomies (e.g., holes in a jaw bone), and installing one or more dental implants (170) using a surgical template assembly (10). The surgical template assembly (10) is provided with one or more drill guides (120, 130), and one or more dental implant guides (140). The guides are positioned in the template assembly (10) by a computer driven milling machine (60) interfaced with a computer generated image of a patient's jaw bone, and a computer generated simulation of at least one dental implant so that when the template (100) is placed in the patient's mouth a trajectory of the guides in the template (100) into the patient's jawbone corresponds to a trajectory of the computer generated simulation of the dental implant (170) into the computer generated image of the patient's jawbone. Preferably, three fiducial markers (70) provide positional coordination between the CT scan data, the computer generated simulation of the dental implant, and the computer driven milling machine (60).

9. 发明公开

EP4310288A1 ELEKTRISCH BETRIEBENER KLAPPENBESCHLAG 审中-公开
公开(公告)号：EP4310288A1
公开(公告)日：2024-01-24
申请号：EP23166768.4
申请日：2023-04-05
申请人： Klein, Michael
发明人： Klein, Michael
IPC分类号： E05F15/41 , E05F15/42 , E05F15/43 , E05F15/605
摘要： Elektrisch betriebener Klappenbeschlag (1, 20, 30) für ein Möbelelement, insbesondere eine Kücheneinheit (100) mit einer Klappe (16) mit zueinander verschwenkbaren Klappenabschnitten (16A, 16B), einer Antriebseinheit (60) zum Bewegen der Klappe (16) zwischen einer angehobenen und einer abgesenkten Endposition, um eine Fläche des Möbelelements (100) in der abgesenkten Endposition zu bedecken, eine Steuervorrichtung (3) zum Steuern der Antriebseinheit (60), und eine mit der Steuervorrichtung (3) kommunikativ verbundene Detektionseinheit (80; 81 - 83), die ausgebildet ist, ein sich in einer Bewegungsbahn (18) der Klappe (16) befindliches Objekt zu detektieren, wobei die Steuervorrichtung (3) ausgebildet ist, auf Basis eines von der Detektionseinheit (80; 81 - 83) erhaltenen Detektionssignals die Bewegung der Klappe (16) zwischen der angehobenen Endposition und der abgesenkten Endposition zu stoppen.
Es werden des Weiteren ein entsprechendes Verfahren zum Betreiben eines elektrisch betriebenen Klappenbeschlags (1, 20, 30) und ein Speichermedium mit Befehlen zum Ausführen des Verfahrens beschrieben.

10. 发明公开

EP2696927A1 GAS DELIVERY METHOD AND APPARATUS 有权转让
标题翻译：气体供给方法和装置
公开(公告)号：EP2696927A1
公开(公告)日：2014-02-19
申请号：EP12772038.1
申请日：2012-04-12
申请人： Klein, Michael
发明人： Klein, Michael
IPC分类号： A61M16/12 , A61M16/10 , B01F3/02 , C01B31/20
CPC分类号： A61M16/12 , A61M16/0051 , A61M16/026 , A61M16/20 , A61M16/203 , A61M2016/0036 , A61M2016/0039 , A61M2016/102 , A61M2016/103 , A61M2202/0225 , A61M2205/18 , A61M2205/3334 , A61M2205/50 , A61M2205/502 , A61M2230/432 , G05D11/138
摘要： An apparatus, method and system for delivering CO2 into an inspiratory gas stream to formulate a blended respiratory gas in a manner that continuously maintains a target CO2 concentration in a volume of the inspired respiratory gas, for example, over the course of a breath or a volumetrically definable part thereof or a series of partial or full breaths.

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