专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP3569248A1 COGNITIVE FUNCTION IMPROVING AGENT 有权
公开(公告)号：EP3569248A1
公开(公告)日：2019-11-20
申请号：EP17886842.8
申请日：2017-12-26
申请人： Kao Corporation
发明人： OKAHARA, Fumiaki , KOGA, Yoshitaka , MORI, Takuya
IPC分类号： A61K45/00 , A61K31/16 , A61K31/166 , A61K31/20 , A61K31/22 , A61K31/31 , A61K31/404 , A61K31/519 , A61K31/683 , A61K31/685 , A61K31/717 , A61K31/718 , A61K31/722 , A61K31/734 , A61K31/785 , A61K36/73 , A61K36/899 , A61K39/395 , A61P25/28 , C07K16/26 , G01N33/15
摘要： Provided are a cognitive function improving agent effective for improving cognitive function such as memory and learning ability, and a method for evaluating or selecting the cognitive function improving agent. The cognitive function improving agent comprises a GIP function inhibitor as an active ingredient.

2. 发明公开

EP3124966A1 METHOD FOR EVALUATING OR SELECTING GIP RISE INHIBITOR 有权转让
标题翻译： VERFAHREN ZUR BEURTEILUNG ODER AUSWAHL VON EINES GIP-ANSTIEGSHEMMERS
公开(公告)号：EP3124966A1
公开(公告)日：2017-02-01
申请号：EP15769760.8
申请日：2015-03-06
申请人： Kao Corporation
发明人： KOGA, Yoshitaka , OSAKI, Noriko , WATANABE, Manabu
IPC分类号： G01N33/15 , C12Q1/02 , C12Q1/68 , G01N33/50 , G01N33/68
CPC分类号： G01N33/5023 , C12Q1/68 , G01N33/92 , G01N2500/10 , G01N2800/042
摘要： A method for evaluating or selecting an agent for suppressing GIP level elevation, comprising the following steps (A) to (D): (A) contacting a test substance with a mammal-derived tissue or cell capable of expressing an FABP4 gene or FABP5 gene, or an FABP4 protein or FABP5 protein; (B) measuring an expression level of the FABP4 gene or FABP5 gene, an expression level of the FABP4 protein or FABP5 protein, or an activity of the FABP4 protein or FABP5 protein in the mammal-derived tissue or cell; (C) comparing the expression level or activity measured in the above (B) with an expression level of an FABP4 gene or FABP5 gene, an expression level of an FABP4 protein or FABP5 protein, or an activity of an FABP4 protein or FABP5 protein in a control group; and (D) evaluating or selecting a test substance which reduces the expression level of the FABP4 gene or FABP5 gene, the expression level of the FABP4 protein or FABP5 protein, or the activity of the FABP4 protein or FABP5 protein as an agent suppressing GIP level elevation based on results of the above (C).
摘要翻译：一种用于评估或选择抑制GIP水平升高的药剂的方法，包括以下步骤（A）至（D）：（A）使测试物质与能够表达FABP4基因或FABP5基因的哺乳动物衍生的组织或细胞接触，或FABP4蛋白或FABP5蛋白; （B）测量FABP4基因或FABP5基因的表达水平，FABP4蛋白或FABP5蛋白的表达水平，或哺乳动物衍生的组织或细胞中FABP4蛋白或FABP5蛋白的活性; （C）将上述（B）中测量的表达水平或活性与FABP4基因或FABP5基因的表达水平，FABP4蛋白或FABP5蛋白的表达水平或FABP4蛋白或FABP5蛋白的活性进行比较一个对照组; 和（D）评估或选择降低FABP4基因或FABP5基因的表达水平，FABP4蛋白或FABP5蛋白的表达水平或FABP4蛋白或FABP5蛋白作为抑制GIP水平的药剂的活性的测试物质基于上述（C）的结果提升。

3. 发明公开

EP3797763A1 GIP ELEVATION INHIBITOR 审中-公开
公开(公告)号：EP3797763A1
公开(公告)日：2021-03-31
申请号：EP19806677.1
申请日：2019-05-22
申请人： Kao Corporation
发明人： TAKAMURA, Akihiro , KOGA, Yoshitaka , HASHIZUME, Kohjiro , MORI, Takuya
IPC分类号： A61K31/047 , A23L33/125 , A61P1/00 , A61P1/14 , A61P3/02 , A61P3/04 , A61P5/00
摘要： Provided is a GIP elevation inhibitor useful as, e.g., a pharmaceutical product and food. The GIP elevation inhibitor comprises mannitol as an active ingredient.

4. 发明公开

EP3733169A1 COGNITIVE FUNCTION IMPROVEMENT AGENT 审中-公开
公开(公告)号：EP3733169A1
公开(公告)日：2020-11-04
申请号：EP18897701.1
申请日：2018-12-20
申请人： Kao Corporation
发明人： OKAHARA, Fumiaki , KOGA, Yoshitaka , YANO, Michiko , ISHIDA, Keiko , MORI, Takuya , MISAWA, Koichi
IPC分类号： A61K31/047 , A23L33/10 , A23L33/125 , A61K36/07 , A61P25/28
摘要： To provide an agent for improving a cognitive function effective for improving a cognitive function such as memory and learning ability. An agent for improving a cognitive function, comprising mannitol/a squeeze or an extract of Agaricus bisporus as an active ingredient.

5. 发明公开

EP3560515A1 MOTOR CONTROL FUNCTION IMPROVING AGENT 有权
公开(公告)号：EP3560515A1
公开(公告)日：2019-10-30
申请号：EP17888377.3
申请日：2017-12-26
申请人： Kao Corporation
发明人： OKAHARA, Fumiaki , KOGA, Yoshitaka , MORI, Takuya
IPC分类号： A61K45/00 , A61K31/16 , A61K31/4045 , A61K39/395 , A61P19/00 , A61P21/00 , A61P25/00 , G01N33/15 , G01N33/50
摘要： Provided are a motor control function improving agent for improving a motor control function decreased by aging or tiredness and a method for evaluating or selecting the motor control function improving agent. The motor control function improving agent comprises a GIP function inhibitor as an active ingredient.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式