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1. 发明公开

EP2557938A4 PROTECTED ALPHA-AMYLASE 有权转让
标题翻译： GESCHÜTZTEALPHA-AMYLASE
公开(公告)号：EP2557938A4
公开(公告)日：2013-11-20
申请号：EP11856630
申请日：2011-01-17
申请人： KEMIN IND INC
发明人： DUAN ZHIYONG , LIU YONGCAI , LAO YE , CHEN DONG , MA JUN
IPC分类号： A23K1/165 , A23K1/00 , A23K1/18
CPC分类号： A23K50/60 , A23K20/189 , A23K40/30 , A23K50/30 , A23K50/75
摘要： A protected α-amylase is described. Pelletization and encapsulation technology, in which slow-release materials and pH-sensitive materials are used to protect the α-amylase from inactivation at low pH. The protected α-amylase was found to be highly stable after as long as 3-hour treatment in acid (pH 3.0). When treated in pH 3.0 for 1 hour and followed by treatment with lipase and pancreatin in pH 7.0 for 2 hour to simulate in vivo environment, it was found that α-amylase was fully released and measurable. In addition, the protected α-amylase showed superior efficacy to the unprotected α-amylase. The protected α-amylase also demonstrated enhanced thermostability.
摘要翻译：描述了被保护的α-淀粉酶。造粒和封装技术，其中使用缓释材料和pH敏感材料来保护α-淀粉酶在低pH下失活。在酸（pH 3.0）中处理3小时后，发现被保护的α-淀粉酶高度稳定。当在pH 3.0中处理1小时，然后用pH 7.0的脂肪酶和胰酶处理2小时以模拟体内环境时，发现α-淀粉酶完全释放并且可测量。另外，受保护的α-淀粉酶显示出对未受保护的α-淀粉酶更优异的功效。受保护的α-淀粉酶也表现出增强的热稳定性。

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