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1. 发明授权

EP1942834B1 SELBSTEXPANDIERBARES MEDIZINISCHES INSTRUMENT ZUR BEHANDLUNG VON DEFEKTEN AM HERZEN EINES PATIENTEN 有权
标题翻译： SELBSTEXPANDIERBARES医疗器械治疗残破的心病人
公开(公告)号：EP1942834B1
公开(公告)日：2013-01-16
申请号：EP06806665.3
申请日：2006-11-02
申请人： JenaValve Technology Inc.
发明人： FIGULLA, Hans-Reiner , FERRARI, Markus
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2002/9528 , A61F2230/0078 , A61F2230/008

2. 发明授权

EP1940321B1 VORRICHTUNG ZUR IMPLANTATION UND BEFESTIGUNG VON HERZKLAPPENPROTHESEN 有权
标题翻译：装置植入和固定人工心脏瓣膜的
公开(公告)号：EP1940321B1
公开(公告)日：2010-12-15
申请号：EP06828826.5
申请日：2006-10-17
申请人： JenaValve Technology Inc.
发明人： FERRARI, Markus , FIGULLA, Hans-Reiner , DAMM, Christoph
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2427 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/82 , A61F2/95 , A61F2/958 , A61F2002/9528 , A61F2210/0014 , A61F2220/0025 , A61F2230/0054 , A61F2250/006
摘要： The invention relates to a device for the transvascular implantation and fastening of heart valve prostheses. Said device comprises a self-expanding heart valve stent (10) which can be inserted into a patient's aorta and is provided with a heart valve prosthesis (11) at the proximal end thereof. The aim of the invention is to optimize such a device in such a way that the heart valve prosthesis (11) can be implanted in a patient by means of a minimally invasive intervention, especially ensuring greater accuracy with which the prosthesis (11) is positioned on the patient's ventricle. Said aim is achieved by providing the inventive device with a self-expanding positional stent (20) in addition to the self-expanding heart valve stent (10). Said positional stent (20) can be inserted all the way to an aortic valve position of a patient while being embodied separately from the heart valve stent (10). The positional stent (20) and the heart valve stent (10) are configured so as to cooperate in the expanded states thereof in such a way that the positional stent (20) helps retain the heart valve stent (10) in the patient's aorta in a position relative to the heart valve which can be predefined by the positional stent (20).

3. 发明公开

EP2155115A1 MEDICAL DEVICE FOR TREATING A HEART VALVE INSUFFICIENCY OR STENOSIS 有权转让
标题翻译：医疗设备，治疗心脏瓣膜功能不全或狭窄
公开(公告)号：EP2155115A1
公开(公告)日：2010-02-24
申请号：EP07821482.2
申请日：2007-10-17
申请人： Jenavalve Technology INC.
发明人： JUNG, Johannes , STRAUBINGER, Helmut , FERRARI, Markus , FIGULLA, Hans Reiner , GUYENOT, Volker , PESCHEL, Thomas , DAMM, Christoph
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2220/0016 , A61F2230/0054
摘要： The present application relates to a self expandable endoprosthesis for treating a heart valve insufficiency. In order to provide a self -expandable heart valve stent which can be introduced into a patient's body with minimal invasion for positioning and securing a heart valve prosthesis, for example, in the aorta of a patient, the inventive endoprosthesis comprises at least one retaining means (55) for manoeuvring the endoprosthesis into and out of position within the patient.

4. 发明公开

EP1942834A1 SELBSTEXPANDIERBARES MEDIZINISCHES INSTRUMENT ZUR BEHANDLUNG VON DEFEKTEN AM HERZEN EINES PATIENTEN 有权
标题翻译： SELBSTEXPANDIERBARES医疗器械治疗残破的心病人
公开(公告)号：EP1942834A1
公开(公告)日：2008-07-16
申请号：EP06806665.3
申请日：2006-11-02
申请人： JenaValve Technology Inc.
发明人： FIGULLA, Hans-Reiner , FERRARI, Markus
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2002/9528 , A61F2230/0078 , A61F2230/008
摘要： The invention relates to a self-expandable medical instrument (100) for treatment of defects on a patient’s heart, in particular for vascular implantation of a heart-valve prosthesis (30), which medical instrument (100) can be introduced into a patient’s body by a minimally invasive approach using a catheter system (40) and comprises a stent (1) made up of a flexible lattice (2) of thin wires or filaments (2’). To ensure that the medical instrument (100) can be positioned as accurately as possible in the patient’s heart and can be safely secured there, provision is made that, in the expanded state of the medical instrument (100), the stent (1) made up of the flexible lattice (2) comprises a distal retention area (10) with a laterally outwardly protruding bead portion (12) that can be brought into engagement with at least one pocket (51) of the defective heart valve (50) of the patient, and also comprises a proximal retention area (20) and, between the distal and proximal retention areas (10, 20), a middle area (15).

5. 发明授权

EP2155115B1 MEDICAL DEVICE FOR TREATING A HEART VALVE INSUFFICIENCY OR STENOSIS 有权转让
公开(公告)号：EP2155115B1
公开(公告)日：2018-09-05
申请号：EP07821482.2
申请日：2007-10-17
申请人： JenaValve Technology, Inc.
发明人： JUNG, Johannes , STRAUBINGER, Helmut , FERRARI, Markus , FIGULLA, Hans Reiner , GUYENOT, Volker , PESCHEL, Thomas , DAMM, Christoph
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2220/0016 , A61F2230/0054
摘要： The present application relates to a self expandable endoprosthesis for treating a heart valve insufficiency. In order to provide a self -expandable heart valve stent which can be introduced into a patient's body with minimal invasion for positioning and securing a heart valve prosthesis, for example, in the aorta of a patient, the inventive endoprosthesis comprises at least one retaining means (55) for manoeuvring the endoprosthesis into and out of position within the patient.

6. 发明授权

EP1848375B1 KATHETER FÜR DIE TRANSVASKULÄRE IMPLANTATION VON HERZKLAPPENPROTHESEN 有权转让
标题翻译：导管经血管植入人工心脏瓣膜的
公开(公告)号：EP1848375B1
公开(公告)日：2013-11-06
申请号：EP06705795.0
申请日：2006-01-12
申请人： JenaValve Technology, Inc.
发明人： OTTMA, Rüdiger , MOSZNER, Robert , DAMM, Christoph , FIGULLA, Hans-Reiner , FERRARI, Markus
IPC分类号： A61F2/24 , A61F2/95
CPC分类号： A61F2/2427 , A61F2/2418 , A61F2/2436 , A61F2002/9517 , A61F2240/008

7. 发明授权

EP1259193B1 VERANKERUNG FÜR IMPLANTIERBARE HERZKLAPPENPROTHESEN 有权
标题翻译：锚植入人工心脏瓣膜
公开(公告)号：EP1259193B1
公开(公告)日：2010-11-17
申请号：EP01916903.6
申请日：2001-02-28
申请人： JenaValve Technology Inc.
发明人： FERRARI, Markus , LANG, Klaus , FIGULLA, Hans-Reiner , DAMM, Christoph , WEBER, Carsten , RISSE, Stefan , GUYENOT, Volker , MOHAUPT, Matthias , HARNISCH, Gerd , DÖRRER, Peggy
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2220/0008 , A61F2220/0016
摘要： The invention relates to an anchoring system for heart valve prostheses which can be implanted without the need for any major surgical invention by introduction via the aorta. The inventive heart valve prosthesis is designed in such a way that it can be quickly and safely brought to the aorta and fixed there. Hook-type elements are therefore secured to commissures of the heart valve prosthesis. The hooks are guided in an outward direction through the heart valve prosthesis material.

8. 发明公开

EP2244668A1 MEDICAL APPARATUS FOR THE THERAPEUTIC TREATMENT OF AN INSUFFICIENT CARDIAC VALVE 审中-公开
标题翻译：医疗设备，心脏瓣膜功能不全治疗
公开(公告)号：EP2244668A1
公开(公告)日：2010-11-03
申请号：EP09704299.8
申请日：2009-01-23
申请人： JenaValve Technology Inc.
发明人： FERRARI, Markus , FIGULLA, Hans-Reiner
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2475 , A61F2/848 , A61F2002/825 , A61F2220/0008 , A61F2220/0016 , A61F2230/0054 , A61F2250/0062
摘要： The present invention relates to a medical apparatus for the therapeutic treatment of an insufficient cardiac valve (3a, 3b). The aim of the present invention is to specify a medical apparatus which enables the therapeutic treatment of an insufficient cardiac valve, such as, for example, the mitral valve (3a) or the tricuspid valve (3b), which is arranged be- t w e e n a ventricle (1a, 1b) and an atrium (2a, 2b) of the heart, in a manner as simple as possible and as gentle as possible for the patient in a minimally invasive intervention. For this purpose, the medical apparatus according to the present invention comprises at least one valve means (10) which is designed to prevent in the implanted condition of the medical apparatus a systolic venous reflex return of blood from the atrium (2a, 2b) of the heart into at least one vein (4a, 4a', 4b, 4b', 4c, 4c') which belongs to a venous system (4) which leads into the atrium (2a, 2b) of the heart.

9. 发明授权

EP1259195B1 VORRICHTUNG ZUR BEFESTIGUNG UND VERANKERUNG VON HERZKLAPPENPROTHESEN 有权
标题翻译：装置用于固定和锚人工心脏瓣膜的
公开(公告)号：EP1259195B1
公开(公告)日：2008-10-15
申请号：EP01929231.7
申请日：2001-02-28
申请人： JenaValve Technology Inc.
发明人： WEBER, Carsten , PESCHEL, Thomas , DAMM, Christoph , FIGULLA, Hans-Reiner , FERRARI, Markus
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2230/0054 , Y10S623/90
摘要： The invention relates to a device for fastening and anchoring cardiac valve prostheses which is essentially formed out of wire-shaped interconnected elements. The aim of the invention is to be able to implant, in a minimally invasive manner, a device of this type via the aorta by compressing the device to make it smaller, and by extending the same at the site of implantation, whereby ensuring a secure retention and a secure sealing with regard to the aorta wall. To this end, the invention provides that for fastening and supporting a cardiac valve prosthesis, three identical pairs of arched elements are interconnected, with a configuration that is offset by 120 DEG , by means of solid body articulations. These solid body articulations carry out the function of pivot bearings.

10. 发明公开

EP1940321A1 VORRICHTUNG ZUR IMPLANTATION UND BEFESTIGUNG VON HERZKLAPPENPROTHESEN 有权
公开(公告)号：EP1940321A1
公开(公告)日：2008-07-09
申请号：EP06828826.5
申请日：2006-10-17
申请人： JenaValve Technology Inc.
发明人： FERRARI, Markus , FIGULLA, Hans-Reiner , DAMM, Christoph
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2427 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/82 , A61F2/95 , A61F2/958 , A61F2002/9528 , A61F2210/0014 , A61F2220/0025 , A61F2230/0054 , A61F2250/006
摘要： The invention relates to a device for the transvascular implantation and fastening of heart valve prostheses. Said device comprises a self-expanding heart valve stent (10) which can be inserted into a patient's aorta and is provided with a heart valve prosthesis (11) at the proximal end thereof. The aim of the invention is to optimize such a device in such a way that the heart valve prosthesis (11) can be implanted in a patient by means of a minimally invasive intervention, especially ensuring greater accuracy with which the prosthesis (11) is positioned on the patient's ventricle. Said aim is achieved by providing the inventive device with a self-expanding positional stent (20) in addition to the self-expanding heart valve stent (10). Said positional stent (20) can be inserted all the way to an aortic valve position of a patient while being embodied separately from the heart valve stent (10). The positional stent (20) and the heart valve stent (10) are configured so as to cooperate in the expanded states thereof in such a way that the positional stent (20) helps retain the heart valve stent (10) in the patient's aorta in a position relative to the heart valve which can be predefined by the positional stent (20).
摘要翻译：具有在其近端具有假体心脏瓣膜（11）的具有自扩张型心脏瓣膜支架（10）的假体心脏瓣膜的经血管植入和固定的装置可导入患者的主动脉。为了优化这种装置的目的在于可以以微创程序将假体心脏瓣膜（11）植入患者的程度，以确保患者心室中假体（11）的最佳定位精度，该装置包括可扩展到定位在患者体内的主动脉瓣的自扩张定位支架（20）。定位支架与心脏瓣膜支架（10）分开配置，使得两个支架分别以其展开状态相互作用，使得心脏瓣膜支架（10）由定位支架（20）保持在患者主动脉中的位置相对于由定位支架（20）预先确定的心脏瓣膜。

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