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1. 发明授权

EP2155115B1 MEDICAL DEVICE FOR TREATING A HEART VALVE INSUFFICIENCY OR STENOSIS 有权转让
公开(公告)号：EP2155115B1
公开(公告)日：2018-09-05
申请号：EP07821482.2
申请日：2007-10-17
申请人： JenaValve Technology, Inc.
发明人： JUNG, Johannes , STRAUBINGER, Helmut , FERRARI, Markus , FIGULLA, Hans Reiner , GUYENOT, Volker , PESCHEL, Thomas , DAMM, Christoph
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2220/0016 , A61F2230/0054
摘要： The present application relates to a self expandable endoprosthesis for treating a heart valve insufficiency. In order to provide a self -expandable heart valve stent which can be introduced into a patient's body with minimal invasion for positioning and securing a heart valve prosthesis, for example, in the aorta of a patient, the inventive endoprosthesis comprises at least one retaining means (55) for manoeuvring the endoprosthesis into and out of position within the patient.

2. 发明授权

EP2257243B1 STENT FOR THE POSITIONING AND ANCHORING OF A VALVULAR PROSTHESIS IN AN IMPLANTATION SITE IN THE HEART OF A PATIENT 无效
标题翻译：支架治疗的患者的心脏定位和固定人工心脏瓣膜到IMPLANTANTIONSSTELLE的
公开(公告)号：EP2257243B1
公开(公告)日：2014-05-07
申请号：EP09715000.7
申请日：2009-02-25
申请人： JenaValve Technology Inc.
发明人： STRAUBINGER, Helmut , JUNG, Johannes
IPC分类号： A61F2/24
CPC分类号： A61F2/82 , A61F2/2418 , A61F2/2436 , A61F2220/0058 , A61F2220/0075 , A61F2230/0023 , A61F2230/005 , A61F2230/0054

3. 发明公开

EP2155115A1 MEDICAL DEVICE FOR TREATING A HEART VALVE INSUFFICIENCY OR STENOSIS 有权转让
标题翻译：医疗设备，治疗心脏瓣膜功能不全或狭窄
公开(公告)号：EP2155115A1
公开(公告)日：2010-02-24
申请号：EP07821482.2
申请日：2007-10-17
申请人： Jenavalve Technology INC.
发明人： JUNG, Johannes , STRAUBINGER, Helmut , FERRARI, Markus , FIGULLA, Hans Reiner , GUYENOT, Volker , PESCHEL, Thomas , DAMM, Christoph
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2220/0016 , A61F2230/0054
摘要： The present application relates to a self expandable endoprosthesis for treating a heart valve insufficiency. In order to provide a self -expandable heart valve stent which can be introduced into a patient's body with minimal invasion for positioning and securing a heart valve prosthesis, for example, in the aorta of a patient, the inventive endoprosthesis comprises at least one retaining means (55) for manoeuvring the endoprosthesis into and out of position within the patient.

4. 发明公开

EP2150210A1 HANDLE FOR MANIPULATING A CATHETER TIP, CATHETER SYSTEM AND MEDICAL INSERTION SYSTEM FOR INSERTING A SELF-EXPANDABLE HEART VALVE STENT 有权
标题翻译：手柄操纵导管尖端，导管制度和医疗系统技术创建自扩展的心瓣膜支架
公开(公告)号：EP2150210A1
公开(公告)日：2010-02-10
申请号：EP08749437.3
申请日：2008-05-12
申请人： JenaValve Technology, Inc.
发明人： STRAUBINGER, Helmut , JUNG, Johannes , PESCHEL, Thomas , DAMM, Christoph , GUYENOT, Volker
IPC分类号： A61F2/84 , A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2002/9517 , A61M25/0147
摘要： This invention is directed to a handle (70) for manipulating a catheter tip (10) of a catheter insertion system (100), with which a self-expandable heart valve stent (150) can be inserted into the body of a patient. The invention further concerns a catheter system (30) of a catheter insertion system (100) as well as a catheter insertion system (100) itself. The proposed catheter insertion system (100) is designed to enable the implantation of a heart valve prosthesis (160) attached to a heart valve stent (150) in the optimum implantation location in a sequence of events defined before the intervention. For this purpose, the catheter insertion system (100) comprises the handle (70) for manipulating the catheter tip (10) of the catheter insertion system (100), wherein the handle (70) comprises means (71, 81) that prescribe a pre-set sequence of steps such that each subsequent step is inhibited until the preceding step has been completed.
摘要翻译：在膨胀阀的支架插入到患者的身体和植入的支架瓣膜的方法的导管插入系统。导管插入系统包括具有用于操纵导管末端上的手柄的导管，并且能够附接至阀支架瓣膜假体的植入。所述手柄被配置为启用的步骤的预先设定的顺序来操纵导管尖端和按顺序释放所述瓣膜支架。导管尖端配置为顺序地释放从第一折叠模式下的阀支架的第二扩展模式。

5. 发明公开

EP2571460A2 CATHETER SYSTEM FOR INTRODUCING AN EXPANDABLE HEART VALVE STENT INTO THE BODY OF A PATIENT, INSERTION SYSTEM WITH A CATHETER SYSTEM AND MEDICAL DEVICE FOR TREATMENT OF A HEART VALVE DEFECT 有权转让
标题翻译：导管系统用于心脏瓣膜扩张支架患者体内有用于心脏瓣膜的麻烦治疗的导管系统和医疗设备介绍，介绍人
公开(公告)号：EP2571460A2
公开(公告)日：2013-03-27
申请号：EP11722739.7
申请日：2011-05-20
申请人： Jenavalve Technology INC.
发明人： STRAUBINGER, Helmut , MAYER, Arnulf , JUNG, Johannes
IPC分类号： A61F2/84 , A61F2/24 , A61M25/09
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/2433 , A61F2/966 , A61F2002/9505 , A61F2002/9517 , A61F2002/9665 , A61F2210/0014 , A61M2025/09141
摘要： The invention relates to catheter system for introducing an expandable heart valve stent (150) into the body of a patient, the catheter system comprising: a catheter tip (10) having a seat portion for accommodating the stent (150) in its collapsed state and a stent holder (15) for releasably fixing the stent (150), wherein the seat portion is constituted by a first sleeve-shaped member (11) and a second sleeve-shaped member (21), said sleeve-shaped members (11, 21) being moveable relative to each other and relative to the stent holder (15), and a catheter shaft (30) for connecting the catheter tip (10) to a handle (70). The catheter shaft (30) comprising: first force transmitting means (31) connected to the first sleeve-shaped member (11), second force transmitting means (41) connected to the second sleeve-shaped member (21) and a distal end section connectable to second operating means (81) of the handle (70), and guiding means (51) having a passageway extending there between, wherein the first and second force transmitting means (31, 41) are at least partly received within the passageway such as to be moveable relative to the guiding means (51), and wherein the proximal end of the guiding means (51) terminates distal to the catheter tip (10).

6. 发明公开

EP2400923A1 STENT FOR THE POSITIONING AND ANCHORING OF A VALVULAR PROSTHESIS IN AN IMPLANTATION SITE IN THE HEART OF A PATIENT 有权转让
标题翻译：支架在定位和固定一个皮瓣移植中的一个点在患者植入心脏
公开(公告)号：EP2400923A1
公开(公告)日：2012-01-04
申请号：EP10706605.2
申请日：2010-02-25
申请人： JenaValve Technology Inc.
发明人： STRAUBINGER, Helmut , JUNG, Johannes , GIRARD, Michael J. , MAYER, Arnulf
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2220/0016 , A61F2220/0058 , A61F2220/0075 , A61F2230/0023 , A61F2230/0054
摘要： The present invention relates to a stent (10) for the positioning and anchoring of a valvular prosthesis (100) in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and/or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis (100) fastened to a stent (10) will occur relative the stent (10) in the implanted state of the stent (10), even given the peristaltic motion of the heart, the stent (10) according to the invention comprises at least one fastening portion (11, 11a) via which the valvular prosthesis (100) is connectable to the stent (10). The stent (10) further comprises positioning arches (15a, 15b, 15c) and retaining arches (16a, 16b, 16c), whereby at least one positioning arch (15a, 15b, 15c) is connected to at least one retaining arch (16a, 16b, 16c).

7. 发明授权

EP2150210B1 HANDLE FOR MANIPULATING A CATHETER TIP, CATHETER SYSTEM AND MEDICAL INSERTION SYSTEM FOR INSERTING A SELF-EXPANDABLE HEART VALVE STENT 有权
标题翻译：手柄操纵导管尖端，导管制度和医疗系统技术创建自扩展的心瓣膜支架
公开(公告)号：EP2150210B1
公开(公告)日：2016-10-12
申请号：EP08749437.3
申请日：2008-05-12
申请人： JenaValve Technology, Inc.
发明人： STRAUBINGER, Helmut , JUNG, Johannes , PESCHEL, Thomas , DAMM, Christoph , GUYENOT, Volker
IPC分类号： A61F2/24 , A61F2/95
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2002/9517 , A61M25/0147

8. 发明公开

EP2768432A1 CATHETER SYSTEM FOR INTRODUCING AN EXPANDABLE HEART VALVE STENT INTO THE BODY OF A PATIENT, INSERTION SYSTEM WITH A CATHETER SYSTEM AND MEDICAL DEVICE FOR TREATMENT OF A HEART VALVE DEFECT 审中-公开
标题翻译：导管系统用于心脏瓣膜扩张支架患者体内有用于心脏瓣膜的麻烦治疗的导管系统和医疗设备介绍，介绍人
公开(公告)号：EP2768432A1
公开(公告)日：2014-08-27
申请号：EP12758471.2
申请日：2012-09-11
申请人： JenaValve Technology Inc.
发明人： STRAUBINGER, Helmut , LITZENBURGER, Michael , TÖLLNER, Thomas
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2002/9517
摘要： The invention relates to catheter system for introducing an expandable heart valve stent (150) into the body of a patient, the catheter system comprising : a catheter tip (10) having a seat portion for accommodating the stent (150) in its collapsed state and a stent holder (15) for releasably fixing the stent (150), wherein the seat portion is constituted by a first sleeve-shaped member (11) and a second sleeve-shaped member (21), said sleeve-shaped members (11, 21) being moveable relative to each other and relative to the stent holder (15), and a catheter shaft (30) for connecting the catheter tip (10) to a handle (70). The catheter shaft (30) comprising : first force transmitting means (31) connected to the first sleeve-shaped member (11), second force transmitting means (41) connected to the second sleeve-shaped member (21) and a distal end section connectable to second operating means (81) of the handle (70), and guiding means (51) having a passageway extending there between, wherein the first and second force transmitting means (31, 41) are at least partly received within the passageway such as to be moveable relative to the guiding means (51), and wherein the proximal end of the guiding means (51) terminates distal to the catheter tip (10).
摘要翻译：本发明涉及一种导管系统，用于引入到可扩张心脏瓣膜支架（150）插入患者体内，所述导管系统包括：一个导管末端（10）具有座部分，用于在其塌缩状态下容纳所述支架（150）和一支架托座（15），用于可释放地固定worin座部支架（150）由第一套筒形部件（11）和第二套筒形部件（21），所述套管形部件（11构成的， 21）可相对于彼此和相对于支架保持器（15），和用于将导管尖端（10）连接到手柄（70）的导管轴（30）可移动的。连接到连接到第二套筒形部件（21）和远端部分的第一个套筒形部件（11），第二力传递装置（41），第一力传递装置（31）：导管轴（30）包括连接到所述手柄的第二操作装置（81）（70）和引导装置（51）具有通道之间延伸有，worin所述第一和第二力的反式采矿装置（31，41）在所述通道内的至少部分地接收：如能相对可移动到所述引导装置（51），和worin所述引导装置的所述近端（51）终止于远侧导管尖端（10）。

9. 发明公开

EP2538878A1 STENT FOR THE POSITIONING AND ANCHORING OF A VALVULAR PROSTHESIS IN AN IMPLANTATION SITE IN THE HEART OF A PATIENT 有权转让
标题翻译：支架治疗的患者的心脏定位和固定人工心脏瓣膜到IMPLANTANTIONSSTELLE的
公开(公告)号：EP2538878A1
公开(公告)日：2013-01-02
申请号：EP11705868.5
申请日：2011-02-23
申请人： JenaValve Technology Inc.
发明人： STRAUBINGER, Helmut , JUNG, Jonannes , GIRARD, Michael J. , MAYER, Arnulf
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2230/0023
摘要： The present invention relates to a stent (10) for the positioning and anchoring of a valvular prosthesis (100) in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and/or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis (100) fastened to a stent (10) will occur relative the stent (10) in the implanted state of the stent (10), even given the peristaltic motion of the heart, the stent (10) according to the invention comprises at least one fastening portion (11 Ha) via which the valvular prosthesis (100) is connectable to the stent (10). The stent (10) further comprises positioning arches (15a, 15b, 15c) and retaining arches (16a, 16b, 16c), whereby at least one positioning arch (15a, 15b, 15c) is connected to at least one retaining arch (16a, 16b, 16c).

10. 发明公开

EP2429460A1 DEVICE FOR COMPRESSING A STENT AS WELL AS SYSTEM AND METHOD FOR LOADING A STENT INTO A MEDICAL DELIVERY SYSTEM 审中-公开
标题翻译：装置进行压缩和装载支架在医疗释放系统支架系统和方法
公开(公告)号：EP2429460A1
公开(公告)日：2012-03-21
申请号：EP10719344.3
申请日：2010-05-12
申请人： JenaValve Technology Inc.
发明人： STRAUBINGER, Helmut , MAYER, Arnulf , JUNG, Johannes , GIRARD, Michael, J. , LANE, Randy , MILLER, Amir
IPC分类号： A61F2/84 , A61F2/24
CPC分类号： A61F2/95 , A61F2/2412 , A61F2/2427 , A61F2002/9505 , A61F2002/9522
摘要： The invention relates to a device (1a-1d) for compressing a stent (100) or a stent (100) with a prosthetic heart valve affixed thereto. The invention further relates to a system as well as a method for loading a stent (100) into a medical delivery system. The device (1a-1d) according to the invention comprises a compressing mechanism (10a-10d), within which a stent (100) to be compressed can be at least partly accommodated, wherein the compressing mechanism (10a-10d) comprises externally- manipulatable clamping means (50; 70.1-70. n; 90.1-90. n; 110.1-110. n) and is designed so as to exert a compressive force in radial direction on at least parts of a stent (100) accommodated within the compressing mechanism (10a-10d) such that the cross-section of the stent (100) is reduced to a predefinable value at least at certain areas. The inventive device (1a-1d) further comprises a manipulating mechanism (40a-40d) for manipulating the at least one clamping means (50; 70.1- 70. n; 90.1-90. n; 110.1-110. n), said manipulating mechanism (40a-40d) being moveable relative to the compressing mechanism (10a-10d) for moving the at least one clamping means (50; 70.1-70. n; 90.1-90. n; 110.1-110. n) in the radial direction in order to adjust the internal cross-sectional diameter of the compressing mechanism (10a-10d).

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