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1. 发明公开

EP4053565A1 AUTOMATED ANALYZER 有权
公开(公告)号：EP4053565A1
公开(公告)日：2022-09-07
申请号：EP22171044.5
申请日：2016-07-25
申请人： Hitachi High-Tech Corporation
发明人： MAKINO, Akihisa , INABE, Toshiyuki , YABUTANI, Chie
IPC分类号： G01N35/02 , G01N33/86 , G01N35/04 , G01N35/00
摘要： In blood coagulation time measurement, the reaction time relies on the blood coagulation ability of a specimen and is not fixed. In particular, in module-type devices, errors may occur in the specimen processing, measurement number, and measurement time between a plurality of blood coagulation analysis units, leading to the risk of lowering the processing capability of the device as a whole. The present invention is a module-type automated analyzer provided with a plurality of blood coagulation analysis units capable of analyzing blood coagulation time items in which the reaction time between a specimen and a reagent differs depending on the specimen, wherein a control unit that controls the specimen rack conveying operation finds the total of forecasted measurement times of measurement items requested for specimens being analyzed and queued specimens in each of the plurality of blood coagulation analysis units, and determines the conveyance destination of the specimen rack on the basis of the total of the forecasted measurement times that was found.

2. 发明公开

EP4198518A1 CALIBRATION CURVE GENERATION METHOD, AUTONOMOUS ANALYSIS DEVICE, AND CALIBRATION CURVE GENERATION PROGRAM 审中-实审
公开(公告)号：EP4198518A1
公开(公告)日：2023-06-21
申请号：EP21855781.7
申请日：2021-02-19
申请人： HITACHI HIGH-TECH CORPORATION
发明人： YAMAMOTO, Kyoko , ADACHI, Sakuichiro , YABUTANI, Chie
IPC分类号： G01N35/00 , G01N21/27 , G01N21/59
摘要： An object of the present invention is to suppress time and effort into generating a calibration curve while ensuring accuracy of the calibration curve in an analysis step of generating the calibration curve by using two or more standard solutions (two or more concentrations). A calibration curve generation method according to the present invention includes acquiring time course data by irradiating a mixed reaction liquid obtained by mixing one standard solution containing a component to be measured having a concentration other than a zero concentration and a reagent reacting with the component to be measured with light and measuring a turbidity change over time of the mixed reaction liquid, extracting pieces of light amount data in a plurality of different times from a fitting line obtained by complementing discrete portions of the time course data, and generating the calibration curve indicating a relationship between the plurality of pieces of light amount data and a plurality of concentrations by converting the plurality of different times into the plurality of concentrations of the component to be measured ( FIG. 1 ).

3. 发明公开

EP4293361A3 AUTOMATED ANALYZER AND AUTOMATED ANALYSIS METHOD 审中-实审
公开(公告)号：EP4293361A3
公开(公告)日：2024-07-03
申请号：EP23200938.1
申请日：2018-09-06
申请人： HITACHI HIGH-TECH CORPORATION
发明人： KAZAMA, Yuto , IIJIMA, Masahiko , YABUTANI, Chie , KOGURE, Kenji
IPC分类号： G01N35/00 , G01N35/02
CPC分类号： G01N2035/00920130101 , G01N35/00722 , G01N35/00603 , G01N35/00712
摘要： The present invention makes it possible for an automated analyzer including two or more types of photometers to obtain suitable output of the measurement results of the plurality of photometers and suitable data alarm output even if there is an abnormality, or the like, at the time of measurement. This automated analyzer includes, for example, two types of photometers having different quantitative ranges and an analysis control unit for controlling analysis that includes measurement of a given sample using the two types of photometers. If two types of data alarms corresponding to abnormalities, or the like, during measurement have been added to the two types of measurement results from the two types of photometers (step S204(C)), the analysis control unit selects measurement result and data alarm output corresponding to the combination of the two types of data alarms and outputs the same to a user as analysis results (step S205) .

4. 发明公开

EP3859350A1 AUTOMATIC ANALYSIS SYSTEM 审中-实审
公开(公告)号：EP3859350A1
公开(公告)日：2021-08-04
申请号：EP19866988.9
申请日：2019-06-27
申请人： Hitachi High-Tech Corporation
发明人： SASAKI, Nobuhiko , SAWADA, Takanori , SHIMAMORI, Toshiyuki , YABUTANI, Chie
IPC分类号： G01N35/10
摘要： According to the present invention, a chemical dispensing mechanism 115 is provided with a liquid surface sensor for detecting the liquid surface of a chemical. A chemical container 122 is mounted on a chemical disk 116. A computer 132 has a calculation control unit comprising a control unit 140 and a calculation unit 141 and generating a control signal for controlling the operation of the chemical dispensing mechanism 115. The calculation control unit performs a first raising operation, in which a chemical stored in the chemical container 122 is suctioned by the chemical dispensing mechanism 115 and the chemical dispensing mechanism is then raised up to a first bubble detection position, determines whether a liquid surface is present by acquiring the detection result of the liquid surface sensor, and outputs an alert indicating the presence of a bubble on the liquid surface when the liquid surface has been determined to be absent. The first bubble detection position is the position at which the tip section of a dispensing nozzle of the chemical dispensing mechanism 115 remains inside the liquid when there are no bubbles present on the liquid surface, and is exposed from the inside of the liquid when there are bubbles present on the liquid surface.

5. 发明授权

EP3128330B1 AUTOMATIC ANALYTICAL APPARATUS 有权转让
公开(公告)号：EP3128330B1
公开(公告)日：2020-05-06
申请号：EP15773133.2
申请日：2015-03-09
申请人： Hitachi High-Tech Corporation
发明人： TARUMI, Shinji , ADACHI, Sakuichiro , YABUTANI, Chie , MAKINO, Akihisa
IPC分类号： G01N21/51 , G01N21/27 , G01N21/59 , G16H10/40 , G01N33/49 , G01N21/82 , G01N33/86 , G01N21/13 , G16H50/20

6. 发明公开

EP4425145A2 AUTOMATIC ANALYSIS DEVICE AND AUTOMATIC ANALYSIS METHOD 审中-实审
公开(公告)号：EP4425145A2
公开(公告)日：2024-09-04
申请号：EP24188187.9
申请日：2016-02-12
申请人： HITACHI HIGH-TECH CORPORATION
发明人： YABUTANI, Chie , SUZUKI, Naoto , MAKINO, Akihisa
IPC分类号： G01N1/38
CPC分类号： G01N33/96 , G01N21/272 , G01N33/4905 , G01N21/82 , G01N1/38 , G01N2035/0053420130101 , G01N2035/0054420130101 , G01N2035/0055420130101 , G01N2035/044420130101 , G01N33/86 , G01N35/025
摘要： Provided are an analysis device and a method that enable automated preparation of mixed blood plasma obtained by mixing subject blood plasma and normal blood plasma at a prescribed ratio. The automatic analysis device 100 is provided with: a specimen dispensing mechanism 101 that dispenses subject blood plasma and/or normal blood plasma to be added to correct the coagulation time of the subject blood plasma, into a plurality of specimen containers 103; reaction containers 104 that contain the subject blood plasma and/or the normal blood plasma; a reagent dispensing mechanism 106 that dispenses a reagent into the reaction containers 104; and a detecting unit 113 which applies light from a light source 115 to the subject blood plasma and/or the normal blood plasma to which the reagent is added in the reaction containers 104, and which measures the coagulation time on the basis of the obtained scattered light and/or transmitted light. The specimen dispensing mechanism 101 dispenses the subject blood plasma alone, the normal blood plasma alone, and the subject blood plasma and the normal blood plasma at least at one mixing ratio, into the plurality of specimen containers 103, thereby preparing mixed blood plasma.

7. 发明公开

EP4293361A2 AUTOMATED ANALYZER AND AUTOMATED ANALYSIS METHOD 审中-实审
公开(公告)号：EP4293361A2
公开(公告)日：2023-12-20
申请号：EP23200938.1
申请日：2018-09-06
申请人： HITACHI HIGH-TECH CORPORATION
发明人： KAZAMA, Yuto , IIJIMA, Masahiko , YABUTANI, Chie , KOGURE, Kenji
IPC分类号： G01N35/02
摘要： The present invention makes it possible for an automated analyzer including two or more types of photometers to obtain suitable output of the measurement results of the plurality of photometers and suitable data alarm output even if there is an abnormality, or the like, at the time of measurement. This automated analyzer includes, for example, two types of photometers having different quantitative ranges and an analysis control unit for controlling analysis that includes measurement of a given sample using the two types of photometers. If two types of data alarms corresponding to abnormalities, or the like, during measurement have been added to the two types of measurement results from the two types of photometers (step S204(C)), the analysis control unit selects measurement result and data alarm output corresponding to the combination of the two types of data alarms and outputs the same to a user as analysis results (step S205) .

8. 发明公开

EP4246148A3 AUTOMATIC ANALYSIS DEVICE 审中-实审
公开(公告)号：EP4246148A3
公开(公告)日：2023-12-06
申请号：EP23183471.4
申请日：2018-02-15
申请人： HITACHI HIGH-TECH CORPORATION
发明人： YABUTANI, Chie , YAMADA, Takumi , IIJIMA, Masahiko
IPC分类号： G01N35/00 , G01N35/02 , G01N35/04
摘要： An automatic analysis device according to the present invention is provided with a reagent disk configured to hold a plurality of reagent containers that is configured to a accommodate a reagent; at least two or more different measuring units configured to respectively perform different types of analysis using the reagent; a control part configured to control the measuring units; and a display part configured to display a reagent overview screen indicating information on a remaining amount of reagent and arrangement each of the plurality of reagent container hold on the reagent disk, as detailed information about reagents used in each of the two or more measuring units. When at least one of the two or more measuring units is not selected for use in the unit necessity-of-use selection part that allows selecting of necessity-of-use of each of the two or more measuring units, the display part is controlled so as not to display the information on the remaining amount of reagent and arrangement of the reagent container of the measuring unit, which is not selected for use, on the reagent overview screen. When at least one of the two or more measuring units is selected for use in the unit necessity-of-use selection part that allows selecting of necessity-of-use of each of the two or more measuring units, the display part is controlled so as to display the information on the remaining amount of reagent and arrangement of the reagent container of the measuring unit, which is selected for use, on the reagent overview screen.

9. 发明公开

EP3734288A1 AUTOMATED ANALYZER AND AUTOMATED ANALYSIS METHOD 有权
公开(公告)号：EP3734288A1
公开(公告)日：2020-11-04
申请号：EP18893760.1
申请日：2018-09-06
申请人： Hitachi High-Tech Corporation
发明人： KAZAMA, Yuto , IIJIMA, Masahiko , YABUTANI, Chie , KOGURE, Kenji
IPC分类号： G01N35/00 , G01N35/02
摘要： The present invention makes it possible for an automated analyzer including two or more types of photometers to obtain suitable output of the measurement results of the plurality of photometers and suitable data alarm output even if there is an abnormality, or the like, at the time of measurement. This automated analyzer includes, for example, two types of photometers having different quantitative ranges and an analysis control unit for controlling analysis that includes measurement of a given sample using the two types of photometers. If two types of data alarms corresponding to abnormalities, or the like, during measurement have been added to the two types of measurement results from the two types of photometers (step S204(C)), the analysis control unit selects measurement result and data alarm output corresponding to the combination of the two types of data alarms and outputs the same to a user as analysis results (step S205).

10. 发明公开

EP4246148A2 AUTOMATIC ANALYSIS DEVICE 审中-实审
公开(公告)号：EP4246148A2
公开(公告)日：2023-09-20
申请号：EP23183471.4
申请日：2018-02-15
申请人： HITACHI HIGH-TECH CORPORATION
发明人： YABUTANI, Chie , YAMADA, Takumi , IIJIMA, Masahiko
IPC分类号： G01N35/04
摘要： An automatic analysis device according to the present invention is provided with a reagent disk configured to hold a plurality of reagent containers that is configured to a accommodate a reagent; at least two or more different measuring units configured to respectively perform different types of analysis using the reagent; a control part configured to control the measuring units; and a display part configured to display a reagent overview screen indicating information on a remaining amount of reagent and arrangement each of the plurality of reagent container hold on the reagent disk, as detailed information about reagents used in each of the two or more measuring units. When at least one of the two or more measuring units is not selected for use in the unit necessity-of-use selection part that allows selecting of necessity-of-use of each of the two or more measuring units, the display part is controlled so as not to display the information on the remaining amount of reagent and arrangement of the reagent container of the measuring unit, which is not selected for use, on the reagent overview screen. When at least one of the two or more measuring units is selected for use in the unit necessity-of-use selection part that allows selecting of necessity-of-use of each of the two or more measuring units, the display part is controlled so as to display the information on the remaining amount of reagent and arrangement of the reagent container of the measuring unit, which is selected for use, on the reagent overview screen.

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