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1. 发明授权

EP3241021B1 VALVE MANIFOLDS FOR SIMULATED MOVING BED CHROMATOGRAPHY 有权转让
公开(公告)号：EP3241021B1
公开(公告)日：2019-07-24
申请号：EP15822943.5
申请日：2015-12-23
申请人： GE Healthcare Bio-Sciences AB
发明人： GEBAUER, Klaus , OLOVSSON, Bjorn Markus
IPC分类号： G01N30/20 , B01D15/18 , G01N30/88 , G01N30/42

2. 发明公开

EP3234588A1 SYSTEM FOR BLENDING SOLUTIONS 有权转让
标题翻译：混合解决方案的系统
公开(公告)号：EP3234588A1
公开(公告)日：2017-10-25
申请号：EP15816740.3
申请日：2015-12-17
申请人： GE Healthcare Bio-Sciences AB
发明人： OLOVSSON, Bjorn Markus
IPC分类号： G01N30/32 , B01D15/16 , G01N30/86
CPC分类号： B01D15/16 , B01F3/0861 , B01F15/00227 , B01F15/00422 , B01F15/026 , G01N27/06 , G01N30/32 , G01N30/34 , G01N30/8658 , G01N2030/347
摘要： A system for blending solutions and a buffer solution is disclosed. In this system a switch valve is present capable of flowing one or more solutions, a low pressure pump for pumping the one or more solutions through the switch valve and a T-joint capable of receiving the one or more solutions through the low pressure pump and blending the one or more solutions with a buffer solution. A high pressure pump is present for collecting a blended solution.
摘要翻译：公开了一种用于混合溶液和缓冲溶液的系统。在该系统中，存在能够流动一种或多种溶液的开关阀，用于通过开关阀泵送一种或多种溶液的低压泵和能够通过低压泵接收一种或多种溶液的T形接头，以及将一种或多种溶液与缓冲溶液混合。高压泵用于收集混合溶液。

3. 发明公开

EP3230729A1 SYSTEM FOR PREPARING SOLUTIONS FOR CHROMATOGRAPHY 有权转让
标题翻译：制备色谱溶液的系统
公开(公告)号：EP3230729A1
公开(公告)日：2017-10-18
申请号：EP15807930.1
申请日：2015-12-10
申请人： GE Healthcare Bio-Sciences AB
发明人： OLOVSSON, Bjorn Markus
IPC分类号： G01N30/32 , B01D15/16 , G01N30/86
CPC分类号： B01D15/166 , B01D15/16 , B01D15/22 , B01F3/088 , B01F5/0403 , B01F15/0022 , B01F15/00227 , B01F15/00344 , B01F15/0243 , G01N30/32 , G01N30/34 , G01N30/8658 , G01N2030/324 , G01N2030/347
摘要： A system for preparing solutions for chromatography application is disclosed. The system comprises a T-jointfor preparing a buffer solution by mixing at least one first solution and a second solution. The T-jointreceives the second solution from a solution supply unit connected to the T-joint. Further one or more low pressure pumps supply the one or more first solutions into the T-joint. The high pressure pump collects the buffer solution and delivers it to a chromatography apparatus.
摘要翻译：公开了一种用于制备用于色谱应用的溶液的系统。该系统包括用于通过混合至少一种第一溶液和第二溶液来制备缓冲溶液的T型接头。 T型接头从连接到T型接头的溶液供应单元接收第二种解决方案。另外一个或多个低压泵将一个或多个第一溶液供应到T形接头中。高压泵收集缓冲溶液并将其输送到色谱设备。

4. 发明授权

EP3123164B1 METHOD AND VALVE IN A CONTINUOUS CHROMATOGRAPHY SYSTEM 有权转让
公开(公告)号：EP3123164B1
公开(公告)日：2018-10-17
申请号：EP15712294.6
申请日：2015-03-16
申请人： GE Healthcare Bio-Sciences AB
发明人： OLOVSSON, Bjorn Markus
IPC分类号： G01N30/20 , B01D15/18 , F16K11/074 , G01N30/44 , G01N30/80
CPC分类号： G01N30/20 , B01D15/1842 , F16K11/0743 , G01N30/44 , G01N30/80 , G01N2030/202
摘要： A method and a rotary valve (65) in a continuous chromatography system. The rotary valve (65) comprises a stator (5) with an inner stator face (5a), and a rotor (12) with an inner rotor face (12a) arranged in sealing contact with the inner stator face (5a). The stator (5) comprises at least a first and a second inlet orifices (81,81), at least two first outlet (85a) orifices, a second outlet orifice (87) and a third outlet orifice (89), and the rotor interconnection paths are arranged to: - in at least one rotary position connect the first inlet orifice to the second outlet orifice and the second inlet orifice to the third outlet orifice, and - in at least two other rotary positions connect the first inlet orifice with any one of the first outlet orifices at the same time as the second inlet orifice is connected to the second outlet orifice.

5. 发明公开

EP3241021A1 VALVE MANIFOLDS FOR SIMULATED MOVING BED CHROMATOGRAPHY 有权转让
标题翻译：用于模拟移动床色谱的阀门流路
公开(公告)号：EP3241021A1
公开(公告)日：2017-11-08
申请号：EP15822943.5
申请日：2015-12-23
申请人： GE Healthcare Bio-Sciences AB
发明人： GEBAUER, Klaus , OLOVSSON, Bjorn Markus
IPC分类号： G01N30/20 , B01D15/18 , G01N30/88 , G01N30/42
CPC分类号： B01D15/1842 , G01N30/20 , G01N30/42 , G01N30/88 , G01N2030/205 , G01N2030/8881
摘要： Go between a first portion of the central duct and an opposed second portion of the central duct, a first plurality of connectors, each connector of the first plurality of connectors for connecting to a distinct chromatographic separation column and/or feed or extraction tubing or to a connector of an adjacent manifold; a second plurality of connectors, each connector of the second plurality of connectors for connecting to a distinct chromatographic separation column and/or feed or extraction tubing or to a connector of an adjacent manifold; wherein said manifold body further defines: a first plurality of branch ducts, each branch duct of which extending from the first portion of the central duct to an individual one of the first plurality of connectors, each of the branch ducts of the first plurality of branch ducts comprising a closable branch valve providing selectable fluid communication between a respective connector and the first portion of the central duct, a second plurality of branch ducts, each branch duct of which extending from the second portion of the central duct to an individual one of the second plurality of connectors, each of the branch ducts of the second plurality of branch ducts comprising a closable branch valve providing selectable fluid communication between a respective connector and the second portion of the central duct; first and second ports in fluid communication with the centrally-located closable duct valve wherein said first port communicates with said first portion of the central duct and said second port communicates with said second portion of said central duct, wherein one of said first and second ports is further positioned to communicate with said central duct at a location between the centrally-located closable duct valve and the first and second plurality of branch ducts, respectively.

6. 发明公开

EP3123164A1 METHOD AND VALVE IN CONTINUOUS CHROMATOGRAPHY SYSTEM 有权转让
标题翻译： VERFAHREN通风系统ZUR KONTINUIERLICHEN CHROMATOGRAPHIE
公开(公告)号：EP3123164A1
公开(公告)日：2017-02-01
申请号：EP15712294.6
申请日：2015-03-16
申请人： GE Healthcare Bio-Sciences AB
发明人： OLOVSSON, Bjorn Markus
IPC分类号： G01N30/20 , B01D15/18 , F16K11/074 , G01N30/44 , G01N30/80
CPC分类号： G01N30/20 , B01D15/1842 , F16K11/0743 , G01N30/44 , G01N30/80 , G01N2030/202
摘要： A method and a rotary valve (65) in a continuous chromatography system. The rotary valve (65) comprises a stator (5) with an inner stator face (5a), and a rotor (12) with an inner rotor face (12a) arranged in sealing contact with the inner stator face (5a). The stator (5) comprises at least a first and a second inlet orifices (81,81), at least two first outlet (85a) orifices, a second outlet orifice (87) and a third outlet orifice (89), and the rotor interconnection paths are arranged to: - in at least one rotary position connect the first inlet orifice to the second outlet orifice and the second inlet orifice to the third outlet orifice, and - in at least two other rotary positions connect the first inlet orifice with any one of the first outlet orifices at the same time as the second inlet orifice is connected to the second outlet orifice.
摘要翻译：连续色谱系统中的方法和旋转阀（65）。旋转阀（65）包括具有内定子面（5a）的定子（5）和具有与内定子面（5a）密封接触的内转子面（12a）的转子（12）。定子（5）至少包括第一和第二入口孔口（81,81），至少两个第一出口孔口（85a），第二出口孔口（87）和第三出口孔口（89），转子互连路径被布置成： - 在至少一个旋转位置中，将第一入口孔连接到第二出口孔，将第二入口孔连接到第三出口孔，并且 - 在至少两个其它旋转位置中，将第一入口孔与任何与第二入口孔同时的第一出口孔中的一个连接到第二出口孔。

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