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1. 发明授权

EP2413991B1 VORRICHTUNG ZUR ERMITTLUNG UND REGELUNG DER KONZENTRATION MINDESTENS EINES GELÖSTEN STOFFES IN EINEM FLUIDKREISLAUF 有权转让
标题翻译：用于确定和调节流体回路中至少一种溶剂的浓度的装置
公开(公告)号：EP2413991B1
公开(公告)日：2018-05-02
申请号：EP10712361.4
申请日：2010-03-31
申请人： Fresenius Medical Care Deutschland GmbH
发明人： GROSS, Malte , MAIERHOFER, Andreas
IPC分类号： A61M1/36 , A61M1/16
CPC分类号： A61M1/16 , A61M1/1605 , A61M1/1613 , A61M1/3609 , A61M2205/3317 , A61M2205/3324 , A61M2205/502 , A61M2205/52 , A61M2230/65

2. 发明公开

EP2349394A1 VERFAHREN UND VORRICHTUNG ZUR ERKENNUNG EINER PARAVASALEN BLUTUNG 有权
标题翻译：方法和设备检测循环血管周围
公开(公告)号：EP2349394A1
公开(公告)日：2011-08-03
申请号：EP09765018.8
申请日：2009-11-14
申请人： Fresenius Medical Care Deutschland GmbH
发明人： KOPPERSCHMIDT, Pascal , GROSS, Malte , SPICKERMANN, Reiner
IPC分类号： A61M1/36
CPC分类号： A61B5/02042 , A61M1/3639 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/18 , A61M2205/3331
摘要： The invention relates to a method and to a device for recognition of paravasal bleeding upon a supplying of blood to a vascular access via a line and/or upon the removal of blood from a vascular access via a line, particularly paravasal bleeding during extra-corporeal blood treatment, such as for hemodialysis, hemofiltration or hemodiafiltration. The invention furthermore relates to a device for extra-corporeal blood treatment, particularly for hemodialysis, hemofiltration or hemodiafiltration, comprising a device for recognition of paravasal bleeding. The method according to the invention and the device according to the invention are based on the change of arterial pressure in the arterial branch (5) or the venous pressure in the venous branch (7) of the extra-corporeal circuit (I) being registered during the extra-corporeal blood treatment. If paravasal bleeding occurs during the blood treatment, it is shown that the positive dynamic pressure on the line leading to the vascular access rises on the venous cannula during the extra-corporeal blood treatment, or the suction pressure on the line leaving the vascular access, such as the arterial cannula during extra-corporeal blood treatment, rises; that is, the suction pressure becomes more negative. The pressure rise begins moderately at first and then becomes increasingly greater. Decisive for the method according to the invention and the device according to the invention, therefore, is that pressure changes that come from a pressure level exhibiting a large difference from the reference value find stronger consideration than those that come from a pressure level that exhibits only a minor difference from the reference value.

3. 发明公开

EP1144024A3 VERFAHREN ZUR BESTIMMUNG DES VERTEILUNGSVOLUMENS EINES BLUTINHALTSSTOFFES WÄHREND EINER BLUTBEHANDLUNG UND VORRICHTUNG 审中-公开
标题翻译：确定血液处理和装置中血液成分分布容积的方法
公开(公告)号：EP1144024A3
公开(公告)日：2002-09-11
申请号：EP99964666.4
申请日：1999-12-23
申请人： Fresenius Medical Care Deutschland GmbH
发明人： GOLDAU, Rainer , GRAF, Thomas , GROSS, Malte
IPC分类号： A61M1/36

4. 发明授权

EP2185216B1 Dialysierflüssigkeitskreislauf, Dialysegerät mit Dialysierflüssigkeitskreislauf, Verfahren zur Erkennung von Luft in einer einen Dialysierflüssigkeitskreislauf durchströmenden Dialysierflüssigkeit sowie Verwendung eines Gassensors in einem Dialysierflüssigkeitskreislauf 有权
标题翻译：透析液，所述透析机的透析液，用于在流过透析液，以及在透析液电路中使用的气体传感器的透析液检测空气的方法
公开(公告)号：EP2185216B1
公开(公告)日：2013-03-20
申请号：EP08785230.7
申请日：2008-07-30
申请人： Fresenius Medical Care Deutschland GmbH
发明人： MAIERHOFER, Andreas , GAGEL, Alfred , GROSS, Malte
IPC分类号： A61M1/14
CPC分类号： A61M1/1656 , A61M2205/15

5. 发明公开

EP2413991A1 VORRICHTUNG UND VERFAHREN ZUR ERMITTLUNG UND REGELUNG DER KONZENTRATION MINDESTENS EINES GELÖSTEN STOFFES IN EINEM FLUIDKREISLAUF 有权转让
标题翻译：设备和方法确定和控制至少一种溶解物质的浓度在流体电路
公开(公告)号：EP2413991A1
公开(公告)日：2012-02-08
申请号：EP10712361.4
申请日：2010-03-31
申请人： Fresenius Medical Care Deutschland GmbH
发明人： GROSS, Malte , MAIERHOFER, Andreas
IPC分类号： A61M1/16
CPC分类号： A61M1/16 , A61M1/1605 , A61M1/1613 , A61M1/3609 , A61M2205/3317 , A61M2205/3324 , A61M2205/502 , A61M2205/52 , A61M2230/65
摘要： The invention relates to a device and method for determining and controlling the concentration of at least one solute in a fluid circuit, wherein the fluid circuit comprises at least two partial circuits, and wherein the partial circuits are separated by means of a filter in a semi-permeable manner.
摘要翻译：的装置和用于确定和在流体回路的至少一种溶解的物质，其中，所述流体回路包括通过一过滤器中的半渗透的方式分开的至少两个局部回路的浓度的调节的方法，包括：检测单元确定性挖掘的至少一个第一溶解的物质，用于确定性挖掘的判定单元的浓度差的至少一个第二溶解的物质的影响所有这些是不相同的所述至少一个第一溶解的物质，和一个调节单元，用于调节的浓度在流体回路中的至少一种溶解的物质。

6. 发明公开

EP1615680A1 BLUTBEHANDLUNGSVORRICHTUNG 有权
公开(公告)号：EP1615680A1
公开(公告)日：2006-01-18
申请号：EP04711604.1
申请日：2004-02-17
申请人： Fresenius Medical Care Deutschland GmbH
发明人： GROSS, Malte , WÜPPER, Andreas
IPC分类号： A61M1/16
CPC分类号： A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1617 , A61M2205/3317 , A61M2205/3324 , A61M2205/52 , A61M2230/65 , B01D61/32
摘要： The invention relates to a blood purification device comprising a blood purification element (1) that is divided into two chambers by a semi-permeable membrane (2), the first chamber (3) forming part of a dialysate circulation and the second chamber (4) forming part of an extracorporeal blood circulation. The invention enables a simple determination of the blood purification performance of the blood purification element for a second substance, said performance being derived and deviating from a previously determined blood purification performance for a first substance. The inventive haemodialysis device permits the determination of the concentration of the second substance in the blood during haemodialysis by measurements carried out on the dialysate, without the need for intervention in the course of dialysis, which was not possible in previous methods.
摘要翻译：本发明涉及一种血液净化装置，包括由半透膜（2）分成两个腔室的血液净化元件（1），第一腔室（3）形成透析液循环的一部分，第二腔室（4 ）构成体外血液循环的一部分。本发明能够简单地确定用于第二物质的血液净化元件的血液净化性能，所述性能是从第一物质的预先确定的血液净化性能中导出和偏离的。本发明的血液透析装置允许通过在透析液上进行测量来确定血液透析过程中血液中第二物质的浓度，而不需要在透析过程中介入，这在以前的方法中是不可能的。

7. 发明授权

EP2349394B1 VERFAHREN UND VORRICHTUNG ZUR ERKENNUNG EINER PARAVASALEN BLUTUNG 有权
标题翻译：方法和设备检测循环血管周围
公开(公告)号：EP2349394B1
公开(公告)日：2015-03-04
申请号：EP09765018.8
申请日：2009-11-14
申请人： Fresenius Medical Care Deutschland GmbH
发明人： KOPPERSCHMIDT, Pascal , GROSS, Malte , SPICKERMANN, Reiner
IPC分类号： A61M1/36
CPC分类号： A61B5/02042 , A61M1/3639 , A61M1/3653 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/18 , A61M2205/3331

8. 发明授权

EP2337509B1 VORRICHTUNG ZUR UMKEHR DES BLUTFLUSSES FÜR EINE EXTRAKORPORALE BLUTBEHANDLUNGSVORRICHTUNG UND VERFAHREN ZUR FESTSTELLUNG DER UMKEHR DES BLUTFLUSSES BEI EINER EXTRAKORPORALEN BLUTBEHANDLUNG 有权
标题翻译： DEVICE FOR逆转血流量的体外血液处理装置和方法的用于确定血流的逆转阿体外血液处理
公开(公告)号：EP2337509B1
公开(公告)日：2013-07-17
申请号：EP09744052.3
申请日：2009-10-02
申请人： Fresenius Medical Care Deutschland GmbH
发明人： MAIERHOFER, Andreas , GROSS, Malte
IPC分类号： A61B17/34 , A61M39/22
CPC分类号： A61M1/367 , A61M1/3656 , A61M1/3663 , A61M39/10 , A61M39/105 , A61M39/1055 , A61M39/22 , A61M39/223 , A61M2039/1044 , A61M2039/229 , A61M2205/3515 , A61M2205/3561 , A61M2205/3569 , A61M2205/6018 , A61M2205/6054 , F16K11/074

9. 发明公开

EP2421577A1 DIALYSEMASCHINE, VERFAHREN UND VORRICHTUNG FÜR EINE DIALYSEMASCHINE 有权转让
标题翻译： DIALYSEMASCHINE，VERFAHREN UND VORRICHTUNGFÜREINE DIALYSEMASCHINE
公开(公告)号：EP2421577A1
公开(公告)日：2012-02-29
申请号：EP10719908.5
申请日：2010-04-21
申请人： Fresenius Medical Care Deutschland GmbH
发明人： GROSS, Malte , MAIERHOFER, Andreas
IPC分类号： A61M1/16
CPC分类号： A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1613 , A61M2202/0498 , A61M2205/15 , A61M2205/18 , A61M2205/502 , A61M2205/52
摘要： The present invention relates to a dialysis machine, a method for operating a dialysis machine and a device for using a dialysis machine, wherein parameters for the dialysis treatment are entered, wherein, on the basis of a prescribed model including at least the previously entered parameters for at least one concentration of a dissolved substance, the profile of the change in concentration to be expected as a result of the dialysis treatment and/or the end value to be expected of the concentration of this substance in the vascular circulation of the patient is calculated and evaluated, and at least one signal and/or an indication is output by output means indirectly and/or directly in dependence on the evaluation of the profile of the change in concentration to be expected as a result of the dialysis treatment and the end value to be expected of the concentration of the substance and/or the dialysis treatment or the machine settings for the dialysis treatment is/are indirectly and/or directly influenced.
摘要翻译：本发明涉及一种透析机，透析机的操作方法和使用透析机的装置，其中进行透析处理的参数，其中，基于至少包括先前输入的参数的规定模型对于溶解物质的至少一个浓度，作为透析处理的结果所预期的浓度变化的曲线和/或该物质在患者的血管循环中的浓度的预期值的结果值是计算和评估，并且至少一个信号和/或指示由输出装置间接地和/或直接地依赖于作为透析治疗和结束所预期的浓度变化的分布的评估来输出对透析治疗的浓度和/或透析治疗或机器设置的预期值是间接的和/或直接影响

10. 发明公开

EP2247272A2 VORRICHTUNG UND VERFAHREN ZUR ÜBERWACHUNG EINES ZUGANGS ZU EINEM PATIENTEN, INSBESONDERE EINES GEFÄSSZUGANGS BEI EINER EXTRAKORPORALEN BLUTBEHANDLUNG 审中-公开
标题翻译：装置和方法，用于监视患者访问特定的血管通路AT A体外血液处理
公开(公告)号：EP2247272A2
公开(公告)日：2010-11-10
申请号：EP09717252.2
申请日：2009-03-03
申请人： Fresenius Medical Care Deutschland GmbH
发明人： GROSS, Malte
IPC分类号： A61F13/42 , A61M5/158
CPC分类号： A61M1/367 , A61M5/158 , A61M2005/1588 , A61M2205/15
摘要： The invention relates to the monitoring of an access to a patient at a puncture point, in particular the monitoring of the arterial and/or venous vascular access during an extracorporeal blood treatment. The device according to the invention, using which the exit of blood at the puncture point can be recognized, is implemented as a magnetoelastic moisture sensor (24), which is embedded in an absorbent material (25), which is laid on the puncture point (37). For the case in which infusion solution and/or blood exits from the puncture point (37), the incorrect seating of the puncture cannula (39) can be recognized reliably using the device according to the invention. The absorbent material (25) having the embedded magnetoelastic moisture sensor (24) can be laid like conventional bandage material or a gauze bandage on the puncture point. It is advantageous that using the device according to the invention, the requirements of hospital hygiene during dialysis are also fulfilled, because the puncture point is sterilely covered by laying on the device according to the invention. In addition, the device according to the invention may be provided cost-effectively in large piece counts as an article intended for single use and can be handled like conventional bandage material to avoid infections at puncture points. The monitoring of the patient access thus does not require additional measures.

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