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1. 发明授权

EP2936124B1 METHODS FOR EVALUATING MEDICAL MEASUREMENT CURVES 有权转让
标题翻译： VERFAHREN ZUR BEURTEILUNG MEDISINISCHER MESSKURVEN
公开(公告)号：EP2936124B1
公开(公告)日：2017-03-15
申请号：EP13811932.6
申请日：2013-12-19
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： AIGNER, Simon , CHEMNITIUS, Gabriele , HORN, Carina , LIMBURG, Bernd , OTTENSTEIN, Timo , PETRICH, Wolfgang , PLUM, Markus , RINGEMANN, Christian , SERR, Markus
IPC分类号： G01N21/77 , G01N21/84 , G01N21/27
CPC分类号： G06F19/24 , G01N21/274 , G01N21/77 , G01N21/8483 , G01N33/66 , G01N33/80 , G01N2201/129 , Y10T436/144444

2. 发明公开

EP4060347A1 METHOD FOR SCREENING A SUBJECT FOR THE RISK OF CHRONIC KIDNEY DISEASE AND COMPUTER-IMPLEMENTED METHOD 审中-公开
公开(公告)号：EP4060347A1
公开(公告)日：2022-09-21
申请号：EP21162683.3
申请日：2021-03-15
申请人： F. Hoffmann-La Roche AG , Roche Diabetes Care GmbH
发明人： RINGEMANN, Christian , HUSCHTO, Tony , KÖNIG, Helena
IPC分类号： G01N33/68
摘要： A method for screening a subject for the risk of chronic kidney disease (CKD) is provided, the method comprising: receiving marker data indicative for a plurality of marker parameters for a subject, such plurality of marker parameters indicating at least an age value, a time since diagnosis value indicative of a time since a diabetes diagnosis for the subject, a sample level of creatinine, an estimated glomerular filtration rate, a sample level of albumin, and a sample level of blood urea nitrogen; and determining a risk factor indicative of the risk of suffering CKD for the subject from the plurality of marker parameters. Further, a computer-implemented method for screening a subject for the risk of CKD is provided. Also, a system comprising a processor and a non-transitory memory storing a program causing the processor to perform the method for screening a subject for the risk of CKD is provided. In another aspect, a computer program product comprising instructions which, when the program is executed by a computer, cause the computer to carry out the method for screening a subject for the risk of CKD is provided.

3. 发明公开

EP3913640A1 METHOD AND SYSTEM FOR GENERATING A SOFTWARE-IMPLEMENTED MODULE FOR DETERMINING AN ANALYTE VALUE, COMPUTER PROGRAM PRODUCT, AND METHOD AND SYSTEM FOR DETERMINING AN ANALYTE VALUE 审中-实审转让
公开(公告)号：EP3913640A1
公开(公告)日：2021-11-24
申请号：EP20175348.0
申请日：2020-05-19
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG , International Business Machines Corporation
发明人： HUSCHTO, Tony , RINGEMANN, Christian , KLOPFENSTEIN, Yannick , BÜSSER, Alexander , RINDERKNECHT, Mike , MESTERHAZY, David , BECKA, Larissa
IPC分类号： G16H50/20 , G16H50/50
摘要： A method is disclosed for generating a software-implemented module for determining an analyte value, comprising, in an arrangement of one or more data processors: providing a first set of input data indicative of first values measured for a plurality of input parameters, the input parameters comprising a first and a second input parameter; and providing a second set of input data indicative of second values for the plurality of input parameters, the second values comprising an augmented value for at least one input parameter from the plurality of input parameters, the augmented value being different from the first value measured for the at least one input parameter and determined by augmenting the first value; and the first value for at least one remaining input parameter from the plurality of input parameters. The method further comprises: determining first analyte data indicative of a first plurality of analyte values for an analyte by processing the first set of input data by a physiological model; determining second analyte data indicative of a second plurality of analyte values for the analyte by processing the second set of input data by the physiological model; determining a set of training data from both the first analyte data and the second analyte data; determining a set of test data, the set test data being different from the set training data; providing a software-implemented machine learning model configured to determine an analyte value for the analyte; training the software-implemented machine learning model by the set of training data; and testing the software-implemented machine learning model by the set of test data. Furthermore, a system for generating a software-implemented module for determining an analyte value, a computer program product for generating a software-implemented module for determining an analyte value, a method for determining an analyte value, and a system for determining an analyte value are provided.

4. 发明授权

EP2976643B1 METHOD / DEVICE FOR GENERATING A CORRECTED VALUE OF AN ANALYTE CONCENTRATION IN A SAMPLE OF A BODY FLUID 有权转让
公开(公告)号：EP2976643B1
公开(公告)日：2019-06-05
申请号：EP14710588.6
申请日：2014-03-18
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： HOENES, Joachim , RINGEMANN, Christian , WELLER, Andreas
IPC分类号： G01N33/543

5. 发明公开

EP3327598A1 A SYSTEM AND A METHOD FOR AUTOMATICALLY ANALYZING CONTINUOUS GLUCOSE MONITORING DATA INDICATIVE OF GLUCOSE LEVEL IN A BODILY FLUID 审中-公开
公开(公告)号：EP3327598A1
公开(公告)日：2018-05-30
申请号：EP16200766.0
申请日：2016-11-25
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： RINGEMANN, Christian
IPC分类号： G06F19/00
CPC分类号： G16H50/70 , G16H20/13 , G16H20/60 , G16H40/63 , G16H50/20
摘要： The disclosure relates to a system for automatically analyzing continuous glucose monitoring data indicative of a glucose level in a bodily fluid, the system comprising an input device (3), a data processing device (1), an output device (4), and machine readable instructions that are executed by the data processing device (1), wherein the machine readable instructions cause the data processing device (1) to receive continuous glucose monitoring data via the input device (3), receive personal behavioral data, the personal behavioral data representing one or more behavioral parameters and, for the one or more behavioral parameters, indicating sensor signals sampled over time for the person; determine a plurality of glucose profiles from the continuous glucose monitoring data; cluster the plurality of glucose profiles into clustered groups; assign a selected behavioral parameter or a selected pattern of behavioral parameters from the one or more behavioral parameters to each glucose profile in a first clustered group, and provide analysis data to the output device. Further, a method and a computer program product are disclosed

6. 发明公开

EP3242233A1 SENSOR DEVICE FOR DETECTING AT LEAST ONE ANALYTE IN A BODY FLUID OF A USER 有权
标题翻译：用于检测用户身体流体中的至少一个分析物的传感器装置
公开(公告)号：EP3242233A1
公开(公告)日：2017-11-08
申请号：EP16168149.9
申请日：2016-05-03
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： RINGEMANN, Christian , STEIGER, Bernd
IPC分类号： G06F19/00
CPC分类号： G16H10/40 , G06F19/00 , G16H40/63
摘要： A sensor device (112) for detecting at least one analyte in a body fluid of a user is disclosed. The sensor device (112) comprises at least one evaluation device (134) configured for evaluating a data stream of time-dependent concentrations c of the analyte. The evaluation device (134) comprises at least one comparator device (140) configured for comparing a current value c(t) of the concentration c with at least one first threshold value L and with at least one second threshold value H, with H > L. The evaluation device (134) is configured to define a tolerance time interval (158). Further, the evaluation device (134), by using the comparator device (140), is configured to detect if the concentration c rises and exceeds the first threshold value L during the tolerance time interval (158) and to prepare a warning signal W accordingly. The evaluation device (134) is configured to suppress an output of the warning signal W at least until the tolerance time interval (158) expires, under the precondition that c(t)
摘要翻译：公开了一种用于检测用户的体液中的至少一种分析物的传感器装置（112）。传感器装置（112）包括至少一个评估装置（134），其被配置用于评估分析物的时间依赖性浓度c的数据流。评估装置（134）包括至少一个比较器装置（140），其被配置用于将浓度c的当前值c（t）与至少一个第一阈值L和至少一个第二阈值H进行比较，H> L.评估装置（134）被配置成限定公差时间间隔（158）。此外，通过使用比较装置（140），评估装置（134）被配置为检测浓度c是否在公差时间间隔（158）期间上升并超过第一阈值L并相应地准备警告信号W 。评估装置（134）被配置为在公差时间间隔（158）期间c（t）

7. 发明授权

EP3236851B1 METHOD AND SYSTEM FOR DETERMINING A BLOOD GLUCOSE LEVEL FOR A PATIENT 有权
公开(公告)号：EP3236851B1
公开(公告)日：2019-07-17
申请号：EP15808629.8
申请日：2015-12-14
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： SCHMELZEISEN-REDEKER, Günther , SCHMITT, Nikolaus , RINGEMANN, Christian
IPC分类号： A61B5/1486 , A61B5/1495 , G16H10/00

8. 发明公开

EP3478155A1 METHOD FOR PROVIDING A SIGNAL QUALITY DEGREE ASSOCIATED WITH AN ANALYTE VALUE MEASURED IN A CONTINUOUS MONITORING SYSTEM 审中-实审
公开(公告)号：EP3478155A1
公开(公告)日：2019-05-08
申请号：EP17733827.4
申请日：2017-06-28
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： RINGEMANN, Christian
IPC分类号： A61B5/00 , A61B5/145

9. 发明公开

EP3380839A1 METHOD AND APPARATUS FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN A BODY FLUID 有权
公开(公告)号：EP3380839A1
公开(公告)日：2018-10-03
申请号：EP16800918.1
申请日：2016-11-21
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： IBACH, Alexander , RINGEMANN, Christian , STEPHAN, Peter
IPC分类号： G01N33/52 , G01N21/84
摘要： The invention concerns a method and an apparatus for determining the concentration of an analyte in a body fluid, where the following measures are proposed: providing a layered test element (12) including an enzyme-based chemistry layer which is responsive to the analyte by a color change, applying a sample of the body fluid onto the test element (12), detecting by means of a photometric reflectance measuring device (16) a reflectance value of the test element (12), correcting the measured reflectance value by a predetermined offset value attributed to the test element (12), determining a concentration value of the analyte using the offset-corrected reflectance value.

10. 发明授权

EP3380839B1 METHOD AND APPARATUS FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN A BODY FLUID 有权
公开(公告)号：EP3380839B1
公开(公告)日：2019-11-06
申请号：EP16800918.1
申请日：2016-11-21
申请人： Roche Diabetes Care GmbH , F. Hoffmann-La Roche AG
发明人： IBACH, Alexander , RINGEMANN, Christian , STEPHAN, Peter
IPC分类号： G01N21/84 , G01N21/78 , C12Q1/00

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