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1. 发明授权

EP2714134B1 HEMODIALYSIS SYSTEM 有权
标题翻译：血液透析系统
公开(公告)号：EP2714134B1
公开(公告)日：2017-05-10
申请号：EP12726672.4
申请日：2012-05-24
申请人： DEKA Products Limited Partnership
发明人： GRANT, Kevin, L. , WILT, Michael, J. , TRACEY, Brian, D. , RUDOLF, Brett, A. , COLLINS, David, E. , PANNETON, Lisa, A. , DALE, James, D. , BODWELL, Jesse, T.
IPC分类号： A61M1/36
CPC分类号： A61M1/3653 , A61M1/14 , A61M1/1658 , A61M1/168 , A61M1/1682 , A61M1/1686 , A61M1/3643 , A61M1/3644 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3656 , A61M1/367 , A61M1/3672 , A61M2205/12 , A61M2205/121 , A61M2205/128 , Y10T137/87169
摘要： A blood circuit assembly engagement device for a dialysis unit, comprising: an actuator movably mounted to a panel of the dialysis unit adjacent a plurality of control ports, the actuator movable between a retention position and an ejection position; a retainer element coupled to the actuator and arranged, with the actuator in the retention position, to retain a blood circuit assembly mounted to the panel of the dialysis unit on the panel, and arranged, with the actuator in the ejection position, to release the blood circuit assembly for removal from the panel of the dialysis unit; and an ejector element coupled to the actuator and arranged, with the actuator moved from the retention position to the ejection position, to urge the blood circuit assembly away from the panel.
摘要翻译：用于透析单元的排出盒在静脉连接端口和动脉连接端口之间具有流体通道，并且阀门可以可控制地打开和关闭排出口端口与静脉连接端口或动脉连接端口之间的流体连通。血液回路组件和排出盒可以从透析单元移除，例如通过手动和不使用工具。血液回路组件可以包括限定一对血泵的部分，控制阀，准确定位用于封堵器的柔性管道，空气阱支撑件和/或组件的其他部分的单个单一构件。血液回路组件接合装置可以帮助将血液回路组件保持在透析单元上，和/或移除组件。致动器可以操作与组件相互作用的保持器元件和顶出元件。

2. 发明公开

EP2493526A2 APPARATUS AND METHOD FOR DETECTING DISCONNECTION OF AN INTRAVASCULAR ACCESS DEVICE 有权
标题翻译：设备和检测方法的分离用的血管内接入设备的
公开(公告)号：EP2493526A2
公开(公告)日：2012-09-05
申请号：EP10795810.0
申请日：2010-10-29
申请人： DEKA Products Limited Partnership
发明人： WILT, Michael, J. , SACHS, Jason, M. , GRANT, Kevin, L.
IPC分类号： A61M1/36 , G01N27/07
CPC分类号： A61M1/3656 , A61M1/3653 , A61M1/3655 , A61M1/3659 , A61M2205/3317 , G01N27/07 , G01R27/14
摘要： An apparatus and method are disclosed for detecting the disconnection of a vascular access device such as a needle, cannula or catheter from a blood vessel or vascular graft segment. A pair of electrodes is placed in direct contact with fluid or blood in fluid communication with the vascular segment. In one embodiment, the electrodes are incorporated into a pair of connectors connecting arterial and venous catheters to arterial and venous tubes leading to and from an extracorporeal blood flow apparatus. Wires leading from the electrodes to a detecting circuit can be incorporated into a pair of double lumen arterial and venous tubes connecting the blood flow apparatus to the blood vessel or vascular graft. The detecting circuit is configured to provide a low-voltage alternating current signal to the electrodes to measure the electrical resistance between the electrodes, minimizing both the duration and amount of current being delivered. Detection of an increase in electrical resistance between the electrodes exceeding a pre-deteπnined threshold value may be used to indicate a possible disconnection of the vascular access device.

3. 发明授权

EP2131886B1 PUMPING CASSETTE 有权
标题翻译：泵盒
公开(公告)号：EP2131886B1
公开(公告)日：2017-04-05
申请号：EP08730740.1
申请日：2008-02-26
申请人： DEKA Products Limited Partnership
发明人： DEMERS, Jason, A. , WILT, Michael, J. , GRANT, Kevin, L. , DALE, James, D. , TRACY, Brian
IPC分类号： A61M1/10
CPC分类号： F04B53/10 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1087 , A61M1/1096 , A61M1/16 , A61M1/1605 , A61M1/1639 , A61M1/1656 , A61M1/1664 , A61M1/1666 , A61M1/287 , A61M2205/12 , A61M2205/128 , A61M2205/3317 , A61M2205/3324 , A61M2205/3368 , F04B7/02 , F04B9/109 , F04B13/02 , F04B23/06 , F04B41/06 , F04B43/00 , F04B43/02 , F04B43/06 , F04B43/073 , F04B43/0733 , F04B43/0736 , F04B45/02 , F04B45/0536 , F04B49/22 , F04B53/06 , F04B53/16 , F17D3/00 , Y10T137/0324 , Y10T137/0379 , Y10T137/2521 , Y10T137/85978 , Y10T137/86139
摘要： There is disclosed herein a pump cassette comprising: a primary reciprocating membrane pump having a pumping chamber with an inlet of the reciprocating membrane pump fluidly connected to a first inlet of the cassette; a mixing chamber having an inlet fluidly connected to an outlet of the reciprocating membrane pump, and an outlet fluidly connected to an outlet of the cassette; a first metering pump having an inlet fluidly connected to a second inlet of the cassette, and an outlet fluidly connected to the inlet of the mixing chamber; and a second metering pump having an inlet fluidly connected to a third inlet of the cassette, and an outlet fluidly connected to the inlet of the reciprocating membrane pump, wherein 1) the pump cassette is arranged to receive a first fluid into the pumping chamber of the primary reciprocating membrane pump via the first inlet of the cassette, and to receive a second fluid via the third inlet of the cassette, the second fluid being pumped by the second metering pump into the pumping chamber of the primary reciprocating membrane pump, 2) the pump cassette is arranged to receive a third fluid via the second inlet of the cassette, the third fluid being pumped by the first metering pump into the mixing chamber, and 3) a pre-determined volume of first fluid and second fluid are mixed in the pumping chamber of the primary reciprocating membrane pump, and then pumped into the mixing chamber to be mixed with a pre-determined volume of third fluid pumped by the first metering pump.

4. 发明公开

EP2714134A2 HEMODIALYSIS SYSTEM 有权
标题翻译： HÄMODIALYSESYSTEM
公开(公告)号：EP2714134A2
公开(公告)日：2014-04-09
申请号：EP12726672.4
申请日：2012-05-24
申请人： DEKA Products Limited Partnership
发明人： GRANT, Kevin, L. , WILT, Michael, J. , TRACEY, Brian, D. , RUDOLF, Brett, A. , COLLINS, David, E. , PANNETON, Lisa, A. , DALE, James, D. , BODWELL, Jesse, T.
IPC分类号： A61M1/36
CPC分类号： A61M1/3653 , A61M1/14 , A61M1/1658 , A61M1/168 , A61M1/1682 , A61M1/1686 , A61M1/3643 , A61M1/3644 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3656 , A61M1/367 , A61M1/3672 , A61M2205/12 , A61M2205/121 , A61M2205/128 , Y10T137/87169
摘要： A blood circuit assembly engagement device for a dialysis unit, comprising: an actuator movably mounted to a panel of the dialysis unit adjacent a plurality of control ports, the actuator movable between a retention position and an ejection position; a retainer element coupled to the actuator and arranged, with the actuator in the retention position, to retain a blood circuit assembly mounted to the panel of the dialysis unit on the panel, and arranged, with the actuator in the ejection position, to release the blood circuit assembly for removal from the panel of the dialysis unit; and an ejector element coupled to the actuator and arranged, with the actuator moved from the retention position to the ejection position, to urge the blood circuit assembly away from the panel.
摘要翻译：用于透析单元的排出盒具有在静脉和动脉连接口之间的流体通道，并且阀可以可控地打开和关闭排出口与静脉连接口或动脉连接口之间的流体连通。血液回路组件和排出盒可以从透析单元移除，例如用手而不使用工具。血液回路组件可以包括单一的整体构件，其限定一对血液泵，控制阀，通道的部分，以准确地定位用于封堵器的柔性管，空气阱支撑件和/或组件的其它部分。血液回路组件接合装置可以帮助将血液回路组件保持在透析单元上和/或移除组件。致动器可以操作与组件相互作用的保持器元件和顶出器元件。

5. 发明公开

EP2197513A1 APPARATUS AND METHODS FOR HEMODIALYSIS 有权
标题翻译： Blutkreislaufanordnungfüreine Dialyseeinheit
公开(公告)号：EP2197513A1
公开(公告)日：2010-06-23
申请号：EP08838971.3
申请日：2008-10-10
申请人： Deka Products Limited Partnership
发明人： BODWELL, Jesse, T. , CHAWAN, Arun, D. , COLLINS, David, E. , DEMERS, Jason, A. , PRESCOTT, Shannon , KAMEN, Dean , MARCEK, Geoffrey, A. , GRANT, Kevin, L. , WILT, Michael, J. , DALE, James, D.
IPC分类号： A61M1/10
CPC分类号： A61M1/1656 , A61M1/0082 , A61M1/0084 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/16 , A61M1/1605 , A61M1/1633 , A61M1/1639 , A61M1/1662 , A61M1/1664 , A61M1/1666 , A61M1/1672 , A61M1/1682 , A61M1/1686 , A61M1/1696 , A61M1/3621 , A61M1/3627 , A61M39/1011 , A61M39/105 , A61M2039/1016 , A61M2039/1033 , A61M2205/12 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/50 , A61M2205/58 , A61M2209/08 , B01D61/30 , B01D61/32
摘要： An enclosure for containing a hemodialysis unit includes a housing (51) suitable to support components for performing hemodialysis including a dialyzer (14), one or more pumps to circulate blood through the dialyzer, a source of dialysate, and one or more pumps to circulate the dialysate through the dialyzer. The housing may have a front panel (511) at which blood circuit connections and dialysate fluidic connections are located, e.g., blood line connections for patient blood access, connections for a reagent supply, dialyzer connections for both blood flow and dialysate, etc. The enclosure may also include a pair of vertical, side-by-side doors (53) hingedly mounted to the housing. With the doors in the closed position, access to the patient access and dialysate fluidic connections may be blocked, and the doors may allow for the retention of heat in the housing suitable for disinfection during a disinfection cycle.
摘要翻译：本文公开了一种用于透析单元的血液回路组件（17），包括：组织托盘（171），包括电路管接合构件（174），每个电路管接合构件具有各自的电路管穿过的孔，接合构件与相应的电路管，以允许电路管被拉伸和拉伸以与透析单元的封堵器（513）接合; 安装在所述组织托盘上的一对气动泵（23），用于使从患者接收的血液循环通过包括透析器（14）的回路并返回到患者; 安装在所述组织托盘上的空气阱（19），其布置成从所述回路中循环的血液中除去空气; 一对连接到透析器（14）的入口和出口的透析器连接; 以及一对血液线连接器（203,204），一个入口血液线连接器，用于从患者接收血液并向气动泵提供血液，另一个出血血管连接器用于将血液返回给患者。还公开了将血液回路组件安装在透析单元上的相关方法。

6. 发明公开

EP2131889A1 HEMODIALYSIS SYSTEMS AND METHODS 有权
标题翻译： VERFAHREN公司的制造商
公开(公告)号：EP2131889A1
公开(公告)日：2009-12-16
申请号：EP08726213.5
申请日：2008-02-27
申请人： DEKA PRODUCTS LIMITED PARTNERSHIP
发明人： WILT, Michael, J. , DEMERS, Jason, A. , GRANT, Kevin, L. , TRACEY, Brian , DALE, James, D.
IPC分类号： A61M1/16 , A61M1/36
CPC分类号： A61M1/3672 , A61M1/16 , A61M1/1601 , A61M1/1621 , A61M1/1654 , A61M1/1694 , A61M1/267 , A61M1/3413 , A61M1/3424 , A61M1/3609 , A61M1/3621 , A61M1/3638 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M2205/12 , A61M2205/123 , A61M2205/128 , A61M2205/15 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/36 , A61M2205/505 , Y10T137/87893
摘要： The present invention generally relates to hemodialysis and similar dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. In one set of embodiments, a hemodialysis system may include a blood flow path and a dialysate flow path, where the dialysate flow path includes one or more of a balancing circuit, a mixing circuit, and/or a directing circuit. Preparation of dialysate by the preparation circuit, in some instances, may be decoupled from patient dialysis. In some cases, the circuits are defined, at least partially, within one or more cassettes, optionally interconnected with conduits, pumps, or the like. In one embodiment, the fluid circuit and/or the various fluid flow paths may be at least partially isolated, spatially and/or thermally, from electrical components of the hemodialysis system. In some cases, a gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer that, when activated, is able to urge dialysate to pass through the dialyzer and urge blood in the blood flow path back to the patient. Such a system may be useful, for example, in certain emergency situations (e.g., a power failure) where it is desirable to return as much blood to the patient as possible. The hemodialysis system may also include, in another aspect of the invention, one or more fluid handling devices, such as pumps, valves, mixers, or the like, which can be actuated using a control fluid, such as air. In some cases, the control fluid may be delivered to the fluid handling devices using an external pump or other device, which may be detachable in certain instances. In one embodiment, one or more of the fluid handling devices may be generally rigid (e.g., having a spheroid shape), optionally with a diaphragm contained within the device, dividing it into first and second compartments.
摘要翻译：公开了血液透析和类似的透析系统，包括流体流动回路。血液透析系统可以包括血流路径和包括平衡，混合和/或定向电路的透析液流动路径。透析液的制备可能与患者透析分离。电路可以在一个或多个盒中定义。流体回路和/或各种流体流动路径可以与电气部件隔离。可以提供气体供应，当被激活时，能够通过透析器促使透析液和血液返回给患者。这种系统在电源故障期间可能是有用的。血液透析系统还可以包括使用控制流体致动的流体处理装置，例如泵，阀，混合器等。可以使用可拆卸的外部泵将控制流体输送到流体处理装置。流体处理装置可以具有球形形状，其中隔膜将其分成两个隔室。

7. 发明授权

EP2131889B1 HEMODIALYSIS SYSTEMS AND METHODS 有权
公开(公告)号：EP2131889B1
公开(公告)日：2019-01-02
申请号：EP08726213.5
申请日：2008-02-27
申请人： DEKA PRODUCTS LIMITED PARTNERSHIP
发明人： WILT, Michael, J. , DEMERS, Jason, A. , GRANT, Kevin, L. , TRACEY, Brian , DALE, James, D.
IPC分类号： A61M1/16 , A61M1/36

8. 发明公开

EP2714123A2 BLOOD TREATMENT SYSTEMS AND METHODS 有权
标题翻译： BLUTBEHANDLUNGSSYSTEME在国外
公开(公告)号：EP2714123A2
公开(公告)日：2014-04-09
申请号：EP12743802.6
申请日：2012-05-24
申请人： DEKA Products Limited Partnership
发明人： WILT, Michael, J. , VAN DER MERWE, Dirk, A. , BALLANTYNE, Todd, A. , GRANT, Kevin, L. , ROSSE, Jonathan, P. , FLYNN, Catharine, N. , YEE, Brian, K.
IPC分类号： A61M1/10 , A61M1/16 , A61M1/34 , A61M1/36 , G06F1/16
CPC分类号： A61M1/1601 , A61K33/00 , A61M1/1006 , A61M1/1037 , A61M1/1062 , A61M1/1087 , A61M1/1096 , A61M1/14 , A61M1/16 , A61M1/1605 , A61M1/1613 , A61M1/1619 , A61M1/1654 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M1/1664 , A61M1/1666 , A61M1/1668 , A61M1/1692 , A61M1/267 , A61M1/301 , A61M1/34 , A61M1/341 , A61M1/3413 , A61M1/3609 , A61M1/3621 , A61M1/3627 , A61M1/3638 , A61M1/3672 , A61M5/172 , A61M2205/12 , A61M2205/15 , A61M2205/18 , A61M2205/3306 , A61M2205/3313 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/3379 , A61M2205/3569 , A61M2205/3584 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2230/65 , G06F19/00 , G06F19/3481
摘要： There is disclosed herein dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. In one set of embodiments, a hemodialysis system may include a blood flow path and a dialysate flow path, where the dialysate flow path includes one or more of a balancing circuit, a mixing circuit, and/or a directing circuit. Preparation of dialysate by the preparation circuit, in some instances, may be decoupled from patient dialysis. In some cases, the circuits are defined, at least partially, within one or more cassettes, optionally interconnected with conduits, pumps, or the like. In one embodiment, the fluid circuit and/or the various fluid flow paths may be at least partially isolated, spatially and/or thermally, from electrical components of the hemodialysis system. In some cases, a gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer that, when activated, is able to urge dialysate to pass through the dialyzer and urge blood in the blood flow path back to the patient. Such a system may be useful, for example, in certain emergency situations (e.g., a power failure) where it is desirable to return as much blood to the patient as possible. The hemodialysis system may also include, in another aspect of the invention, one or more fluid handling devices, such as pumps, valves, mixers, or the like, which can be actuated using a control fluid, such as air. In some cases, the control fluid may be delivered to the fluid handling devices using an external pump or other device, which may be detachable in certain instances. In one embodiment, one or more of the fluid handling devices may be generally rigid (e.g., having a spheroid shape), optionally with a diaphragm contained within the device, dividing it into first and second compartments.
摘要翻译：公开了透析系统，其包括新的流体流动回路。系统可以包括血液和透析液流动路径，其中透析液流动路径包括平衡，混合和/或引导电路。透析液的制备可能与患者透析分离。电路可以在一个或多个盒中定义。流体回路流体流动路径可以与电气部件隔离。与透析液流路和/或透析器流体连通的能够通过透析器促使透析液并将血液推回病人的气体供应可能包括在某些紧急情况下。可以包括可以使用控制流体致动的流体处理装置，例如泵，阀和混合器。控制流体可以由外部泵或其他装置输送，外部泵或其它装置可以是可拆卸的和/或大致刚性的，可选地具有将装置分成第一和第二隔室的隔膜。

9. 发明公开

EP2131886A1 PUMPING CASSETTE 有权
标题翻译： PUMPKASSETTE
公开(公告)号：EP2131886A1
公开(公告)日：2009-12-16
申请号：EP08730740.1
申请日：2008-02-26
申请人： Deka Products Limited Partnership
发明人： DEMERS, Jason, A. , WILT, Michael, J. , GRANT, Kevin, L. , DALE, James, D. , TRACY, Brian
IPC分类号： A61M1/10
CPC分类号： F04B53/10 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1087 , A61M1/1096 , A61M1/16 , A61M1/1605 , A61M1/1639 , A61M1/1656 , A61M1/1664 , A61M1/1666 , A61M1/287 , A61M2205/12 , A61M2205/128 , A61M2205/3317 , A61M2205/3324 , A61M2205/3368 , F04B7/02 , F04B9/109 , F04B13/02 , F04B23/06 , F04B41/06 , F04B43/00 , F04B43/02 , F04B43/06 , F04B43/073 , F04B43/0733 , F04B43/0736 , F04B45/02 , F04B45/0536 , F04B49/22 , F04B53/06 , F04B53/16 , F17D3/00 , Y10T137/0324 , Y10T137/0379 , Y10T137/2521 , Y10T137/85978 , Y10T137/86139
摘要： There is disclosed herein a pump cassette comprising: a primary reciprocating membrane pump having a pumping chamber with an inlet of the reciprocating membrane pump fluidly connected to a first inlet of the cassette; a mixing chamber having an inlet fluidly connected to an outlet of the reciprocating membrane pump, and an outlet fluidly connected to an outlet of the cassette; a first metering pump having an inlet fluidly connected to a second inlet of the cassette, and an outlet fluidly connected to the inlet of the mixing chamber; and a second metering pump having an inlet fluidly connected to a third inlet of the cassette, and an outlet fluidly connected to the inlet of the reciprocating membrane pump, wherein 1) the pump cassette is arranged to receive a first fluid into the pumping chamber of the primary reciprocating membrane pump via the first inlet of the cassette, and to receive a second fluid via the third inlet of the cassette, the second fluid being pumped by the second metering pump into the pumping chamber of the primary reciprocating membrane pump, 2) the pump cassette is arranged to receive a third fluid via the second inlet of the cassette, the third fluid being pumped by the first metering pump into the mixing chamber, and 3) a pre-determined volume of first fluid and second fluid are mixed in the pumping chamber of the primary reciprocating membrane pump, and then pumped into the mixing chamber to be mixed with a pre-determined volume of third fluid pumped by the first metering pump.
摘要翻译：这里公开了一种泵盒，包括：初级往复式膜泵，其具有泵送室，所述泵送室具有与所述盒的第一入口流体连接的所述往复膜泵的入口; 混合室具有流体连接到往复式膜泵的出口的入口和流体连接到盒的出口的出口; 第一计量泵，其具有流体连接到所述盒的第二入口的入口，以及流体连接到所述混合室的入口的出口; 以及第二计量泵，其具有流体连接到所述盒的第三入口的入口和与所述往复膜泵的入口流体连接的出口，其中1）所述泵盒被布置成将第一流体接收到泵送室所述主往复膜泵经由所述盒的第一入口并经由所述盒的第三入口接收第二流体，所述第二流体由所述第二计量泵泵送到所述主往复膜式泵的泵送室中; 2）泵盒被布置成经由盒的第二入口接收第三流体，第三流体被第一计量泵泵送到混合室中，以及3）将预定量的第一流体和第二流体混合在初级往复式膜泵的泵送室，然后泵入混合室以与由第一计量泵泵送的预定体积的第三流体混合。

10. 发明授权

EP2353119B1 HEMODIALYSIS SYSTEMS 有权
公开(公告)号：EP2353119B1
公开(公告)日：2020-04-15
申请号：EP09789214.5
申请日：2009-08-27
申请人： DEKA PRODUCTS LIMITED PARTNERSHIP
发明人： DEMERS, Jason, A. , WILT, Michael, J. , BALLANTYNE, Todd, A. , GRANT, Kevin, L. , DALE, James, D.
IPC分类号： A61M1/14 , A61M1/36

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