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    • 8. 发明公开
    • 2,2-difluoropropionic acid derivatives and a process for preparing the same
    • 2,2-二氟丙酸衍生物及其制备方法
    • EP0148490A1
    • 1985-07-17
    • EP84116103.7
    • 1984-12-21
    • DAIKIN INDUSTRIES, LIMITED
    • Ohsaka, YohnosukeTohzuka, TakashiTakaki, ShojiNegishi, YoshioKohno, Satoru
    • C07C51/58C07C53/50C07C59/315C07C59/64C07C67/00C07C69/33
    • C07C51/58C07C59/64C07C53/50C07C59/315
    • 2,2,3-trifluoropropionyl fluoride is prepared by opening the tetrafluorooxethane ring in the presence of a catalyst. Analogously, a novel 2,2-difluoropropionic acid derivative of the formula:
      wherein X is chlorine, bromine, iodine, a group of the formula:
      or
      wherein R 1 and R 2 are each an aliphatic or halogenated aliphatic hydrocarbon group having 1 to 8 carbon atoms or an aromatic hydrocarbon group having 6 to 8 carbon atoms optionally bearing at least one substituent, or a group of the formula:
      wherein X , is fluorine, chlorine, bromine, iodine, the group of the formula: R,O- or R 2 COO-; and Y is fluorine, a group of the formula:
      wherein R 3 is an aliphatic or halogenated aliphatic hydrocarbon group having 1 to 8 carbon atoms except a perfluorohydrocarbon group or an aromatic hydrocarbon group having 6 to 8 carbon atoms optionally bearing at least one substituent, or a group of the formula
      wherein R f is an aliphatic perfluorohydrocarbon having 1 to 7 carbon atoms is prepared.
    • 通过在催化剂存在下打开四氟氧杂环乙烷环来制备2,2,3-三氟丙酰氟。 类似地,下式的新的2,2-二氟丙酸衍生物:其中X是氯,溴,碘,下式的基团:或其中R1和R2各自是具有1至8个碳原子的脂族或卤代脂族烃基 或任选带有至少一个取代基的具有6至8个碳原子的芳族烃基,或下式的基团:其中X 1为氟,氯,溴,碘,式R,O-或R 2 COO- ; Y是氟,下式的基团:其中R3是除全氟烃基或任选带有至少一个取代基的具有6至8个碳原子的芳族烃基之外具有1至8个碳原子的脂族或卤化脂族烃基,或 制备其中Rf为具有1至7个碳原子的脂族全氟烃的式的基团。