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1. 发明授权

EP2615525B1 Touch free operation of devices by use of depth sensors 有权转让
公开(公告)号：EP2615525B1
公开(公告)日：2019-05-15
申请号：EP13150837.6
申请日：2013-01-10
申请人： Biosense Webster (Israel) Ltd.
发明人： Merschon, Asaf , Govari, Assaf , Altmann, Andres Claudio , Schwartz, Yitzhack
IPC分类号： G06F3/01 , G06F3/03

2. 发明公开

EP2682774A1 Catheter with synthetic aperture MRI sensor 审中-公开
标题翻译： Katheter mit synthetischem Apertur-MRI-Sensor
公开(公告)号：EP2682774A1
公开(公告)日：2014-01-08
申请号：EP13174243.9
申请日：2013-06-28
申请人： Biosense Webster (Israel), Ltd.
发明人： Govari, Assaf , Altmann, Andres Claudio , Schwartz, Yitzhack , Ephrath, Yaron , Beeckler, Christopher Thomas
IPC分类号： G01R33/36 , A61B5/055 , G01R33/3415
CPC分类号： A61B5/055 , A61B5/0044 , A61B5/6852 , G01R33/3415 , G01R33/3621
摘要： A medical probe, including a flexible insertion tube having a distal end for insertion into a body cavity. An array of spatially separated coils is positioned within the distal end. A processor is configured to process respective signals generated by the coils in response to magnetic resonance of tissue in the body cavity, and to process the signals while applying a phase delay responsive to a separation between the coils so as to image the tissue.
摘要翻译：一种医疗探针，包括具有用于插入体腔的远端的柔性插入管。空间分离的线圈的阵列位于远端内。处理器被配置为响应于体腔中组织的磁共振来处理由线圈产生的相应信号，并且响应于线圈之间的间隔施加相位延迟来处理信号，以便对组织成像。

3. 发明公开

EP2591722A1 Integrative atrial fibrillation ablation 有权
标题翻译：综合偏振消融
公开(公告)号：EP2591722A1
公开(公告)日：2013-05-15
申请号：EP12192456.7
申请日：2012-11-13
申请人： Biosense Webster (Israel), Ltd.
发明人： Schwartz, Yitzhack
IPC分类号： A61B5/055 , A61B5/042 , A61B5/04 , A61B18/14 , A61B18/00 , A61B18/24 , A61N7/02 , A61B19/00
CPC分类号： A61B5/7285 , A61B5/0452 , A61B5/046 , A61B18/1492 , A61B18/24 , A61B34/20 , A61B34/25 , A61B2018/00357 , A61B2018/00577 , A61B2034/252 , A61B2090/065 , A61B2090/364 , A61N7/022
摘要： Cardiac tissue ablation is carried out by defining first regions containing first locations including ganglionated plexi in a heart of a living subject, and inserting a probe into the heart. The method is further carried out by detecting electrical activity in the heart via electrodes on the distal portion of the probe, defining second regions having second locations, wherein the electrical activity exhibits a dominant frequency that is higher than a predefined threshold, defining third regions having third locations, wherein the electrical activity exhibits complex fractionated atrial electrograms, constructing an electroanatomical map of the heart that defines intersections of the first regions and at least one of the second regions and the third regions, selecting ablation sites within the intersections, and ablating cardiac tissue at the ablation sites.
摘要翻译：通过在生物体的心脏中限定含有神经节丛的第一位置的第一区域，并将探针插入心脏来进行心脏组织消融。该方法还通过检测探针的远端部分上的电极来检测心脏中的电活动，限定具有第二位置的第二区域，其中电活动表现出高于预定阈值的主频率，限定第三区域具有第三位置，其中所述电活动显示复杂的分级心房电图，构建定义所述第一区域和所述第二区域和所述第三区域中的至少一个的交叉点的心脏的电解剖图，选择所述交叉路口内的消融部位，以及消融心脏消融部位的组织。

4. 发明公开

EP2559371A1 Transesophageal echocardiography capsule 有权转让
标题翻译：横纹藻Echokardiografie-Kapsel
公开(公告)号：EP2559371A1
公开(公告)日：2013-02-20
申请号：EP12182268.8
申请日：2011-06-22
申请人： Biosense Webster (Israel), Ltd. , Bar-Tal, Meir , Schwartz, Yitzhack , Amit, Mati
发明人： Bar-Tal, Meir , Schwartz, Yitzhack , Amit, Mati
IPC分类号： A61B1/00 , A61B1/04 , A61B1/273 , A61B8/12
CPC分类号： A61B1/00082 , A61B1/00101 , A61B1/00128 , A61B1/00154 , A61B1/00158 , A61B1/041 , A61B1/2733 , A61B8/12 , A61B8/4472
摘要： An imaging system, including a capsule, configured to enter an esophagus of a patient, having an ultrasonic transducer configured to image tissue of the patient. The system further includes an applicator tube configured to enter the esophagus, the tube being attachable to the capsule for positioning the capsule within the esophagus, and being detachable from the capsule after positioning of the capsule so as to permit the tube to be withdrawn from the esophagus while the capsule remains in position in the esophagus. The system further includes a capsule locator, fixedly connected to the capsule, comprising a first magnetic locating device providing a first signal, indicative of a first position of the capsule, in response to a magnetic field generated in a vicinity of the patient. The system further includes a probe comprising a second magnetic locating device providing a second signal, indicative of a second position of the probe in the patient and registered with the first position, in response to the magnetic field.
摘要翻译：一种包括胶囊的成像系统，其配置为进入患者的食道，具有配置成对患者的组织进行成像的超声波换能器。所述系统还包括构造成进入食道的施用管，所述管可附接到所述胶囊，以将所述胶囊定位在所述食道内，并且在所述胶囊定位之后可从所述胶囊中拆下以允许所述管从所述食管，同时胶囊保持在食道的位置。系统还包括固定地连接到胶囊的胶囊定位器，包括响应于在患者附近产生的磁场而提供指示胶囊的第一位置的第一信号的第一磁性定位装置。所述系统还包括探针，所述探针包括响应于所述磁场而提供第二信号的第二磁性定位装置，其指示所述探针在患者中的第二位置并且与所述第一位置对准。

5. 发明公开

EP2462867A1 Identifying critical cfae sites using contact measurement 有权转让
标题翻译：识别仪器仪表仪器仪表仪器仪表电子仪器仪表
公开(公告)号：EP2462867A1
公开(公告)日：2012-06-13
申请号：EP11192651.5
申请日：2011-12-08
申请人： Biosense Webster (Israel), Ltd.
发明人： Schwartz, Yitzhack
IPC分类号： A61B5/042 , A61B19/00
CPC分类号： A61B5/0422 , A61B5/6885 , A61B18/1492 , A61B34/20 , A61B34/30 , A61B2018/00351 , A61B2018/00577 , A61B2090/065 , A61B2090/067
摘要： A method for mapping includes receiving electrical inputs measured by a probe at respective locations in a chamber of a heart of a subject. The electrical inputs a r e processed to identify complex fractionated electrograms. At each of the respective locations, a respective contact quality between the probe and a tissue in the chamber is measured. A map of the complex fractionated electrograms in the chamber is created using the electrical inputs and the measured contact quality.
摘要翻译：一种用于映射的方法包括：在对象的心脏的腔室的相应位置处接收由探针测量的电输入。电输入被加工以识别复杂的分级电描记图。在各个位置的每个位置处，测量探针和腔室中的组织之间的相应接触质量。使用电气输入和测量的接触质量创建腔室中复杂分级电描记图。

6. 发明公开

EP2666415A3 Endobronchial catheter 有权转让
标题翻译： Endobronchialer Katheter
公开(公告)号：EP2666415A3
公开(公告)日：2015-02-18
申请号：EP13169004.2
申请日：2013-05-23
申请人： Biosense Webster (Israel), Ltd. , Waldstreicher, Jonathan Reuben , Krimsky, William Sanford , Schwartz, Yitzhack , Shalgi, Avi , Bar-Tal, Meir , Amit, Matityahu , Hayam, Gal , Itah, Refael
发明人： Waldstreicher, Jonathan Reuben , Krimskiy, William Sanford , Schwartz, Yitzhack , Shalgi, Avi , Bar-Tal, Meir , Amit, Matityahu , Hayam, Gal , Itah, Refael , Ainsworth, Robert D.
IPC分类号： A61B8/12 , A61B8/00 , A61M25/10 , A61B18/00 , A61B5/00 , A61B10/02 , A61M25/00 , A61B10/04
CPC分类号： A61B8/12 , A61B5/0538 , A61B5/062 , A61B5/063 , A61B5/4836 , A61B5/6853 , A61B8/08 , A61B8/0841 , A61B8/4254 , A61B8/4263 , A61B8/445 , A61B8/463 , A61B10/0233 , A61B10/04 , A61B18/1477 , A61B18/1492 , A61B2010/045 , A61B2017/00809 , A61B2017/3488 , A61B2018/00011 , A61B2018/00273 , A61B2018/00285 , A61B2018/00541 , A61B2018/00839 , A61B2018/00988 , A61B2018/1475 , A61B2034/2051 , A61B2090/3784 , A61M25/0082 , A61M25/04 , A61M2025/1052
摘要： An endobronchial probe includes a deflector having a bore extending therethrough at an angle to its long axis for passage of a tool. The probe includes a location sensor and an ultrasound imager. A push-pull anchoring system comprises a plurality of guides and wires that can extend beyond the guides and retract within the guides. When extended the wires diverge from the long axis sufficiently to engage a bronchus. The probe includes a balloon disposed on the distal segment contralateral to bore that when inflated urges the mouth of the bore into contact with the bronchial wall.
摘要翻译：支气管内探针包括偏转器，偏转器具有与其长轴成一定角度延伸的孔，用于通过工具。探头包括位置传感器和超声波成像器。推拉锚固系统包括多个引导件和电线，其可以延伸超过引导件并在引导件内缩回。当延长电线时，电线从长轴上足以与支气管接合。探针包括设置在对侧的远端段上的气囊，当膨胀时促使孔的口与支气管壁接触。

7. 发明公开

EP2399506A2 Transesophageal echocardiography capsule 审中-公开
标题翻译：横纹藻Echokardiografie-Kapsel
公开(公告)号：EP2399506A2
公开(公告)日：2011-12-28
申请号：EP11171056.2
申请日：2011-06-22
申请人： Biosense Webster (Israel), Ltd , Bar-Tal, Meir , Schwartz, Yitzhack , Amit, Mati
发明人： Bar-Tal, Meir , Schwartz, Yitzhack , Amit, Mati
IPC分类号： A61B1/00 , A61B1/04 , A61B1/273 , A61B8/12
CPC分类号： A61B1/00082 , A61B1/00101 , A61B1/00128 , A61B1/00154 , A61B1/00158 , A61B1/041 , A61B1/2733 , A61B8/12 , A61B8/4472
摘要： An imaging system, including a capsule, configured to enter an esophagus of a patient, having an ultrasonic transducer configured to image tissue of the patient. The system further includes an applicator tube configured to enter the esophagus, the tube being attachable to the capsule for positioning the capsule within the esophagus, and being detachable from the capsule after positioning of the capsule so as to permit the tube to be withdrawn from the esophagus while the capsule remains in position in the esophagus.
摘要翻译：一种包括胶囊的成像系统，其配置为进入患者的食道，具有配置成对患者的组织进行成像的超声波换能器。所述系统还包括构造成进入食道的施用管，所述管可附接到所述胶囊，以将所述胶囊定位在所述食道内，并且在所述胶囊定位之后可从所述胶囊中拆下以允许所述管从所述食管，同时胶囊保持在食道的位置。

8. 发明授权

EP2939627B1 CHECKING FOR PERFORATION OF THE EPICARDIUM USING MAGNETIC RESONANCE IMAGING 有权
标题翻译：穿孔外膜安装测试使用磁成像
公开(公告)号：EP2939627B1
公开(公告)日：2016-08-31
申请号：EP15165375.5
申请日：2015-04-28
申请人： Biosense Webster (Israel) Ltd.
发明人： Schwartz, Yitzhack , Govari, Assaf , Gliner, Vadim
IPC分类号： A61B90/00 , A61B5/0402 , A61B5/107 , A61B5/00 , A61B18/14 , A61B5/055
CPC分类号： A61B5/055 , A61B5/0402 , A61B5/1075 , A61B5/4836 , A61B18/1492 , A61B2090/374
摘要： Cardiac ablation is monitored to detect hemopericardium by iteratively acquiring magnetic resonance imaging (MRI) data that includes the pericardium, measuring the pericardium by analyzing the sets of MRI data, making a determination that a measurement of the pericardium in consecutive sets of MRI data differ, and responsively to the determination reporting a change in configuration of the pericardium.

9. 发明授权

EP2591722B1 Integrative atrial fibrillation ablation 有权
标题翻译：整体房颤消融
公开(公告)号：EP2591722B1
公开(公告)日：2014-12-24
申请号：EP12192456.7
申请日：2012-11-13
申请人： Biosense Webster (Israel), Ltd.
发明人： Schwartz, Yitzhack
IPC分类号： A61B5/055 , A61B5/042 , A61B18/14 , A61B18/24 , A61N7/02 , A61B19/00 , A61B5/0452
CPC分类号： A61B5/7285 , A61B5/0452 , A61B5/046 , A61B18/1492 , A61B18/24 , A61B34/20 , A61B34/25 , A61B2018/00357 , A61B2018/00577 , A61B2034/252 , A61B2090/065 , A61B2090/364 , A61N7/022

10. 发明公开

EP2666415A2 Endobronchial catheter 有权转让
标题翻译：支气管导管
公开(公告)号：EP2666415A2
公开(公告)日：2013-11-27
申请号：EP13169004.2
申请日：2013-05-23
申请人： Biosense Webster (Israel), Ltd. , Waldstreicher, Jonathan Reuben , Krimsky, William Sanford , Schwartz, Yitzhack , Shalgi, Avi , Bar-Tal, Meir , Amit, Matityahu , Hayam, Gal , Itah, Refael
发明人： Waldstreicher, Jonathan Reuben , Krimskiy, William Sanford , Schwartz, Yitzhack , Shalgi, Avi , Bar-Tal, Meir , Amit, Matityahu , Hayam, Gal , Itah, Refael , Ainsworth, Robert D.
IPC分类号： A61B8/12 , A61B8/00 , A61M25/10 , A61B18/00 , A61B5/00 , A61B10/02 , A61M25/00 , A61B10/04
CPC分类号： A61B8/12 , A61B5/0538 , A61B5/062 , A61B5/063 , A61B5/4836 , A61B5/6853 , A61B8/08 , A61B8/0841 , A61B8/4254 , A61B8/4263 , A61B8/445 , A61B8/463 , A61B10/0233 , A61B10/04 , A61B18/1477 , A61B18/1492 , A61B2010/045 , A61B2017/00809 , A61B2017/3488 , A61B2018/00011 , A61B2018/00273 , A61B2018/00285 , A61B2018/00541 , A61B2018/00839 , A61B2018/00988 , A61B2018/1475 , A61B2034/2051 , A61B2090/3784 , A61M25/0082 , A61M25/04 , A61M2025/1052
摘要： An endobronchial probe includes a deflector having a bore extending therethrough at an angle to its long axis for passage of a tool. The probe includes a location sensor and an ultrasound imager. A push-pull anchoring system comprises a plurality of guides and wires that can extend beyond the guides and retract within the guides. When extended the wires diverge from the long axis sufficiently to engage a bronchus. The probe includes a balloon disposed on the distal segment contralateral to bore that when inflated urges the mouth of the bore into contact with the bronchial wall.

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