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1. 发明公开

EP3527245A1 MULTIPLE USE DISPOSABLE INJECTION PEN 审中-实审
公开(公告)号：EP3527245A1
公开(公告)日：2019-08-21
申请号：EP19164693.4
申请日：2012-03-15
申请人： Becton, Dickinson and Company
发明人： Cronenberg, Richard , Quinn, Michael
IPC分类号： A61M5/20 , A61M5/315
摘要： A medication injection pen (11) includes a housing (1) and a dose set knob (2) rotatable with respect to the housing (1). A brake assembly (68) is disposed in the housing (1) and has a ratchet member (43). A driver (21) includes at least one external tooth (57) engaging the ratchet member (43). The engagement between the ratchet member (43) and the at least one external tooth (57) substantially prevents the driver (21) from rotating with respect to the dose set knob (2) during dose setting and dose correcting. The engagement between the ratchet member (43) and the at least one external tooth (57) allows the driver (21) to rotate with the dose set knob (2) during an injection.

2. 发明公开

EP3050587A1 MEDICAL INJECTOR WITH ROTATABLE RATCHETING PLUNGER 有权转让
标题翻译： MEDISINISCHER INJEKTOR MIT ROTIERBAREM SPERRKLINKENKOLBEN
公开(公告)号：EP3050587A1
公开(公告)日：2016-08-03
申请号：EP16158107.9
申请日：2011-03-17
申请人： Becton Dickinson and Company
发明人： Cronenberg, Richard , Wu, Haiming
IPC分类号： A61M5/315
CPC分类号： A61M5/3158 , A61M5/1782 , A61M5/24 , A61M5/31553 , A61M5/31555 , A61M5/31581
摘要： A medical injector (152) has a body (154) with a displaceable plunger (164). The plunger (164) includes a plurality of spaced-apart ratchet teeth (168) disposed along the length thereof. At least one indexer (176) is provided to engage the plunger (164), wherein the indexer (176) is configured to allow the plunger (164) to displace distally toward a distal end of the body (154) but not proximally toward a proximal end of the body (154). The medical injector (152) also includes an actuator (158) having an engagement portion (178) formed to engage one or more of the ratchet teeth (168). The actuator (158) is displaceable to a ready state, the engagement portion (178) being displaced proximally relative to the plunger (164) with the actuator (158) being displaced to the ready state. The indexer (176) prevents proximal movement of the plunger (164), thereby allowing the engagement portion (178) to bypass one or more of the ratchet teeth (168) with the actuator (158) being displaced to the ready state. In addition, the actuator (158) is displaceable from the ready state to cause actuation of the medical injector (152). The displacement from the ready state causes distal displacement of the engagement portion (178) with the engagement portion (178) engaging one or more of the ratchet teeth (168) and causing distal displacement of the plunger (164) with the engagement portion (178). The plunger (164) is slidably displaceable relative to the body (154), and rotatable relative to the body (154) to selectively engage and disengage ratchet teeth (168) engaged with the indexer (176) and the actuator (158).
摘要翻译：医疗注射器（152）具有带有可移位柱塞（164）的主体（154）。柱塞164包括沿其长度设置的多个间隔开的棘轮齿168。提供至少一个分度器（176）以接合柱塞（164），其中分度器（176）构造成允许柱塞（164）朝向主体（154）的远端向远侧移动，但不向近侧朝向主体主体（154）的近端。医疗注射器（152）还包括具有形成为接合一个或多个棘齿（168）的接合部分（178）的致动器（158）。致动器（158）可移动到就绪状态，接合部分（178）相对于柱塞（164）向近侧位移，致动器（158）移动到就绪状态。分度器（176）防止柱塞（164）的近端运动，从而允许接合部分（178）绕过一个或多个棘轮齿（168），致动器（158）移动到就绪状态。另外，致动器（158）可从就绪状态移位以引起医用注射器（152）的致动。从就绪状态的位移导致接合部分（178）的远端位移与接合部分（178）接合一个或多个棘轮齿（168）并且引起柱塞（164）与接合部分（178）的远侧位移）。柱塞164相对于主体154可滑动地移动，并且可相对于主体154旋转以选择性地接合和脱离与分度器176和致动器158接合的棘轮齿168。

3. 发明授权

EP3375468B1 MEDICAL INJECTOR WITH RATCHETING PLUNGER 有权
公开(公告)号：EP3375468B1
公开(公告)日：2019-11-20
申请号：EP18169323.5
申请日：2011-03-17
申请人： Becton, Dickinson and Company
发明人： Cronenberg, Richard
IPC分类号： A61M5/00 , A61M5/315

4. 发明授权

EP3323449B1 MULTIPLE USE DISPOSABLE INJECTION PEN 有权
公开(公告)号：EP3323449B1
公开(公告)日：2019-07-03
申请号：EP17210309.5
申请日：2012-03-15
申请人： Becton, Dickinson and Company
发明人： Cronenberg, Richard , Quinn, Michael
IPC分类号： A61M5/20 , A61M5/24 , A61M5/315

5. 发明公开

EP2606927A2 Cartridge for containing and dispensing a medicament 有权转让
标题翻译：用于容纳和分配药物的药筒
公开(公告)号：EP2606927A2
公开(公告)日：2013-06-26
申请号：EP13150403.7
申请日：2010-12-03
申请人： Becton, Dickinson and Company, Inc.
发明人： Cronenberg, Richard , Vedrine, Lionel , Begley, Patrick
IPC分类号： A61M5/24 , A61M5/31
摘要： A cartridge (100) for containing and dispensing a medicament, the cartridge (100) including a cartridge body (104) having an interior cavity (108) therein, a stopper (112) movably disposed within the interior cavity (108), and a septum (116, 148) disposed at an opposite end of the interior cavity (108) from the stopper (112), for containing the medicament within the interior cavity (108). The cartridge (100) also includes a connection thread (120) integrally formed as a unitary construction of the cartridge body (104), the thread (120) being disposed at a first end of the cartridge body (104) for connecting a pen needle directly to the cartridge body (104) to pierce the septum (116, 148) and provide communication between the medicament and a patient end of the pen needle. The cartridge (100) additionally includes a connector (128) for directly connecting the cartridge body (104) to a dosing mechanism for moving the stopper (112) toward the septum (116, 148) to dispense the medicament.
摘要翻译：一种用于容纳和分配药剂的药筒（100），所述药筒（100）包括其中具有内腔（108）的药筒主体（104），可移动地设置在所述内腔（108）内的塞子（112）设置在所述内腔（108）的与所述塞子（112）相对的端部处的隔膜（116,148），用于将所述药物容纳在所述内腔（108）内。所述盒（100）还包括一体形成为所述盒体（104）的整体结构的连接螺纹（120），所述螺纹（120）设置在所述盒体（104）的第一端，用于连接笔针（104）直接刺穿隔膜（116,148）并提供药物与笔针的患者端之间的连通。药筒（100）还包括用于将药筒本体（104）直接连接到用于使塞子（112）朝向隔膜（116,148）移动以分配药剂的定量供给机构的连接器（128）。

6. 发明公开

EP4410330A2 MULTIPLE USE DISPOSABLE INJECTION PEN 审中-公开
公开(公告)号：EP4410330A2
公开(公告)日：2024-08-07
申请号：EP24181357.5
申请日：2012-03-15
申请人： Becton, Dickinson and Company
发明人： Cronenberg, Richard , Quinn, Michael
IPC分类号： A61M5/24
CPC分类号： A61M5/31535 , A61M5/31551 , A61M5/31575 , A61M5/31585 , A61M2005/240720130101 , A61M2005/315220130101 , A61M2205/58120130101 , A61M2205/58220130101 , A61M5/31541 , A61M5/31528
摘要： A medication injection pen (51) includes a housing (1) and a dose set knob (2) having at least one internal tooth (22). A brake member (5) has a plurality of axially extending splines (52). A driver or setback member (9) includes at least one external tooth (92) engaging the at least one internal tooth (22) of the dose set knob (2) and at least one ratchet arm (96) engaging the plurality of axially extending splines (52). The driver (9) is prevented from rotating with the dose set knob (2) while moving axially with the dose set knob (2) during dose setting and dose correcting, and the driver (9) rotates with the dose set knob (2) during an injection.

7. 发明公开

EP3964251A1 END OF INJECTION INDICATOR FOR INJECTION PEN 审中-实审
公开(公告)号：EP3964251A1
公开(公告)日：2022-03-09
申请号：EP21204003.4
申请日：2012-03-16
申请人： Becton, Dickinson and Company
发明人： Cronenberg, Richard , Quinn, Michael , Shetty, Gautam
IPC分类号： A61M5/20 , A61M5/315
摘要： A medication injection pen (50) includes a housing (1) and a dose set knob (2) rotatably connected to the housing (1) for setting a dose. An indicator member (200) is movable between a visible position indicating a zero position of the dose set knob (2) and a non-visible position indicating a non-zero position of the dose set knob (2). The indicator member is visible to a user in the visible position and not visible to the user in the non-visible position. The dose set knob is in the zero position when a set dose has been completely administered. Accordingly, a visible indication is provided to the user when a set dose has been completely administered.

8. 发明授权

EP2606927B1 Cartridge for containing and dispensing a medicament 有权转让
公开(公告)号：EP2606927B1
公开(公告)日：2020-02-05
申请号：EP13150403.7
申请日：2010-12-03
申请人： Becton, Dickinson and Company
发明人： Cronenberg, Richard , Vedrine, Lionel , Begley, Patrick
IPC分类号： A61M5/24 , A61M5/31

9. 发明公开

EP3375468A1 MEDICAL INJECTOR WITH RATCHETING PLUNGER 有权
公开(公告)号：EP3375468A1
公开(公告)日：2018-09-19
申请号：EP18169323.5
申请日：2011-03-17
申请人： Becton, Dickinson and Company
发明人： Cronenberg, Richard
IPC分类号： A61M5/00 , A61M5/315
摘要： A medical injector (10) including a body (32) having a distal end and a proximal end, and a plunger (12) displaceably disposed in the body (32). The plunger (12) includes a plurality of spaced-apart ratchet teeth (20) disposed along the length thereof. The plunger (12) selectively displaces a stopper to dispense a medicament from said medical injector (10). The medical injector (10) also includes an indexer (38) disposed within the body (32) to engage the plunger (12) to permit distal displacement of the plunger (12) and substantially prevent proximal displacement of the plunger (12), an actuator (48) having an engagement portion (50) to engage the plunger (12) to permit proximal displacement of the actuator (48) relative to the plunger (12) and substantially prevent distal displacement of the actuator (48) relative to the plunger (12), and a rotating member (48B) for proximally displacing the engagement portion (50) relative to the plunger (12) and the body (32). Upon proximal displacement of the actuator (48) relative to the body (32) to a ready state, one or more of the ratchet teeth (20) bypass the engagement portion (50) to proximally displace the actuator (48) relative to the plunger (12). Upon distal displacement of the actuator (48) relative to the body (32) from the ready state, the actuator (48) engages one or more of the ratchet teeth (20) to distally displace the plunger (12) relative to the indexer (38) to distally displace the stopper to dispense medicament from the medical injector (10).

10. 发明公开

EP3251714A1 MEDICAL INJECTOR WITH ROTATABLE RATCHETING PLUNGER 有权
标题翻译：带可旋转棘轮的医疗注射器
公开(公告)号：EP3251714A1
公开(公告)日：2017-12-06
申请号：EP17178475.4
申请日：2011-03-17
申请人： Becton, Dickinson and Company
发明人： Cronenberg, Richard , Wu, Haiming
IPC分类号： A61M5/315
CPC分类号： A61M5/3158 , A61M5/1782 , A61M5/24 , A61M5/31553 , A61M5/31555 , A61M5/31581
摘要： A medical injector (152) has a body (154) with a displaceable plunger (164). The plunger (164) includes a plurality of spaced-apart ratchet teeth (168) disposed along the length thereof. At least one indexer (176) is provided to engage the plunger (164), wherein the indexer (176) is configured to allow the plunger (164) to displace distally toward a distal end of the body (154) but not proximally toward a proximal end of the body (154). The medical injector (152) also includes an actuator (158) having an engagement portion (178) formed to engage one or more of the ratchet teeth (168). The actuator (158) is displaceable to a ready state, the engagement portion (178) being displaced proximally relative to the plunger (164) with the actuator (158) being displaced to the ready state. The indexer (176) prevents proximal movement of the plunger (164), thereby allowing the engagement portion (178) to bypass one or more of the ratchet teeth (168) with the actuator (158) being displaced to the ready state. In addition, the actuator (158) is displaceable from the ready state to cause actuation of the medical injector (152). The displacement from the ready state causes distal displacement of the engagement portion (178) with the engagement portion (178) engaging one or more of the ratchet teeth (168) and causing distal displacement of the plunger (164) with the engagement portion (178). The plunger (164) is slidably displaceable relative to the body (154), and rotatable relative to the body (154) to selectively engage and disengage ratchet teeth (168) engaged with the indexer (176) and the actuator (158).
摘要翻译：医用注射器（152）具有带可移动柱塞（164）的主体（154）。柱塞（164）包括沿其长度设置的多个间隔开的棘齿（168）。提供至少一个分度器（176）以接合柱塞（164），其中分度器（176）构造成允许柱塞（164）朝向主体（154）的远端向远侧移位，但不朝近侧（154）的近端。医用注射器（152）还包括致动器（158），该致动器具有形成为接合一个或多个棘轮齿（168）的接合部分（178）。致动器158可移位至准备状态，接合部分178在致动器158移位至准备状态的情况下相对于柱塞164向近侧移位。分度器（176）防止柱塞（164）向近侧移动，由此允许接合部分（178）绕过一个或多个棘轮齿（168），其中致动器（158）移位到准备状态。另外，致动器（158）可从准备状态移位以引起医用注射器（152）的致动。从就绪状态的位移导致接合部分178与接合部分178接合一个或多个棘齿168的远侧移位并导致柱塞164与接合部分178的远侧位移）。柱塞164相对于本体154可滑动地移动，并且可相对于本体154旋转以选择性地接合和脱离与分度器176和致动器158接合的棘轮齿168。

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