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1. 发明公开

EP2578185A3 Adjustable intraocular lens 审中-公开
标题翻译：可调眼内透镜
公开(公告)号：EP2578185A3
公开(公告)日：2013-07-24
申请号：EP12007086.7
申请日：2009-04-03
申请人： BATTELLE MEMORIAL INSTITUTE , THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
发明人： Mcginniss, Vincent D. , Roberts, Cynthia J. , Risser, Steven M.
IPC分类号： A61F2/16 , A61L27/50
CPC分类号： A61F2/1627 , A61F2/1635 , A61F2/1659 , A61F2002/16965 , A61L27/50 , A61L2430/16 , G02B1/043
摘要： Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.

2. 发明公开

EP2578185A2 Adjustable intraocular lens 审中-公开
标题翻译：可调节的人工晶状体
公开(公告)号：EP2578185A2
公开(公告)日：2013-04-10
申请号：EP12007086.7
申请日：2009-04-03
申请人： BATTELLE MEMORIAL INSTITUTE , THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
发明人： Mcginniss, Vincent D. , Roberts, Cynthia J. , Risser, Steven M.
IPC分类号： A61F2/16 , A61L27/50
CPC分类号： A61F2/1627 , A61F2/1635 , A61F2/1659 , A61F2002/16965 , A61L27/50 , A61L2430/16 , G02B1/043
摘要： Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.
摘要翻译：公开了用于改变透镜（例如眼内透镜）的功率的方法和装置。在一种方法中，镜片包含含有可交联侧基的单一聚合物基质，其中聚合物基质在交联时体积增加。镜片不含游离单体。在暴露于紫外线辐射下时，交联引起透镜的暴露部分体积增大，导致折射率增加。在另一种方法中，镜片包含含有可光漂白发色团的聚合物基质。在暴露于紫外线辐射下时，光漂白导致暴露部分的折射率降低，透镜厚度没有任何变化。这些方法避免了等待扩散发生以改变透镜形状并且避免需要第二次暴露于辐射以锁定透镜的变化。

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