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1. 发明授权

EP2848984B1 Methods and apparatus for ophthalmic devices including cycloidally oriented liquid crystal layers 有权
公开(公告)号：EP2848984B1
公开(公告)日：2018-12-05
申请号：EP14185223.6
申请日：2014-09-17
申请人： Johnson & Johnson Vision Care, Inc.
发明人： De Sio, Luciano , Flitsch, Frederick A. , Pandojirao-s, Praveen , Pugh, Randall Braxton , Riall, James Daniel , Serak, Svetlana , Tabirian, Nelson V. , Toner, Adam , Uskova, Olena
IPC分类号： G02C7/04 , G02C7/08 , A61F2/16 , G02F1/1337 , G02F1/01 , G02C7/10
CPC分类号： G02C7/049 , A61F2/1624 , A61F2/1627 , A61F2/1635 , A61F2/1648 , A61F2002/1696 , A61F2210/0076 , G02C7/04 , G02C7/041 , G02C7/083 , G02C7/101 , G02C7/12 , G02C2202/16 , G02C2202/18 , G02F1/133753
摘要： This invention discloses methods and apparatus for providing a variable optic insert into an ophthalmic lens. A liquid crystal layer may be used to provide a variable optic function and in some examples, an alignment layer for the liquid crystal layer may be patterned in a cycloidally dependent manner. The patterning may allow for a polarization dependent lens in some examples. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some examples, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control optical characteristics.

2. 发明公开

EP3363792A1 COMPOUNDS CONTAINING SI ATOMS FOR OPTICALLY ACTIVE DEVICES 审中-公开
公开(公告)号：EP3363792A1
公开(公告)日：2018-08-22
申请号：EP17156331.5
申请日：2017-02-15
申请人： Merck Patent GmbH
发明人： The designation of the inventor has not yet been filed
IPC分类号： C07D311/12 , A61F2/14 , C07D407/04 , G02B1/04 , C07D405/04 , C07D409/04 , C07F7/18
CPC分类号： C07D407/04 , A61F2/1627 , C07D311/12 , C07D405/04 , C07D409/04 , C07F7/1804 , C08L83/04 , G02B1/041 , G02B1/043
摘要： The present invention relates to novel 2-oxo-2H-chromen compounds, particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for compositions and ophthalmic devices as well as to compositions and ophthalmic devices comprising such compounds.

3. 发明授权

EP3211026B1 ON-DEMAND PHOTOINITIATED POLYMERIZATION 有权
公开(公告)号：EP3211026B1
公开(公告)日：2018-06-27
申请号：EP17166946.8
申请日：2011-07-06
申请人： California Institute of Technology
发明人： BOYDSTON, Andrew J. , GRUBBS, Robert H. , DAEFFLER, Chris , MOMCILOVIC, Nebojsa
IPC分类号： C08J7/00 , C08J3/24 , C08J7/18 , C08J3/28 , A61F2/16
CPC分类号： A61K9/0051 , A61F2/14 , A61F2/1624 , A61F2/1627 , C08F22/14 , C08F120/14 , C08G77/38 , C08J3/24 , C08J3/28 , C08J2333/00 , G02B1/043 , G02C7/022 , C08L83/04 , C08L33/08 , C08L33/10
摘要： An intraocular implant is provided. The intraocular implant comprises a matrix material, and a composition comprising a masking compound and a prepolymer. The masking compound is capable of blocking polymerization or crosslinking of the prepolymer, until photoisomerization of the compound is triggered, and the compound is converted from a first isomer to a second isomer having a different absorption profile. The prepolymer is a composition that can undergo a polymerization or crosslinking reaction upon photoinitiation

4. 发明公开

EP3209252A4 INTRA-OCULAR DEVICE 审中-公开
公开(公告)号：EP3209252A4
公开(公告)日：2018-04-18
申请号：EP15852556
申请日：2015-10-22
申请人： VERILY LIFE SCIENCES LLC
发明人： CONRAD ANDREW JASON
IPC分类号： A61F9/007 , A61F2/16
CPC分类号： A61F2/1627 , A61F2/1648 , A61F9/007 , A61F2002/1682 , A61F2002/16901 , A61F2250/0001 , A61F2250/0002
摘要： An intra-ocular device includes an electronic lens that can be controlled to control the overall optical power of the device. The device can be installed within a flexible polymeric material shaped to conform to the inside surface of a lens capsule of an eye. Accommodation forces applied to the device and/or polymeric material via the lens capsule can cause a change in the optical power of the device and/or polymeric material. Further, such accommodation forces can be detected by an accommodation sensor of the device and the optical power of the electronic lens can be controlled based on the detected accommodation forces. Operated in this way, the device and polymeric material can restore a degree of accommodation to the eye that is related to existing mechanisms for controlling such accommodation, i.e., forces exerted by the eye via the lens capsule.

5. 发明授权

EP2609455B1 NEGATIVE ADD LIQUID MENISCUS LENS 有权
标题翻译：负添加液体半透膜镜片
公开(公告)号：EP2609455B1
公开(公告)日：2017-09-27
申请号：EP11764625.7
申请日：2011-08-16
申请人： Johnson & Johnson Vision Care Inc.
发明人： PUGH, Randall, B. , OTTS, Daniel, B. , TONER, Adam , KERNICK, Edward, R. , RIALL, James, Daniel , SNOOK, Sharika
IPC分类号： G02B7/04 , G02B1/06 , G02B3/12 , G02B3/14 , G02C7/04 , G02C7/08 , A61F2/16
CPC分类号： G02B1/06 , A61F2/1627 , A61F2/1635 , G02B3/12 , G02B3/14 , G02B7/04 , G02C7/04 , G02C7/085

6. 发明公开

EP3092525A4 METHOD AND APPARATUS FOR CREATION AND ELECTRICAL TUNING OF SPATIALLY NON-UNIFORM REFLECTION OF LIGHT 审中-公开
标题翻译： VERFAHREN UND VORRICHTUNG ZUR ERZEUGUNG UND ELEKTRISCHEN ABSTIMMUNG VONRÄUMLICHUNGLEICHMÄSSIGERREFLEXION VON LICHT
公开(公告)号：EP3092525A4
公开(公告)日：2017-06-28
申请号：EP15735422
申请日：2015-01-12
申请人： UNIVERSITÉ LAVAL
发明人： GALSTIAN TIGRAN
IPC分类号： G02F1/01 , G02C7/04 , G02F1/13 , G02F1/19 , H02S40/22
CPC分类号： G02F1/19 , A61F2/1627 , G02C7/04 , G02C7/083 , G02C7/12 , G02C7/14 , G02F1/061 , G02F1/13306 , G02F1/1334 , G02F1/133553 , G02F1/13363 , G02F1/1337 , G02F1/134309 , G02F1/134327 , G02F1/13471 , G02F1/137 , G02F1/29 , G02F2001/13775 , G02F2001/294 , G02F2203/18 , H01L31/0547 , H01S3/0071 , H01S3/08059 , H01S3/105 , H04N5/23287 , H04N5/23296 , Y02E10/52

7. 发明公开

EP2943156A4 ADJUSTABLE TORIC INTRAOCULAR LENS 审中-公开
标题翻译：可调式散光隐形眼镜
公开(公告)号：EP2943156A4
公开(公告)日：2016-09-07
申请号：EP14738265
申请日：2014-01-10
申请人： PHILLIPS ANDREW F
发明人： PHILLIPS ANDREW F
IPC分类号： A61F2/16
CPC分类号： A61F2/1627 , A61F2/1629 , A61F2/1645 , A61F9/00804 , A61F9/00821 , A61F9/00827 , A61F2002/1681 , A61F2250/0006

8. 发明公开

EP3040052A1 AN OPTICAL LENS 有权转让
标题翻译： OPTISCHE LINSE
公开(公告)号：EP3040052A1
公开(公告)日：2016-07-06
申请号：EP16150681.1
申请日：2013-10-09
申请人： Perfect IP, LLC
发明人： Sahler, Ruth , Zhou, Stephen Q. , Bille, Josef F.
IPC分类号： A61F2/16 , B29D11/00 , B29C71/04
CPC分类号： A61F2/16 , A61F2/1613 , A61F2/1627 , A61F2/1648 , A61F9/008 , A61F9/00834 , B29C71/04 , B29C2035/0838 , B29C2791/009 , B29D11/00125 , B29K2995/0092
摘要： An optical lens comprising synthetic polymeric materials is disclosed. The optical lens further comprises a plurality of optical zones formed within a predetermined region of a polymeric material (PLM) having a UV absorber, said plurality of optical zones created using a lens formation method that increases the hydrophilicity of only said predetermined region of said PLM. The method comprises, generating a pulsed laser radiation output from a laser source having a wavelength selected to interact with PLM including said UV absorber, within said predetermined region of said PLM; accepting said pulsed laser radiation into a numerical aperture within a microscope objective to produce a focused laser radiation output; transmitting said focused laser radiation output to said predetermined region within said PLM to increase the hydrophilicity of said predetermined region of said PLM; exposing said optical zones to water; and allowing said predetermined region of said PLM to absorb water to form a lens within said predetermined region of said PLM.
摘要翻译：公开了包含合成聚合物材料的光学透镜。所述光学透镜还包括形成在具有紫外线吸收剂的聚合物材料（PLM）的预定区域内的多个光学区域，所述多个光学区域使用增加所述PLM的所述预定区域的亲水性的透镜形成方法。该方法包括：在所述PLM的所述预定区域内产生从激光源输出的脉冲激光辐射，所述激光源选择为与包括所述UV吸收剂的PLM相互作用的波长; 将所述脉冲激光辐射接收到显微镜物镜内的数值孔径中以产生聚焦的激光辐射输出; 将所述聚焦激光辐射输出传输到所述PLM内的所述预定区域以增加所述PLM的所述预定区域的亲水性; 将所述光学区域暴露于水中; 并且允许所述PLM的所述预定区域吸收水以在所述PLM的所述预定区域内形成透镜。

9. 发明公开

EP3040051A1 HYDROPHILICITY ALTERATION METHOD 有权转让
标题翻译： VERFAHREN ZURÄNDERUNGDER HYDROPHILIE
公开(公告)号：EP3040051A1
公开(公告)日：2016-07-06
申请号：EP16150680.3
申请日：2013-10-09
申请人： Perfect IP, LLC
发明人： Sahler, Ruth , Zhou, Stephen, Q. , Bille, Josef F.
IPC分类号： A61F2/16 , B29D11/00 , B29C71/04
CPC分类号： A61F2/16 , A61F2/1613 , A61F2/1627 , A61F2/1648 , A61F9/008 , A61F9/00834 , B29C71/04 , B29C2035/0838 , B29C2791/009 , B29D11/00125 , B29K2995/0092
摘要： A method for increasing the hydrophilicity of only an internal region of a polymeric material (PM) having a UV absorber is disclosed. The method comprises generating a pulsed laser radiation output from a laser source having a wavelength selected to interact with said UV absorber within said internal region of said PM, distributing said pulsed laser radiation output across an input area of a microscope objective; accepting said distributed pulsed radiation into a numerical aperture within said microscope objective to produce a focused laser radiation output; transmitting said focused laser radiation output to said internal region within said PM to increase the hydrophilicity of said internal region of said PM; exposing said internal region to water; and allowing said PM to absorb water thus reducing the refractive index of said internal region of said PM.
摘要翻译：公开了一种增加仅具有UV吸收剂的聚合物材料（PM）的内部区域的亲水性的方法。该方法包括产生从激光源输出的脉冲激光辐射，所述激光源具有被选择为与所述PM的所述内部区域内的所述UV吸收剂相互作用的波长，将所述脉冲激光辐射输出分布在显微镜物镜的输入区域上; 将所述分布式脉冲辐射接收到所述显微镜物镜内的数值孔径中以产生聚焦的激光辐射输出; 将所述聚焦激光辐射输出传输到所述PM内的所述内部区域，以增加所述PM的所述内部区域的亲水性; 将所述内部区域暴露于水中; 并且允许所述PM吸收水，从而降低所述PM的所述内部区域的折射率。

10. 发明授权

EP2713950B1 METHOD FOR MODIFYING THE REFRACTIVE INDEX OF AN OPTICAL MATERIAL AND RESULTING OPTICAL VISION COMPONENT 有权转让
标题翻译：一种改进光学材料折射率的方法及其光学视觉元件
公开(公告)号：EP2713950B1
公开(公告)日：2015-08-19
申请号：EP12724845.8
申请日：2012-05-29
申请人： The University Of Rochester
发明人： KNOX, Wayne, H. , JANI, Dharmendra, M. , DING, Li
IPC分类号： A61F2/16 , A61F9/008 , A61L27/52
CPC分类号： G02B3/0087 , A61F2/1618 , A61F2/1627 , A61F9/00834 , A61L27/16 , A61L27/50 , A61L27/52 , A61L2400/18 , A61L2430/16 , G02B2003/0093 , G02C2202/12 , G02C2202/14 , C08L33/10
摘要： A method for modifying the refractive index of an optical polymeric material. The method comprises continuously irradiating predetermined regions of an optical, polymeric material with femtosecond laser pulses to form a gradient index refractive structure within the material. An optical device includes an optical, polymeric lens material having an anterior surface and posterior surface and an optical axis intersecting the surfaces and at least one laser-modified, GRIN layer disposed between the anterior surface and the posterior surface and arranged along a first axis 45° to 90° to the optical axis, and further characterized by a variation in index of refraction across at least one of at least a portion of the adjacent segments and along each segment.

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