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1. 发明授权

EP1532210B1 RYLENFARBSTOFFE 有权
标题翻译：苯染料
公开(公告)号：EP1532210B1
公开(公告)日：2006-11-22
申请号：EP03797212.2
申请日：2003-07-25
申请人： BASF Aktiengesellschaft , Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
发明人： KRIEGER, Matthias , BÖHM, Arno , SIGGEL, Lorenz , BECKER, Stefan , MÜLLEN, Klaus , KOHL, Christopher
IPC分类号： C09B57/08
CPC分类号： C09B5/62
摘要： Disclosed are rylene dyes of general formula (I), in which R represents hydrogen, optionally substituted C1-C30 alkyl, C5-C8 cycloalkyl, aryl, or hetaryl, R' represents bromine, cyano, -NR 2, optionally substituted aryloxy, arylthio, hetaryloxy, or hetarylthio, optionally substituted C3-C18 alk-1-inyl, X and Y both represent hydrogen or jointly represent a radical of formula (Ia), n represents 2, 3, 4, or additionally 1 if X and Y represent a radical of formula (Ia), n' represents 1 to 4, and m represents 0 to 6.

2. 发明授权

EP1206456B1 THERMOCHROME RYLENFARBSTOFFE 有权
公开(公告)号：EP1206456B1
公开(公告)日：2004-11-17
申请号：EP00958457.4
申请日：2000-08-16
申请人： BASF AKTIENGESELLSCHAFT , Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
发明人： BÖHM, Arno , SCHMEISSER, Heinrich , BECKER, Stefan , MÜLLER, Klaus
IPC分类号： C07D221/18 , C09B5/62
CPC分类号： C09B5/62
摘要： The invention relates to rylene dyes of the general formula (I), wherein the variables have the following meanings: R represents hydrogen; optionally substituted C1-C30 alkyl-C5-C8-cycloalkyl, aryl or hetaryl; R'represents optionally substituted C2-C30 alkyl or C5-C8 cycloalkyl, substituted methyl; and n is 0 or 1. The invention also relates to the preparation and use of said dyes for coloring highly molecular organic and inorganic materials and to 9-amino-perylene-3,4-dicarboxylic acid imides (Va) as their intermediate products.
摘要翻译：本发明涉及通式（I）的萘嵌苯染料，其中各变量具有以下含义：R表示氢; 任选取代的C 1 -C 30烷基-C 5 -C 8环烷基，芳基或杂芳基; R'表示任选取代的C 2 -C 30烷基或C 5 -C 8环烷基，取代的甲基; 并且n是0或1.本发明还涉及所述染料用于着色高分子量有机和无机材料和9-氨基 - 苝-3,4-二羧酸酰亚胺（Va）作为其中间产物的制备和用途。

3. 发明授权

EP1370612B1 THERMOCHROME RYLENFARBSTOFFE 有权
标题翻译：热致变色苯染料
公开(公告)号：EP1370612B1
公开(公告)日：2004-09-22
申请号：EP02718131.2
申请日：2002-02-14
申请人： BASF AKTIENGESELLSCHAFT , Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
发明人： BÖHM, Arno , KRIEGER, Matthias , BECKER, Stefan , MÜLLEN, Klaus
IPC分类号： C09B5/62 , C08K5/3437 , C09D11/00
CPC分类号： C09B5/62 , C07D221/18
摘要： The invention relates to rylene dyes of general formula (I), in which: R represents hydrogen or optionally substituted C1-C30 alkyl, aryl or heteroaryl; R' represents optionally substituted C2-C30 alkyl or C5-C8 cycloalkyl, or substituted methyl; n represents 0 or 1. The invention also relates to the production of said dyes, to the use thereof for colouring highly molecular organic and inorganic materials and to aminorylene-3,4-dicarboxylic acid imides IV as their intermediate products.

4. 发明公开

EP2367848A1 USE OF CONKUNITZIN-S1 FOR THE MODULATION OF GLUCOSE-INDUCED INSULIN SECRETION 审中-公开
标题翻译： CONKUNITZIN-S1的调制糖诱导INSULINSEZERNIERUNG的使用
公开(公告)号：EP2367848A1
公开(公告)日：2011-09-28
申请号：EP09804528.9
申请日：2009-08-10
申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. , Universität zu Lübeck
发明人： TERLAU, Heinrich , FINOL-URDANETA, Rocio , BECKER, Stefan , RAASCH, Walter
IPC分类号： C07K14/435
CPC分类号： C07K14/43504 , C07K14/8114
摘要： The present invention relates to a (poly)peptide or a peptidomimetic thereof having the biological activity of Conkunitzin-S1, wherein said (poly)peptide is selected from (a) a polypeptide comprising or having the amino acid sequence of SEQ ID NO: 1; (b) a polypeptide having at least 85% sequence identity to SEQ ID NO:1; or (c) a fragment of a) or b); wherein said (poly)peptide or peptidomimetic specifically modulates the activity of a channel having the activity of a Kv1.7 containing channel, for the treatment or prevention of metabolic diseases or conditions, or secondary diseases or conditions related to said metabolic diseases or conditions. The present invention furthermore relates to a method of screening for (poly)peptides derived from Conkunitzin-S1 suitable for specifically modulating the activity of a channel having the activity of a Kv1.7 containing channel, comprising: (a) altering the amino acid sequence of Conkunitzin-S1 represented by SEQ ID NO: 1 by deleting and/or inserting and/or replacing at least one amino acid; and (b) determining the modulatory effect of the (poly)peptide obtained in step (a) (i) on a channel having the activity of a Kv1.7 containing channel and (ii) on channels, preferably potassium channels, not having the activity of a Kv1.7 containing channel, which are optionally expressed on the same cell as the channel having the activity of a Kv1.7 containing channel; wherein a modulatory effect of the (poly)peptide determined in step (i) that is at least 50% of the modulatory effect of Conkunitzin-S1 indicates that the (poly)peptide re suitable for modulating the activity of said channel having the activity of a Kv1.7 containing channel; and wherein the determination of essentially no modulatory effect in step (ii) indicates that the (poly)peptide is specifically modulating the activity of channels having the activity of a Kv1.7 containing channel.

5. 发明授权

EP1311625B1 FUNKTIONALISIERTE PERYLENTETRACARBONSÄUREDIIMIDE 有权
标题翻译：官能perylenetetracarbimides
公开(公告)号：EP1311625B1
公开(公告)日：2006-02-01
申请号：EP01971909.5
申请日：2001-08-11
申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
发明人： BECKER, Stefan , KLOK, Harm-Anton , RODRIGUEZ-HERNANDEZ, Juan , SCHUCH, Falk , MÜLLEN, Klaus
IPC分类号： C09B69/00
CPC分类号： C07D471/06 , C08F4/00 , C08G63/6852 , C08K5/0041 , C09B5/62 , C09B69/102
摘要： The invention relates to the use of functionalized perylene-3, 4, 9, 10-tetracarboxylic acid diimides as initiators and/or as reaction partners for polymerization reactions, to polymers produced using perylene-3, 4, 9, 10-tetracarboxylic acid diimide compounds, to the use of these colored and/or fluorescent polymers, and to novel functionalized perylene tetracarboxylic acid diimides.

6. 发明公开

EP1874943A2 ENZYMATISCHE SYNTHESE VON POLY(OXYALKYLEN)ACRYLAMIDEN 有权
标题翻译：聚（氧化烯）丙烯酰胺的酶法合成
公开(公告)号：EP1874943A2
公开(公告)日：2008-01-09
申请号：EP06754774.5
申请日：2006-04-20
申请人： BASF AKTIENGESELLSCHAFT
发明人： HÄRING, Dietmar , HAUER, Bernhard , BECKER, Stefan
IPC分类号： C12P13/00 , C08G65/322 , C08F20/54
CPC分类号： C12P13/02 , C08F220/58 , C08F283/06 , C08G65/332 , C08G65/33324
摘要： The invention relates to a novel method for the enzymatic synthesis of poly(oxyalkylene)acrylamide as well as the use thereof for synthesizing polymers.

7. 发明公开

EP1532210A1 RYLENFARBSTOFFE 有权
公开(公告)号：EP1532210A1
公开(公告)日：2005-05-25
申请号：EP03797212.2
申请日：2003-07-25
申请人： BASF AKTIENGESELLSCHAFT , Max-Planck-Gesellschaft zur Förderungder Wissenschaften e.V.
发明人： KRIEGER, Matthias , BÖHM, Arno , SIGGEL, Lorenz , BECKER, Stefan , MÜLLEN, Klaus , KOHL, Christopher
IPC分类号： C09B57/08
CPC分类号： C09B5/62
摘要： Disclosed are rylene dyes of general formula (I), in which R represents hydrogen, optionally substituted C1-C30 alkyl, C5-C8 cycloalkyl, aryl, or hetaryl, R' represents bromine, cyano, -NR32, optionally substituted aryloxy, arylthio, hetaryloxy, or hetarylthio, optionally substituted C3-C18 alk-1-inyl, X and Y both represent hydrogen or jointly represent a radical of formula (Ia), n represents 2, 3, 4, or additionally 1 if X and Y represent a radical of formula (Ia), n' represents 1 to 4, and m represents 0 to 6.

8. 发明授权

EP1789462B1 VERFAHREN ZUR HERSTELLUNG VON (POLY-C2-C4-ALKYLENGLYKOL)-MONO(METH)ACRYLSÄUREESTERN 有权转让
标题翻译： VERFAHREN ZUR HERSTELLUNG VON（POLY-C2-C4-ALKYLENGLYKOL）-MONO（METH）ACRYLSÄUREESTERN
公开(公告)号：EP1789462B1
公开(公告)日：2008-02-20
申请号：EP05785644.5
申请日：2005-09-02
申请人： BASF Aktiengesellschaft
发明人： BECKER, Stefan , PASTRE, Jörg , PAKUSCH, Joachim , GÖTZ, Thomas , BUREK, Arnold , HANSCH, Wolfgang , SPILGER, Stefanie
IPC分类号： C08F290/06 , C07C69/54
CPC分类号： C08F299/065 , C08G65/3322
摘要： The invention relates to a method for producing (poly-C 2 -C 4 alkylene glycol)-monoacrylic esters and -monomethacrylic esters, and to a method for producing copolymers of such (poly-C 2 -C 4 alkylene glycol)-mono(meth)acrylic esters with acrylic ester or methacrylic ester and to the use of the polymers as liquefying additives in cement-containing preparations. The (poly-C 2 -C 4 alkylene glycol)-monoacrylic esters and -monomethacrylic esters are produced by reacting acrylic anhydride or methacrylic anhydride (referred to in the following as (meth)acrylic anhydride (A)) with at least one OH group-carrying poly-C 2 -C 4 alkylene glycol compound (P) in the presence of a base, said base being selected from the group of basic compounds that have, at 90° C, a solubility in the poly-C 2 -C 4 alkylene glycol compound (P) of not more than 10 g/l, the molar ratio of (meth)acrylic anhydride (A) to compound (P) (molar ratio (A):(P)) being in the range of from 1:1 to 1.095:1, preferably in the range of from 1.005:1 to 1.09:1, especially in the range of from 1.01:1 to 1.085:1 and most preferred in the range of from 1.02:1 to 1.08:1. The production of (meth)acrylic acid with (poly-C 2 -C 4 alkylene glycol)-mono(meth)acrylic esters comprises the following steps: i) production of a (poly-C 2 -C 4 alkylene glycol)mono(meth)acrylic ester by reacting (meth)acrylic anhydride (A) with at least one OH group-carrying poly-C 2 -C 4 alkylene glycol compound (P) in the presence of a base according to the inventive method, and ii) radical copolymerization of the (poly-C 2 -C 4 alkylene glycol)mono(meth)acrylic ester obtained in step i) with acrylic acid and/or methacrylic acid and optionally additional ethylenically unsaturated monomers.
摘要翻译：生产（聚C 2 -C 4亚烷基二醇） - 单（甲基）丙烯酸酯和单甲基丙烯酸酯的方法及其制备方法本发明涉及生产（聚C 2 -C 4亚烷基二醇） - 单（甲基）丙烯酸酯和单甲基丙烯酸酯的方法与丙烯酸酯或甲基丙烯酸酯的混合物以及该聚合物在含水泥制剂中作为液化添加剂的用途。（聚C 2 -C 4亚烷基二醇）单丙烯酸酯和单甲基丙烯酸酯通过使丙烯酸酐或甲基丙烯酸酐（以下称为（甲基）丙烯酸酐（A））与至少一个携带OH基团聚C 2 -C 4亚烷基二醇化合物（P）在碱的存在下反应，所述碱选自在90℃下在所述聚C 2 -C 4亚烷基二醇化合物中具有溶解度的碱性化合物（P ）不超过10g / l，（甲基）丙烯酸酐（A）与化合物（P）的摩尔比（摩尔比（A）：（P））为1：1至1.095： 1，优选1.005:1至1.09:1，特别是1.01:1至1.085:1，最优选1.02:1至1.08:1。（甲基）丙烯酸与（聚C 2 -C 4亚烷基二醇） - 单（甲基）丙烯酸酯的生产包括以下步骤：i）生产（聚C 2 -C 4亚烷基二醇）单（甲基）丙烯酸酯（甲基）丙烯酸酐（A）与至少一种带有OH基的聚C 2 -C 4亚烷基二醇化合物（P）在碱存在下根据本发明方法反应，和ii）（聚 -C 2 -C 4亚烷基二醇）单体（甲基）丙烯酸酯与丙烯酸和/或甲基丙烯酸以及任选另外的烯键式不饱和单体反应。

9. 发明公开

EP1206456A1 THERMOCHROME RYLENFARBSTOFFE 有权
标题翻译：热致变色苯染料
公开(公告)号：EP1206456A1
公开(公告)日：2002-05-22
申请号：EP00958457.4
申请日：2000-08-16
申请人： BASF AKTIENGESELLSCHAFT , Max-Planck-Gesellschaft zur Förderungder Wissenschaften e.V.
发明人： BÖHM, Arno , SCHMEISSER, Heinrich , BECKER, Stefan , MÜLLER, Klaus
IPC分类号： C07D221/18 , C09B5/62
CPC分类号： C09B5/62
摘要： The invention relates to rylene dyes of the general formula (I), wherein the variables have the following meanings: R represents hydrogen; optionally substituted C1-C30 alkyl-C5-C8-cycloalkyl, aryl or hetaryl; R'represents optionally substituted C2-C30 alkyl or C5-C8 cycloalkyl, substituted methyl; and n is 0 or 1. The invention also relates to the preparation and use of said dyes for coloring highly molecular organic and inorganic materials and to 9-amino-perylene-3,4-dicarboxylic acid imides (Va) as their intermediate products.

10. 发明公开

EP1789462A1 VERFAHREN ZUR HERSTELLUNG VON (POLY-C2-C4-ALKYLENGLYKOL)-MONO(METH)ACRYLSÄUREESTERN 有权转让
标题翻译：用于制备（POLY-C 2 -C 4亚烷基二醇）单（甲基）丙烯酸酯的
公开(公告)号：EP1789462A1
公开(公告)日：2007-05-30
申请号：EP05785644.5
申请日：2005-09-02
申请人： BASF Aktiengesellschaft
发明人： BECKER, Stefan , PASTRE, Jörg , PAKUSCH, Joachim , GÖTZ, Thomas , BUREK, Arnold , HANSCH, Wolfgang , SPILGER, Stefanie
IPC分类号： C08F290/06 , C07C69/54
CPC分类号： C08F299/065 , C08G65/3322
摘要： The invention relates to a method for producing (poly-C2-C4 alkylene glycol)-monoacrylic esters and -monomethacrylic esters, and to a method for producing copolymers of such (poly-C2-C4 alkylene glycol)-mono(meth)acrylic esters with acrylic ester or methacrylic ester and to the use of the polymers as liquefying additives in cement-containing preparations. The (poly-C2-C4 alkylene glycol)-monoacrylic esters and -monomethacrylic esters are produced by reacting acrylic anhydride or methacrylic anhydride (referred to in the following as (meth)acrylic anhydride (A)) with at least one OH group-carrying poly-C2-C4 alkylene glycol compound (P) in the presence of a base, said base being selected from the group of basic compounds that have, at 90° C, a solubility in the poly-C2-C4 alkylene glycol compound (P) of not more than 10 g/l, the molar ratio of (meth)acrylic anhydride (A) to compound (P) (molar ratio (A):(P)) being in the range of from 1:1 to 1.095:1, preferably in the range of from 1.005:1 to 1.09:1, especially in the range of from 1.01:1 to 1.085:1 and most preferred in the range of from 1.02:1 to 1.08:1. The production of (meth)acrylic acid with (poly-C2-C4 alkylene glycol)-mono(meth)acrylic esters comprises the following steps: i) production of a (poly-C2-C4 alkylene glycol)mono(meth)acrylic ester by reacting (meth)acrylic anhydride (A) with at least one OH group-carrying poly-C2-C4 alkylene glycol compound (P) in the presence of a base according to the inventive method, and ii) radical copolymerization of the (poly-C2-C4 alkylene glycol)mono(meth)acrylic ester obtained in step i) with acrylic acid and/or methacrylic acid and optionally additional ethylenically unsaturated monomers.

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