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1. 发明公开

EP3154557A1 ACELLULAR AMNION DERIVED THERAPEUTIC COMPOSITIONS 有权
标题翻译： VONAZELLULÄREMAMNION ABGELEITETE，THERAPEUTISCHE ZUSAMMENSETZUNGEN
公开(公告)号：EP3154557A1
公开(公告)日：2017-04-19
申请号：EP15810063.6
申请日：2015-06-15
申请人： Amnio Technology LLC
发明人： WERBER, Bruce , BEAUDRY, Christian , SUDDARTH, Terrell
IPC分类号： A61K35/44 , A61K35/48 , A61K35/12 , A61K9/16
CPC分类号： A61K35/50 , A61K8/982 , A61K35/28 , A61K35/35 , A61K35/44 , A61M2037/0061 , A61Q19/08 , A61K2300/00
摘要： Acellular amnion derived therapeutic compositions are described having a number of various compositional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic stems cells. The amniotic stem cells may be destroyed, and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized amniotic membrane particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.
摘要翻译：描述了具有许多各种组成实施方案的无细胞羊膜衍生治疗组合物。无细胞羊膜衍生的治疗组合物基本上没有活的或活性的羊膜干细胞。羊水干细胞可能被破坏，细胞和细胞碎片可以从无细胞羊膜来源的治疗组合物中去除。无细胞羊膜衍生的治疗组合物可以包含微粉化的羊膜膜颗粒和/或羊水。脱细胞羊膜衍生治疗组合物可以是与流体如血浆，盐水，羊水，其组合等组合的微粉化羊膜的分散体。可将无细胞羊膜衍生的治疗组合物与基质组分组合以形成复合物。来自非细胞羊膜的治疗组合物可以与包含活细胞如干细胞的组合物结合使用。

2. 发明公开

EP3242672A1 AMNION DERIVED THERAPEUTIC COMPOSITION AND PROCESS OF MAKING SAME 有权
标题翻译： AMNION派生的治疗组合物及其制备方法
公开(公告)号：EP3242672A1
公开(公告)日：2017-11-15
申请号：EP15877280.6
申请日：2015-09-14
申请人： Amnio Technology LLC
发明人： WERBER, Bruce , BEAUDRY, Christian , SUDDARTH, Terrell
IPC分类号： A61K35/50 , A61K38/19 , A61K38/18 , A61K31/728
CPC分类号： A61K35/50 , A61K8/982 , A61K35/28 , A61K35/35 , A61K35/44 , A61M2037/0061 , A61Q19/08 , A61K2300/00
摘要： Acellular amnion derived therapeutic compositions are described having a number of various com positional embodiments. An acellular amnion derived therapeutic composition has essentially no live or active amniotic cells. The amniotic cells may be destroyed and the cells and cell debris may be removed from the acellular amnion derived therapeutic composition. An acellular amnion derived therapeutic composition may comprise micronized placental tissue particles, and/or amniotic fluid. An acellular amnion derived therapeutic composition may be a dispersion of micronized amniotic membrane combined with a fluid, such as plasma, saline, amniotic fluid, combinations thereof and the like. An acellular amnion derived therapeutic composition may be combined with a matrix component to form a composite. An acellular amnion derived therapeutic composition may be used in conjunction with a composition comprising viable cells, such as stem cells.

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