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1. 发明授权

EP0843573B1 ULTRASONIC BONE THERAPY APPARATUS 失效
标题翻译： DEVICE骨疗法利用超声
公开(公告)号：EP0843573B1
公开(公告)日：2003-12-10
申请号：EP95937426.5
申请日：1995-10-04
申请人： ORTHOLOGIC CORP.
发明人： KAUFMAN, Jonathan, J. , CHIABRERA, Allessandro, E.
IPC分类号： A61N1/00 , A61N7/00
CPC分类号： A61N7/00 , A61B2017/0015 , A61B2017/00172 , A61F2002/2864

2. 发明公开

EP1265578A2 CONTROL DEVICE FOR THE THERAPEUTIC MOBILIZATION OF JOINTS 有权
标题翻译：控制装置接头的疗效动员
公开(公告)号：EP1265578A2
公开(公告)日：2002-12-18
申请号：EP01913449.3
申请日：2001-03-14
申请人： Orthologic Corp.
发明人： SOLOMON, Alexander, G. , CULHANE, Jeffrey, J. , COTTERELL, Daniel, E., C.
IPC分类号： A61H1/02
CPC分类号： A61H1/0218 , A61H1/02 , A61H1/0277 , A61H2201/0173 , A61H2201/5007
摘要： A control system is adapted for use in association with a therapeutic motion and splinting device. The therapeutic device has at least one component that is monitored. The system comprises the steps of defining the range of motion, defining the maximum reverse on load, monitoring the reverse on load and moving the device through its range of motion. A first and second maximum limit of range of motion in a first and second direction are respectively defined. A maximum reverse on load is defined and is monitored whereby the deformation of the at least one component is monitored and the load created is interpreted. The device is cycled between a first and second position defined by one of the first maximum limit and the maximum reverse on load and one of the second maximum limit and the maximum reverse on load respectively.

3. 发明公开

EP0481761A3 Medical treatment device 失效
标题翻译：医疗处理装置及方法
公开(公告)号：EP0481761A3
公开(公告)日：1992-05-20
申请号：EP91309538.6
申请日：1991-10-16
申请人： OrthoLogic Corp.
发明人： Lamond, Donald R. , Heinzelman, Bert
IPC分类号： A61N2/00
CPC分类号： A61N2/02 , A61G13/0045 , A61G13/12 , A61G13/1235 , A61G13/124 , A61G13/1245
摘要： A medical treatment device (20) is disclosed which includes a medical treatment element (36,38) and resilient securing members (32,34) which adjust or deform to conform to the particular dimensions of that part of the patient's anatomy which is to be treated. The resilient securing members (32, 34) move or deform outwardly away from the patient (22) as the device is applied to conform to the size of the patient and ensure that the patient is centered within the treatment device. The medical treatment elements (36,38) are thus accurately positioned with respect to the patient (22). This is particularly important in treatments involving the application of magnetic fields to the patient (22). In addition, the disclosed medical device (20) is relatively comfortable and can be worn by a patient (22) for a relatively long period of time. The invention also extends to the method of applying the medical treatment device (20) to the patient (22).

4. 发明公开

EP2268304A2 METHODS FOR TREATING ACUTE MYOCARDIAL INFARCTION 审中-公开
标题翻译：方法治疗急性心肌梗死
公开(公告)号：EP2268304A2
公开(公告)日：2011-01-05
申请号：EP09750910.3
申请日：2009-03-26
申请人： Orthologic Corp.
发明人： STEER, Randolph, C. , SHELLER, Michael, R. , WAGSTAFF, John, D.
IPC分类号： A61K38/48 , A61K38/10 , A61P9/10
CPC分类号： A61K38/4833
摘要： The present invention includes methods of treating acute myocardial infarction in a subject, comprising administering to the subject a therapeutically effective amount of a non-proteolytically activated thrombin receptor agonist.

5. 发明公开

EP1009286A4 ULTRASONIC BONE ASSESSMENT METHOD AND APPARATUS 失效
标题翻译：方法和设备对骨骼的研究利用超声
公开(公告)号：EP1009286A4
公开(公告)日：2000-06-21
申请号：EP97940810
申请日：1997-09-04
申请人： ORTHOLOGIC CORP
发明人： CHIABRERA ALESSANDRO , KAUFMAN JONATHON J
IPC分类号： A61B8/08
CPC分类号： A61B8/0875
摘要： A method for the assessment of various properties of bone is provided. The method includes applying a pair of ultrasound transducers to skin on opposite sides of the bone and generating an ultrasound signal, and directing the signal through both the bone and a known medium to obtain a bone output singal and a reference signal. The method further includes establishing a set of parameters associated with the bone output signal and a set of parameters associated with the reference signal, and then subjeting the two sets of parameters to comparative analysis in order to obtain the desired bone property. An apparatus for the assessment of various properties of bone is also provided. The apparatus includes a pair of ultrasound transducers (16, 18) which may be single element transducers or array transducers in any combination. The apparatus further includes various computer hardware components (20, 22) and computer software (34) for generating and directing the ultrasound signal, establishing the parameter sets and performing the comparative analysis.

6. 发明公开

EP0863737A1 CONTINUOUS PASSIVE MOTION DEVICES FOR JOINTS 失效
标题翻译： DEVICE器关节的连续被动运动
公开(公告)号：EP0863737A1
公开(公告)日：1998-09-16
申请号：EP96937150.0
申请日：1996-11-14
申请人： ORTHOLOGIC CORP.
发明人： SARINGER, John, H. , CULHANE, Jeffrey, J.
IPC分类号： A61H1
CPC分类号： A61H1/0266 , A61H1/0285
摘要： The present invention provides continuous passive motion (CPM) devices for joints. An ankle CPM device includes a lower leg support attached at its lower end to a semi-circular track. An actuator slides along the track and can be locked in any desired position on the track. A shaft is pivotally connected at one end thereof to the actuator and a shoe is attached at the other end thereof. When the actuator is positioned at the bottom of the track, the ankle joint of the patient undergoes inversion/eversion motion. When the motor housing is rotated 90° and positioned near the top of the track plantar/dorsi, flexion movement is obtained. A combination of both types of joint movement are obtained for the actuator in intermediate positions. A wrist CPM device includes a brace for the forearm attached to a semi-circular track on which an actuator is mounted. A hand grip is mounted on a semi-circular bracket and a shaft extends between the actuator and a coupling slidably mounted on the semi-circular bracket. With the actuator positioned below the forearm, when the actuator pivots the shaft the wrist joint undergoes ulnar/radial deviation movement and when the motor is rotated 90° and positioned at the side of the arm, extension/flexion movement of the wrist joint is obtained. Positioning the actuator in intermediate positions produces a wrist movement which is a combination of extension/flexion and ulnar/radial deviation of the wrist joint.

7. 发明公开

EP2280722A2 METHOD OF TREATING DEGENERATIVE DISEASES 审中-公开
标题翻译：方法治疗退化性疾病的
公开(公告)号：EP2280722A2
公开(公告)日：2011-02-09
申请号：EP09724276.2
申请日：2009-03-24
申请人： Orthologic Corp.
发明人： CARNEY, Darrell, H. , STEER, Randolph, C.
IPC分类号： A61K38/48 , A61P25/16 , A61P27/02
CPC分类号： A61K38/4833
摘要： Agonists of a non-proteolytically activated receptor can be used in methods for treating a disease or disorder in a subject. The methods comprise administering to the subject a therapeutically effective amount of an agonist, wherein the disease or disorder is scleroderma, macular degeneration, diabetic retinopathy, Huntington's disease, Parkinson's disease, closed head trauma, glaucoma, optic neuritis or allograft vasculopathy.

8. 发明授权

EP1539800B1 THROMBIN PEPTIDE DERIVATIVE DIMERS 有权
标题翻译：凝血酶肽的二聚体
公开(公告)号：EP1539800B1
公开(公告)日：2007-05-23
申请号：EP03763062.1
申请日：2003-07-01
申请人： Orthologic Corp.
发明人： CARNEY, Darrell, H.
IPC分类号： C07K5/00 , C07K5/10 , A61K38/00 , A61K38/16
CPC分类号： C12N9/6429 , A61K38/00 , C12Y304/21005
摘要： Disclosed are thrombin peptide derivative dimers comprising two polypeptides having the amino acid sequence SEQ ID NO. 2: Arg-Gly-Asp-Ala-Cys-Glu-Gly-Asp-Ser-Gly-Gly-Pro-Phe-Val, or a C-terminal truncated fragment of the polypeptide having at least six amino acids. Zero, one, two, or three amino acids in the polypeptide or polypeptide fragment differ from the corresponding position of SEQ ID NO. 2. Also disclosed are methods of treating a subject in need of treatment with a thrombin receptor agonist. The methods comprise the step of administering an effective amount of the thrombin peptide derivative described above.

9. 发明公开

EP1289470A2 COMBINATION PRO/SUPINATION AND FLEXION THERAPEUTIC MOBILIZATION DEVICE 审中-公开
标题翻译：治疗仪对于联合PRO /旋后屈曲
公开(公告)号：EP1289470A2
公开(公告)日：2003-03-12
申请号：EP01913450.1
申请日：2001-03-14
申请人： Orthologic Corp.
发明人： CULHANE, Jeffrey, J. , SOLOMON, Alexander, G. , KRUGER, Paul , MILOSAVLJEVIC, Dragan , COTTERELL, Daniel, E., C. , MACPHAIL, Andrew, J.
IPC分类号： A61H1/02
CPC分类号： A61H1/0277 , A61H2001/0203 , A61H2001/0207 , A61H2201/0173 , A61H2201/018
摘要： A therapeutic mobilization device includes a flexion assembly, a pro/supination assembly and a valgus carrying angle compensation device. The flexion assembly has an arm attachment assembly and an elbow actuator and the elbow actuator defines and axes of rotation. The pro/supination assembly is attached to flexion assembly and has a distal forearm attachment assembly and a pro/supination actuator operably connected thereto. The valgus carrying angle compensation device is operably attached to the flexion assembly and the pro/supination assembly. Preferably the pro/supination assembly is slidably mounted on a housing shaft whereby during flexion the pro/supination assembly is free to move along the housing shaft. Further, preferably the arm attachment assembly includes an attachment ring and an adjustable clamp pivotally attached thereto whereby the attachment ring defines a pro/supination axis and the adjustable clamp pivots orthogonally to the pro/supination axis.

10. 发明授权

EP0863737B1 CONTINUOUS PASSIVE MOTION DEVICES FOR JOINTS 失效
标题翻译： DEVICE器关节的连续被动运动
公开(公告)号：EP0863737B1
公开(公告)日：2000-09-13
申请号：EP96937150.9
申请日：1996-11-14
申请人： ORTHOLOGIC CORP.
发明人： SARINGER, John, H. , CULHANE, Jeffrey, J.
IPC分类号： A61H1/02
CPC分类号： A61H1/0266 , A61H1/0285
摘要： The present invention provides continuous passive motion (CPM) devices for joints. An ankle CPM device includes a lower leg support attached at its lower end to a semi-circular track. An actuator slides along the track and can be locked in any desired position on the track. A shaft is pivotally connected at one end thereof to the actuator and a shoe is attached at the other end thereof. When the actuator is positioned at the bottom of the track, the ankle joint of the patient undergoes inversion/eversion motion. When the motor housing is rotated 90 DEG and positioned near the top of the track plantar/dorsi, flexion movement is obtained. A combination of both types of joint movement are obtained for the actuator in intermediate positions. A wrist CPM device includes a brace for the forearm attached to a semi-circular track on which an actuator is mounted. A hand grip is mounted on a semi-circular bracket and a shaft extends between the actuator and a coupling slidably mounted on the semi-circular bracket. With the actuator positioned below the forearm, when the actuator pivots the shaft the wrist joint undergoes ulnar/radial deviation movement and when the motor is rotated 90 DEG and positioned at the side of the arm, extension/flexion movement of the wrist joint is obtained. Positioning the actuator in intermediate positions produces a wrist movement which is a combination of extension/flexion and ulnar/radial deviation of the wrist joint.

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