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    • 5. 发明公开
    • POLYLACTIC ACID AND METHOD FOR PRODUCING THE SAME
    • 聚乳酸及其制备方法
    • EP2058351A1
    • 2009-05-13
    • EP07792136.9
    • 2007-08-01
    • Teijin Engineering LtdMusashino Chemical Laborarory Ltd.
    • SUZUKI, HirotakaTAKADA, Masayuki
    • C08G63/08C08G63/90C08L101/16
    • C08G63/08C08G63/78C08G63/90C08L67/04C08L2205/02C08L2666/18
    • A method of producing a stereocomplex polylactic acid having a high melting point and a high molecular weight, wherein only stereocomplex crystals are grown even when melting and crystallization are repeated. The method comprises the steps of:
      (1) obtaining a first polylactic acid by the ring-opening polymerization of a first lactide composed of lactic acid units of the same chirality;
      (2) obtaining a purified first polylactic acid by removing the lactide from the first polylactic acid in a molten state under reduced pressure;
      (3) obtaining a second polylactic acid by the ring-opening polymerization of a second lactide which differs from the first lactide in chirality in the presence of the purified first polylactic acid; and
      (4) obtaining a purified second polylactic acid by removing the lactide from the second polylactic acid in a molten state under reduced pressure.
    • 生产具有高熔点和高分子量的立体络合物聚乳酸的方法,其中即使在重复熔融和结晶时也仅生长立体络合物晶体。 该方法包括以下步骤:(1)通过由相同手性的乳酸单元组成的第一丙交酯的开环聚合获得第一聚乳酸; (2)通过在减压下从熔融状态的第一聚乳酸中除去丙交酯而获得纯化的第一聚乳酸; (3)通过在纯化的第一聚乳酸存在下在手性中与第一丙交酯不同的第二丙交酯的开环聚合获得第二聚乳酸; 和(4)通过在减压下从熔融状态的第二聚乳酸中除去丙交酯来获得纯化的第二聚乳酸。
    • 8. 发明公开
    • PROCESS FOR PRODUCING D-ALANINE
    • VERFAHREN ZUR HERSTELLUNG VON D-ALANIN
    • EP1435392A1
    • 2004-07-07
    • EP02765541.4
    • 2002-09-13
    • Musashino Chemical Laborarory Ltd.
    • UEDA, Hiroyuki
    • C12P41/00C12R1/685C12R1/67C12R1/66C12R1/785
    • C12P41/001C12P13/06
    • This invention is characterized by having filamentous fungi act on a DL-alanine containing solution and assimilate L-alanine without by-producing pyruvic acid. The D-alanine can be produced efficiently because the filamentous fungi can be conveniently and easily separated from the fermentation broth and the fermentation broth contains no pyruvic acid. For the purpose of isolating the D-alanine from the separating solution, it suffices to treat the separating solution by the use of an ion exchange resin. The filamentous fungi effectively usable herein belong to at least one member selected from the class consisting of genus Aspergillus, genus Penicillium, genus Mucor, genus Rhizopus, genus Circinella, genus Cladosporium, genus Trichoderma, genus Eurotium, genus Chaetomium, genus Aureobasidium, genus Geotrichum, and genus Paecilomyces which are commercially available.
    • 本发明的特征在于具有丝状真菌作用于含有DL-丙氨酸的溶液并吸收L-丙氨酸而不产生丙酮酸。 可以有效地生产D-丙氨酸,因为丝状真菌可以方便地容易地从发酵液中分离出来,发酵液不含丙酮酸。 为了从分离溶液中分离出D-丙氨酸,可以使用离子交换树脂处理分离溶液。 本文中有效使用的丝状真菌属于选自曲霉属,青霉属,毛霉属,根霉属,根际属,枝孢霉属,木霉属,金龟子属,毛壳菌属,金银菌属,地热属 ,以及可商购的拟青霉属。