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1. 发明公开

EP2772537A1 POLYOL OXIDASE 有权
标题翻译：多元醇氧化酶
公开(公告)号：EP2772537A1
公开(公告)日：2014-09-03
申请号：EP12843544.3
申请日：2012-10-26
申请人： National University Corporation Kagawa University , Izumoring Co. Ltd. , Matsutani Chemical Industry Co., Ltd.
发明人： ASADA, Yasuhiko , IZUMORI, Ken
IPC分类号： C12N9/04 , C12P19/02 , C12N15/09
CPC分类号： C12N9/0006 , C12P19/02 , C12R1/80
摘要： Problem: To provide a novel polyol oxidase. Solution: A polyol oxidase, which is derived from a microorganism belonging to the genus Penicillium and is specified by the properties listed in the following (a) to (e): (a) it has a stable pH of 6.0 or higher and an optimum reaction pH of from 7.0 to 9.0; (b) it has an operating temperature of 50°C or lower and an optimum reaction temperature of 40°C; (c) it has a molecular weight of about 113 kDa; (d) it specifically recognizes the structure of a polyol in which the OH groups at positions 2 and 3 are in the L-erythro configuration and reacts with the polyol, but cannot recognize the structure of a polyol in which the OH group at position 4 is in the L-ribo configuration and does not react with the polyol; and (e) it has substrate specificity for D-arabitol, erythritol, D-mannitol, and D-sorbitol, which are listed in descending order of specificity.
摘要翻译：问题：提供一种新型的多元醇氧化酶。解决方案：一种多元醇氧化酶，来自属于青霉属的微生物，由下列（a）至（e）中列出的特性指定：（a）它具有6.0或更高的稳定pH值和最佳反应pH值为7.0至9.0; （b）工作温度为50°C或更低，最佳反应温度为40°C; （c）它具有约113kDa的分子量; （d）具体地确认了2位和3位的OH基为L-赤型构型并与多元醇反应的多元醇的结构，但是不能识别其中位置4处的OH基团处于L-核糖构型并且不与多元醇反应; 和（e）它对D-阿拉伯糖醇，赤藓糖醇，D-甘露糖醇和D-山梨醇具有底物特异性，按特异性的降序列出。

2. 发明公开

EP2772537A4 POLYOL OXIDASE 有权
标题翻译： POLYOLOXIDASE
公开(公告)号：EP2772537A4
公开(公告)日：2015-08-05
申请号：EP12843544
申请日：2012-10-26
申请人： UNIV KAGAWA NAT UNIV CORP , IZUMORING CO LTD , MATSUTANI KAGAKU KOGYO KK
发明人： ASADA YASUHIKO , IZUMORI KEN
IPC分类号： C12N9/04 , C12N15/09 , C12P19/02
CPC分类号： C12N9/0006 , C12P19/02 , C12R1/80

3. 发明公开

EP2730652A4 ENZYME PRODUCED BY ARTHROBACTER GLOBIFORMIS 有权转让
标题翻译： OFF节-GLOBIFORMIEN产生的酶
公开(公告)号：EP2730652A4
公开(公告)日：2015-07-29
申请号：EP12807548
申请日：2012-07-05
申请人： MATSUTANI KAGAKU KOGYO KK , IZUMORING CO LTD
发明人： IZUMORI KEN , GULLAPALLI PUSHPA KIRAN , SHINTANI TOMOYA , KIKKAWA RYO
IPC分类号： C12N9/90 , C12P19/02 , C12P19/24
CPC分类号： C12N9/90 , C12P19/02 , C12P19/24

4. 发明公开

EP2944691A4 KETOSE 3-EPIMERASE PRODUCED BY ARTHROBACTER GLOBIFORMIS 审中-公开
标题翻译： BY球形节杆菌生产酮糖3-差向异构酶
公开(公告)号：EP2944691A4
公开(公告)日：2016-08-24
申请号：EP13870446
申请日：2013-12-26
申请人： MATSUTANI KAGAKU KOGYO KK , IZUMORING CO LTD
发明人： IZUMORI KEN , GULLAPALLI PUSHPA KIRAN , SHINTANI TOMOYA , KIKKAWA RYO
IPC分类号： C12N9/90 , C12N15/09 , C12P19/02 , C12P19/24
CPC分类号： C12P19/24 , C12N9/90 , C12N11/00 , C12P19/02 , C12Y503/01
摘要： There are provided a highly safe epimerase usable in food industry, and a method for producing a ketose. The epimerase is a ketose 3-epimerase obtainable from a microorganism of the genus Arthrobacter , and having the amino acid sequence represented by SEQ ID NO: 1 of the Sequence Listing, and (1) substrate specificity whereby a D- or L-ketose is epimerized at position 3 to produce a corresponding D- or L-ketose, and (2) the highest substrate specificity for D-fructose and D-psicose among D- and L-ketoses. The ketose 3-epimerase is also represented by SEQ ID NO: 3 or SEQ ID NO: 4 of the Sequence Listing, and epimerizes a D- or L-ketose at position 3 to produce a corresponding D- or L-ketose.

5. 发明公开

EP2537422A1 Lifespan extending agent 有权转让
标题翻译： Wirkstoff zurVerlängerungder Lebensdauer
公开(公告)号：EP2537422A1
公开(公告)日：2012-12-26
申请号：EP12173112.9
申请日：2012-06-22
申请人： National University Corporation Kagawa University , Matsutani Chemical Industry Co., Ltd. , Izumoring Co. Ltd.
发明人： Sato, Masashi , Okuma, Kazuhiro , Izumori, Ken
IPC分类号： A23L1/22 , A23L1/236 , A23L1/30 , A61K31/7004 , A61P3/04 , A61P43/00
CPC分类号： A61K31/7004 , A23L2/60 , A23L5/00 , A23L21/00 , A23L27/33 , A23L29/30 , A23L33/10 , A23L33/125 , A23V2002/00 , A23V2200/302 , A23V2250/60
摘要： A lifespan extending agent that is safe for animals, and can easily be ingested in a form that resembles foods. A lifespan extending method is also disclosed. In the lifespan extending agent, a rare sugar usable as a sweetener is contained as an active ingredient.
摘要翻译：一种对动物安全的寿命延长剂，可以容易地以类似食物的形式摄入。还公开了寿命延长方法。在寿命延长剂中，含有作为甜味剂使用的稀有糖作为活性成分。

6. 发明公开

EP2944691A1 KETOSE 3-EPIMERASE PRODUCED BY ARTHROBACTER GLOBIFORMIS 审中-公开
标题翻译： DURCH ARTHROBACTER GLOBIFORMIS HERGESTELLTE KETOSE-3-EPIMERASE
公开(公告)号：EP2944691A1
公开(公告)日：2015-11-18
申请号：EP13870446.5
申请日：2013-12-26
申请人： Matsutani Chemical Industry Co., Ltd. , Izumoring Co., Ltd.
发明人： IZUMORI, Ken , GULLAPALLI, Pushpa Kiran , SHINTANI, Tomoya , KIKKAWA, Ryo
IPC分类号： C12N9/90 , C12N15/09 , C12P19/02
CPC分类号： C12P19/24 , C12N9/90 , C12N11/00 , C12P19/02 , C12Y503/01
摘要： There are provided a highly safe epimerase usable in food industry, and a method for producing a ketose. The epimerase is a ketose 3-epimerase obtainable from a microorganism of the genus Arthrobacter , and having the amino acid sequence represented by SEQ ID NO: 1 of the Sequence Listing, and (1) substrate specificity whereby a D- or L-ketose is epimerized at position 3 to produce a corresponding D- or L-ketose, and (2) the highest substrate specificity for D-fructose and D-psicose among D- and L-ketoses. The ketose 3-epimerase is also represented by SEQ ID NO: 3 or SEQ ID NO: 4 of the Sequence Listing, and epimerizes a D- or L-ketose at position 3 to produce a corresponding D- or L-ketose.
摘要翻译：提供了可用于食品工业的高度安全的差向异构酶，以及生产酮糖的方法。差向异构酶是从节杆菌属的微生物获得并具有由序列表的SEQ ID NO：1表示的氨基酸序列的酮糖3-差向异构酶，和（1）底物特异性，其中D-或L-酮糖是在位置3差向异构化以产生相应的D-或L-酮糖，和（2）D和L-酮糖之中D-果糖和D-灵芝蛋白的最高底物特异性。酮基3-差向异构酶也由序列表的SEQ ID NO：3或SEQ ID NO：4表示，并且在3位差异化D-或L-酮糖以产生相应的D-或L-酮糖。

7. 发明授权

EP2537422B1 Lifespan extending agent 有权转让
标题翻译：药物以延长寿命
公开(公告)号：EP2537422B1
公开(公告)日：2015-10-21
申请号：EP12173112.9
申请日：2012-06-22
申请人： National University Corporation Kagawa University , Matsutani Chemical Industry Co., Ltd. , Izumoring Co. Ltd.
发明人： Sato, Masashi , Okuma, Kazuhiro , Izumori, Ken
IPC分类号： A23L1/22 , A23L1/236 , A23L1/30 , A61K31/7004 , A61P3/04 , A61P43/00 , A23L2/60 , A23L1/09
CPC分类号： A61K31/7004 , A23L2/60 , A23L5/00 , A23L21/00 , A23L27/33 , A23L29/30 , A23L33/10 , A23L33/125 , A23V2002/00 , A23V2200/302 , A23V2250/60
摘要： A lifespan extending agent that is safe for animals, and can easily be ingested in a form that resembles foods. A lifespan extending method is also disclosed. In the lifespan extending agent, a rare sugar usable as a sweetener is contained as an active ingredient.

8. 发明公开

EP2730652A1 ENZYME PRODUCED BY ARTHROBACTER GLOBIFORMIS 有权转让
标题翻译： AUS ARTHROBACTER-GLOBIFORMIEN HERGESTELLTES ENZYM
公开(公告)号：EP2730652A1
公开(公告)日：2014-05-14
申请号：EP12807548.8
申请日：2012-07-05
申请人： Matsutani Chemical Industry Co., Ltd. , Izumoring Co. Ltd.
发明人： IZUMORI, Ken , GULLAPALLI, Pushpa Kiran , SHINTANI, Tomoya , KIKKAWA, Ryo
IPC分类号： C12N9/90 , C12P19/02
CPC分类号： C12N9/90 , C12P19/02 , C12P19/24
摘要： Task: There are provided a highly safe epimerase usable in food industry, and a method for producing a ketose. Resolution: The epimerase is a ketose 3-epimerase obtainable from a microorganism of the genus Arthrobacter, and having (1) substrate specificity whereby a D- or L-ketose is epimerized at position 3 to produce a corresponding D- or L-ketose, and (2) the highest substrate specificity for D-fructose and D-psicose among D- and L-ketoses.
摘要翻译：任务：提供了可用于食品工业的高度安全的差向异构酶，以及生产酮糖的方法。分辨率：差向异构酶是可从节杆菌属微生物获得的酮糖3-差向异构酶，并具有（1）底物特异性，其中D-或L-酮糖在3位差向异构化以产生相应的D-或L-酮糖，和（2）D和L-酮糖中D-果糖和D-灵芝蛋白的底物特异性最高。

9. 发明授权

EP2156751B8 NOVEL SWEETENER HAVING SUGAR-LIKE TASTE AND PRODUCTION METHOD AND USE OF THE SAME 有权转让
公开(公告)号：EP2156751B8
公开(公告)日：2018-11-14
申请号：EP08751758.7
申请日：2008-05-19
申请人： Matsutani Chemical Industry Co., Ltd. , National University Corporation Kagawa University , Izumoring Co., Ltd. , Hayashibara Co., Ltd.
发明人： OKUMA, Kazuhiro , YAMADA, Koji , TSUKUDA, Koji , IIDA, Tetsuo , OGA, Hiroshi , IZUMORI, Ken , TSUJISAKA, Yoshio , SHIMONISHI, Tsuyoshi , YAMADA, Takako , OKAMOTO, Iwao
IPC分类号： A23L5/00 , A23L33/125 , A23L2/60 , A61K31/7004 , A23L29/30 , A23L27/30
CPC分类号： A23L5/00 , A23L2/60 , A23L21/00 , A23L27/33 , A23L29/30 , A23L33/125 , A23V2002/00 , A61K31/7004 , A23V2250/61 , A23V2250/606 , A23V2250/628 , A23V2250/032 , A23V2200/15 , A23V2200/132
摘要： Problem: To develop a method for producing a novel sweetener containing glucose, fructose, and psicose, which is produced from glucose liquid sugar using an isomerase and an epimerase; use of the novel sweetener as a food or drink material; and a novel sweetener capable of preventing obesity caused by the intake thereof. Means of Resolution: An isomerase and an epimerase are allowed to act on glucose liquid sugar produced in a glucose liquid sugar production plant to thereby produce D-psicose, thereby providing a novel sweetener (product) that maintains the degree and quality of sweetness of a glucose-fructose mixed solution and never causes obesity, a method for producing the same, and use of the same.

10. 发明授权

EP2730652B1 ENZYME PRODUCED BY ARTHROBACTER GLOBIFORMIS 有权转让
标题翻译：由拟杆菌产生的酶
公开(公告)号：EP2730652B1
公开(公告)日：2017-09-06
申请号：EP12807548.8
申请日：2012-07-05
申请人： Matsutani Chemical Industry Co., Ltd. , Izumoring Co., Ltd.
发明人： IZUMORI, Ken , GULLAPALLI, Pushpa Kiran , SHINTANI, Tomoya , KIKKAWA, Ryo
IPC分类号： C12N9/90 , C12P19/02 , C12P19/24
CPC分类号： C12N9/90 , C12P19/02 , C12P19/24

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