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1. 发明公开

EP2293711A4 PHYSICAL MODEL EYE SYSTEMS AND METHODS 审中-公开
标题翻译：物理模型眼的系统和方法
公开(公告)号：EP2293711A4
公开(公告)日：2014-01-15
申请号：EP09765271
申请日：2009-06-17
申请人： HOLDEN BRIEN VISION INST
发明人： EHRMANN KLAUS , BAKARAJU RAVI CHANDRA , FALK DARRIN
IPC分类号： A61B3/00 , A61B3/10 , G09B23/22 , G09B23/28 , G09B23/30 , G09B23/32
CPC分类号： G09B23/22 , A61B3/0025 , G09B23/34
摘要： An optically realistic model eye is described. The optically realistic eye model has an optical axis and includes: an anterior replaceable module comprising a model cornea, model iris and model lens rotatably mounted for rotation about said axis, said module being representative of an emmetropic or pathological natural eye; an enclosure located posterior to said module and adapted to enclose a retinal area within which an image of an external object is brought to focus by said module; and a photoactive device movable within said enclosure and retinal area and adapted to detect or reflect a portion of the image for inspection, processing or analysis.

2. 发明公开

EP2588096A4 COMPOSITION FOR PREVENTION AND TREATMENT OF CONTACT LENS PAPILLARY CONJUNCTIVITIS AND ALLERGIC EYE DISEASE 审中-公开
标题翻译：防止和治疗接触镜相关的表皮阴部锡组织点火和过敏性眼病的组合物
公开(公告)号：EP2588096A4
公开(公告)日：2013-12-25
申请号：EP11799986
申请日：2011-07-01
申请人： HOLDEN BRIEN VISION INST
发明人： HOLDEN BRIEN ANTHONY
IPC分类号： A61K31/164 , A61K9/00 , A61K9/08 , A61L12/00 , A61P27/14
CPC分类号： A61K31/164 , A61K9/0048 , A61K9/08
摘要： The invention provides a use of panthenol or dexpanthenol in the prevention and/or treatment of contact lens papillary conjunctivitis in a subject. A contact lens care solution containing 0.001 to 10% by dry weight dexpanthenol is also provided.
摘要翻译：本发明提供了泛醇或右泛醇在预防和/或治疗受试者的隐形眼镜乳头性结膜炎中的用途。还提供了包含0.001至10％干重的右旋潘生酚的隐形眼镜护理溶液。

3. 发明公开

EP2833848A4 LENSES, DEVICES, METHODS AND SYSTEMS FOR REFRACTIVE ERROR 有权
标题翻译：林森，VORRICHTUNGEN，VERFAHREN UND SYSTEMEFÜRBRECHUNGSFEHLER
公开(公告)号：EP2833848A4
公开(公告)日：2015-12-02
申请号：EP13771926
申请日：2013-04-05
申请人： HOLDEN BRIEN VISION INST
发明人： BAKARAJU RAVI CHANDRA , EHRMANN KLAUS , HO ARTHUR , HOLDEN BRIEN ANTHONY
IPC分类号： A61F9/00 , A61B3/00 , A61F2/14 , A61F2/16 , G02C7/02 , G02C7/04 , G02C7/06 , G02C7/08
CPC分类号： G02C7/022 , A61B3/0025 , A61B3/1015 , A61F2/14 , A61F2/145 , A61F2/1451 , A61F2/1613 , A61F2/1618 , A61F2/1637 , A61F2002/1681 , G02C7/02 , G02C7/027 , G02C7/04 , G02C7/041 , G02C7/06 , G02C7/061 , G02C7/083 , G02C2202/22 , G02C2202/24
摘要： Certain embodiments are directed to lenses, devices and/or methods. For example, a lens for an eye having an optical axis and an aberration profile along its optical axis, the aberration profile having a focal distance and including higher order aberrations having at least one of a primary spherical aberration component C(4,0) and a secondary spherical aberration component C(6,0). The aberration profile may provide, for a model eye with no aberrations and an on-axis length equal to the focal distance: (i) a peak, first retinal image quality (RIQ) within a through focus range that remains at or above a second RIQ over the through focus range that includes said focal distance, where the first RIQ is at least 0.35, the second RIQ is at least 0.1 and the through focus range is at least 1.8 Diopters; (ii) a RIQ of 0.3 with a through focus slope that improves in a direction of eye growth; and (iii) a RIQ of 0.3 with a through focus slope that degrades in a direction of eye growth. The RIQ may be Visual Strehl Ratio or similar measured along the optical axis for at least one pupil diameter in the range 3 mm to 6 mm, over a spatial frequency range of 0 to 30 cycles/degree inclusive and at a wavelength selected from within the range 540 nm to 590 nm inclusive.
摘要翻译：某些实施例涉及透镜，装置和/或方法。例如，具有光轴的透镜和沿其光轴的像差轮廓，像差轮廓具有焦距并且包括具有初级球面像差分量C（4.0）和二次球面像差分量C（6,0）。对于没有像差的模型眼睛和等于焦距的轴上长度，像差轮廓可以提供：（i）保持在等于或高于秒的通过对焦范围内的峰值，第一视网膜图像质量（RIQ）包括所述焦距的通过对焦范围的RIQ，其中第一RIQ至少为0.35，第二RIQ为至少0.1，并且通过对焦范围为至少1.8屈光度; （ii）具有改善眼睛生长方向的通过焦点斜率的0.3的RIQ; 和（iii）具有通过聚焦斜率的0.3的RIQ，其在眼睛生长的方向上降解。 RIQ可以是在0至30个循环/度范围内的空间频率范围内并且在从内部选择的波长处沿着光轴测量至少一个瞳孔直径在3mm至6mm范围内的视觉Strehl比率或类似物范围540纳米到590纳米。

4. 发明公开

EP2155041A4 DETERMINATION OF OPTICAL ADJUSTMENTS FOR RETARDING MYOPIA PROGRESSION 审中-公开
标题翻译：光学调节的测定延缓近视的发展
公开(公告)号：EP2155041A4
公开(公告)日：2012-01-25
申请号：EP08733399
申请日：2008-04-28
申请人： HOLDEN BRIEN VISION INST
发明人： EHRMANN KLAUS , HO ARTHUR
IPC分类号： A61B3/103 , A61F2/14 , G02C7/04
CPC分类号： A61B3/103 , A61B3/0025 , A61F9/00802 , A61F9/00804 , A61F9/00806 , A61F2009/00872 , G02C7/02 , G02C7/04 , G02C7/042 , G02C7/061 , G02C2202/24
摘要： A method or process for providing an anti-myopia lens or treatment for a patient's eye with progressive myopia, which involves (in one form) generating biometric data relating to the central and peripheral refractive errors of the eye, optionally together with data relating to the patient's visual or lifestyle needs and the patient's predisposition to progressive myopia. This data is input to a processor or algorithm that generates a basic lens design, a customised design or a program for reshaping the cornea of the eye. The selected modality is applied to the patient and its suitability is assessed with the result of the assessment feedback to the algorithm to generate a refined output design, which is applied to the patient. The process is repeated at intervals to check continued myopia progression and adjust the design of the selected modality after further measurement.

5. 发明公开

EP2139381A4 CHARACTERISING EYE-RELATED OPTICAL SYSTEMS 审中-公开
标题翻译：表征光学系统与眼睛连接
公开(公告)号：EP2139381A4
公开(公告)日：2015-01-07
申请号：EP08714475
申请日：2008-03-28
申请人： HOLDEN BRIEN VISION INST
发明人： EHRMANN KLAUS , HO ARTHUR , HOLDEN BRIEN ANTHONY
IPC分类号： A61B3/103 , A61B3/00 , A61B3/10
CPC分类号： A61B3/103 , A61B3/0008 , A61B3/1005 , A61B3/1015

6. 发明公开

EP2588128A4 LACTOFERRIN SEQUENCES, COMPOSITIONS AND METHODS OF CORNEAL WOUND TREATMENT 审中-公开
标题翻译：乳铁蛋白序列，组合物以及治疗眼角膜损伤方法
公开(公告)号：EP2588128A4
公开(公告)日：2014-03-19
申请号：EP11799985
申请日：2011-07-01
申请人： HOLDEN BRIEN VISION INST
发明人： ASHBY BENJAMIN DAVID , GARRETT QIAN , WILLCOX MARK
IPC分类号： A61K38/40 , A61K9/00 , A61P27/02
CPC分类号： A61K38/482 , A61K9/0048 , A61K38/40

7. 发明公开

EP2539763A4 CONTACT LENSES FOR MYOPIC EYES AND METHODS OF TREATING MYOPIA 有权
标题翻译： KONTAKTLINSEFÜRKURZSICHTIGE AUGEN UND VERFAHREN ZUR BEHANDLUNG VON KURZSICHTIGKEIT
公开(公告)号：EP2539763A4
公开(公告)日：2013-11-13
申请号：EP11750085
申请日：2011-03-03
申请人： HOLDEN BRIEN VISION INST
发明人： HOLDEN BRIEN ANTHONY , SCHMID GREGOR , SANKARIDURG PADMAJA RAJAGOPAL , HO ARTHUR , LAZON PERCY FABIAN , MARTINEZ ALDO ABRAHAM , SMITH EARL LEO III
IPC分类号： G02C7/04 , G02C7/06
CPC分类号： G02C7/044 , G02C7/041 , G02C7/045 , G02C7/047 , G02C7/063 , G02C2202/06 , G02C2202/24
摘要： A contact lens and a method for treating an eye with myopia is described. The contact lens includes an inner optic zone and an outer optic zone. The outer optic zone includes at least a portion with a first power, selected to correct distance vision. The inner optic zone has a relatively more positive power (an add power). In some embodiments the add power is substantially constant across the inner optic zone. In other embodiments the add power is variable across the inner optic zone. While in some embodiments the inner optic zone has a power designed to substantially eliminate lag of accommodation in the eye with myopia, in other embodiments, the add power may be higher.
摘要翻译：描述了隐形眼镜和用于治疗眼睛近视的方法。隐形眼镜包括内部光学区域和外部光学区域。外部光学区域至少包括具有第一功率的部分，被选择用于校正距离视力。内部光学区具有相对较大的正功率（增加功率）。在一些实施例中，所述附加功率在所述内部光学区域上基本恒定。在其他实施例中，增加功率在内部光学区域是可变的。虽然在一些实施例中，内部光学区具有被设计为基本上消除眼睛中具有近视眼的适应的滞后的功率，但在其他实施例中，增加的功率可能更高。

8. 发明公开

EP2537062A4 CORNEAL REMODELLING CONTACT LENSES AND METHODS OF TREATING REFRACTIVE ERROR USING CORNEAL REMODELLING 有权
标题翻译：与HORNHAUTNEUMODELLIERUNG和方法隐形眼镜使用HORNHAUTNEUMODELLIERUNG屈光不正的治疗
公开(公告)号：EP2537062A4
公开(公告)日：2013-11-13
申请号：EP11750084
申请日：2011-03-03
申请人： HOLDEN BRIEN VISION INST
发明人： HO ARTHUR , SANKARIDURG PADMAJA RAJAGOPAL , HOLDEN BRIEN ANTHONY , LAZON PERCY FABIAN , CHEN XIANG , CONRAD FABIAN , SMITH EARL LEO III
IPC分类号： G02C7/04 , A61F9/00
CPC分类号： G02C7/047 , G02C7/04 , G02C7/044 , G02C2202/24
摘要： Contact lenses are described with a corneal remodelling effect. This corneal remodelling effect is one or both of broad-area corneal remodelling and localised remodelling. The contact lenses may also have a refractive power. The refractive power may vary across the lens and for myopia may have increased power centrally. The increased power may be provided over a lens area that has increased thickness due to localised remodelling.

9. 发明公开

EP2929393A4 OPHTHALMIC OPTICAL LENS FOR VISION CORRECTION HAVING ONE OR MORE AREAS OF MORE POSITIVE POWER 有权
标题翻译：矫正视力的眼睛光学镜头，具有一个或多个领域具有较强的积极表现
公开(公告)号：EP2929393A4
公开(公告)日：2016-08-17
申请号：EP13863317
申请日：2013-12-10
申请人： HOLDEN BRIEN VISION INST
发明人： HOLDEN BRIEN ANTHONY , SANKARIDURG PADMAJA RAJAGOPAL , EHRMANN KLAUS , CONRAD FABIAN , HO ARTHUR
IPC分类号： G02C7/06 , A61F2/14 , A61F2/16 , G02C7/04
CPC分类号： G02C7/044 , A61F2/1451 , A61F2/16 , G02C7/041 , G02C7/066 , G02C2202/24

10. 发明公开

EP2825910A4 LENS FOR MYOPIC EYE 有权
标题翻译：眼睛为短视的眼睛
公开(公告)号：EP2825910A4
公开(公告)日：2015-10-21
申请号：EP13761341
申请日：2013-03-14
申请人： HOLDEN BRIEN VISION INST
发明人： SANKARIDURG PADMAJA RAJAGOPAL , FEDTKE CATHLEEN , DONOVAN LESLIE ALAN , SMITH EARL LEO III , HO ARTHUR , HOLDEN BRIEN ANTHONY
IPC分类号： G02C7/06 , G02C7/02 , G02C7/04
CPC分类号： G02C7/066 , G02C7/027 , G02C7/043 , G02C7/045 , G02C7/06 , G02C2202/24

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