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1. 发明公开

EP0952786A1 MEASUREMENT OF VOLUMETRIC FLUID FLOW AND ITS VELOCITY PROFILE 失效
标题翻译：测量液体体积流动和流动速度
公开(公告)号：EP0952786A1
公开(公告)日：1999-11-03
申请号：EP97940463.0
申请日：1997-09-02
申请人： EndoSonics Corporation
发明人： CESPEDES, Edoardo Ignacio , LANCE , Charles, Theodoor , VAN DER STEEN, Antonius, Franciscus, Wilhelmus , LI, Wenguang , BOM, Nicolaas
IPC分类号： G01P5 , A61B8 , G01F1 , G01S15
CPC分类号： A61B8/06 , A61B8/12
摘要： A method to measure spatial fluid flow components and their velocity profiles in a number of locations in a cross-sectional area of a lumen or other body cavity by using ultrasound in which the cross-sectional area is interrogated by a plurality of ultrasonic beams; the estimation of the spatial flow components is obtained from a combination of estimations of axial, lateral and total flow; the estimation of one or more flow components is obtained through any combination of time-shift and decorrelation analysis of two or more beam-signals of the interrogating ultrasound transducer; and the estimation accuracy is further improved by the use of a reference decorrelation curve obtained from experiments or beam-theory or both.

2. 发明公开

EP0920883A1 Modular imaging/treatment catheter assembly and method 有权
标题翻译：模块化导管用于映射和治疗和装配过程
公开(公告)号：EP0920883A1
公开(公告)日：1999-06-09
申请号：EP98309885.6
申请日：1998-12-02
申请人： EndoSonics Corporation
发明人： Baker, Bruce A. , Varney, Clifford R. , Eberle, Michael J.
IPC分类号： A61M29/02 , A61M25/10
CPC分类号： A61M25/10 , A61B8/00 , A61B8/0891 , A61B8/12 , A61B8/4416 , A61B8/445 , A61B2090/3784 , A61B2090/3966 , Y10T29/42
摘要： Catheter assembly and method in which an imaging transducer is positioned proximally of a treatment device at the distal end of a catheter. Unrestricted flow between a fluid lumen in the catheter and the treatment device is provided by an annular passageway formed between the walls of a marker tube which extends through the transducer and a guide wire tube which passes through the marker tube, and by a plenum chamber which is formed between the distal end of the catheter and the proximal end of the marker tube in communication with the fluid lumen and the flow passageway. The catheter, the treatment device, and the transducer are all constructed as individual modular units which can be assembled together as desired to form the assembly.

3. 发明公开

EP0611291A1 METHOD AND APPARATUS FOR REMOVING ARTIFACTS FROM AN ULTRASONICALLY GENERATED IMAGE OF A SMALL CAVITY 失效
标题翻译： DEVICE神器从超声图像的小腔的拆卸
公开(公告)号：EP0611291A1
公开(公告)日：1994-08-24
申请号：EP92914893.0
申请日：1992-06-19
申请人： ENDOSONICS CORPORATION
发明人： EBERLE, Michael, J.
IPC分类号： A61B8 , G01S7
CPC分类号： A61B8/12 , A61B8/445 , G01S7/52026
摘要： L'invention se rapporte à un appareil et à un procédé qui permettent de représenter en images des petites cavités du corps humain et dans lesquels des formes d'ondes de référence, destinées à être utilisées pour produire une image améliorée, sont générées in vivo plutôt qu'in vitro comme c'est le cas dans les techniques classiques. Ces formes d'ondes de référence sont utilisées pour débarrasser les signaux d'imagerie des bruits parasites qui sont à l'origine des artefacts apparaissant dans les images générées à partir de ces signaux. La sonde d'imagerie de l'appareil est à cet effet d'abord introduite dans une première zone du système vasculaire devant être représenté en image et les formes d'ondes de référence sont recueillies. Une fois terminée cette opération de collecte des formes d'ondes de référence, la sonde d'imagerie est introduite plus avant dans le système vasculaire jusqu'à une seconde zone devant être représentée en images. Si de nouvelles formes d'ondes de référence sont requises, la sonde d'imagerie est simplement retirée de la première zone du système vasculaire ou de nouvelles formes d'onde de référence sont recueillies, puis la sonde d'imagerie est à nouveau introduite plus avant dans la seconde zone, qui doit être représentée en images. La présente invention décrit également un appareil d'imagerie capable de prendre des images de la région proche de la surface de la sonde et qui, à cet égard, élimine les artefacts dans les formes d'ondes d'imagerie qui habituellement forment une couronne dans l'image visualisée de la région se trouvant au périmètre de la sonde.

4. 发明公开

EP1477827A1 A method and apparatus for creating a color blood flow image based upon ultrasonic echo signals received by an intravascular ultrasound imaging probe 失效
标题翻译：用于通过超声波的装置在血管内超声回波描记术的血流的彩色图像显示方法和装置，接收的回波信号
公开(公告)号：EP1477827A1
公开(公告)日：2004-11-17
申请号：EP04076810.3
申请日：1998-04-02
申请人： EndoSonics Corporation
发明人： O'Donnell, Matthew , Eberle, Michael J , Stephens, Douglas N , Litzza, Gerald, , Ziegenbein, Randy , Bleam, David , Wu, Ching-Chen
IPC分类号： G01S15/89 , A61B8/06 , A61B8/08
CPC分类号： G01S15/8979 , A61B8/06 , A61B8/13 , G01S7/52026 , G01S7/52071
摘要： A blood flow detection and imaging method and system is described for displaying images in accordance with signals transmitted from an intravascular ultrasound transducer probe. The image processor includes means for independently designating persistence factors for smoothing calculated speed and power of the dynamic portion of a field of view within a vasculature. Furthermore, the designation of a particular image point within a field of view as a dynamic image point (such as a blood flow region) as opposed to a static image point (such as a tissue region) is determined by averaging signal values for image points proximate to an image point of interest over both time and space.
摘要翻译：中的血流检测和成像的方法和系统描述了用于从血管内超声换能器探头显示在雅舞蹈用信号反mitted图像。图像处理器包括：用于指定unabhängig持久性因子的脉管系统中的平滑计算出的速度和视场的动态部分的功率。进一步，特定imagepoint的视野内的指定为动态图像点（颜色：诸如血流区域），而不是静态图像点（搜索作为组织区域）是确定性的通过用于图像点平均信号值开采接近过时间和空间感兴趣的图像点。

5. 发明授权

EP0707453B1 ULTRASONIC APPARATUS FOR INTRAVASCULAR IMAGING 失效
标题翻译： DEVICE血管心脏的演示使用超声
公开(公告)号：EP0707453B1
公开(公告)日：2004-06-23
申请号：EP95917583.7
申请日：1995-04-19
申请人： ENDOSONICS CORPORATION
发明人： O'DONNELL, Matthew , EBERLE, Michael J. , STEPHENS, Douglas N. , LITZZA, Gerald L. , HAVILAND, Daniel S.
IPC分类号： A61B8/12 , A61B8/06
CPC分类号： A61B8/06 , A61B8/12 , A61B8/445 , A61B8/4483 , A61B8/4488 , A61B8/4494 , B06B1/0633 , B06B1/067 , B06B1/0674 , B06B2201/76 , G01S15/892 , G01S15/8979 , G01S15/8981 , G01S15/899 , G10K11/004 , G10K11/008 , Y10T29/42

6. 发明公开

EP0853919A3 A high resolution intravascular ultrasound transducer assembly having a flexible substrate and method for manufacture thereof 失效
标题翻译：高分辨率血管内超声换能器，其包括用于其制备的柔性基板和方法
公开(公告)号：EP0853919A3
公开(公告)日：2001-05-09
申请号：EP98200020.0
申请日：1998-01-07
申请人： ENDOSONICS CORPORATION
发明人： Eberle, Michael J. , Finsterwald, Michael P.
IPC分类号： B06B1/06
CPC分类号： A61B1/0011 , A61B8/12 , A61B8/445 , A61B8/4488 , B06B1/0622 , B06B1/0633 , H05K1/189 , Y10T29/42 , Y10T29/49005 , Y10T29/4913
摘要： An ultrasound transducer assembly of the present invention includes a flexible circuit to which an ultrasound transducer array and integrated circuitry are attached during fabrication of the ultrasound transducer assembly. Integrated circuitry and transducer elements are attached to the flexible circuit while the flexible circuit is in a substantially flat shape. The contacts of the transducer elements are positioned on substantially the same plane such that electrical contact with signal and ground lines on the flexible circuit is established without the need for conductive bridges to physically remote electrodes. In an embodiment of the invention wherein the transducer elements are arranged in a cylindrical array, gaps are entirely filled with backing material having a relatively low acoustic impedance. Structure integrity is enhanced and a path to ground facilitated by electrically conductive disks attached to the ends of the transducer assembly.

7. 发明公开

EP0707453A1 ULTRASONIC APPARATUS AND METHOD FOR INTRAVASCULAR IMAGING 失效
标题翻译： DEVICE血管心脏的演示使用超声
公开(公告)号：EP0707453A1
公开(公告)日：1996-04-24
申请号：EP95917583.0
申请日：1995-04-19
申请人： ENDOSONICS CORPORATION
发明人： O'DONNELL, Matthew , EBERLE, Michael J. , STEPHENS, Douglas N. , LITZZA, Gerald L. , HAVILAND, Daniel S.
IPC分类号： A61B8 , B06B1 , G01S15 , G10K11
CPC分类号： A61B8/06 , A61B8/12 , A61B8/445 , A61B8/4483 , A61B8/4488 , A61B8/4494 , B06B1/0633 , B06B1/067 , B06B1/0674 , B06B2201/76 , G01S15/892 , G01S15/8979 , G01S15/8981 , G01S15/899 , G10K11/004 , G10K11/008 , Y10T29/42
摘要： An apparatus and method are described for imaging blood flow from within a vasculature. An ultrasound catheter probe (20) carrying an ultrasound transducer array (24) is inserted within a blood vessel (14). The transducer array emits ultrasound excitation signals and receives ultrasound echo waveforms reflected from blood and tissue in a region of the vasculature. A series of the echo waveforms resulting from a series of excitation signals are combined in a manner such that the echo signals from static features in the region, such as tissue and plaque (12), are significantly attenuated. The combined signal primarily represents the relatively dynamic features in the region (i.e., the blood flow). A blood flow image is constructed from the combined signal. The blood flow image is colored and combined with an image of the relatively static features in the region. Thereafter the combined image is displayed on a video display (28).

8. 发明公开

EP0519060A4 DILATING AND IMAGING APPARATUS 有权
标题翻译：脱水和成像装置
公开(公告)号：EP0519060A4
公开(公告)日：1993-02-24
申请号：EP92904268
申请日：1991-12-31
申请人： ENDOSONICS CORPORATION
发明人： EBERLE, MICHAEL, J. , HODGSON, JOHN, M.
IPC分类号： A61B8/12 , A61M29/02
CPC分类号： A61M25/104 , A61B8/12 , A61B8/445 , A61M2025/1079
摘要： A dilating and imaging apparatus (10) for attaching to and receiving pressurized fluid from a distal end of a catheter. The apparatus includes an inflatable balloon (18) and an imaging device (44) positioned behind an expandable portion of the balloon and upstream of the flow of pressurized fluid into the balloon so as to enable the balloon to deflate and achieve a smaller diameter than that of the imaging device (44), thus enabling the apparatus to enter a stenosis having a smaller diameter than the imaging device. In one embodiment of the invention, the imaging device can be maneuvered within the balloon while the balloon is inflated and dilating the stenosis.

9. 发明公开

EP1327417A3 Ultrasound catheter 失效
标题翻译： Ultraschallkatheter
公开(公告)号：EP1327417A3
公开(公告)日：2003-09-10
申请号：EP03075230.7
申请日：1994-01-14
申请人： EndoSonics Corporation
发明人： Eberle, Michael J. , Rizzuti, Gary P. , Kiepen, Horst F.
IPC分类号： A61B8/12 , B06B1/06
CPC分类号： A61B8/12 , A61B8/06 , A61B8/445 , A61B8/4483 , A61B8/4488 , A61B8/4494 , B06B1/0633 , B06B1/067 , B06B1/0674 , B06B2201/76 , G01S15/8915 , G01S15/892 , G01S15/8979 , G01S15/8981 , G01S15/899 , G10K11/004 , G10K11/008 , Y10T29/42
摘要： An ultrasound catheter is disclosed for providing substantially real-time images of small cavities. The ultrasound catheter is characterized by separate and distinct materials for backing the transducers and for carrying the electronics components. The separate materials comprise an electronics carrier meeting the requirements for holding the integrated circuitry of the ultrasound device and a backing material displaying superior characteristics relating to reducing ringing and minimizing the effect of other sources of signal degradation in the transducer assembly. Also, in accordance with the present invention, a technique is described for connecting the conductor lines of the separate transducer assembly and electronics body.
摘要翻译：公开了一种用于提供基本上实时的小空腔图像的超声波导管。超声导管的特征在于分离和不同的材料，用于支撑换能器和携带电子部件。单独的材料包括满足用于保持超声波装置的集成电路的要求的电子载体以及显示与减少振铃有关的优异特性并使传感器组件中的其它信号劣化的影响最小化的背衬材料。此外，根据本发明，描述了用于连接单独的换能器组件和电子体的导体线的技术。

10. 发明授权

EP0637937B1 ULTRASOUND CATHETER PROBE 失效
标题翻译：超声波传感器
公开(公告)号：EP0637937B1
公开(公告)日：2003-04-09
申请号：EP94906070.1
申请日：1994-01-14
申请人： ENDOSONICS CORPORATION
发明人： EBERLE, Michael, J. , RIZZUTI, Gary, P. , KIEPEN, Horst, F.
IPC分类号： A61B8/12 , A61B8/06
CPC分类号： A61B8/12 , A61B8/06 , A61B8/445 , A61B8/4483 , A61B8/4488 , A61B8/4494 , B06B1/0633 , B06B1/067 , B06B1/0674 , B06B2201/76 , G01S15/8915 , G01S15/892 , G01S15/8979 , G01S15/8981 , G01S15/899 , G10K11/004 , G10K11/008 , Y10T29/42
摘要： An ultrasound catheter (10) is disclosed for providing substantially real-time images of small cavities. The ultrasound catheter (10) is characterized by separate and distinct materials for backing the transducers (22) and for carrying the electronics components (18). The separate materials comprise an electronics carrier (20) meeting the requirements for holding the integrated circuitry (18) of the ultrasound device and a backing material (24) displaying superior characteristics relating to reducing ringing and minimizing the effect of other sources of signal degradation in the transducer assembly. Also, in accordance with the present invention, a technique is described for connecting the conductor lines of the separate transducer assembly and electronics body.

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