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1. 发明公开

EP0629295A1 VETERINARY DRUG RESIDUE SURVEILLANCE IN FRESH MEAT 失效
标题翻译： TIERÄRZTLICHEÜBERWACHUNGVONARZNEIMITTELRÜCKSTÄNDEN在FRISCHFLEISCH。
公开(公告)号：EP0629295A1
公开(公告)日：1994-12-21
申请号：EP93904291.0
申请日：1993-03-01
申请人： ENFER TECHNOLOGY LIMITED
发明人： O'CONNOR, Michael
IPC分类号： G01N33 , G01N35
CPC分类号： G01N33/94 , G01N33/12 , G01N33/74 , G01N35/0099 , Y10S435/962 , Y10S435/968 , Y10S436/825 , Y10S436/901 , Y10T436/25375
摘要： Analyse rapide permettant de déterminer la présence de restes de médicaments dans la viande fraîche ou le bétail. L'analyse permet d'obtenir les résultats en 90 minutes environ et de garantir ainsi l'absence de médicaments dans les carcasses avant qu'on ne les introduise dans la chaîne alimentaire. On a également prévu l'application de ce procédé d'analyse dans une analyse immunométrique employant des marqueurs chromogènes ou chimioluminescents.
摘要翻译： PCT No.PCT / IE93 / 00007 Sec。 371日期1994年9月1日 102（e）1994年9月1日PCT 1993年3月1日PCT公布。公开号WO93 / 18408 日期1993年9月16日一种用于快速检测家畜药物残留的方法，以进行质量认证，包括：从家畜中取出胆汁样品; 通过将样品真空通过具有能够结合待检测药物的固定化抗体的多孔二氧化硅免疫亲和柱洗涤胆汁样品，洗涤无杂质的柱，并用适当的溶剂洗脱任何与柱结合的药物; 并使用标记的抗体在竞争性免疫测定法中使清洁的胆汁样品反应。

2. 发明授权

EP1352248B1 TEST FOR TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES 有权
标题翻译：测试便携式海绵状脑病关于
公开(公告)号：EP1352248B1
公开(公告)日：2009-02-11
申请号：EP02716273.4
申请日：2002-01-18
申请人： ENFER TECHNOLOGY LIMITED
发明人： O'CONNOR, Michael
IPC分类号： G01N33/68
CPC分类号： G01N33/6896 , C12Q1/37 , G01N2333/4709 , G01N2800/2828
摘要： A method of detecting transmissible spongiform encephalopathies is described which involves (a) treating a sample of tissue, blood or a blood derivative from a test subject with alcohol and a detergent, (b) adding an agent which degrades normal prion protein (c) adding an agent which denatures abnormal prion protein, (d) adding a prion-specific antibody and (e) detecting binding of the antibody to the sample. Also described is a method of fixing abnormal prion protein to a substrate comprising (a) treating the protein or a sample suspected to contain the abnormal prion protein with alcohol and an anionic detergent and (b) adding a protease, in the presence of the substrate.

3. 发明公开

EP1352248A2 TEST FOR TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES 有权
标题翻译：测试便携式海绵状脑病关于
公开(公告)号：EP1352248A2
公开(公告)日：2003-10-15
申请号：EP02716273.4
申请日：2002-01-18
申请人： ENFER TECHNOLOGY LIMITED
发明人： O'CONNOR, Michael
IPC分类号： G01N33/68
CPC分类号： G01N33/6896 , C12Q1/37 , G01N2333/4709 , G01N2800/2828
摘要： A method of detecting transmissible spongiform encephalopathies is described which involves (a) treating a sample of tissue, blood or a blood derivative from a test subject with alcohol and a detergent, (b) adding an agent which degrades normal prion protein (c) adding an agent which denatures abnormal prion protein, (d) adding a prion-specific antibody and (e) detecting binding of the antibody to the sample. Also described is a method of fixing abnormal prion protein to a substrate comprising (a) treating the protein or a sample suspected to contain the abnormal prion protein with alcohol and an anionic detergent and (b) adding a protease, in the presence of the substrate.

4. 发明公开

EP2187959A2 DIAGNOSTIC METHOD AND KIT 有权
标题翻译：诊断步骤和试剂盒
公开(公告)号：EP2187959A2
公开(公告)日：2010-05-26
申请号：EP08788692.5
申请日：2008-08-18
申请人： Fusion Antibodies Limited , Enfer Technology Limited
发明人： OLWILL, Shane A. , JOHNSTON, James A. , KWOK, Hang Fai , WHELAN, Clare , CLARKE, John
IPC分类号： A61K39/04 , G01N33/569
CPC分类号： G01N33/5695 , A61K39/04
摘要： The invention relates to methods for diagnosis of tuberculosis in an animal, the methods comprising determiningthe presence or absence of, or an immune response toa group of antigens comprising(i) the group consisting of Rv3616 antigen,MPB70 antigen, MPB83 antigen, and ESAT 6 antigen; or (ii) at least seven of the antigens of the group consisting of Rv3616 antigen, MPB70 antigen, MPB83 antigen, ESAT 6 antigen, CFP10 antigen, α crystalline 2 antigen, PE35 antigen, and PPE68 antigen. Also providedis a method for the diagnosis of the presence of tuberculosis in a reservoir animal e.g. a badger, said method comprising determining the presence or absence of, or an immune responsetoRv3616 antigen, MPB70 antigen, andMPB83 antigen.Kits for carrying out the methods are also provided.

5. 发明授权

EP0909388B1 IMMUNOLOGICAL ASSAY FOR SPONGIFORM ENCEPHALOPATHIES 无效
标题翻译：免疫法海绵状脑病
公开(公告)号：EP0909388B1
公开(公告)日：2003-09-24
申请号：EP98903272.7
申请日：1998-02-06
申请人： ENFER TECHNOLOGY LIMITED
发明人： O'CONNOR, Michael
IPC分类号： G01N33/68 , G01N33/566
CPC分类号： C07K14/47 , C07K16/18
摘要： The invention relates to a method of detecting Transmissable Spongiform Encephalopathies (TSE) in animals, particularly in animal carcasses, using an anti-PrP antibody in an immunological assay. Also disclosed is a diagnostic kit for detecting TSE comprising the same antibody.

6. 发明授权

EP0629295B1 VETERINARY DRUG RESIDUE SURVEILLANCE IN FRESH MEAT 失效
标题翻译：黛比利奇ÜBERWACHUNG冯·阿尔茨海默
公开(公告)号：EP0629295B1
公开(公告)日：1997-06-25
申请号：EP93904291.7
申请日：1993-03-01
申请人： ENFER TECHNOLOGY LIMITED
发明人： O'CONNOR, Michael
IPC分类号： G01N33/94
CPC分类号： G01N33/94 , G01N33/12 , G01N33/74 , G01N35/0099 , Y10S435/962 , Y10S435/968 , Y10S436/825 , Y10S436/901 , Y10T436/25375
摘要： The invention relates to a rapid assay for the determination of drug residues in fresh meat or livestock. The assay allows the determination of results in approximately 90 minutes thus allowing certification of drug-free carcases before they enter the food chain. The assay in an immunometric assay using chromogenic or chemiluminescent labels.
摘要翻译： PCT No.PCT / IE93 / 00007 Sec。 371日期1994年9月1日 102（e）1994年9月1日PCT 1993年3月1日PCT公布。公开号WO93 / 18408 日期1993年9月16日一种用于快速检测家畜药物残留的方法，以进行质量认证，包括：从家畜中取出胆汁样品; 通过将样品真空通过具有能够结合待检测药物的固定化抗体的多孔二氧化硅免疫亲和柱洗涤胆汁样品，洗涤无杂质的柱，并用适当的溶剂洗脱任何与柱结合的药物; 并使用标记的抗体在竞争性免疫测定法中使清洁的胆汁样品反应。

7. 发明授权

EP2187959B1 DIAGNOSTIC METHOD AND KIT 有权
标题翻译：诊断步骤和试剂盒
公开(公告)号：EP2187959B1
公开(公告)日：2013-04-10
申请号：EP08788692.5
申请日：2008-08-18
申请人： Fusion Antibodies Limited , Enfer Technology Limited
发明人： OLWILL, Shane A. , JOHNSTON, James A. , KWOK, Hang Fai , WHELAN, Clare , CLARKE, John
IPC分类号： A61K39/04 , G01N33/569
CPC分类号： G01N33/5695 , A61K39/04

8. 发明授权

EP1682867B1 SAMPLE HOMOGENISER 有权
标题翻译：样本均质器
公开(公告)号：EP1682867B1
公开(公告)日：2008-05-07
申请号：EP04799294.6
申请日：2004-11-08
申请人： ENFER TECHNOLOGY LIMITED
发明人： CLARKE, John , LE FEUVRE, Peter , INDER, David
IPC分类号： G01N1/28 , C12M3/08 , B02C19/08
CPC分类号： G01N1/286 , C12M45/02
摘要： An apparatus for comminuting or homogenising biological tissue, comprising a container (1) with an interior bottom (5) comprised of an abrasive surface (6) a cap (10), and a grinder (20) receivable in the interior (2) of the container (1). Wherein the grinder (20) comprises a grinding head (21) and a cylindrical shaft (22) having an interior channel (23) defined therein; and at least one port (24) in the cylindrical shaft (22) through which comminuted material may flow into the interior channel (23), of the cylindrical shaft (22). The interior channel (23) of the cylindrical shaft (22) may communicate with the exterior of the container (1) so that the comminuted or homogenised sample that has passed through the port(s) (24) of the cylindrical shaft (22) may be removed from apparatus. In one embodiment the comminuted or homogenised sample is removed by aspiration.
摘要翻译：一种用于粉碎或均化生物组织的装置，包括具有由研磨表面（6），帽（10）和研磨器（20）组成的内部底部（5）的容器（1），所述容器（1）容器（1）。其中研磨机（20）包括研磨头（21）和其中限定有内部通道（23）的圆柱形轴（22）;其中，和圆柱形轴（22）中的至少一个端口（24），粉碎材料可通过该端口流入圆柱形轴（22）的内部通道（23）中。圆柱形轴（22）的内部通道（23）可以与容器（1）的外部连通，使得已经通过圆柱形轴（22）的端口（24）的粉碎或均化样品可能会从设备中移除。在一个实施方案中，通过抽吸除去粉碎或均化的样品。

9. 发明授权

EP0544805B1 HORMONE DETECTION METHODS 失效
标题翻译： HORMONNACHWEISVERFAHREN
公开(公告)号：EP0544805B1
公开(公告)日：1998-12-30
申请号：EP91916383.2
申请日：1991-08-23
申请人： ENFER TECHNOLOGY LIMITED
发明人： O'CONNOR, Michael
IPC分类号： G01N33/74 , G01N33/577 , A61B10/00 , A61D19/02 , C07K16/26
CPC分类号： G01N33/76 , A61B10/0012 , A61D17/002 , C07K16/26 , G01N33/743 , Y10S436/806 , Y10S436/817
摘要： A method of predicting ovulation and a test kit is described which allows one to accurately predict the time of ovulation in an animal in advance thus permitting the highest rate of pregnancy to be achieved and at the same time minimising embryonic death. Also described is a test kit for detecting and quantifying a given reproductive hormone and a method of optimising fertility in animals.

10. 发明公开

EP1682867A1 SAMPLE HOMOGENISER 有权
标题翻译： PROBENHOMOGENISATOR
公开(公告)号：EP1682867A1
公开(公告)日：2006-07-26
申请号：EP04799294.6
申请日：2004-11-08
申请人： ENFER TECHNOLOGY LIMITED
发明人： CLARKE, John , LE FEUVRE, Peter , INDER, David
IPC分类号： G01N1/28 , C12M3/08 , B02C19/08
CPC分类号： G01N1/286 , C12M45/02
摘要： An apparatus for comminuting or homogenising biological tissue, comprising a container (1) with an interior bottom (5) comprised of an abrasive surface (6) a cap (10), and a grinder (20) receivable in the interior (2) of the container (1). Wherein the grinder (20) comprises a grinding head (21) and a cylindrical shaft (22) having an interior channel (23) defined therein; and at least one port (24) in the cylindrical shaft (22) through which comminuted material may flow into the interior channel (23), of the cylindrical shaft (22). The interior channel (23) of the cylindrical shaft (22) may communicate with the exterior of the container (1) so that the comminuted or homogenised sample that has passed through the port(s) (24) of the cylindrical shaft (22) may be removed from apparatus. In one embodiment the comminuted or homogenised sample is removed by aspiration.

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