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1. 发明公开

EP3725161A1 METHOD OF PRODUCING LACTIC ACID BACTERIA DUAL-COATED WITH PROTEIN AND POLYSACCHARIDE BY USING PROTEIN HYDROLYSATE 有权
公开(公告)号：EP3725161A1
公开(公告)日：2020-10-21
申请号：EP20169113.6
申请日：2020-04-09
申请人： Cell Biotech Co., Ltd.
发明人： CHUNG, Myung Jun
IPC分类号： A23C9/123 , A23C9/13 , A23C9/137
摘要： The present disclosure relates to a method of producing lactic acid bacteria dual-coated with protein and polysaccharide by using a protein hydrolysate, and lactic acid bacteria having a dual coating, produced by the method. The lactic acid bacteria having a dual coating of protein and polysaccharide, produced according to the present disclosure, have very excellent dry-freezing viability, acid resistance and bile resistance. Accordingly, the lactic acid bacteria having a dual coating of protein and polysaccharide according to the present disclosure will be very useful for the production of fermented milk, processed milk, fermented soy products, processed foods, functional beverages, functional foods, common foods, etc.

2. 发明公开

EP3453718A1 LACTIC ACID BACTERIA-DERIVED PROTEIN AND PREPARATION METHOD THEREFOR 有权转让
公开(公告)号：EP3453718A1
公开(公告)日：2019-03-13
申请号：EP17874171.6
申请日：2017-02-15
申请人： Cell Biotech Co., Ltd.
发明人： CHUNG, Myung Jun
IPC分类号： C07K14/335 , C12N15/74 , A23L33/18 , A61K35/744 , A61K38/16
摘要： The present invention relates to a protein derived from lactic acid bacteria and a method for producing the same. The lactic acid bacteria-derived protein of the present invention is a purified protein isolated from lactic acid bacteria ( Lactobacillus rhamnosus ) having an excellent therapeutic effect against colorectal cancer. It has been demonstrated to have a remarkable effect against colorectal diseases, and thus is expected to be widely used as a natural protein therapeutic agent against colorectal diseases in the medical field.

3. 发明公开

EP3318251A2 COMPOSITION FOR PREVENTING OR TREATING OBESITY OR LIPID-RELATED METABOLIC DISEASE 有权
标题翻译：预防或治疗肥胖或脂质相关代谢疾病的组合物
公开(公告)号：EP3318251A2
公开(公告)日：2018-05-09
申请号：EP17198838.9
申请日：2017-10-27
申请人： Cell Biotech Co., Ltd.
发明人： CHUNG, Myung Jun
IPC分类号： A61K31/047 , A61K31/14 , A61K31/197 , A61K31/4188 , A61K31/4415 , A61K31/455 , A61K31/51 , A61K31/519 , A61K31/525 , A61K31/714 , A61K35/74 , A61P1/16 , A61P3/06 , A61P3/00 , A61P3/08 , A61P3/02 , A61P19/10 , A61P19/08 , A61P9/12 , A61P3/10 , A61P3/04
CPC分类号： A61K35/747 , A61K31/14 , A61K31/197 , A61K31/4188 , A61K31/4415 , A61K31/455 , A61K31/51 , A61K31/519 , A61K31/525 , A61K31/675 , A61K31/714 , A61K35/74 , A61K35/744 , A61P1/16 , A61P3/00 , A61P3/02 , A61P3/04 , A61P3/06 , A61P3/08 , A61P3/10 , A61P9/00 , A61P9/10 , A61P9/12 , A61K2300/00
摘要： The present invention provides a pharmaceutical composition and a food composition for preventing or treating lipid-related metabolic disease, which contain, as active ingredients, probiotics and a vitamin B complex. When the composition comprising the probiotics and the vitamin B complex is used, it may further promote in vivo absorption of the vitamin B complex, and may induce a synergistic effect on a reduction in blood lipid levels, thereby exhibiting an effect on the alleviation, prevention or treatment of obesity and lipid-related metabolic disease.
摘要翻译：本发明提供用于预防或治疗脂质相关代谢疾病的药物组合物和食物组合物，其包含作为活性成分的益生菌和维生素B复合物。当使用包含益生菌和维生素B复合物的组合物时，其可以进一步促进维生素B复合物的体内吸收，并且可以引起对血脂水平降低的协同效应，由此表现出对缓解，预防或治疗肥胖症和与脂质相关的代谢疾病。

4. 发明授权

EP2751129B1 PROTEIN P14 WITH ANTI-CANCER AND ANTI-ALLERGY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME 有权
标题翻译：具有抗癌和抗过敏活性的蛋白P14以及包含该抗癌活性的药物组合物
公开(公告)号：EP2751129B1
公开(公告)日：2018-01-24
申请号：EP12851727.3
申请日：2012-08-29
申请人： Cell Biotech Co., Ltd.
发明人： SEO, Jae Gu , CHUNG, Myung Jun , LEE, Hyun Gi
IPC分类号： C07K14/335 , A61K38/16 , A61K35/74 , A61P37/08 , A61P35/00
CPC分类号： C07K14/335 , A61K38/164
摘要： Disclosed are protein p14 which exhibits anti-cancer and anti-allergy activity, and a pharmaceutical composition for the treatment, management, alleviation, improvement or prevention of cancer and/or allergic diseases, comprising the same. The composition guarantees excellent anticancer effects with minimal side effects. Protein p14 induces the synthesis of IFN-gamma and regulates the production of IL-4, thus exhibiting preventive or therapeutic effects on allergic diseases.

5. 发明授权

EP2647694B1 DEAD LACTOBACILLUS BIOMASS FOR ANTIMICROBIAL USE AND A PRODUCTION METHOD THEREFOR 有权
标题翻译：用于杀菌剂的死菌乳酸菌生物质及其生产方法
公开(公告)号：EP2647694B1
公开(公告)日：2017-12-27
申请号：EP11838184.7
申请日：2011-10-27
申请人： Cell Biotech Co., Ltd. , Chung, Myung-jun
发明人： CHUNG, Myung Jun
IPC分类号： A23K20/195
CPC分类号： C12N1/20 , A23K10/16 , A23K40/10 , A61K35/744 , A61K35/747
摘要： The present invention relates to an antibacterial material comprising a tyndallized dead lactic acid bacteria lyophilizate and a dried tyndallized fermented filtrate prepared by a process comprising the steps of tyndallizing a fermented broth of lactic acid bacteria and then separating the tyndallized fermented broth into a tyndallized fermented filtrate and a tyndallized dead lactic acid bacteria-containing solution; freeze-drying the tyndallized dead lactic acid bacteria-containing solution so as to form a tyndallized dead lactic acid bacteria lyophilizate; fluidized-bed-drying or freeze-drying the tyndallized fermented filtrate so as to from a dried tyndallized fermented filtrate; and mixing the tyndallized dead lactic acid bacteria lyophilizate and the dried tyndallized fermented filtrate, and a preparing method thereof. The antibacterial material comprising the tyndallized dead lactic acid bacteria lyophilizate, according to the present invention, may have a homogeneous appearance and an excellent antibacterial activity, and thus may be appropriately used to prepare various medicines, foods, feeds, and cosmetics which require antibacterial activity and intestinal regulation.

6. 发明公开

EP3135754A1 BIFIDOBACTERIUM LONGUM CBT BG7 STRAIN AND FUNCTIONAL FOOD COMPOSITION CONTAINING SAME FOR PROMOTING GROWTH 有权
标题翻译： BIFIDOBACTERIUM-LONGUM-CBT-BG7-STAMM UND FUNKTIONALE NAHRUNGSMITTELZUSAMMENSETZUNG DAMIT ZURWACHSTUMSFÖRDERUNG
公开(公告)号：EP3135754A1
公开(公告)日：2017-03-01
申请号：EP15890172.8
申请日：2015-07-13
申请人： Cell Biotech Co., Ltd.
发明人： CHUNG, Myung Jun
IPC分类号： C12N1/20
CPC分类号： C12R1/01 , A23L33/135 , A23V2002/00 , A23Y2300/55 , A61K35/745 , C12N1/20
摘要： The present invention a Bi fidobacterium longum CBT BG7 Bifidobacterium, which has an excellent growth promoting effect and was internationally deposited with the Korean Collection for Type Culture (KCTC) of the Korea Research Institute of Bioscience and Biotechnology under accession number KCTC 12200BP. The strain of the present invention has a beneficial effect of promoting growth by promoting the digestion of human milk oligosaccharides to enhance immunity together with physical strength.
摘要翻译：本发明是一种具有优异生长促进作用的双歧杆菌长双歧杆菌CBT BG7双歧杆菌，并以保藏号KCTC 12200BP国际保藏在韩国生物科学和生物技术研究所的韩国收藏品种培养物（KCTC）。本发明的菌株通过促进人乳寡糖的消化来增强免疫力和身体强度，具有促进生长的有益效果。

7. 发明授权

EP2235158B1 METHOD OF PREPARING TRIPLE-COATING LACTIC ACID BACTERIA AND NANO PARTICLE COATING METHOD, TRIPLE-COATING LACTIC ACID BACTERIA PREPARED THEREBY AND ARTICLE COMPRISING THE SAME 有权
标题翻译：用于生产三层涂布乳酸菌涂装工艺利用纳米粒子，使生产的三层涂布乳酸菌及奶类这篇文章含
公开(公告)号：EP2235158B1
公开(公告)日：2013-12-25
申请号：EP08778856.8
申请日：2008-07-18
申请人： Cell Biotech Co., Ltd.
发明人： CHUNG, Myung Jun , KIM, Dong Myung , KIM, Jin Eung , LEE, Gwa Soo
IPC分类号： C12N1/20 , A23L1/30 , A61K35/74
CPC分类号： C12N1/20 , A23L33/135 , A61K35/747
摘要： The present invention relates to a method for preparing triple-coated lactic acid bacteria, triple-coated lactic acid bacteria prepared thereby, and an article comprising the same. More particularly, the present invention relates to a method for preparing lactic acid bacteria triple-coated with protein, polysaccharide and nanoparticles, triple-coated lactic acid bacteria prepared thereby, and an article comprising the same. The triple-coated lactic acid bacteria prepared according to the present invention provides have better acid resistance, bile resistance and stability in accelerated test than conventional double-coated lactic acid bacteria. They are not killed by gastric acid or bile acid upon uptake, and maintain their inherent physiological activities, and, therefore, they can be effectively used in various products, including fermented milk, processed milk, fermented soybean products, fermented kimchi products, functional drinks, functional foods, conventional foods, cosmetics, and the like.

8. 发明公开

EP2647694A2 DEAD LACTOBACILLUS BIOMASS FOR ANTIMICROBIAL USE AND A PRODUCTION METHOD THEREFOR 有权
标题翻译：生物物质大豆植物乳杆菌ZUR VERWENDUNG ALS抗菌抗生素
公开(公告)号：EP2647694A2
公开(公告)日：2013-10-09
申请号：EP11838184.7
申请日：2011-10-27
申请人： Cell Biotech Co., Ltd. , Chung, Myung-jun
发明人： CHUNG, Myung Jun
IPC分类号： C12N1/20 , C12Q1/02 , A61K35/74 , A23K1/17
CPC分类号： C12N1/20 , A23K10/16 , A23K40/10 , A61K35/744 , A61K35/747
摘要： The present invention relates to an antibacterial material comprising a tyndallized dead lactic acid bacteria lyophilizate and a dried tyndallized fermented filtrate prepared by a process comprising the steps of tyndallizing a fermented broth of lactic acid bacteria and then separating the tyndallized fermented broth into a tyndallized fermented filtrate and a tyndallized dead lactic acid bacteria-containing solution; freeze-drying the tyndallized dead lactic acid bacteria-containing solution so as to form a tyndallized dead lactic acid bacteria lyophilizate; fluidized-bed-drying or freeze-drying the tyndallized fermented filtrate so as to from a dried tyndallized fermented filtrate; and mixing the tyndallized dead lactic acid bacteria lyophilizate and the dried tyndallized fermented filtrate, and a preparing method thereof.
The antibacterial material comprising the tyndallized dead lactic acid bacteria lyophilizate, according to the present invention, may have a homogeneous appearance and an excellent antibacterial activity, and thus may be appropriately used to prepare various medicines, foods, feeds, and cosmetics which require antibacterial activity and intestinal regulation.
摘要翻译：本发明涉及一种抗菌材料，其包含硫酸化的死乳酸菌冻干物质和通过包括以下步骤制备的干燥的脱盐发酵滤液，所述方法包括将发酵的乳酸菌发酵液脱水，然后将经脱硫的发酵肉汤分离成发酵的发酵滤液和含有乳酸的死乳酸菌溶液; 冷冻干燥含有乳酸的死亡乳酸菌溶液，形成一种定型的死乳酸菌冻干物质; 流化床干燥或冷冻干燥发酵过的发酵滤液，以从干燥的经发酵的发酵滤液中; 并混合定型的死乳酸菌冻干物和干燥的脱脂发酵滤液及其制备方法。包含根据本发明的定型的死乳酸菌冻干物质的抗菌材料可以具有均匀的外观和优异的抗菌活性，因此可以适当地用于制备需要抗菌活性的各种药物，食品，饲料和化妆品和肠道调节。

9. 发明公开

EP3318262A3 COMPOSITION FOR PREVENTING OR TREATING BONE DISEASE, OBESITY AND LIPID-RELATED METABOLIC DISEASE 无效
公开(公告)号：EP3318262A3
公开(公告)日：2018-08-15
申请号：EP17198356.2
申请日：2017-10-25
申请人： Cell Biotech Co., Ltd.
发明人： CHUNG, Myung Jun
IPC分类号： A61K35/00
CPC分类号： A61K35/744 , A61K9/0053 , A61K31/015 , A61K31/047 , A61K31/07 , A61K31/122 , A61K31/14 , A61K31/197 , A61K31/355 , A61K31/375 , A61K31/4188 , A61K31/4415 , A61K31/455 , A61K31/51 , A61K31/519 , A61K31/525 , A61K31/59 , A61K31/592 , A61K31/593 , A61K31/714 , A61K35/74 , A61K35/747 , A61K45/06 , A61K2035/11 , A61P1/16 , A61P3/00 , A61P3/02 , A61P3/04 , A61P3/06 , A61P3/08 , A61P3/10 , A61P9/12 , A61P19/08 , A61P19/10 , A61K2300/00
摘要： The present invention relates to a functional composition for preventing, alleviating or treating bone disease and lipid-related metabolic disease, and more particularly to a composition which comprises a combination of probiotics and a vitamin complex, which is capable of effectively preventing, alleviating or treating bone disease, obesity and lipid-related metabolic disease by synergistic effects on antioxidant activity, a reduction in blood lipid levels and the promotion of in vivo absorption of calcium and iron.

10. 发明公开

EP3318263A1 ANTIOXIDANT COMPOSITION AND COMPOSITION FOR IMPROVEMENT OF SKIN CONDITIONS 有权转让
标题翻译：用于改善皮肤状况的抗氧化剂组合物和组合物
公开(公告)号：EP3318263A1
公开(公告)日：2018-05-09
申请号：EP17198853.8
申请日：2017-10-27
申请人： Cell Biotech Co., Ltd.
发明人： CHUNG, Myung Jun
IPC分类号： A61K35/741 , A61K35/744 , A61K35/747 , A61K31/375 , A61P17/18 , A61P17/00
CPC分类号： A61K35/747 , A61K8/676 , A61K8/99 , A61K31/375 , A61K35/741 , A61K35/744 , A61P17/00 , A61P17/18 , A61P35/00 , A61P37/08 , A61Q19/08 , A61K2300/00
摘要： The present invention provides an antioxidant composition and/or a composition for improving skin conditions, which contain, as active ingredients, probiotics and vitamin C. The composition containing probiotics and vitamin C as active ingredients according to the present invention can exhibit a synergistic effect on the activation of antioxidant enzyme, thereby exhibiting an antioxidant effect and a skin condition improving effect. In addition, the composition containing probiotics and vitamin C as active ingredients according to the present invention can more effectively induce antioxidant effects to activate energy metabolism in vivo, thereby exhibiting a significant synergistic effect on weight loss.
摘要翻译：本发明提供用于改善皮肤状况的抗氧化剂组合物和/或组合物，其含有益生菌和维生素C作为活性成分。根据本发明的含有益生菌和维生素C作为活性成分的组合物可以对抗氧化酶的活化，从而表现出抗氧化效果和皮肤状况改善效果。另外，根据本发明的含有益生菌和维生素C作为活性成分的组合物可以更有效地诱导抗氧化作用以活化体内的能量代谢，由此对体重减轻显示出显着的协同效应。

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