专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP1948259A1 ACELLULAR BIOABSORBABLE TISSUE REGENERATION MATRICES PRODUCED BY INCUBATING ACELLULAR BLOOD PRODUCTS 失效转让
标题翻译： DURCH INKUBATION VONAZELLULÄRENBLUTPRODUKTEN HERGESTELLTEAZELLULÄREBIORESORBIERBARE GEWEBEREGENERATIONSMATRIZEN
公开(公告)号：EP1948259A1
公开(公告)日：2008-07-30
申请号：EP06817419.2
申请日：2006-10-26
申请人： Total Record, Inc. , Ahlfors, Jan-Eric W.
发明人： AHLFORS, Jan-Eric, W.
IPC分类号： A61L27/36
CPC分类号： A61L27/3616 , A61K9/0002 , A61K35/30 , A61K35/545 , A61K38/16 , A61K38/385 , A61K38/40 , A61K38/51 , A61K39/395 , A61K45/00 , A61L27/3604 , A61L27/3683 , A61L27/38 , A61L27/54 , A61L27/58 , A61L2300/412 , A61L2300/45 , A61L2430/32 , A61L2430/38 , A61L2430/40
摘要： The present invention provides methods and compositions useful in the regeneration of damaged, lost and/or degenerated tissue in humans and animals. In certain embodiments, the present invention provides an acellular bioabsorbable tissue regeneration matrix, methods of making such a matrix, and methods of using such a matrix for the regeneration of damaged, lost and/or degenerated tissue. In certain embodiments, methods and compositions of the present invention are useful in the treatment of damaged, lost and/or degenerated nerve tissue.
摘要翻译：本发明提供了可用于人类和动物中损伤的，损失的和/或退化的组织再生的方法和组合物。在某些实施方案中，本发明提供了一种无细胞生物可吸收组织再生基质，制备这种基质的方法，以及使用这种基质用于再生损伤的，损失的和/或退化的组织的方法。在某些实施方案中，本发明的方法和组合物可用于治疗损伤的，损失的和/或退化的神经组织。

2. 发明公开

EP1727893A2 AUTOGENIC LIVING SCAFFOLDS AND LIVING TISSUE MATRICES: METHODS AND USES THEREOF 失效
标题翻译： AUTOGENISCHE生活塔和活组织基质：过程，并使用
公开(公告)号：EP1727893A2
公开(公告)日：2006-12-06
申请号：EP05849047.5
申请日：2005-03-09
申请人： Ahlfors, Jan-Eric W.
发明人： Ahlfors, Jan-Eric W.
IPC分类号： C12N5/08
摘要： A 3-dimensional structure comprising suitable cells (or entities) and the ECM (or matrix) that has been completely produced and arranged by these cells (or entities) that promotes the differentiation, dedifferentiation and/or transdifferentiation of cells and/or formation of tissue in vitro and in vivo, while at the same time promoting cell growth, proliferation, migration, acquisition of in vivo-like morphology, or combinations thereof, and that 1. provides structural and/or nutritional support to cells, tissue, organs, or combinations thereof, termed an 'Autogenic Living Scaffold' (ALS); or 2. is capable of being transformed into a more complex tissue (or matrix) or a completely different type of tissue (or matrix), termed a 'Living Tissue Matrix' (LTM). Autogenic means it is self-produced. The living cells that produce the LTM or ALS, or are added to Autogenic Living Scaffolds, may be genetically engineered or otherwise modified. The matrix component of the ALS or LTM provides a structural framework for cells that guide their direction of growth, enables them to be correctly spaced, prevents overcrowding, enables cells to communicate between each other, transmit subtle biological signals, receive signals from their environment, form bonds and contacts that are required for proper functioning of all cells within a unit such as a tissue, or combinations thereof. The ALS or LTM may thus provide proper or supporting mechanical and chemical environments, signals, or stimuli to other cells, to the cells that produce the ALS, to surrounding tissue at an implantation site, to a wound, for in vitro and ex vivo generation and regeneration of cells, tissue and organs, or combinations thereof. They may also provide other cells with nutrients, growth factors, and/or other necessary or useful components. They may also take in or serve as buffers for certain substances in the environment, and have also some potential at adapting to new environments.

3. 发明授权

EP1727893B1 AUTOGENIC LIVING SCAFFOLDS AND LIVING TISSUE MATRICES: METHODS AND USES THEREOF 失效
标题翻译： AUTOGENISCHE生活塔和活组织基质：过程，并使用
公开(公告)号：EP1727893B1
公开(公告)日：2012-12-12
申请号：EP05849047.5
申请日：2005-03-09
申请人： Ahlfors, Jan-Eric W.
发明人： Ahlfors, Jan-Eric W.
IPC分类号： C12N5/077 , C12N5/0793

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式