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81. 发明授权

EP0259307B1 CONTROL OF LABORATORY EVAPORATION 失效
标题翻译：实验室蒸发控制
公开(公告)号：EP0259307B1
公开(公告)日：1991-08-28
申请号：EP86901641.0
申请日：1986-02-12
申请人： ZYMARK CORPORATION
发明人： FRISWELL, David, R.
IPC分类号： B01D1/14 , F26B3/00 , F26B5/00 , G01N1/18 , G01N1/22 , B01L11/00
CPC分类号： B01D1/14
摘要： Apparatus for evaporating liquid to obtain solid residue. The invention is particularly useful where small quantities of a solid are to be recovered from a first liquid medium (14) and dissolved in another liquid medium. The invention comprises a receptacle (12) for holding the liquid (14) to be treated and flow directing apparatus (24) to localize transport of an evaporating or carrier gas along the wall of the receptacle as it moves downwardly and into contact with the material to be treated. Such localization of inlet gas also provides a relatively quiescent central zone (32) in the receptacle through which the gas, carrying evaporated liquid, can be removed without disturbing the flow of inlet gas. Apparatus (76, 60) to sense the temperature of the evaporating process and terminate the process at any appropriate temperature conditions is provided.

82. 发明公开

EP0410681A3 Pump inserter for test tubes 失效
标题翻译：用于测试管的泵插件
公开(公告)号：EP0410681A3
公开(公告)日：1991-08-21
申请号：EP90308069.5
申请日：1990-07-24
申请人： HELENA LABORATORIES CORPORATION
发明人： Golias, Tipton Lee , Mayes, Ovay Hilton , Sarrine, Robert James
IPC分类号： B01L11/00 , G01N1/00 , G01N35/06
CPC分类号： G01N35/1079 , B01L3/0293 , Y10T436/114165
摘要： Apparatus for securing pump mechanisms (20) to test tubes (14) sealed by a closure (24) such that the contents of the test tubes (14) may be discharged without removing the closure. The apparatus includes a rack for holding a plurality of pump mechanisms (20), each of the pump mechanisms (20) including a downwardly extending needle (28) or the like for penetrating the closure (24) of the test tube (14). The test tubes (14) are arranged within a tray (16) in a plurality of rows, and each row is sequentially advanced into position. As each row is in position, the pump mechanism (20) is moved toward the row of test tubes (14) to penetrate the test tube closures (24). The pump mechanisms (20) thereafter released, the rack filled with a next series of pump mechanisms (20), the test tube (14) array indexed, and the cycle of steps is repeated. The pump mechanism needles (28) are initially imbedded in a protective packaging (34). The apparatus strips away the protective packaging to expose the sharpened points or tips (28) of the pump mechanism (20).

83. 发明公开

EP0424633A2 Automated method and device for performing solid-phase diagnostic assay 失效
标题翻译：用于进行固相诊断分析的自动化方法和装置。
公开(公告)号：EP0424633A2
公开(公告)日：1991-05-02
申请号：EP90116379.0
申请日：1990-08-27
申请人： ABBOTT LABORATORIES
发明人： Khalil, Omar S. , Huff, Denise G. , Hanna, Charles F. , Zurek, Thomas F.
IPC分类号： G01N33/543 , B01L3/00 , B01L11/00
CPC分类号： B01L3/50255 , B01L2300/069 , B01L2300/0829 , B01L2400/0406 , G01N33/54313 , G01N33/54366 , G01N33/5762 , G01N33/94 , G01N35/1002 , Y10S435/805 , Y10T436/255 , Y10T436/2575
摘要： A disposable device (10) suitable for performing automated solidphase diagnostic assays which employs microparticles to complex an analyte and where the microparticle complex becomes retained and immobilized on a fibrous matrix such that the presence of analyte on the microparticles can be detected by optical means. A device (10) is disclosed having a sample well (12) for receiving a sample and reagents for forming a reaction mixture, a read well (14) comprising (a) an entrance port and holding means for receiving and holding a quantity of sample and assay reagents, (b) a fibrous matrix (22) for retaining and immobilizing microparticle/analyte complexes for detection, said fibrous matrix (22) positioned below said holding means, and having an average spatial separation of fibers greater than the average diameter of said microparticles, (c) means (24) positioned below said fibrous matrix for assisting the flow of sample and assay reagents through said fibrous matrix, such as an absorbent material (24) or vacuum below said fibrous matrix, (d) means (26) for creating a substantially light-tight real surrounding the well, (e) means (28) for venting air entrapped in the absorbent material and which is displaced by fluids absorbed therein, and (f) passage means (16) communicating between the sample well and the read well whereby sample and reaction mixtures can be transferred and washed from said sample well into said read well without being contacted by any apparatus.
摘要翻译：适合于执行其采用微粒到复杂的分析物上，并且其中所述微粒复合物变得保留并固定在检测纤维基质做了微粒分析物的存在可以通过光学手段被检测到自动固相诊断测定的一次性装置。一种设备盘游离缺失具有样品孔用于接收样品和试剂形成反应混合物，读出以及包括入口端口的（a）和保持装置，用于接收和保持样品和检测试剂的量，（b）一种纤维矩阵用于保持和固定微粒/分析物复合物进行检测，所述位于下方，所述纤维基质保持装置，以及具有在纤维上比所述微粒的平均直径大的平均空间分离，（C）是指位于其下方，所述纤维基质用于辅助通过所述纤维性基质，色样和分析试剂的流：如在吸收材料或低于所述纤维基质真空，（D）用于产生基本不透光的实际围绕井，（e）用于排放在吸湿截留的空气这是通过在其中被吸收的流体移动，并且样品之间（F）的装置通道连通孔中，将读好，由此样品和反应混合物材料和所有功能能够被传输并从所述样品井到所述不受任何装置被接触以及读洗涤。

84. 发明公开

EP0384683A2 Apparatus for filling tubes 失效
标题翻译： Vorrichtung zumFüllenvonRöhrchen。
公开(公告)号：EP0384683A2
公开(公告)日：1990-08-29
申请号：EP90301758.0
申请日：1990-02-19
申请人： EOLAS THE IRISH SCIENCE & TECHNOLOGY AGENCY
发明人： Garvey, Cormac , Lang, John
IPC分类号： G01N35/06 , B01L11/00
CPC分类号： B01L3/0293 , B65B3/003 , G01N1/18
摘要： An apparatus (10) comprises a conveyor system 11 for conveying tubes (12), having respective self-sealing closure means, sequentially to a station whereupon the conveyor system (11) is temporarily halted. At the station, a clamping means (13) having a clamp (13a) lowers to prevent movement of the tube (12a). An arm (19) moves in the direction of the tube (12a) to enable a hollow needle (17) to penetrate the closure means (30) of the tube (12a). A metering means (15) enables a predetermined volume of a fluid, preferably liquid agar, to be introduced into the tube (12a). Following release of the needle (17) from the closure means (30), the conveyor systems moves to enable another tube (12b) to arrive at the station.
摘要翻译：一种装置（10）包括用于输送管（12）的输送系统11，其具有相应的自密封闭合装置，其顺序地传送到传送系统（11）暂时停止的站。在工位，具有夹具（13a）的夹紧装置（13）降低以防止管（12a）移动。臂（19）沿着管（12a）的方向移动，以使空心针（17）穿过管（12a）的封闭装置（30）。计量装置（15）使得能够将预定体积的流体（优选液体琼脂）引入管（12a）中。在从封闭装置（30）释放针（17）之后，输送系统移动以使得另一个管（12b）到达该工位。

85. 发明公开

EP0252585A3 Sample/reagent container for liquid analyses 失效
标题翻译：用于液体分析的样品/试剂容器
公开(公告)号：EP0252585A3
公开(公告)日：1989-04-19
申请号：EP87303941.6
申请日：1987-05-01
申请人： Bayer Corporation
发明人： Cassaday, Michael M.
IPC分类号： B01L11/00 , B01L3/00 , G01N35/08
CPC分类号： B01J19/16 , B01L99/00 , G01N35/1095 , G01N2035/00277
摘要： In the analysis of liquids an isolation liquid is used to separate successive liquid samples. The invention provides a container (10) for liquid sample or reagent (14) and for a layer of isolation liquid (30) atop the liquid sample or reagent, the isolation liquid layer being confined and maintained by the use of a porous retention device (26) suitably in the form of a ring (281. The device contacts both the isolation liquid layer and the liquid sample or reagent, and is preferably such as to cause the formation of a convex meniscus on the liquid sample, thus providing improved support for the isolation liquid layer.

86. 发明公开

EP0304765A2 Device for pouring washing water onto multi-well plates 失效
标题翻译： Verfahren zum Einbringen von Wasser在Titrationsplatten。
公开(公告)号：EP0304765A2
公开(公告)日：1989-03-01
申请号：EP88113248.4
申请日：1988-08-16
申请人： HOECHST JAPAN LIMITED
发明人： Jitsukawa, Tomofumi
IPC分类号： B01L11/00 , G01N33/543
CPC分类号： G01N33/54366 , B01L99/00 , B01L2400/0481
摘要： A device for pouring washing water into all wells of a multi-well plate comprises a washing water tank which is to be placed on a multi-well plate to be washed, and which (a) has in its bottom fine orifices to respectively confront the wells of the multi-well plate; (b) is tightly closeable, except for the orifices; (c) has at least a part of its constructional faces formed of an elastic synthetic resin material which is designed to be pressed down to force the washing water contained inside through the orifices to the outside; and (d) is so adapted that washing water can be supplied thereto.
摘要翻译：用于将洗涤水倒入多孔板的所有孔中的装置包括：待置于多孔板上的洗涤水箱，其中（a）在其底部具有细孔以分别面对多井板井; （b）除了孔口之外，密封紧密; （c）其至少一部分结构面由弹性合成树脂材料形成，该弹性合成树脂材料被设计成被压下以将包含在内部的洗涤水压迫到外部; 和（d）适于可以向其供应洗涤水。

87. 发明公开

EP0290006A2 Waste container insert for washing automated immunoassay apparatus probe 失效
标题翻译： Überlaufgefässeinbauzum Waschen der Sonde einer automatisiertenImmunoassaygeräts。
公开(公告)号：EP0290006A2
公开(公告)日：1988-11-09
申请号：EP88107154.2
申请日：1988-05-04
申请人： ABBOTT LABORATORIES
发明人： Kanewske, William Joseph III
IPC分类号： G01N35/00 , G01N1/00 , B01L11/00
CPC分类号： G01N35/1004
摘要： An article for washing automated immunoassay apparatus probe is provided in the form of a plug member with first and second chambers. The first chamber is defined by a inner wall and a bottom surface which when positioned below a probe of a clinical analysis apparatus provides for recirculation of liquid dispensed from the probe back along the outer surface of the probe to remove residual sample from the probe surface prior to conducting subsequent tests with the probe. In the preferred embodiment of the plug, the second chamber is provided with a plurality of passages for drainage of fluid to a reagent waste container which, in the preferred embodiment, incorporates the plug member at the orifice thereof.
摘要翻译：用于洗涤自动化免疫测定装置探针的物品以具有第一和第二腔室的塞子构件的形式提供。第一腔室由内壁和底部表面限定，当位于临床分析设备的探针下方时，可以沿着探针的外表面将从探针分配的液体再循环回去以从探针表面去除残留的样品用探针进行后续测试。在插头的优选实施例中，第二腔室设置有多个通道，用于将流体排放到试剂废物容器，在优选实施例中，该流体容纳在其孔口处的插塞构件。

88. 发明公开

EP0268348A3 Closed container opener 失效
标题翻译：关闭集装箱开启器
公开(公告)号：EP0268348A3
公开(公告)日：1988-11-02
申请号：EP87305862
申请日：1987-07-02
申请人： Warburg, Richard J.
发明人： Warburg, Richard J.
IPC分类号： B01L11/00 , B67B07/16
CPC分类号： B67B7/16
摘要： A closed container opener, particularly a microcentrifuge tube opener (10) is adapted to open a closed container, particularly a microcentrifuge tube (16) comprising a container (30) with an opening (32), and a lid (36) for the container, the lid having a lip projection (38) extending past the outer perimeter of the opening and a downwardly extending annular portion (34) shaped to sealing fit insude the opening. The opener comprises a base (14), having a recess (20) shaped to accept the lip projection, comprising a lower projection (22) below and adjacent the recess; and an upper projection (24) above and adjacent the recess. Both the lower projection and the upper projection are positioned to touch the lip and the lid, respectively. The lid can be moved from the container by positioning the lip in the recess and causing the lower projection to apply pressure to the lip away from the container and, at the same time, causing the upper projection to apply pressure to the tube at a position distant from the lip, in a direction towards the container.

89. 发明公开

EP0280965A2 Probe-gripper for automated sample preparation system 失效
标题翻译： Probengreiferfürein自动化Probenvorbereitungssystem。
公开(公告)号：EP0280965A2
公开(公告)日：1988-09-07
申请号：EP88102385.7
申请日：1988-02-18
申请人： MILLIPORE CORPORATION
发明人： Rabinovich, Joshua E.
IPC分类号： G01N35/06 , B01L11/00
CPC分类号： B01L9/50 , B65G47/908
摘要： A probe-gripper for automated sample preparation systems is disclosed, including a sample tube (12), an annular electrode (18), a barrel (40) surrounding the electrode, the barrel and the electrode being connected to capacitance measuring means, an annular elastomeric member (30) surrounding at least a poprtion of the electrode, the opposite end portions of the elastomeric member being secured to the electrode with an intermediate portion of the elastomeric member being free from the electrode to create an inflatable bladder, and passageways extending lengthwise of the probe to conduct pressurized fluid to the bladder to expand and contract it between gripping and release positions.
摘要翻译：公开了一种用于自动化样品制备系统的探针夹具，包括样品管（12），环形电极（18），围绕电极的筒体（40），筒体和电极连接到电容测量装置，环形弹性体构件（30）围绕至少一个电极，弹性体构件的相对端部固定到电极，弹性构件的中间部分没有电极以产生可充气气囊，并且纵向延伸的通道的探针，以将加压流体引导到膀胱以在夹紧位置和释放位置之间膨胀和收缩。

90. 发明公开

EP0268348A2 Closed container opener 失效
标题翻译： Vorrichtung zumÖffnenvon verschlossenenBehältern。
公开(公告)号：EP0268348A2
公开(公告)日：1988-05-25
申请号：EP87305862.2
申请日：1987-07-02
申请人： Warburg, Richard J.
发明人： Warburg, Richard J.
IPC分类号： B01L11/00 , B67B7/16
CPC分类号： B67B7/16
摘要： A closed container opener, particularly a microcentrifuge tube opener (10) is adapted to open a closed container, particularly a microcentrifuge tube (16) comprising a container (30) with an opening (32), and a lid (36) for the container, the lid having a lip projection (38) extending past the outer perimeter of the opening and a downwardly extending annular portion (34) shaped to sealing fit insude the opening. The opener comprises a base (14), having a recess (20) shaped to accept the lip projection, comprising a lower projection (22) below and adjacent the recess; and an upper projection (24) above and adjacent the recess. Both the lower projection and the upper projection are positioned to touch the lip and the lid, respectively. The lid can be moved from the container by positioning the lip in the recess and causing the lower projection to apply pressure to the lip away from the container and, at the same time, causing the upper projection to apply pressure to the tube at a position distant from the lip, in a direction towards the container.
摘要翻译：封闭的容器开启器，特别是微量离心管开启器（10）适于打开密封容器，特别是包括具有开口（32）的容器（30）的微量离心管（16）和用于容器的盖子（36），所述盖具有延伸穿过所述开口的外周边的唇突起（38）和成形为密封配合的向下延伸的环形部分（34）使所述开口成形。开启器包括底座（14），其具有成形为接收唇突起的凹部（20），包括在凹部下方并与其相邻的下突出部（22）; 以及在凹部上方并与其相邻的上突起（24）。下突起和上突起都分别接触唇缘和盖。可以通过将唇部定位在凹部中并使下部突起对容器施加压力使盖子从容器移动，并且同时使上部突起在管子的位置施加压力远离嘴唇，朝向容器的方向。

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