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81. 发明公开

EP0819941A2 Reagent container and cover 失效
标题翻译： Reagenzbehältermit Deckel
公开(公告)号：EP0819941A2
公开(公告)日：1998-01-21
申请号：EP97202829.4
申请日：1992-02-21
申请人： Ciba Corning Diagnostics Corp.
发明人： Carey, Glen A. , Mann, Raymond A. , Lewis, Scott C. , Whitesel, Mary Beth , Polaniec, James P. , Woyansky, George J. , Pabst, Stefan R. , Klingshirn, Frank C.
IPC分类号： G01N35/02 , B01L3/00 , B01L9/00
CPC分类号： B01L3/508 , B01L2300/0854 , G01N21/76 , G01N35/0098 , G01N35/021 , G01N35/025 , G01N35/1002 , G01N35/1065 , G01N2035/00386 , G01N2035/00396 , G01N2035/00524 , G01N2035/00752 , G01N2035/0441 , G01N2035/0443 , G01N2035/0465 , G01N2035/0484 , G01N2035/0486 , G01N2035/1025 , Y10S215/01 , Y10S215/03 , Y10S215/08 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998 , Y10T436/119163 , Y10T436/25 , Y10T436/2575
摘要： Inter alia , a reagent container characterised in that it comprises:

(a) a bottom wall;
(b) a vertical side wall which defines an inner chamber;
(c) a top opening;
and
(d) at least one fin which is located in the said chamber for agitating fluid within the said chamber upon rotation of the said container about a vertical axis is disclosed, as is a cover for such a container characterised in that a cover for a container as claimed in any of claims 1 to 12 characterised in that it is made of an elastomeric material and comprises:

(a) a continuous side wall for enabling the cover to be applied to the mouth of a corresponding container in a sealing fit;
and
(b) a top wall which has at least one slit which maintains the sealing integrity of the cover while allowing access into the interior of the container by an aspirating and dispensing probe.
摘要翻译：特别地，一种试剂容器，其特征在于，其包括：（a）底壁; （b）限定内腔的垂直侧壁; （c）顶部开口; 并且（d）公开了至少一个翅片，其位于所述腔室中，用于在所述容器围绕垂直轴旋转时搅拌所述腔室内的流体，以及用于这种容器的盖子，其特征在于， 10.根据权利要求1至12中任一项所述的容器，其特征在于，其由弹性体材料制成，并且包括：（a）连续侧壁，用于使所述盖能够以密封配合施加到相应容器的口部; 和（b）具有至少一个狭缝的顶壁，其保持盖的密封完整性，同时允许通过抽吸和分配探针进入容器的内部。小号

82. 发明公开

EP0803442A2 Hermetically sealed container with closure insert 无效
标题翻译： Hermetisch verschlossenerBehältermit Verschlusseinsatz
公开(公告)号：EP0803442A2
公开(公告)日：1997-10-29
申请号：EP97302783.2
申请日：1997-04-23
申请人： AUTOMATIC LIQUID PACKAGING, INC.
发明人： Weiler, Gerhard, H.
IPC分类号： B65D1/02
CPC分类号： B65D1/0238 , B65D51/18 , B65D2251/0006 , B65D2251/0075 , Y10S215/03
摘要： A flanged closure insert (44) is provided for the socket (32)of a hermetically sealed thermoplastic container (10). The closure insert (44) has an outwardly extending peripheral flange (62) that facilitates sealing of the container. The thermoplastic material of the container may be welded to the flange for an enhanced seal.
摘要翻译：为气密密封的热塑性容器（10）的插座（32）提供了一种带凸缘的封闭插件（44）。封闭插入件（44）具有有助于密封容器的向外延伸的周边凸缘（62）。容器的热塑性材料可以焊接到凸缘上以增强密封。

83. 发明公开

EP0783335A1 AN ADAPTOR FOR MEDICINE BOTTLE 失效
标题翻译：用转接器和一个药瓶
公开(公告)号：EP0783335A1
公开(公告)日：1997-07-16
申请号：EP94919360.0
申请日：1994-06-06
申请人： Schraga, Steven
发明人： Schraga, Steven
IPC分类号： A61J1 , A61M5
CPC分类号： A61J1/2096 , A61J1/201 , A61J1/2065 , A61M2205/583 , A61M2205/585 , Y10S215/03
摘要： For interconnecting a syringe (12) with a barrel (24) and needle to a bottle (14) of medicine wherein the bottle (14) has a generally cylindrical cap (16) with a central target zone (18) of relatively small diameter to be pierced by the needle (14), wherein the adaptor (26) includes a body having a first end with a truncated cone-shaped mouth (34) converging from the first end and an opposite end with a recess sized to receive the bottle cap, the cone-shaped surface (34) of the mouth being adapted to guide the needle (14) into generally co-axial alignment with the bottle and toward the target zone of the bottle cap.

84. 发明公开

EP0766975A1 Spritze für medizinische Zwecke 失效
标题翻译：注射器用于医疗目的
公开(公告)号：EP0766975A1
公开(公告)日：1997-04-09
申请号：EP96109807.6
申请日：1996-06-19
申请人： Arzneimittel GmbH Apotheker Vetter & Co. Ravensburg
发明人： Vetter, Helmut , Otto, Thomas
IPC分类号： A61M5/34
CPC分类号： A61M5/34 , A61M5/3134 , A61M5/5086 , A61M2005/3104 , A61M2005/3106 , A61M2005/312 , Y10S215/03 , Y10S604/905
摘要： Die Spritze für medizinische Zwecke ist mit einem am Zylindermundstück (1) des Spritzenzylinders (2) angesetzten, durch ein Verschlußteil (6) in Form von beispielsweise einem Tip-Cap bis zum Gebrauch der Spritze verschlossenen Nadelansatzstück (3) versehen, das zum Anbringen einer Kanüle eingerichtet ist. Das Nadelansatzstück (3) ist durch eine Überwurfkappe (4) am Zylindermundstück (1) gehalten und dicht mit dem Spritzenzylinder (2) verbunden. Die Überwurfkappe (4) ist durch einen aufgeschobenen und an ihr einrastenden Sicherungsring (9) unlösbar am Zylindermundstück (1) fixiert. Der Sicherungsring (9) trägt eine fest angeschlossene, aber abtrennbar ausgebildete Sicherungskappe (7), die das Nadelansatzstück (3) sowie das Verschlußteil (6) umschließt und aus einem im wesentlichen hohlzylindrischen Körper besteht, der an seiner dem Spritzenzylinder (2) abgewandten Ende zumindest teilweise durch eine Stirnwand (7.1) geschlossen ist. Die Sicherungskappe (7) und der Sicherungsring (9) bilden zwischen sich einen Ringspalt (8) und sind über mehrere Verbindungsstege (10) miteinander verbunden, wobei zwischen jeweils zwei Verbindungsstegen (10) wenigstens ein Distanzteil (11) angeordnet ist, das an der Sicherungskappe (7) oder am Sicherungsring (9) fest angeschlossen ist und dessen freies Ende dem Sicherungsring (9) oder der Sicherungskappe (7) anliegt oder mit geringem Abstand gegenübersteht.
摘要翻译：用于医疗目的的注射器是下一个与气缸烟嘴（1）的注射器筒（2）由封闭件（6）在例如末端帽的形式，直到使用注射器提供密封针毂（3），所述一个用于安装布置套管。针毂（3）通过保持帽（4）在汽缸烟嘴（1）和紧密地保持到注射器筒（2）。保持帽（4）和固定用推迟其接合锁定环（9）不可拆卸地在汽缸烟嘴（1）。锁定环（9）带有一个固定连接，但可割断形成固定帽（7），其包围所述针安装部（3）和封闭件（6）和包括一个基本中空的圆柱体的，从所述注射器筒背对的端部（2）至少部分地由端壁（7.1）被关闭。所述固定盖（7）和所述保持环（9）在它们之间形成一个环形间隙（8）和连接到彼此的多个连接片（10），其特征在于，两个相应的连接片（10）之间的至少一个间隔件（11）布置，这在固定帽（7）或固定环（9）被牢固地连接，并且其自由端邻接所述卡环（9）或所述固定盖（7）或具有小的距离上相对。

85. 发明公开

EP0765653A1 Vial having a resealable membrane assembly activated by a medical delivery device 失效
标题翻译： Phiole mit wiederverschliessbare Membrananordnung aktiviert durch eine medizinische Abgabevorrichtung
公开(公告)号：EP0765653A1
公开(公告)日：1997-04-02
申请号：EP96114816.0
申请日：1996-09-16
申请人： Becton Dickinson and Company
发明人： Grimard, Jean-Pierre
IPC分类号： A61J1/00
CPC分类号： A61J1/2096 , A61J1/2037 , Y10S215/03
摘要： A resealable assembly for a container such as a bottle or vial (10) featuring a membrane (40) for selectively opening or sealing a fluid path between the bottle (10) and a medical delivery device (60) introduced into the assembly. The assembly includes a body (22) disposed on said bottle (10) and a luer connector hub (32) which may be separately provided with the body (22) or formed integrally therewith. The luer connector hub (32) features a connector end (34) open for access by the medical delivery device, and an opposed end (36) which is disposed for fluid communication with the open top of the bottle (10). A membrane (40), preferably formed from an elastomeric material, is secured across both the opposed end (36) of the luer connector hub (32) and the open top of the bottle (10) and may be retained between the top surface of the bottle (10) and the body (22). The membrane (40) preferably includes a central area (42) sealing the opposed end (36) of the luer connector hub (32) from the open top of the bottle (10) with one or more fluid openings (44) defined on a portion of the membrane (40) outside of the central area (42). A force exerted on the central area (42) by the medical delivery device (60) deflects the membrane (40) towards the interior of the vial (10), urging the membrane (40) from sealing contact with the body (10) and, hence, opening the fluid path between the interior of the bottle (10) and the medical delivery device (60). The central area (42) may display one or more fluid flow channels to facilitate fluid flow between the medical delivery device (60) and the bottle (10) as contact is made between the medical delivery device (60) and the central area (42) of the membrane (40). A sealing rib may be provided around a portion of the periphery of the luer connector hub (32) to enhance sealing contact between the membrane (40) and the luer connector hub (32).
摘要翻译：用于诸如瓶或小瓶（10）的容器的可再密封组件，其特征在于用于选择性地打开或密封引导到组件中的瓶子（10）和医疗输送装置（60）之间的流体路径的膜（40）。所述组件包括设置在所述瓶子（10）上的主体（22）和可与所述主体（22）分开设置或与其整体形成的鲁尔连接器毂（32）。路厄尔连接器毂（32）具有一个用于由医疗输送装置进入的连接器端部（34），以及设置成与瓶子（10）的开口顶部流体连通的相对端部（36）。优选由弹性体材料形成的膜（40）被固定在路厄尔连接器毂（32）的相对端（36）和瓶（10）的开口顶部之间，并且可以保持在瓶子（10）和主体（22）。膜（40）优选地包括中心区域（42），其将鲁尔连接器毂（32）的相对端（36）与瓶（10）的开口顶部密封，一个或多个流体开口（44）限定在所述膜（40）的部分在所述中心区域（42）的外部。通过医疗输送装置（60）施加在中心区域（42）上的力使膜（40）朝向小瓶（10）的内部偏转，迫使膜（40）与主体（10）密封接触，并且因此，打开瓶子（10）的内部和医疗输送装置（60）之间的流体路径。当在医疗输送装置（60）和中央区域（42）之间进行接触时，中心区域（42）可以显示一个或多个流体流动通道以便于医疗输送装置（60）和瓶子（10）之间的流体流动）的膜（40）。可以围绕鲁尔连接器毂（32）的周边的一部分设置密封肋，以增强膜（40）和路厄尔连接器毂（32）之间的密封接触。

86. 发明授权

EP0504697B1 Verschluss für Reagenzbehälter 有权
标题翻译：封闭的试剂容器
公开(公告)号：EP0504697B1
公开(公告)日：1997-01-22
申请号：EP92103972.3
申请日：1992-03-09
申请人： F. HOFFMANN-LA ROCHE AG
发明人： Bucheli, Rudolf
IPC分类号： G01N35/10 , B01L3/00 , B65D51/00
CPC分类号： B01L3/50825 , G01N35/1002 , G01N35/1079 , G01N2035/00435 , Y10S215/03

87. 发明授权

EP0485004B1 Vial 失效
标题翻译： Phiole
公开(公告)号：EP0485004B1
公开(公告)日：1996-03-06
申请号：EP91202754.7
申请日：1991-10-24
申请人： DUPHAR INTERNATIONAL RESEARCH B.V
发明人： Portengen, Arnoldus F., c/o Octrooibureau Zoan BV.
IPC分类号： A61J1/06
CPC分类号： A61J1/06 , Y10S215/03

88. 发明公开

EP0559895A1 ALBUMIN PREPARATION AND PRESERVATION THEREOF 无效
标题翻译： ALBUMINZUBEREITUNG UND DEREN HALTBARMACHUNG。
公开(公告)号：EP0559895A1
公开(公告)日：1993-09-15
申请号：EP91920822.3
申请日：1991-11-29
申请人： THE GREEN CROSS CORPORATION
发明人： INOUE, Masahiro, The Green Cross Cor. Yodogawa , ITO, Hirokazu, The Green Cross Corp. Yodogawa , TOMIOKA, Shinji, The Green Cross Corp. Yodogawa , YABUSHITA, Sadao, The Green Cross Corporation , IKARIYA, Koei, The Green Cross Corporation , FURUTA, Koichi, The Green Cross Corp. Yodogawa
IPC分类号： A61K37/02 , C07K15/06
CPC分类号： C07K14/76 , Y10S215/03
摘要： A highly safe albumin preparation which can be preserved while preventing the release of aluminum from the container to thereby keep the aluminum content very low, by preserving an aqueous albumin solution in a soft glass container dealkalized by treating with, for example, sulfur dioxide gas or an ammonium sulfate solution instead of the conventional hard glass container which releases aluminum which has been believed to cause various diseases such as dialysis dementia, bone diseases, hypochromic anemia or Alzheimer's disease.
摘要翻译：一种高度安全的白蛋白制剂，其可以通过在例如二氧化硫气体处理脱碱性的软玻璃容器中保存白蛋白水溶液，同时防止铝从容器中释放，从而保持铝含量非常低一种硫酸铵溶液代替已经被认为引起各种疾病如透析性痴呆，骨病，低色素性贫血或阿尔茨海默病的铝的常规硬玻璃容器。

89. 发明公开

EP0552412A1 Cell culture vessels having interior ridges 失效
标题翻译： Zellkulturgefässemit Innenrippen。
公开(公告)号：EP0552412A1
公开(公告)日：1993-07-28
申请号：EP92116348.1
申请日：1992-09-24
申请人： Corning Incorporated
发明人： O'Connell, Dennis Malcolm, Corning Inc. , Paris, Martin Stephen, Corning Inc.
IPC分类号： C12M1/24
CPC分类号： C12M23/08 , C12M25/06 , Y10S215/03
摘要： The disclosed invention relates generally to laboratory ware, and specifically to laboratory ware and method for cultivating biological cell cultures within the laboratory ware. Cell culture vessels are disclosed providing enhanced cell yields for epithelial-like cell lines, and a more in-vivo like cell growing environment for fibroblast-like cell lines. A representative flask and dish including a plurality of grooves, or valleys, residing between ridges substantially covering the interior of preferably the bottom wall of the flask and dish is disclosed. The preferred ridges have a radius between 0.1 and 0.5 millimeters and range from 0.2 to 2.0 millimeters in height, and are spaced apart from each other within the range of 0.2 to 2.5 millimeters.
摘要翻译：所公开的发明一般涉及实验室器具，具体涉及用于在实验室器皿内培养生物细胞培养物的实验室器具和方法。公开了细胞培养容器，其提供上皮细胞系的增强的细胞产量，以及用于成纤维细胞样细胞系的更多体内样细胞生长环境。公开了一种代表性的烧瓶和盘，其包括位于基本上覆盖烧瓶和盘的底壁的内部的脊之间的多个凹槽或谷。优选的脊的半径在0.1和0.5毫米之间，范围是从0.2到2.0毫米的高度，并且在0.2到2.5毫米的范围内彼此间隔开。

90. 发明公开

EP0518191A3 Sterilizable hermetically-sealed substantial glass container and method for producing the container 失效
标题翻译：不可消毒的密封性物质玻璃容器及其制造方法
公开(公告)号：EP0518191A3
公开(公告)日：1993-07-28
申请号：EP92109324.1
申请日：1992-06-03
申请人： PPG INDUSTRIES, INC.
发明人： Betts, Ronald Eugene , Savage, Douglas Robert , Shane, Debra Jean
IPC分类号： B01L3/00 , B65D51/00 , G01N33/48 , B01J13/02
CPC分类号： B65D51/002 , B01L3/508 , B01L3/50825 , B01L2200/148 , Y10S215/03
摘要： A hermetically sealed vial for liquids is provided by the present invention. The liquid can be a calibrant or a reference fluid for gas analysis where the liquid has dissolved gas or medication or medicaments. The vial is a glass container means with at least one opening. The dimensions of the opening range from that which is just effective for the addition and removal of fluids to that which is the smallest side of the container. A flange circumferentially extends about the opening. The vial has the liquid that does not fill the vial to leave room for a head space. The head space is present in an amount of the volume percent of the vial ranging from 1 to 99 compared to the amount of the liquid. The vial is sealed with an air impermeable bilaminate seal comprised of an adhesive polymer contacting the vial and a metal surface facing externally from the vial. Before the vial is sealed by heat or induction sealing a securing means like a cap or chemical coupling agents are used to hold the seal on the vial. When the cap is a snap cap a gasket can be present between the cap and the seal. The vials can be sterilized and processed as a plurality of vials during heat and induction sealing and optionally sterilization depending on the application.

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