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71. 发明授权

EP2715368B1 TSH IMMUNOASSAYS AND PROCESSES FOR PERFORMING TSH IMMUNOASSAYS IN THE PRESENCE OF ENDOGENOUS CONTAMINANTS IN RESTRICTED WASH FORMATS 有权
标题翻译： TSH免疫测定和在限制性洗涤格式中存在内源性污染物时进行TSH免疫测定的过程
公开(公告)号：EP2715368B1
公开(公告)日：2018-02-14
申请号：EP11793964.5
申请日：2011-11-29
申请人： Abbott Point Of Care, Inc.
发明人： WANG, Dan , COLLIER, Gordon, Bruce , SKINNER, Joseph, P. , RUAN, Qiaoqiao , TETIN, Sergey
IPC分类号： G01N33/577 , G01N33/53 , G01N33/76 , G01N33/543
CPC分类号： G01N33/76 , B01L3/50273 , B01L3/502738 , C07K16/26 , C07K2317/33 , G01N33/5302 , G01N33/543 , G01N33/74 , G01N2333/59
摘要： The invention relates to low wash Thyroid Stimulating Hormone (TSH) immunoassays using an ELISA sandwich assay having limited or no wash step between the antigen capture, detection antibody addition and substrate introduction steps. This invention exhibits low cross reactivity with biologically similar interfering cross reacting species, such as Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH) and Chorionic Gonadotropin (CG).

72. 发明授权

EP2580591B1 MAGNETIC BEADS FOR REDUCING LEUKOCYTE INTERFERENCE IN IMMUNOASSAYS 失效
标题翻译：用于减少免疫细胞中白细胞干扰的磁珠
公开(公告)号：EP2580591B1
公开(公告)日：2017-08-23
申请号：EP11729225.0
申请日：2011-06-14
申请人： Abbott Point of Care Inc.
发明人： CAMPBELL, John Lewis Emerson , DAVIS, Graham
IPC分类号： G01N33/543
CPC分类号： G01N33/54326 , Y10T436/25125

73. 发明授权

EP2715356B1 TSH IMMUNOASSAYS EMPLOYING SCAVENGING REAGENTS FOR CROSS-REACTING ENDOCRINE GLYCOPROTEIN HORMONE ANALOGUES 失效
标题翻译：使用清除试剂交叉内分泌内分泌糖蛋白类激素类似物的TSH免疫试剂
公开(公告)号：EP2715356B1
公开(公告)日：2017-04-26
申请号：EP11793965.2
申请日：2011-11-29
申请人： Abbott Point of Care Inc.
发明人： COLLIER, Gordon Bruce , OMAKOR, John Emegbero
IPC分类号： G01N33/543 , G01N33/577 , G01N33/76
CPC分类号： G01N33/74 , G01N33/53 , G01N33/54326 , G01N33/76 , G01N2333/59 , Y10S436/825

74. 发明授权

EP2601526B1 MAGNETIC IMMUNOSENSOR AND METHOD OF USE 有权
标题翻译：磁传感器与使用及其方法免疫
公开(公告)号：EP2601526B1
公开(公告)日：2016-12-21
申请号：EP11748815.5
申请日：2011-08-05
申请人： Abbott Point Of Care, Inc.
发明人： MILLER, Cary James , HU, Jinghua
IPC分类号： G01N27/74 , G01N33/543 , B01L3/00
CPC分类号： G01N33/54326 , B01L3/502761 , B01L2200/0684 , B01L2300/0645 , B01L2300/0816 , B01L2400/043 , B01L2400/0481 , B01L2400/0683 , B01L2400/0688 , G01N27/745 , G01N33/5438
摘要： The present invention provides apparatus and methods for the rapid determination of analytes in liquid samples by immunoassays incorporating magnetic capture of beads on a sensor capable of being used in the point-of-care diagnostic field.

75. 发明授权

EP2600973B1 IMMUNOASSAY METHOD AND DEVICE WITH MAGNETICALLY SUSCEPTIBLE BEAD CAPTURE 有权
标题翻译：免疫检测方法和设备中，利用磁珠为基础的亲和柱
公开(公告)号：EP2600973B1
公开(公告)日：2016-05-25
申请号：EP11746727.4
申请日：2011-08-05
申请人： Abbott Point Of Care, Inc.
发明人： MILLER, Cary James
IPC分类号： B01L3/00 , G01N33/543
CPC分类号： G01N33/54326 , B01L3/502761 , B01L2200/0668 , B01L2400/043 , B01L2400/0487 , G01N33/5438

76. 发明公开

EP2994752A1 METHOD AND APPARATUS FOR DETERMINING HEMOGLOBIN BASED PARAMETERS IN AN UNLYSED BLOOD SAMPLE 审中-公开
标题翻译：方法和设备，用来确定基于血红蛋白参数的血液样本未溶解
公开(公告)号：EP2994752A1
公开(公告)日：2016-03-16
申请号：EP14755436.4
申请日：2014-05-09
申请人： Abbott Point Of Care, Inc.
发明人： UNFRICHT, Darryn W. , MUELLER, Cord , WARDLAW, Stephen C.
IPC分类号： G01N33/49 , G06T7/00
CPC分类号： G01N33/721 , G01N15/06 , G01N21/03 , G01N21/5907 , G01N33/49 , G01N33/726 , G01N33/80 , G01N2015/0065 , G01N2021/0346 , G01N2021/3144 , G01N2021/5934 , G01N2021/5957 , G01N2021/5988 , G01N2333/805 , G06K9/00134
摘要： A method and apparatus for determining hemoglobin concentration is provided. A method aspect includes the steps of: a) depositing an unlysed, substantially undiluted blood sample into an analysis chamber adapted to quiescently hold the sample for analysis; b) imaging the sample in a region of the analysis chamber where the height of the chamber is no more than about twenty microns (20μ) or no less than about two microns (2μ), to produce image signals representative of the optical density of the imaged region; c) determining a sample representative optical density value using the image signals representative of the optical density of the imaged region; and d) determining the hemoglobin concentration of the sample using the sample representative optical density value.
摘要翻译：提供了一种用于确定采矿血红蛋白浓度的方法和装置。一种方法方面包括以下步骤：a）未裂解的，基本上未稀释的血液样本的沉积到在分析腔室angepasst静止地保持用于分析的样品; B）成像在分析腔室的区域中的样品，其中所述腔室的高度为不大于约20微米（20μ）或不小于约2微米（2μ）以上，以产生代表的光密度的图像信号成像区域; c）中确定的采矿使用代表所述成像区域的光密度的图像信号的样本代表光密度值; 和d）确定的采矿使用样品代表光密度值样品的血红蛋白浓度。

77. 发明公开

EP2973098A2 MANAGEMENT SYSTEM FOR POINT OF CARE TESTING 有权
标题翻译：管理系统的护理点检
公开(公告)号：EP2973098A2
公开(公告)日：2016-01-20
申请号：EP14717579.8
申请日：2014-03-12
申请人： Abbott Point Of Care, Inc.
发明人： GLAVINA, Paul , TIRINATO, Jody Ann , EMERIC, Pierre , MOLLOY, Dan , WEBER, Maureen , FETTERS, Christopher
IPC分类号： G06F19/00 , G06Q10/06
摘要： The present invention relates to a method and system for quality compliance, system and operator verification, and process management for point of care biological sample testing systems used in hospitals and other medical delivery environments. Specifically, the present invention may be directed to a computing device configured to generate a plurality of attributes configured to assess a competency level of an operator to operate at least one sample testing instrument, obtain operator derived data pertaining to the operator's ability to operate the at least one sample testing instrument, and determine a competency level of the operator for the at least one sample testing instrument based the plurality of attributes and the operator derived data.

78. 发明公开

EP2939023A1 APPARATUS AND METHOD FOR IDENTIFYING A HOOK EFFECT AND EXPANDING THE DYNAMIC RANGE IN POINT OF CARE IMMUNOASSAYS 审中-公开
标题翻译： DEVICE AND METHOD FOR识别钩状效应和扩展动态范围免疫测定看护中心，
公开(公告)号：EP2939023A1
公开(公告)日：2015-11-04
申请号：EP13822067.8
申请日：2013-12-27
申请人： Abbott Point Of Care, Inc.
发明人： WEISS, Wenda , NGUYEN, Linda , CAMPBELL, John , SMITH, James , DOWELL, Barry, Lee
IPC分类号： G01N33/53 , G01N33/543
CPC分类号： G01N33/54366 , G01N33/5306 , G01N33/5438 , G01N33/54393
摘要： The present invention relates to systems and methods for the rapid in situ determination of the existence of a hook effect and expansion of the dynamic range of a point of care immunoassay. For example, a system for identifying a hook effect and expanding the dynamic range of an immunoassay is provided that may include a primary sensor having first immobilized antibodies that may be configured to generate a first signal based on a presence or absence of a target analyte in a sample. The system may further include an attenuated sensor having second immobilized antibodies at a reduced concentration relative to a concentration of the first immobilized antibodies on the primary sensor and that may be configured to generate a second signal based on the presence or absence of the target analyte in the sample. The system may further include a processor configured to determine a presence of a hook effect in the immunoassay based on relative values of the first and second signals and optionally determine the target analyte concentration of the sample.
摘要翻译：本发明涉及一种用于在一个钩状效应和护理免疫测定的一个点的动态范围的扩大存在的原位测定的快速的系统和方法。对于实施例，用于识别钩状效应，扩大提供了一种免疫测定的动态范围的系统确实可以包括具有第一固定化抗体的主传感器也可以被配置成基于在存在或不存在的目标分析物以产生第一信号一个样本。该系统还可以包括在减毒传感器在浓度相对于在主传感器的第一固定化抗体的浓度的降低具有第二固定化抗体，也可以基于在存在或不存在所述目标分析物是被配置为产生第二信号样品。该系统可以包括进一步经配置以确定的矿井的基于所述第一和第二信号的相对值和任选确定性矿在免疫测定中的钩效果的存在目标分析物样品的浓度的处理器。

79. 发明公开

EP2932250A1 SELF CORRECTION FOR SPATIAL ORIENTATION AND MOTION OF PORTABLE CLINICAL TESTING DEVICES 有权
标题翻译：自我修正的空间定向和移动便携式临床测试装置
公开(公告)号：EP2932250A1
公开(公告)日：2015-10-21
申请号：EP13815617.9
申请日：2013-12-06
申请人： Abbott Point Of Care, Inc.
发明人： VANDERSLEEN, Gary , EMERIC, Pierre , WASSERMAN, Paul , SOMAN, Narendra , DAVIS, Graham
IPC分类号： G01N27/327 , B01L3/00 , G01N33/487 , G01N33/86 , G01N33/53
CPC分类号： G06F19/10 , G01N27/3273 , G01N27/3274 , G01N33/48785
摘要： The present invention covers the integration and utility of accelerometer features into a clinical analysis system. For example, measurement of dynamic acceleration and orientation of a blood-testing instrument with respect to Earth's gravitational field may be used to determine reliability of a test procedure and optionally to provide corrective elements thereof.
摘要翻译：本发明涵盖的结合和加速度特征效用到临床分析系统。对于实施例，动态加速并且相对于地球重力场血液 - 测试仪的取向的测量可以被用来对测试过程的确定性矿可靠性和任选以提供其矫正元件。

80. 发明授权

EP2281197B1 METHOD OF DETECTING VERY LOW LEVELS OF ANALYTE WITHIN A THIN FILM FLUID SAMPLE CONTAINED IN A THIN THICKNESS CHAMBER 有权
标题翻译：方法检测非常低的分析物水平在薄膜室含有薄膜流体样品
公开(公告)号：EP2281197B1
公开(公告)日：2015-09-02
申请号：EP09730905.8
申请日：2009-04-02
申请人： Abbott Point Of Care, Inc.
发明人： WARDLAW, Stephen, C. , LEVINE, Robert, A.
IPC分类号： G01N33/543 , G01N33/58 , B82Y15/00
CPC分类号： G01N33/588 , B82Y15/00 , G01N33/54366

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