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    • 69. 发明公开
    • ADSORBENTS FOR ORAL ADMINISTRATION, REMEDIES OR PREVENTIVES FOR KIDNEY DISEASES AND REMEDIES OR PREVENTIVES FOR LIVER DISEASES
    • 对于口服,代理人接受治疗或肾脏疾病的预防吸附和手段用于治疗或预防肝脏疾病
    • EP1500397A4
    • 2005-03-30
    • EP03770095
    • 2003-10-31
    • KUREHA CHEMICAL IND CO LTD
    • SONOBE NMORIMOTO SYOSHIHARA HHANATSUKA HIROYUKIARAKAWA MAKOTO
    • A61K33/44A61P1/16A61P13/12A61P39/02
    • A61K33/44
    • An adsorbent for oral administration characterized by comprising a spherical active carbon which is produced with the use of a thermosetting resin as a carbon source and has a diameter of from 0.01 to 1 mm and a specific surface area determined in accordance with Langmuir's adsorption equation of 1000 m /g or more. An adsorbent for oral administration characterized by comprising a surface-modified spherical active carbon which is produced with the use of a thermosetting resin as a carbon source and has a diameter of from 0.01 to 1 mm and a specific surface area determined in accordance with Langmuir's adsorption equation of 1000 m /g or more and carries 0.40 to 1.00 meq/g of acidic groups in total and 0.40 to 1.10 meq/g of basic groups in total. These adsorbents for oral administration scarcely adsorb useful components in vivo and have favorable performance of adsorbing toxic substances, i.e., showing advantageous selective adsorption properties.
    • 对于口服给药,通过包括由热固性树脂作为碳源制得的球形活性炭,worin的直径为特征的吸附剂为0.01至1mm,并用Langmuir的吸附方程开采的比表面积确定性为1000μm<2> / g的 以上; 并在吸附剂对于口服给药,通过包括由热固性树脂作为碳源制备的表面改性球状活性炭,worin的直径为特征的是12点01分至1毫米,由朗缪尔的吸附方程开采的比表面积确定性为1000μm<2 > / g以上,酸性基团的总量是0:40到1:00毫克当量/克,和碱性基团的总量为0:40至1:10毫克当量/克。 用于口服给药的吸附剂表现出有用的选择性吸附,就是那样,有用物质在本体上的吸附少,和有毒物质的更大的吸附力。