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61. 发明公开

EP1613425A1 DEHYDROGENATION REACTIONS IN NARROW REACTION CHAMBERS AND INTEGRATED REACTORS 审中-公开
标题翻译：在窄的反应室和集成REACTORS脱水反应
公开(公告)号：EP1613425A1
公开(公告)日：2006-01-11
申请号：EP04759141.7
申请日：2004-04-06
申请人： Velocys, Inc.
发明人： BROPHY, John, H. , TONKOVICH, Anna, Lee , ROBERTS, Gary , SCHMIDT, Matthew, B. , CHADWELL, G., Bradley
IPC分类号： B01J19/00 , C01B3/38
CPC分类号： F28D9/00 , B01F5/0475 , B01F5/0478 , B01F5/0483 , B01F13/0059 , B01F15/06 , B01F2215/0431 , B01J19/0093 , B01J2219/00835 , B01J2219/0086 , B01J2219/00862 , C07C5/333 , F28F3/08 , F28F3/12 , F28F2260/02 , Y10S585/92 , Y10S585/921 , Y10S585/925
摘要： Methods of dehydrogenating hydrocarbons to yield unsaturated compounds are described. Reactor configurations useful for dehydrogenation are also described. Hydrocarbons can dehydrogenationed, for relatively long periods of time-on-stream, in a reaction chamber having a dimension of 2 mm or less to produce H2 and an olefin. Techniques have been developed that reduce coke and allow stable, relatively long-term operation in small reactors.

62. 发明公开

EP1596750A2 METHOD AND DEVICE FOR DETERMINING POSITION OF DENTAL IMPLANTS 审中-公开
标题翻译：方法和设备，用于确定牙种植体中的地位
公开(公告)号：EP1596750A2
公开(公告)日：2005-11-23
申请号：EP04707994.2
申请日：2004-02-04
申请人： Dadi, Michel
发明人： Dadi, Michel
IPC分类号： A61C1/00
CPC分类号： A61C1/084 , A61C9/00
摘要： An accessory for use in aiding an oral surgeon to determine the optimum position and angle for a dental implant to be installed in a bone includes a probe assembly having one or more pairs of probe members pivotally mounted to each other about a pivot axis at their centers. Each pair of probe members is configured and dimensioned such that one end of the pair on one side of the pivot axis serves as a probe end to straddle the bone with their tips contacting the bone at opposed contact points thereon, and the opposite end of the pair on the opposite side of the pivot axis serves as a guide end in which the tips of the probe members are automatically located to indicate the thickness of the bone at the pair of opposed contact points. Also described are a kit including a plurality of such accessories, a tool for manually applying such accessories, and a method of using such accessories for use in determining the optimum position and angle for a dental implant.

63. 发明公开

EP1585828A2 VERDRÄNGUNGSASSAY ZUR DETEKTION VON LIGAT-LIGAND ASSOZIATIONSEREIGNISSEN 审中-公开
标题翻译：置换测试用于结扎配协会事件的检测
公开(公告)号：EP1585828A2
公开(公告)日：2005-10-19
申请号：EP02740235.3
申请日：2002-04-06
申请人： FRIZ Biochem Gesellschaft für Bioanalytik mbH
发明人： HARTWICH, Gerhard , FRISCHMANN, Peter , HAKER, Ute , WIEDER, Herbert
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6825 , C12Q2545/107
摘要： The invention relates to a method for detecting ligate-ligand association events, comprising the following steps: provision of a modified surface, whereby the modification consists in the binding of at least one kind of ligate; provision of signal-ligands; provision of a sample containing ligands; bringing a defined amount of signal-ligands into contact with the modified surface and bringing the sample into contact with the modified surface; detecting the signal-ligands, in addition to comparing the values obtained from the detection of the signal-ligands to the reference values.

64. 发明公开

EP1567664A2 FLUORESZENZ-QUENCHEN ZUR DETEKTION VON NUKLEINSÄURE-OLIGOMER-HYBRIDISIERUNGSEREIGNISSEN BEI HOHEN SALZ-KONZENTRATIONEN 审中-公开
标题翻译：荧光猝灭用于检测核酸寡聚体杂交事件在高盐浓度
公开(公告)号：EP1567664A2
公开(公告)日：2005-08-31
申请号：EP02802612.8
申请日：2002-11-08
申请人： FRIZ Biochem Gesellschaft für Bioanalytik mbH
发明人： HARTWICH, Gerhard , KRATZMÜLLER, Thomas , WIEDER, Herbert
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6818 , C12Q2563/137 , C12Q2565/101 , C12Q2565/549 , C12Q2527/137
摘要： The invention relates to a method for detecting nucleic acid oligomer hybridization events by fluorescence quenching, which comprises as a first step the provision of a modified surface. The modification of the surface consists in the binding of at least one type of modified nucleic acid oligomers 201, wherein said nucleic acid oligomers 201 are modified by at least one type of fluorophore 102 bound to it. The further steps of the inventive method are: providing a sample that includes nucleic acid oligomers, contacting said sample with the modified surface, adjusting a defined salt concentration of greater than 0,5 mole/l in the solution surrounding the modified nucleic acid oligomer, detecting the fluorescence of the fluorophore and comparing the detected fluorescence intensity with reference values.

65. 发明公开

EP1562695A2 MULTIPHASIC MICROCHANNEL REACTIONS 有权
标题翻译： MEHRPHASENMIKROKANALREAKTIONEN
公开(公告)号：EP1562695A2
公开(公告)日：2005-08-17
申请号：EP03777681.2
申请日：2003-10-17
申请人： BATTELLE MEMORIAL INSTITUTE
发明人： MONZYK, Bruce , BROPHY, John H.
IPC分类号： B01F5/00
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/00835 , B01J2219/00837 , B01J2219/0084 , B01J2219/00844 , B01J2219/0086 , B01J2219/00873 , B01J2219/00905 , B01J2219/00923 , C07B61/00 , C07C29/50 , C07C45/33 , C07C45/38 , C07C45/72 , C07C51/09 , C07C51/16 , C07C253/00 , C07C2601/14 , Y10T436/2575 , Y10T436/25875 , C07C49/403 , C07C57/04 , C07C53/126 , C07C255/16 , C07C35/08
摘要： Multiphasic reactions, especially those reactions using a phase transfer catalyst, are conducted in microchannel apparatus. Advantageously, these reactions can be conducted with two, planar microlayers of reactants in adjacent laminar flow streams. Microchannel apparatus and methods for conducting unit operations such as reactions and separations in microchannel apparatus is also described. Microchannel apparatus can provide advantages for controlling reactions and separating products, solvents or reactants in multiphase reactions.
摘要翻译：多相反应，特别是使用相转移催化剂的那些反应在微通道装置中进行。有利地，这些反应可以在相邻层流中的两个反应物的平面微层进行。还描述了用于进行单元操作的微通道装置和方法，例如微通道装置中的反应和分离。微通道装置可以在多相反应中提供控制反应和分离产物，溶剂或反应物的优点。

66. 发明公开

EP1552789A3 Efficient single photon emission imaging 审中-公开
标题翻译：高效单光子发射成像
公开(公告)号：EP1552789A3
公开(公告)日：2005-07-20
申请号：EP05000202.1
申请日：2005-01-07
申请人： Ultra Spect Ltd.
发明人： Oaknin, Jacob H. , Shwartz, Shoulamit C. , Ohana, Israel
IPC分类号： A61B6/00 , G01T1/164
CPC分类号： G06T11/006 , A61B6/037 , A61B6/4057 , A61B6/503 , A61B6/541 , A61B6/583 , G01T1/1644 , G06T2211/424
摘要： The invention relates to efficient single photon emission imaging. A method of shortening acquisition time for obtaining a reconstructed image of a portion (4) of a body (5) of a human patient who was administered with dosage of radiopharmaceutical substance radiating gamma rays, using SPECT (single photon emission computerized tomography), for determination of functional information thereon, comprises the steps of: (a) acquiring photons (3) emitted from said portion (4) of the body (5), by means of a detector (2) capable of converting the photons (3) into electric signals, the electric signals relating to minimal information required for obtaining a meaningful image; (b) processing said electric signals by a position logic circuitry (7) and thereby deriving therefrom data indicative of positions on said photon detector crystal (6), where the photons have impinged the detector (2); and reconstructing an image of a spatial distribution of the pharmaceutical substance within the portion of the body (5) by iteratively processing said data.

67. 发明公开

EP1552789A2 Efficient single photon emission imaging 审中-公开
标题翻译： Effiziente Einzelphotonemissionsbildgebung
公开(公告)号：EP1552789A2
公开(公告)日：2005-07-13
申请号：EP05000202.1
申请日：2005-01-07
申请人： Ultra Spect Ltd.
发明人： Oaknin, Jacob H. , Shwartz, Shoulamit C. , Ohana, Israel
IPC分类号： A61B6/00 , G01T1/164
CPC分类号： G06T11/006 , A61B6/037 , A61B6/4057 , A61B6/503 , A61B6/541 , A61B6/583 , G01T1/1644 , G06T2211/424
摘要： The invention relates to efficient single photon emission imaging. A method of shortening acquisition time for obtaining a reconstructed image of a portion (4) of a body (5) of a human patient who was administered with dosage of radiopharmaceutical substance radiating gamma rays, using SPECT (single photon emission computerized tomography), for determination of functional information thereon, comprises the steps of:

(a) acquiring photons (3) emitted from said portion (4) of the body (5), by means of a detector (2) capable of converting the photons (3) into electric signals, the electric signals relating to minimal information required for obtaining a meaningful image;
(b) processing said electric signals by a position logic circuitry (7) and thereby deriving therefrom data indicative of positions on said photon detector crystal (6), where the photons have impinged the detector (2); and
reconstructing an image of a spatial distribution of the pharmaceutical substance within the portion of the body (5) by iteratively processing said data.
摘要翻译：本发明涉及有效的单光子发射成像。一种缩短采集时间的方法，用于获得使用SPECT（单光子发射计算机断层摄影）照射伽马射线的放射性药物物质的剂量的人类患者的身体（5）的部分（4）的重建图像，确定其上的功能信息包括以下步骤：（a）通过能够将光子（3）转换成光子（3）的检测器（2）获取从所述主体（5）的所述部分（4）发射的光子（3）电信号，与获得有意义的图像所需的最小信息有关的电信号; （b）通过位置逻辑电路（7）处理所述电信号，从而由其导出指示所述光子检测器晶体（6）上的位置的数据，其中光子已经撞击了检测器（2）; 以及通过迭代地处理所述数据来重建所述体内（5）部分内的所述药物物质的空间分布的图像。

68. 发明公开

EP1535160A2 PARALLEL PROCESSING PLATFORM WITH SYNCHRONOUS SYSTEM HALT/RESUME 审中-公开
标题翻译：与同步系统暂停/恢复并行处理平台
公开(公告)号：EP1535160A2
公开(公告)日：2005-06-01
申请号：EP03787990.5
申请日：2003-08-12
申请人： Elta Systems Ltd.
发明人： GOSTYNSKI, Victor , DORF, Shaul
IPC分类号： G06F11/34
CPC分类号： G06F11/3632
摘要： A method for synchronous debugging of a parallel processing platform, the platform comprising a plurality of processors executing code, the code including one or more breakpoints to allow debugging of the code. The method comprises upon a processor reaching a breakpoint, propagating a halt command to all of the processors in the platform; thereby halting system execution synchronously to enable examination of the states of the processors.

69. 发明授权

EP1264167B1 VORRICHTUNG UND VERFAHREN ZUM NACHWEIS ORGANISCHER MOLEKÜLE IN EINER PROBENSUBSTANZ 有权
标题翻译：设备和方法有机分子在样本物质检测
公开(公告)号：EP1264167B1
公开(公告)日：2005-04-27
申请号：EP01913647.2
申请日：2001-02-15
申请人： Lossau, Harald, Dr.
发明人： HARTWICH, Gerhard , LOSSAU, Harald
IPC分类号： G01N21/64 , G01N27/26 , B01J19/00
CPC分类号： G01N21/6452 , B01J2219/00434 , B01J2219/00439 , B01J2219/00605 , B01J2219/00608 , B01J2219/00659 , B01J2219/00707 , B01J2219/00722 , B01J2219/00725 , B01J2219/00729 , B01J2219/00745 , B01J2219/0075 , C12Q1/6837 , C40B40/06 , C40B40/10 , C40B40/18 , C40B60/14
摘要： The invention relates to a device for detecting organic molecules, especially biomolecules and polymers, in a test substance. The inventive device comprises an examination system (300) consisting of an array of test sites (T) to which the test substance can be supplied, every test site being provided with specific probe molecules (320), an illumination system (100) for optically illuminating a sub-array of test sites (T) and a detection system (400) for identifying those test sites (T) whose probe molecules (320) interact with the organic molecules (350) to be detected. The illumination system (100) comprises an array of separately controlled illumination sources (B) that are disposed in such a manner that every test site (T) of the sub-array is correlated with at least one illumination source (B) illuminating substantially said test site.

70. 发明公开

EP1516597A1 DRUG ELUTING STENT 审中-公开
标题翻译：医药有限公司，ELUTIONSSTENT
公开(公告)号：EP1516597A1
公开(公告)日：2005-03-23
申请号：EP03739968.0
申请日：2003-06-25
申请人： Microport Medical (Shanghai) Co., Ltd.
发明人： ZHANG, Yi , WANG, Jianke , TANG, Zhirong , HE, Shuiying , ZHOU, Shunhua , GAO, Runlin , LI, Junfei , ZHANG, Ying , LUO, Qiyi
IPC分类号： A61F2/06
CPC分类号： A61L31/10 , A61F2/07 , A61F2002/075 , A61F2250/0067 , A61L31/048 , A61L31/16 , A61L2300/416 , A61L2300/61 , C08L27/12
摘要： The invention relates to a drug eluting stent and a method for making the stent. The stent comprises a stent body and coats covering on the stent body, it is characterized in that : 2-4 coats are provided on the surface of the stent body, wherein at least two coats are drug coats. The drug coats comprise 0.5-99% polymer by weight, 0-10% additive by weight and 0.5-99% active ingredient by weight. A primer layer is provided between the drug coats and the stent body. A compact control-releasing layer is also coated on the surface of the drug coats.
摘要翻译：本发明涉及药物洗脱支架和制造支架的方法。支架包括支架主体和覆盖在支架主体上的涂层，其特征在于：在支架主体的表面上提供2-4个涂层，其中至少两个涂层是药物涂层。药物涂层包含0.5-99重量％的聚合物，0-10重量％的添加剂和0.5-99重量％的活性成分。在药物涂层和支架体之间设置底漆层。也可以在药物外套的表面上涂布紧密的控制释放层。

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