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51. 发明公开

EP3047796A4 METHOD AND SYSTEM FOR IMAGE PROCESSING OF INTRAVASCULAR HEMODYNAMICS 有权转让
标题翻译： VERFAHREN UND SYSTEM ZUR BILDVERARBEITUNG VONINTRAVASKULÄRERHÄMODYNAMIK
公开(公告)号：EP3047796A4
公开(公告)日：2017-05-31
申请号：EP14846348
申请日：2014-09-19
申请人： NAT UNIV CORP ASAHIKAWA MEDICAL UNIV , INFOCOM CORP
发明人： KAMADA KYOSUKE , HAYASHI HIDEAKI
IPC分类号： A61B5/026 , A61B5/0265 , A61B5/0275 , A61B10/00 , G01N21/64
CPC分类号： A61B5/0261 , A61B5/0035 , A61B5/0071 , A61B5/0263 , A61B5/0265 , A61B5/0275 , A61B5/7278 , A61B2505/05 , A61B2576/02 , G01R33/56366 , G06T7/0012 , G06T2207/10016 , G06T2207/10048 , G06T2207/20221 , G06T2207/30104
摘要： [Problem] The present invention provides analysis technology relating to video data of a fluorescent contrast agent shot by a microscope during an operation, and addresses the problem of providing a method and system allowing information such as BV, BF and MTT, and vascular wall thickness, to be estimated by fluorescent contrast agent analysis, by applying perfusion analysis methods, which allow estimation of information such as BV, BF and MTT, to fluorescent contrast agent analysis. [Solution] The method for image processing of intravascular hemodynamics according to the present invention is characterized by shooting video using infrared light, wherein the object of shooting is a portion of a blood vessel injected with a standard amount of a fluorescent contrast agent; performing image analysis of a shape of a chronological change curve of intensity values which are image outputs from the video shooting; and calculating relative data for blood volume and blood flow based on results of the image analysis.
摘要翻译：发明内容本发明提供涉及在操作期间通过显微镜拍摄的荧光造影剂的视频数据的分析技术，并且解决了提供允许诸如BV，BF和MTT以及血管壁厚度等信息的方法和系统的问题，通过荧光造影剂分析，通过应用灌注分析方法进行估计，这些方法可以估计诸如BV，BF和MTT等信息，进行荧光造影剂分析。解决方案根据本发明的用于血管内血液动力学的图像处理的方法的特征在于使用红外光拍摄视频，其中拍摄对象是注射有标准量的荧光造影剂的血管的一部分; 执行作为来自视频拍摄的图像输出的强度值的时间变化曲线的形状的图像分析; 并且基于图像分析的结果计算血量和血流的相关数据。

52. 发明公开

EP2572638A4 MAGNETIC RESONANCE IMAGING APPARATUS AND MAGNETIC RESONANCE IMAGING METHOD 有权转让
标题翻译：磁共振磁共振成像
公开(公告)号：EP2572638A4
公开(公告)日：2017-05-10
申请号：EP11842125
申请日：2011-11-15
申请人： TOSHIBA MEDICAL SYS CORP
发明人： MIYAZAKI MITSUE
IPC分类号： G01R33/563 , A61B5/055
CPC分类号： G01R33/5635 , A61B5/0263 , A61B5/055 , A61B5/0555 , A61B5/7285 , G01R33/4833 , G01R33/543 , G01R33/5608 , G01R33/56366

53. 发明公开

EP3118644A1 REAL-TIME PROSPECTIVE MOTION CORRECTION FOR MRI 审中-公开
标题翻译： PROSPEKTIVE ECHTZEIT-BEWEGUNGSKORREKTURFÜRMRT
公开(公告)号：EP3118644A1
公开(公告)日：2017-01-18
申请号：EP16180003.2
申请日：2016-07-18
申请人： Siemens Medical Solutions USA, Inc. , Massachusetts General Hospital Corporation
发明人： Bhat, Himanshu , Cauley, Stephen Farman , Heberlein, Keith Aaron , Setsompop, Kawin , Tisdall, Matthew Dylan , Van Der Kouwe, Andre Jan Willem
IPC分类号： G01R33/54 , G01R33/561 , G01R33/567 , G01R33/56 , G01R33/563
CPC分类号： G01R33/56509 , G01R33/54 , G01R33/5602 , G01R33/5611 , G01R33/5616 , G01R33/5617 , G01R33/56341 , G01R33/56366 , G01R33/5676
摘要： A magnetic resonance (MR) method and system are provided for generating real-time prospective motion-corrected images using fast navigators. The real-time motion correction is achieved by using a 2D EPI navigator that is obtained using a simultaneous multi-slice blipped-CAIPI technique. The navigator parameters such as field of view, voxel size, and matrix size can be selected to facilitate fast acquisition while providing information sufficient to detect rotational motions on the order of several degrees or more and translational motions on the order of several millimeters or more. The total time interval for obtaining and reconstructing navigator data, registering the navigator image, and providing feedback to correct for detected motion, can be on the order of about 100 ms or less. This prospective motion correction can be used with a wide range of MR imaging techniques where the pulse sequences do not have significant intervals of "dead" time.
摘要翻译：提供磁共振（MR）方法和系统用于使用快速导航器生成实时预期的运动校正图像。通过使用使用同时多片片blipped-CAIPI技术获得的2D EPI导航器来实现实时运动校正。可以选择诸如视场，体素大小和矩阵大小的导航器参数以便于快速获取，同时提供足以检测几度或更多次的旋转运动的信息以及几毫米以上的平移运动。用于获取和重构导航器数据，登记导航器图像以及提供用于校正检测到的运动的反馈的总时间间隔可以在大约100ms或更少的量级上。这种前瞻性运动校正可用于广泛的MR成像技术，其中脉冲序列不具有显着的“死”时间间隔。

54. 发明公开

EP3052019A1 SYSTEM AND METHOD FOR MYOCARDIAL PERFUSION PATHOLOGY CHARACTERIZATION 有权
标题翻译： VERFAHREN ZUR CHARAKTERISIERUNG MYKARDIALER PERFUSIONSERKRANKUNGEN系统
公开(公告)号：EP3052019A1
公开(公告)日：2016-08-10
申请号：EP14780477.7
申请日：2014-10-01
申请人： Koninklijke Philips N.V. , Kings College London
发明人： BREEUWER, Marcel , CHIRIBIRI, Amedeo , NAGEL, Eike
IPC分类号： A61B5/055 , G01R33/563 , G06T7/00 , A61B5/026 , A61B6/03 , A61B6/00 , A61B8/06 , A61B8/08
CPC分类号： A61B5/055 , A61B5/0044 , A61B5/026 , A61B5/04017 , A61B5/0402 , A61B6/032 , A61B6/037 , A61B6/481 , A61B6/503 , A61B6/507 , A61B8/06 , A61B8/0883 , A61B8/481 , G01R33/5608 , G01R33/56366 , G06T7/0016 , G06T2207/10076 , G06T2207/30048 , G06T2207/30104
摘要： A method of characterizing myocardial perfusion pathology by analyzing a plurality of medical images of at least a portion of the heart of a subject of interest (20), acquired in a consecutive manner by a medical imaging modality (10), the method comprising steps of: sampling intensities of selected myocardial image positions from the plurality of medical images and assigning an index representing an order of acquisition to the respective sampled intensities of the myocardial image positions to obtain intensity curves (60); and—calculating an index number (64, 66) indicative of a spatio-temporal perfusion inhomogeneity or perfusion dephasing among at least a subset of myocardial segments of the plurality of myocardial segments, based on the obtained intensity curves (60); a system (52) for myocardial perfusion pathology characterization by analyzing a plurality of medical images by carrying out such method; a medical imaging modality (10) comprising such system (52); a software module (48) for carrying out such method.
摘要翻译：通过分析通过医学成像模态（10）以连续方式获取的感兴趣对象（20）的心脏的至少一部分的心脏的多个医学图像来表征心肌灌注病理学的方法，所述方法包括以下步骤：从所述多个医学图像中取出所选择的心肌图像位置的强度，并将表示采集次序的指标分配给心肌图像位置的相应采样强度，以获得强度曲线（60）; 以及计算指示在所获得的强度曲线（60）中基于所获得的强度曲线（60）在多个心肌节段的至少一个心肌节段的子集之间指示空间 - 时间灌注不均匀性或灌注去相位的指数（64,66）。用于通过执行这种方法分析多个医学图像的用于心肌灌注病理学表征的系统（52）; 包括该系统（52）的医学成像模式（10）; 用于执行这种方法的软件模块（48）。

55. 发明公开

EP2867657A4 TECHNIQUES, SYSTEMS AND MACHINE READABLE PROGRAMS FOR MAGNETIC RESONANCE 审中-公开
标题翻译：方法，系统和机器可读的方案磁
公开(公告)号：EP2867657A4
公开(公告)日：2016-05-11
申请号：EP13813129
申请日：2013-07-02
申请人： MILLIKELVIN TECHNOLOGIES LLC
发明人： KALECHOFSKY NEAL , HROVAT MIRKO
IPC分类号： G01N24/08 , G01R33/36 , G01R33/46 , G01R33/48 , G01R33/485 , G01R33/563
CPC分类号： G01R33/4608 , G01N24/08 , G01R33/3621 , G01R33/4616 , G01R33/4828 , G01R33/485 , G01R33/56308 , G01R33/56366

56. 发明公开

EP2886052A4 MAGNETIC RESONANCE IMAGING DEVICE 有权转让
标题翻译： VORRICHTUNG ZUR ABBILDUNG MAGNETISCHER RESONANZEN
公开(公告)号：EP2886052A4
公开(公告)日：2016-04-20
申请号：EP13837210
申请日：2013-09-17
申请人： TOSHIBA KK , TOSHIBA MEDICAL SYS CORP
发明人： ZHOU XIANGZHI , MIYAZAKI MITSUE , HOSHINO TSUTOMU
IPC分类号： A61B5/055
CPC分类号： A61B5/055 , A61B5/0044 , A61B5/0263 , A61B5/742 , G01R33/385 , G01R33/4833 , G01R33/5608 , G01R33/56366
摘要： A magnetic resonance imaging apparatus according to an embodiment includes a sequence controller (30) and a display controller (20). The sequence controller (30) performs, for multiple given times of different lengths, data acquisition for acquiring data on slices of a heart after the multiple given times since application of a tag pulse on a tag region. The display controller (20) displays multiple results of analysis of the data acquired for the multiple given times such that a relationship between the multiple given times and the slices can be identified.
摘要翻译：根据实施例的磁共振成像装置包括顺序控制器（30）和显示控制器（20）。顺序控制器（30）对于在标签区域上施加标签脉冲之后的多个给定时间之后，对于不同长度的多个给定时间执行用于获取心脏切片上的数据的数据采集。显示控制器（20）显示对于多个给定时间获取的数据的多个分析结果，使得可以识别多个给定时间和切片之间的关系。

57. 发明公开

EP2975545A1 METHOD AND SYSTEM FOR PATIENT-SPECIFIC MODELING OF BLOOD FLOW 有权
标题翻译：方法和系统特定患者的血流量建模
公开(公告)号：EP2975545A1
公开(公告)日：2016-01-20
申请号：EP15178021.0
申请日：2011-07-29
申请人： Heartflow, Inc.
发明人： TAYLOR, Charles, A. , FONTE, Timothy, A. , CHOI, Gilwoo , BAI, Ying , ZARINS, Christopher, K.
IPC分类号： G06F19/00 , A61B5/026
CPC分类号： A61B34/10 , A61B5/0035 , A61B5/004 , A61B5/0044 , A61B5/02 , A61B5/02007 , A61B5/02028 , A61B5/021 , A61B5/024 , A61B5/026 , A61B5/0263 , A61B5/029 , A61B5/055 , A61B5/1075 , A61B5/1118 , A61B5/22 , A61B5/4848 , A61B5/6852 , A61B5/7246 , A61B5/7275 , A61B5/7278 , A61B5/745 , A61B6/03 , A61B6/032 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/507 , A61B6/5205 , A61B6/5217 , A61B6/5229 , A61B8/02 , A61B8/04 , A61B8/06 , A61B8/065 , A61B8/481 , A61B8/5223 , A61B8/5261 , A61B34/25 , A61B2034/104 , A61B2034/105 , A61B2034/107 , A61B2034/108 , A61B2090/374 , A61B2090/3762 , A61B2090/3764 , A61B2576/00 , A61B2576/023 , A61M5/007 , G01R33/5601 , G01R33/5635 , G01R33/56366 , G06F17/10 , G06F17/5009 , G06F17/5018 , G06F19/00 , G06F19/12 , G06F19/26 , G06F19/321 , G06F19/324 , G06G7/60 , G06K9/00147 , G06K9/46 , G06K9/4604 , G06K9/52 , G06K9/6215 , G06K9/6267 , G06K9/6298 , G06K2009/4666 , G06T7/0012 , G06T7/0014 , G06T7/11 , G06T7/12 , G06T7/13 , G06T7/149 , G06T7/20 , G06T7/60 , G06T7/62 , G06T7/70 , G06T7/73 , G06T7/74 , G06T11/00 , G06T11/001 , G06T11/008 , G06T11/20 , G06T11/60 , G06T15/10 , G06T17/00 , G06T17/005 , G06T17/20 , G06T2200/04 , G06T2207/10012 , G06T2207/10072 , G06T2207/10081 , G06T2207/10088 , G06T2207/10104 , G06T2207/10108 , G06T2207/20036 , G06T2207/20124 , G06T2207/30048 , G06T2207/30104 , G06T2210/41 , G06T2211/404 , G16H10/40 , G16H10/60 , G16H30/20 , G16H30/40 , G16H50/30 , G16H50/50 , Y02A90/22 , Y02A90/26
摘要： Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

58. 发明公开

EP2967466A1 PERFUSION PHANTOM DEVICE 有权
标题翻译：灌注幻影器件
公开(公告)号：EP2967466A1
公开(公告)日：2016-01-20
申请号：EP14716372.9
申请日：2014-03-10
申请人： Kings College London
发明人： CHIRIBIRI, Amedeo , NAGEL, Eike , ZARINABAD NOORALIPOUR, Niloufar , WESOLOWSKI, Roman
IPC分类号： A61B6/00 , G01R33/58
CPC分类号： G09B23/286 , A61B6/583 , A61B2017/00716 , G01R33/56366 , G01R33/58 , G09B23/303
摘要： Uses of the device in quality control, validation or calibration of monitoring devices such as magnetic resonance (MR) or computerized tomography (CT) scanners, in teaching or training of machine operatives or for research purposes including for research into scanners, scanning techniques or reagents such as contrast agents used in such processes, form further aspects of the invention.
摘要翻译：本发明涉及一种用于再现体内流体灌注的幻象装置，所述装置包括可引入扫描仪的幻影器官，所述幻影器官包括壳体，在壳体中限定多个流体通道，适合具有不同的交叉 - 区域; 设置为向所有所述通道的第一端供应液体的供给管和用于从通道的另一端收集液体的装置。可替代地或另外地，该装置可以包括元件，该元件包括流体可以流过的幻影心脏，其中幻影心脏包括第一腔室和第二腔室，第一腔室代表右心房，第一腔室布置成从流体供应接收流体，第二腔室代表右心室其接收离开所述第一腔室的流体;第三腔室，其代表接收离开第二腔室的流体的左心房;以及第四腔室，其代表接收离开第三腔室的流体的左心室; 并且其中在第二腔室和第三腔室之间插入幻像胸腔系统。在机器操作员的教学或培训中或用于研究目的，包括用于研究扫描仪，扫描技术或试剂的设备在质量控制，磁共振（MR）或计算机断层摄影（CT）扫描仪等监测设备的质量控制，验证或校准中的用途例如在这些过程中使用的造影剂，形成本发明的其他方面。

59. 发明公开

EP2886052A1 MAGNETIC RESONANCE IMAGING DEVICE 有权转让
标题翻译：磁共振成像装置
公开(公告)号：EP2886052A1
公开(公告)日：2015-06-24
申请号：EP13837210.7
申请日：2013-09-17
申请人： Kabushiki Kaisha Toshiba , Toshiba Medical Systems Corporation
发明人： ZHOU, Xiangzhi , MIYAZAKI, Mitsue , HOSHINO, Tsutomu
IPC分类号： A61B5/055
CPC分类号： A61B5/055 , A61B5/0044 , A61B5/0263 , A61B5/742 , G01R33/385 , G01R33/4833 , G01R33/5608 , G01R33/56366
摘要： A magnetic resonance imaging apparatus according to an embodiment includes a sequence controller (30) and a display controller (20). The sequence controller (30) performs, for multiple given times of different lengths, data acquisition for acquiring data on slices of a heart after the multiple given times since application of a tag pulse on a tag region. The display controller (20) displays multiple results of analysis of the data acquired for the multiple given times such that a relationship between the multiple given times and the slices can be identified.
摘要翻译：根据实施例的磁共振成像设备包括序列控制器（30）和显示控制器（20）。序列控制器（30）针对在标签区域上施加标签脉冲后的多次给定时间之后，对于不同长度的多次给定时间执行用于获取关于心脏的切片的数据的数据采集。显示控制器（20）显示针对多个给定时间获取的数据的多个分析结果，从而可以识别多个给定时间与切片之间的关系。

60. 发明授权

EP2381840B1 REAL-TIME PERFUSION IMAGING AND QUANTIFICATION 有权
标题翻译：灌注成像和定量实时
公开(公告)号：EP2381840B1
公开(公告)日：2014-09-17
申请号：EP09775132.5
申请日：2009-11-23
申请人： Bracco Suisse SA
发明人： FRINKING, Peter , MERCIER, Laurent , ROGNIN, Nicolas , ARDITI, Marcel
IPC分类号： A61B5/055 , A61B6/00 , A61B8/00 , A61B8/06 , G01R33/28 , G01S7/52 , A61B8/08 , G01R33/563
CPC分类号： A61B5/055 , A61B6/504 , A61B6/507 , A61B8/06 , A61B8/481 , G01R33/563 , G01R33/56366

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