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41. 发明授权

EP1310303B1 Behälter für mehrere unterschiedliche bei der Durchführung eines Protokolls erforderlichen Reagenzien 有权
标题翻译：集装箱在协议所需的试剂执行几种不同
公开(公告)号：EP1310303B1
公开(公告)日：2005-12-14
申请号：EP02024763.1
申请日：2002-11-06
申请人： EPPENDORF AG
发明人： Richter, Jörg , von Beichmann, Boris
IPC分类号： B01L3/00
CPC分类号： G01N35/028 , B01L3/02 , B01L3/5085 , G01N35/1002 , G01N35/1079 , G01N2035/0436

42. 发明公开

EP1599287A1 VERFAHREN UND VORRICHTUNG ZUM KONTAKTIEREN EINER MIKROFLUIDIKSTRUKTUR 审中-公开
标题翻译：方法和设备，用于接触微
公开(公告)号：EP1599287A1
公开(公告)日：2005-11-30
申请号：EP04710344.5
申请日：2004-02-12
申请人： Cytocentrics CCS GmbH
发明人： KNOTT, Thomas , STETT, Alfred , SYGALL, Peter , VON STIPHOUT, Peter
IPC分类号： B01L3/00 , G01N35/10
CPC分类号： B01L3/502715 , B01J19/0093 , B01J2219/00783 , B01J2219/00891 , B01L3/022 , B01L2200/027 , B01L2400/0487 , G01N35/1011 , G01N35/1065 , G01N35/1079 , G01N2035/00158 , G01N2035/00237
摘要： The invention relates to a method and a device for contacting a microfluid structure (12). Said device comprises a receptacle (16) for the microfluid structure (12) and a contact unit (18). According to one aspect of the invention, the contact unit (18) encompasses at least one hollow needle (22, 24, 26) which is embodied so as to break through a layer (14) of elastic material that is provided on the microfluid structure (12).

43. 发明公开

EP1564179A1 Latch system for closed container sampling piercing station 审中-公开
标题翻译：锁定为插头穿刺设备的设备用于从密闭容器中取样
公开(公告)号：EP1564179A1
公开(公告)日：2005-08-17
申请号：EP05006776.8
申请日：2002-01-30
申请人： Beckman Coulter, Inc.
发明人： Goodale, David, L. , Katzmann, Steven, P. , Robins, William, M.
IPC分类号： B67B7/00 , G01N1/00 , G01N35/10
CPC分类号： G01N35/1079 , B01L3/50825 , B67B7/24 , G01N2035/00277 , Y10T83/0481
摘要： The invention relates to an apparatus for piercing container caps, having means for moving a blade (100) to pierce a cap of a container, and a latch assembly (12) for latching a device to prevent said container from being moved by friction with said blade (100) when said blade is being withdrawn from a pierced cap (9), wherein said latch assembly (12) comprises:

a trigger (18) movable between a latching position when said piercing blade (100) is being withdrawn from said pierced cap (9) and an unlatched position after said piercing blade (100) has been withdrawn from said pierced cap (9), and
an actuator (19) having teeth (22), wherein said actuator (19) is engaged with said trigger (18) and having locking means (24), such that when said trigger (18) moves to said latching position, said actuator (19) causes its teeth (22) matingly locked with fixed complementary teeth (23) to latch said alignment assembly (8), and when said trigger (18) moves to said unlatched position, said actuator (19) causes its teeth (22) to unlock from said fixed complementary teeth (23) to unlatch said alignment assembly (8).
摘要翻译：本发明涉及的装置用于刺穿容器盖，其具有用于移动的刀片（100）刺穿容器的盖，以及用于锁定装置，以防止所述容器从闩锁组件（12）的装置由摩擦移动与所述叶片（100），当所述叶片正在从刺穿的盖抽出（9），worin所述闩锁组件（12）包括：一个触发器（18）的闩锁位置，当所述刺穿刀片（100）可从所述抽出刺穿之间移动帽（9）和在所述穿刺叶片后未闩锁位置（100）已经从所述退出刺穿帽（9），以及致动器（19）具有齿（22），worin所述致动器（19）与所述扳机接合（ 18）以及具有锁定装置（24）检测做，当所述触发器（18）移动到所述闩锁位置时，所述致动器（19）使得其齿（22）与固定的互补齿（23）配合锁定至所述闩锁对准组件（ 8），并且当所述触发（18）移动到所述解锁位置时，所述致动器（19）使其齿（22），以从固定在所述互补齿（23）解锁，以解锁所述对准组件（8）。

44. 发明授权

EP0763739B1 METHOD AND APPARATUS FOR LIQUID TREATMENT UTILIZING DISPENSER 失效
标题翻译：方法和设备流体处理由分发手段
公开(公告)号：EP0763739B1
公开(公告)日：2005-06-01
申请号：EP96906085.4
申请日：1996-03-19
申请人： PRECISION SYSTEM SCIENCE CO., LTD.
发明人： TAJIMA, Hideji, Precision System Science Co., Ltd.
IPC分类号： G01N33/543 , G01N33/553 , G01N35/10
CPC分类号： G01N35/1065 , B01L3/0275 , B01L3/0279 , B01L7/52 , B01L2300/0681 , B01L2300/087 , B03C1/01 , B03C1/0332 , B03C1/0335 , B03C1/288 , B03C2201/18 , B03C2201/26 , G01N35/0098 , G01N35/10 , G01N35/1079 , G01N2035/0405 , G01N2035/103 , G01N2035/1053 , G01N2035/1055

45. 发明公开

EP1409981A2 CAP PIERCING STATION FOR CLOSED CONTAINER SAMPLING SYSTEM 有权
标题翻译： PLUG冬青设备技术从抽样封闭的容器
公开(公告)号：EP1409981A2
公开(公告)日：2004-04-21
申请号：EP01946506.1
申请日：2001-06-19
申请人： Beckman Coulter, Inc.
发明人： GOODALE, David, L. , ROBINS, William, M. , KATZMANN, Steven, P.
IPC分类号： G01N1/00
CPC分类号： G01N35/1079
摘要： A piercing station for piercing sample container caps or thick stoppers. The piercing station has a structural frame with two vertical guide rods. A carriage assembly is slidably mounted on the guide rods and is further driven to move up and down along the guide rods. The carriage assembly carries a blade holder, which in turn holds a piercing blade assembly. The blade assembly includes a center blade and two cross blades interlocked together, such that the blade assembly has a generally modified 'H'-shaped cross section for piercing a cap on the sample container. Lubricant left in or on the sample container cap by the piercing station reduces the force required by the sample probe to penetrate thick stoppers for sample aspiration and level sensing. The 'H'-shaped cut helps to equalize the pressure in the sample container during sampling, so that clot detection is more effective.

46. 发明授权

EP0725593B1 FLUID SAMPLE COLLECTION AND INTRODUCTION DEVICE 失效
标题翻译：设备验收和介绍液体样品
公开(公告)号：EP0725593B1
公开(公告)日：2004-04-07
申请号：EP94930783.9
申请日：1994-10-13
申请人： I-STAT CORPORATION
发明人： LAUKS, Imants R. , ROGERS, Joseph W.
IPC分类号： G01N1/00 , G01N33/483 , B01L3/00
CPC分类号： B01L9/065 , B01L3/502715 , B01L2200/027 , B01L2300/0809 , B01L2300/0838 , B01L2400/0406 , B01L2400/0481 , B01L2400/0487 , G01N35/1079
摘要： A device and method for collecting a fluid sample and introducing it into a sensing device for real time analysis includes a capillary tube (23), a reservoir chamber (24), a capillary support means (21), a housing (100) and a port (120).

47. 发明公开

EP1370359A1 MOYENS POUR L'EXTRACTION DE PRODUITS A ANALYSER ET LEURS APPLICATIONS EN DIAGNOSTIC ET ANALYSE 审中-公开
标题翻译：提取分析者的方法及其在诊断和分析应用
公开(公告)号：EP1370359A1
公开(公告)日：2003-12-17
申请号：EP02708442.5
申请日：2002-03-01
申请人： SCP Dosagene R & D
发明人： COMMERCON, Pierre , DELIOU, Henri-Pierre
IPC分类号： B01L3/14 , G01N1/00
CPC分类号： G01N35/1079 , B01L3/5021 , B01L2200/026 , B01L2300/049 , G01N2035/1032 , Y10T436/25375
摘要： The invention relates to means for extracting products to be analysed. Said means comprise a device for extracting one or more layers comprising the sought-after products or constituents from a test tube (1) containing numerous different adjacent or overlapping layers in a liquid medium forming a continuous or discontinuous density gradient (2). Said invention is characterised in that it comprises: a standard test tube (1), an extraction capillary or tube (3), which can be pre-positioned according to the layer to be extracted, and means for obtaining a laminar flow of one or more layers from the tube without suction, either by applying overpressure to the top of the liquid medium with a low-density liquid, gas or fluid or by exerting a centrifugal force. The invention can be used to extract one or more layers of constituents, for example, from a blood mixture.

48. 发明公开

EP1329705A3 Pipette- and cartridge-comprising set and related application methods 审中-公开
标题翻译：的移液管和药筒全面的系统及使用方法相关联的
公开(公告)号：EP1329705A3
公开(公告)日：2003-09-17
申请号：EP03075168.9
申请日：2003-01-17
申请人： Spark Holland B.V.
发明人： Hilhorst, Martinus Josephus , Ooms, Jan Albert
IPC分类号： G01N1/40 , B01L3/02
CPC分类号： B01L9/54 , B01L3/0217 , G01N1/40 , G01N1/405 , G01N35/1079 , G01N2035/1053 , Y10T436/2575
摘要： The invention relates to a set comprising, on the one hand, a pipette (12) having a pipette orifice (11) and, on the other hand, a cartridge (1). The cartridge comprises: a housing (2); a chamber, containing sorbent (5), provided in the housing; an inlet (8) that connects the chamber to the outside of the housing and that has an inlet orifice (10) on the outside of the housing; an outlet that connects the chamber to the outside of the housing; an inlet closure (9) that is permeable to fluid and impermeable to the sorbent, which inlet closure extends over the entire inlet passage; an outlet closure (6), such as a mesh, that is permeable to fluid and impermeable to the sorbent, which outlet closure extends over the entire outlet passage; wherein the pipette orifice can be accommodated in the inlet orifice. The invention furthermore relates to a method for applying the sample to a sorbent by means of a pipette. In addition the invention relates to an analytical method wherein a sample to be analysed is transferred by means of a pipette to a cartridge and this sample is applied to a sorbent contained in said cartridge and the sample, or at least an analyte present therein, is eluted from the sorbent using an eluent and the sample, or at least the analyte, is then subjected to an analysis.

49. 发明公开

EP1329705A2 Pipette- and cartridge-comprising set and related application methods 审中-公开
标题翻译： Eine Pipette和eine Kartusche umfassendes系统与zugehörigeAnwendungsverfahren
公开(公告)号：EP1329705A2
公开(公告)日：2003-07-23
申请号：EP03075168.9
申请日：2003-01-17
申请人： Spark Holland B.V.
发明人： Hilhorst, Martinus Josephus , Ooms, Jan Albert
IPC分类号： G01N1/40 , B01L3/02
CPC分类号： B01L9/54 , B01L3/0217 , G01N1/40 , G01N1/405 , G01N35/1079 , G01N2035/1053 , Y10T436/2575
摘要： The invention relates to a set comprising, on the one hand, a pipette (12) having a pipette orifice (11) and, on the other hand, a cartridge (1). The cartridge comprises: a housing (2); a chamber, containing sorbent (5), provided in the housing; an inlet (8) that connects the chamber to the outside of the housing and that has an inlet orifice (10) on the outside of the housing; an outlet that connects the chamber to the outside of the housing; an inlet closure (9) that is permeable to fluid and impermeable to the sorbent, which inlet closure extends over the entire inlet passage; an outlet closure (6), such as a mesh, that is permeable to fluid and impermeable to the sorbent, which outlet closure extends over the entire outlet passage; wherein the pipette orifice can be accommodated in the inlet orifice. The invention furthermore relates to a method for applying the sample to a sorbent by means of a pipette. In addition the invention relates to an analytical method wherein a sample to be analysed is transferred by means of a pipette to a cartridge and this sample is applied to a sorbent contained in said cartridge and the sample, or at least an analyte present therein, is eluted from the sorbent using an eluent and the sample, or at least the analyte, is then subjected to an analysis.
摘要翻译：一方面，本发明涉及一种组合物，其一方面包括具有移液管孔（11）的移液管（12），另一方面是一个药筒（1）。盒包括：壳体（2）; 一个设置在壳体中的容纳吸附剂（5）的腔室; 入口（8），其将所述腔室连接到所述壳体的外部，并且在所述壳体的外部具有入口孔口（10）; 将所述室连接到所述壳体的外部的出口; 入口封闭件（9），其可渗透流体并且不可渗透到吸附剂，该入口封闭件在整个入口通道上延伸; 出口封闭件（6），例如网状物，其可渗透流体并且不可渗透到吸附剂，该出口封闭件在整个出口通道上延伸; 其中移液管孔可容纳在入口孔中。本发明还涉及通过移液管将样品施加到吸附剂上的方法。此外，本发明涉及一种分析方法，其中待分析的样品通过移液管转移到药筒，并将该样品施用于包含在所述药筒和样品中的吸附剂，或至少存在于其中的分析物然后使用洗脱剂和样品或至少分析物从吸附剂洗脱，然后对其进行分析。

50. 发明授权

EP1092140B1 METHOD AND APPARATUS FOR EXTRACTING LIQUID SAMPLES FROM A CLOSED CONTAINER 有权
标题翻译：方法和装置去除液体样本密闭容器
公开(公告)号：EP1092140B1
公开(公告)日：2003-05-07
申请号：EP99927095.2
申请日：1999-05-27
申请人： DADE BEHRING INC.
发明人： DUNFEE, William, David , KAMINSKI, Edward, Stephen , MAZZA, John, Charles , MILLER, Kerry, Lynn , PARMER, Jeffery, Kenneth , ZUK, Paul, John
IPC分类号： G01N1/00
CPC分类号： G01N35/1079 , Y10T436/11 , Y10T436/2575
摘要： Extracting a quantity of liquid from a closed container by driving a cannula having a passage the length of the cannula and a groove a partial length of the cannula through the closure of the container until the groove establishes communication between a pressurized chamber and the container, thereby forcing liquid from the tube through the passage.

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