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    • 45. 发明授权
    • STERILIZED 5-AMINOLEVULINIC ACID
    • STERILISIERTE 5-AMINOLEVULINSÄURE
    • EP1007504B1
    • 2004-06-09
    • EP98944666.1
    • 1998-09-02
    • Dusa Pharmaceuticals, Inc.
    • GOLUB, Allyn
    • C07C229/22C07C227/42A61K51/04
    • C07C227/42C07C229/22
    • Colored 5-aminolevulinic acid crystals useful for photodynamic therapy are disclosed. Preferably the colored 5-aminolevulinic acid crystals have the color imparted by irradiation of the crystals, such as gamma radiation. The colored ALA crystals are preferably pharmaceutically pure and sterile and can be contained in a sealed sterile container. Also disclosed is sterile aqueous ALA solution which includes the colored ALA crystals contained in water. Also disclosed is a method for preparing colored ALA crystals which includes exposing non-irradiated ALA crystals to a radiation source at a dose sufficient to impart a color which is different than any color present in the non-irradiated crystals. Preferably the irradiation is sufficient to sterilize the ALA crystals. The sterile colored ALA crystals can be used in a kit for internal or external treatment and/or detection of a condition in a mammal, which includes the sterile, colored ALA crystals and sterile diluent, and in the case of internal treatment and/or detection optionally a catheter for administration of the ALA.
    • 46. 发明公开
    • FREQUENCY SELECTIVE TRANSIENT VOLTAGE PROTECTOR
    • 频率选择性瞬态电压保护器
    • EP1423897A2
    • 2004-06-02
    • EP02799931.7
    • 2002-12-12
    • Oneac Corporation
    • KNIGGE, Vincent, L.HAAKE, Paul, F.
    • H02H9/00
    • H02H9/04H04M3/18H04M3/2209H04M2207/203
    • A frequency selective transient voltage protector (FSTVP) circuit that may be used in connection with a communication line over which POTS and DSL service may be simultaneously provided. The FSTVP circuit attenuates high frequency transient voltages that exceed a predetermined voltage level, while permitting low frequency, generally high voltage signals (e.g., ring signals) and high frequency, low voltage signals (e.g., DSL signals) to pass with little or no attenuation. The FSTVP circuit comprises a frequency selective network (that comprises a frequency discriminator and a voltage discriminator) connected to an overvoltage protection device that shunts any high frequency transient voltages thus protecting devices connected downstream along the communications line from damage. The frequency selective network is tuned to gate the overvoltage protection device when the frequency and voltage of a signal present on the communication line exceed predetermined values.
    • 频率选择性瞬态电压保护器(FSTVP)电路,可以结合POTS和DSL服务可同时提供的通信线路使用。 FSTVP电路衰减超过预定电压电平的高频瞬态电压,同时允许低频通常高电压信号(例如环形信号)和高频低电压信号(例如,DSL信号)以很少或没有衰减通过 。 FSTVP电路包括连接到过压保护装置的频率选择性网络(其包括鉴频器和电压鉴别器),该过压保护装置分流任何高频瞬态电压,从而保护连接在通信线路下游的装置免受损坏。 当通信线上存在的信号的频率和电压超过预定值时,频率选择性网络被调谐以选通过电压保护装置。