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    • 24. 发明公开
    • MAGNETIC NANOPARTICLE, HAVING A CURIE TEMPERATURE WHICH IS WITHIN BIOCOMPATIBLE TEMPERATURE RANGE, AND METHOD FOR PREPARING SAME
    • 为具有居里温度内的生物相容性温度范围及其制造方法的磁性纳米粒子
    • EP2671570A4
    • 2015-05-27
    • EP12741665
    • 2012-01-31
    • UNIV KOREA RES & BUS FOUND
    • KIM YOUNG KEUNWU JUN HUAMIN JI HYUNLEE JI-SUNGJUNG JAE-HO
    • A61K9/16A61K47/02A61K47/48A61K49/08
    • G01N27/72A61K49/1827A61K49/1851A61K49/1866A61K49/1875C01G45/12C01P2002/72C01P2002/85C01P2004/04C01P2004/62C01P2004/64C01P2006/42G01N33/587
    • The present invention relates to a magnetic nanoparticle having a Curie temperature which is within a biocompatible temperature range, a method for preparing same, and a nanocomposite and a target substance detection composition comprising the magnetic nanoparticle. As the magnetic nanoparticle of the present invention has a Curie temperature within the temperature range of 0 degrees centigrade to 41 degrees centigrade, the ferromagnetic and paramagnetic properties of the magnetic nanoparticle may be controlled within a biocompatible temperature range at a temperature at which a biological control agent is not destroyed, and the temperature of the magnetic nanoparticle is adjusted to control the magnetic properties thereof such that the properties of the magnetic nanoparticle may be used only when ferromagnetic properties are required, such as in the case of signal amplification in detecting, separating, and delivering biological control agents. Accordingly, the magnetic nanoparticle of the present invention can minimize adverse effects of ferromagnetic properties thereof, and can be used in the effective detection and separation of biological control agents.
    • 本发明涉及一种具有一个居里温度所有这些是生物相容的温度范围内,其制备方法,以及纳米复合材料和目标物质的检测组合物,包含磁性纳米粒子的磁性纳米颗粒。 作为本发明的磁性纳米颗粒具有的温度范围为0摄氏度至41摄氏度范围内的居里温度时,磁性纳米颗粒的铁磁和顺磁性质可以生物相容性的温度范围内的温度下控制在哪一种生物控制 剂不被破坏,和磁性纳米颗粒的温度被调整,以控制磁特性及其检查没有磁性纳米粒子的性质可以仅当铁磁性质是必需的,:如在检测信号放大的情况下被使用,分离 ,并提供生物控制剂。 因此,本发明的磁性纳米粒子可以最小化铁磁性能的不利影响,以及它们的可生物控制剂的有效检测和分离中使用。