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21. 发明授权

EP2856968B1 DENTAL ULTRASONIC CLEANING DEVICE 失效转让
标题翻译：牙科超声波清洗装置
公开(公告)号：EP2856968B1
公开(公告)日：2018-01-31
申请号：EP13798018.1
申请日：2013-04-26
申请人： Showa University , GC Corporation , Honda Electronics Co., Ltd.
发明人： YAMAMOTO, Matsuo , TAKIGUCHI, Takashi , SATO, Masanori , INAGAKI, Katsuyuki , KUBOTA, Kazumasa , KOZAKA, Hideo , MIYAMOTO, Toshiaki
IPC分类号： A61C17/20 , A61C17/02
CPC分类号： A61C17/20 , A61C17/0202 , A61C17/0208
摘要： Provided is a dental ultrasonic cleaning device that efficiently cleans teeth or dentures in an oral cavity using ultrasonic waves. A dental ultrasonic cleaning device 1 emits ultrasonic waves through a cleaning-liquid (W1) to the surface of a cleaning-target 26, ultrasonically cleaning it. An ultrasonic horn 24 propagates ultrasonic waves being generated by an ultrasonic-wave transducer 23 and emits them from the vibratory surface 25 provided at the tip-end of the horn 24. A liquid-reserving part 27 is provided, surrounding the vibratory surface 25 of the ultrasonic horn 24, which temporarily reserves the cleaning-liquid (W1) between the vibratory surface 25 and the cleaning-target 26. A cap-member 33 is provided at a certain interval opposite the liquid-reserving part 27. A cleaning-liquid discharge-tube inlet 35 is connected to a vacuum tube 36 within the cap-member 33, allowing the cleaning-liquid W1 used during the ultrasonic cleaning to be vacuumed from the oral cavity, into the cap-member 33, and then discharged through the vacuum tube 36.

22. 发明授权

EP2735281B1 FLOW-TYPE ULTRASONIC ORAL CAVITY WASHING DEVICE 有权转让
标题翻译：流动型超声口腔清洗装置
公开(公告)号：EP2735281B1
公开(公告)日：2017-10-04
申请号：EP12814425.0
申请日：2012-07-11
申请人： Showa University , Honda Electronics Co., Ltd. , GC Corporation
发明人： YAMAMOTO, Matsuo , TAKIGUCHI, Takashi , SATO, Masanori , UEMURA, Kengo , HIKIDA, Tomomi , INAGAKI, Katsuyuki , KOZAKA, Hideo , MIYAMOTO, Toshiaki
IPC分类号： A61C17/02 , A61C1/07 , A61C17/20 , A61C1/08
CPC分类号： A61C17/20 , A61C1/0061 , A61C1/07 , A61C1/088 , A61C17/0202 , A61C17/0208

23. 发明公开

EP2735281A1 FLOW-TYPE ULTRASONIC ORAL CAVITY WASHING DEVICE AND FLOW-TYPE ULTRASONIC ORAL CAVITY WASHING METHOD 有权转让
标题翻译：超声波超声波超声波
公开(公告)号：EP2735281A1
公开(公告)日：2014-05-28
申请号：EP12814425.0
申请日：2012-07-11
申请人： Showa University , Honda Electronics Co., Ltd. , GC Corporation
发明人： YAMAMOTO, Matsuo , TAKIGUCHI, Takashi , SATO, Masanori , UEMURA, Kengo , HIKIDA, Tomomi , INAGAKI, Katsuyuki , KOZAKA, Hideo , MIYAMOTO, Toshiaki
IPC分类号： A61C17/20
CPC分类号： A61C17/20 , A61C1/0061 , A61C1/07 , A61C1/088 , A61C17/0202 , A61C17/0208
摘要： This invention is achieved to provide a water-flow ultrasonic oral-cavity cleaning device and a method for water-flow ultrasonic oral-cavity cleaning for surely and efficiently cleaning an oral cavity. In the water-flow ultrasonic oral-cavity cleaning device 1, cleaning liquid W1 from a cleaning-liquid supplying device 2 is supplied into a transducer case 21 through a supply port 26. Ultrasonic waves S1 are propagated into the cleaning liquid W1 from an ultrasonic transducer 22 mounted in a transducer mounting part 23 inside the transducer case 21. The water-flow of the cleaning liquid W1 is collected at the apical-part inside the transducer case 21, and then emitted from the issue 27 into the oral cavity, wherein power supply of 100W or less is supplied to the ultrasonic transducer 22 of 50mm or less in diameter to propagate the ultrasonic waves S1 of 100kHz or more to 3MHz or less in frequency into the cleaning liquid W1.
摘要翻译：本发明的目的是提供一种水流超声口腔清洁装置和用于确保和有效地清洁口腔的水流超声口腔清洁方法。在水流超声波口腔清洁装置1中，来自清洗液供给装置2的清洗液W1通过供给口26供给到换能器壳体21中。超声波S1从超声波传播到清洗液W1 换能器22安装在换能器壳体21内的换能器安装部23中。清洗液W1的水流被收集在换能器壳体21内的顶部，然后从问题27发射到口腔中，其中将100W以下的电源供给到直径为50mm以下的超声波换能器22，将频率为100kHz以上的超声波S1频率传播至3MHz以下，进入清洗液W1。

24. 发明公开

EP3939659A1 DRUG AND METHOD FOR TREATING OR PREVENTING COMPLICATIONS FROM DIABETES, USING SAID DRUG 无效转让
公开(公告)号：EP3939659A1
公开(公告)日：2022-01-19
申请号：EP20771088.0
申请日：2020-03-12
申请人： Showa University , TMS Co., Ltd.
发明人： SHIBATA, Keita , SHINOUCHI, Ryosuke , HASHIMOTO, Terumasa , NOBE, Koji
IPC分类号： A61P9/10 , A61P13/12 , A61P25/00 , A61P25/02 , A61P27/02 , A61K31/407 , A61K31/502
摘要： A drug containing a compound represented by formula (I) as an active ingredient, used for complications from diabetes.

25. 发明公开

EP3878400A1 INTRAORAL SENSING APPARATUS AND MANUFACTURING METHOD THEREOF 有权转让
公开(公告)号：EP3878400A1
公开(公告)日：2021-09-15
申请号：EP21161634.7
申请日：2021-03-09
申请人： Seiko Holdings Kabushiki Kaisha , Showa University
发明人： YOSHIDA, Yoshifumi , ISOGAI, Ryosuke , MAKI, Kotaro , SHIOTSU, Rumi
IPC分类号： A61C7/08 , A61B5/00 , A61C8/00 , A61C13/00
摘要： The present intraoral sensing apparatus is configured to be installed in an oral cavity, and is provided with: an electronic device equipped with electronic components mounted on a circuit board; a first dental resin material which completely covers the electronic device; a second dental resin material which completely covers the first dental resin material; and an intraoral instrument having a first recess in which the electronic device covered with the first dental resin material and the second dental resin material is accommodated.

26. 发明公开

EP3705892A1 DETECTION METHOD AND DETECTION DEVICE OF CIRCULATING TUMOR CELL 审中-公开
公开(公告)号：EP3705892A1
公开(公告)日：2020-09-09
申请号：EP20161512.7
申请日：2020-03-06
申请人： Showa University
发明人： NAOE, Michio , OGAWA, Yoshio , ISHII, Hikaru
IPC分类号： G01N33/543 , G01N33/574
摘要： A detection method of detecting CTCs as target cells contained in a test sample, the method includes a concentration step of concentrating the target cells contained in the test sample, a labeling step of labeling the target cells and other components by bringing the concentrated test sample into contact with first labeling antibodies in which antibodies specifically binding to antigens, which exclude antigens expressing in epithelial cells and specifically express in the target cells, are labeled by a first labeling substance, and into contact with second labeling antibodies in which antibodies binding to antigens expressing in the other components excluding the target cells are labeled by a second labeling substance, and a detection step of detecting, from the test sample, cells that are labeled by the first labeling antibodies and are not labeled by the second labeling antibodies as the target cells.

27. 发明授权

EP2340841B1 OSTEOGENESIS PROMOTER COMPRISING [4-(METHYLTHIO)PHENYLTHIO]METHANEBISPHOSPHONIC ACID OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AS ACTIVE INGREDIENT 有权转让
标题翻译： WITH [4-（甲硫基）苯硫基]METHANBISPHOSPHONSÄURE或药学上可接受的盐作为活性成分OSTEOGENESEPROMOTER THEREOF
公开(公告)号：EP2340841B1
公开(公告)日：2016-11-09
申请号：EP09811231.1
申请日：2009-08-05
申请人： Tohoku University , Showa University
发明人： SHINODA, Hisashi , IGARASHI, Kaoru , MURAKAMI, shinobu , SUZUKI, Keiko
IPC分类号： A61K31/663 , A61K9/08 , A61K47/02 , A61P1/02 , A61P19/08 , A61P43/00
CPC分类号： A61K31/663

28. 发明公开

EP2479738A1 EXERCISE MODEL FOR SMALL INTESTINE ENDOSCOPE 审中-公开
标题翻译： TRAININGSMODELLFÜREIN KLEINES DARMENDOSKOP
公开(公告)号：EP2479738A1
公开(公告)日：2012-07-25
申请号：EP10813585.6
申请日：2010-07-27
申请人： Showa University , Koken Co., Ltd.
发明人： ENDO, Yutaka , UNO, Hiroshi
IPC分类号： G09B23/28 , A61B1/00
CPC分类号： G09B23/285 , A61B1/00057
摘要： It is possible to provide a small intestine endoscope training simulator (11) which allows to obtain a feeling similar to that of inserting an endoscope (38) into the small intestine (34) of the living body (30) and learn the actual operation of the endoscope (38). This training simulator (11) includes a plurality of longitudinal elastic members (32) for applying an elastic force to each of a plurality of portions of a simulated small intestine (13). One end portion sides of the plurality of longitudinal elastic members (32) are respectively attached to the first attachment portions (27) on the simulated small intestine (13) side. The other end portion sides of the plurality of longitudinal elastic members (32) are respectively attached to the second attachment portions (33, 57) on the case (12) side.
摘要翻译：可以提供一种小肠内窥镜训练模拟器（11），其能够获得与将内窥镜（38）插入到生物体（30）的小肠（34）中的感觉相似的感觉，并且学习实际操作内窥镜（38）。该训练模拟器（11）包括多个用于向模拟小肠（13）的多个部分中的每一个施加弹性力的纵向弹性构件（32）。多个纵向弹性构件（32）的一个端部侧分别安装在模拟的小肠（13）侧上的第一附接部分（27）上。多个纵向弹性构件（32）的另一个端部侧分别安装在壳体（12）侧上的第二安装部分（33,57）上。

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