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1. 发明公开

EP3777645A1 ENDOSCOPE OBSERVATION ASSISTANCE DEVICE, ENDOSCOPE OBSERVATION ASSISTANCE METHOD, AND PROGRAM 审中-实审
公开(公告)号：EP3777645A1
公开(公告)日：2021-02-17
申请号：EP19785266.8
申请日：2019-04-12
申请人： Showa University , National University Corporation Tokai National Higher Education and Research System
发明人： MORI, Yuichi , KUDO, Shin-ei , MISAWA, Masashi , MORI, Kensaku
IPC分类号： A61B1/045 , G02B23/24
摘要： To provide an endoscope observation assistance apparatus and the like capable of improving a performance of endoscopic observation assistance so as to realize the observation of lesions by a doctor more easily and accurately.
An endoscope observation assistance apparatus (100) includes an image information acquiring part (31) to acquire and display a captured image of a luminal organ captured by the endoscope device (40) on a display (22), a lesion information acquisition part (32) to detect a predetermined lesion based on the captured image and to acquire lesion information regarding the lesion, a lesion disappearance determination part (34) to track the lesion based on the captured image and the lesion information and to determine whether or not the lesion has disappeared from the captured image, and a notification part (35) to notify a determination result when the lesion disappearance determination part (32) determines that the lesion has disappeared from the captured image. Alternatively, the notification part (35) may notify a lesion detection when a short time period passes after the lesion detection by the lesion information acquisition part (32).

2. 发明公开

EP3598935A1 BIOMETRIC INFORMATION DETECTION DEVICE AND METHOD OF PRODUCING THE SAME, BIOMETRIC INFORMATION DETECTION MODULE AND METHOD OF PRODUCING THE SAME 有权转让
公开(公告)号：EP3598935A1
公开(公告)日：2020-01-29
申请号：EP19169159.1
申请日：2019-04-15
申请人： Seiko Instruments Inc. , Showa University
发明人： WATANABE, Shunji , YOSHIDA, Yoshifumi , MAKI, Kotaro
IPC分类号： A61B5/00 , A61B5/1455 , A61B5/021 , A61B5/024
摘要： A biometric information detection device according to one embodiment of the present disclosure is configured to be installed in a living body, and includes a sensor, a battery, a mechanical switch, a sealing member, and a holding member. The mechanical switch switches between a conduction state in which power is supplied from the battery to the sensor and a cutoff state in which supply of the power is blocked. The sealing member seals all of the sensor, the battery, and the mechanical switch. The holding member is attached to the living body and holds the sealing member.

3. 发明公开

EP2898834A1 DEVICE FOR EVALUATING DIABETIC PERIPHERAL NEUROPATHY AND METHOD THEREFOR 有权
标题翻译： VORRICHTUNG ZUR BEURTEILUNG VON DIABETISCHER PERIPHERER NEUROPATHIE UND VERFAHRENDAFÜR
公开(公告)号：EP2898834A1
公开(公告)日：2015-07-29
申请号：EP12884846.2
申请日：2012-09-18
申请人： National Institute of Advanced Industrial Science and Technology , Showa University , Asuka Electric Co. Ltd. , Takahashi, Noriyo
发明人： INO, Shuichi , SATO, Mitsuru , TAKAHASHI, Noriyo , YOSHIMURA, Shinichi
IPC分类号： A61B10/00
CPC分类号： A61B5/4076 , A61B5/0051 , A61B5/4005 , A61B5/4029 , A61B5/4827 , A61B5/6829 , A61B5/742 , F04C2270/041
摘要： [Problem]
To provide an apparatus for measuring a sensory threshold at the time of application of a moving stimulus to a sole simply with high reproducibility and evaluating peripheral neuropathy originating in diabetes.
[Solution]
Provided are a foot pedestal 2, a probe 4 for applying a moving stimulus to a sole, and a probe driving structure 3, disposed on a base 1, for operating the probe 4 to separately move in directions intersecting at right angles along the sole. Also provided are an input switch 5 to be operated by a subject recognizing a moving stimulus, a drive controller 51 for controlling drive condition of the probe driving structure 3, and a main controller B for evaluating a measured sensory threshold. The main controller B preliminarily stores reference data of known sensory thresholds obtained by applying a moving stimulus to a sole of patients, and age correction factors calculated from standard values of sensory thresholds based on different ages of patients. The drive controller 51 controls drive condition of the probe driving structure 3 by using the reference data and the age correction factors to conduct a primary stimulus applying condition. Further, a secondary stimulus applying condition, and a tertiary stimulus applying condition are sequentially conducted to measure a sensory threshold.
摘要翻译： [问题]提供一种用于在将运动刺激应用于鞋底时简单地以高再现性测量感觉阈值并评估源于糖尿病的周围神经病变的装置。 [解决方案]设置有脚踏座2，用于向鞋底施加移动刺激的探针4和设置在基座1上的探针驱动结构3，用于操作探针4以沿直角相交的方向分开移动唯一的。还提供了由被识别移动刺激的被摄体操作的输入开关5，用于控制探针驱动结构3的驱动条件的驱动控制器51和用于评估测量的感觉阈值的主控制器B. 主控制器B预先存储通过将运动刺激应用于患者唯一而获得的已知感觉阈值的参考数据，以及基于患者不同年龄的感觉阈值的标准值计算的年龄校正因子。驱动控制器51通过使用参考数据和年龄校正因子来控制探针驱动结构3的驱动条件以进行主刺激施加条件。此外，依次进行二次刺激施加条件和三次刺激施加条件以测量感觉阈值。

4. 发明授权

EP2452679B1 TRIPRENYLPHENOLIC CYTOPROTECTIVE AGENT 有权转让
标题翻译：三苯乙酮ZELLSCHUTZMITTEL
公开(公告)号：EP2452679B1
公开(公告)日：2014-05-28
申请号：EP10796931.3
申请日：2010-02-05
申请人： National University Corporation Tokyo University Of Agriculture and Technology , Showa University , TMS Co., Ltd.
发明人： HONDA, Kazuo , HASHIMOTO, Terumasa , SHIBATA, Keita , HASEGAWA, Keiko , HASUMI, Keiji
IPC分类号： A61K31/407 , A61P7/02 , A61P9/10
CPC分类号： A61K31/407 , C07D491/04

5. 发明公开

EP2700378A1 DEVICE FOR WASHING ORAL CAVITY AND METHOD FOR WASHING ORAL CAVITY 审中-公开
标题翻译：设备清洗口腔和方法清洗嘴
公开(公告)号：EP2700378A1
公开(公告)日：2014-02-26
申请号：EP12774829.1
申请日：2012-04-18
申请人： Tohoku University , Showa University
发明人： SOYAMA, Hitoshi , YAMAMOTO, Matsuo , TAKIGUCHI, Takashi
IPC分类号： A61C17/02
CPC分类号： A61C17/0211 , A61C17/02 , A61C17/0208 , F04C2270/041
摘要： Provided is a device for cleaning oral cavity and a method for cleaning oral cavity capable of well cleaning stains such as plaque, tartar, and the like even in a narrow portion such as a clearance between teeth, a clearance between implants, and the like. A cover 11 includes a jetting orifice 11a and a discharge orifice 11b and covers a tooth 1 by leaving a clearance between the tooth 1 and the cover 11 so that the clearance can hold water. A jetting unit 12 is mounted in the jetting orifice 11a and includes a flow path 24a communicating with the clearance between the tooth 1 and the cover 11. The jetting unit 12 is configured to generate cavitation bubbles by water flowing toward the clearance in the flow path 24a and jets the cavitation bubbles toward the inside of the cover 11. The flow path 24a includes a small diameter part 24b having a flow path diameter smaller than that on the upstream side and an enlarged part 24c having a flow path diameter larger than that of the small diameter part 24b. A discharge unit 13 discharges water in the clearance between the tooth 1 and the cover 11 from the discharge orifice 11b.
摘要翻译：提供了一种用于清洁口腔和用于清洁能够良好清洁污渍口腔的方法的装置：诸如牙斑，牙垢，并且即使在狭窄部等：如植入物之间的间隙的状齿之间的间隙，和。盖11包括一个喷射孔11a和排出孔11b和通过使所述齿1和盖11，从而DASS模具间隙可以容纳水之间的间隙覆盖的齿1。喷射单元12被安装在喷射孔11a和具有流道24a与齿1和盖11。喷射单元12之间的间隙连通被配置成通过朝向所述流路的间隙流动的水，以产生空化气泡 24a和射流空化气泡朝向盖11的流路24a包括一个小直径部24b具有在上游侧和放大部24c具有流路直径比大的流路直径小于内小直径部分24b上。的放电单元13中的齿1并从所述排出孔11b中的盖11之间的间隙排出的水。

6. 发明公开

EP4398414A1 LIVING-BODY MONITORING DEVICE 审中-公开
公开(公告)号：EP4398414A1
公开(公告)日：2024-07-10
申请号：EP22864375.5
申请日：2022-08-24
申请人： Seiko Group Corporation , Showa University
发明人： ISOGAI Ryosuke , YOSHIDA Yoshifumi , MAKI Koutaro
IPC分类号： H01Q1/24 , A61B5/11 , A61C7/00 , A61C8/00 , A61C13/00 , A61C19/04 , H01Q9/30 , H01Q23/00
CPC分类号： A61B5/11 , A61C7/00 , A61C8/00 , A61C13/00 , A61C19/04 , H01Q1/24 , H01Q9/30 , H01Q23/00
摘要： A living-body monitoring device includes an electronic device including a circuit board and a living-body wearing instrument fixing or sealing the electronic device. A control unit, a battery, and an antenna are mounted on the circuit board. The circuit board has a length in a longitudinal direction and a length in a transverse direction and includes one or more copper-foil pattern layers. The antenna is disposed at one end in the longitudinal direction of the circuit board.

7. 发明公开

EP3998015A1 IMAGE ANALYZING DEVICE AND IMAGE ANALYZING METHOD 审中-实审
公开(公告)号：EP3998015A1
公开(公告)日：2022-05-18
申请号：EP19937090.9
申请日：2019-07-10
申请人： Cybernet Systems Co., Ltd. , Showa University
发明人： MISAWA, Masashi , MORI, Yuichi , KUDO, Shin-ei , WAKISAKA, Takashi , KAHARA, Hideo
IPC分类号： A61B1/045
摘要： This disclosure has an object to allow an automatic discrimination between a super enlarged image and a non-enlarged image in a computer diagnosis assistance system that analyzes a state of an epithelium using an image analysis. An image analyzing device (10) according to this disclosure is the image analyzing device (10) to be connected to an endoscope (20), and includes a target image determination unit (111) that obtains an image from the endoscope (20) and determines whether or not the image is a target image using a halation region included in the image, and an image analyzing unit (112) that analyzes a state of an epithelium, captured by the endoscope (20), using the target image when the image is the target image.

8. 发明公开

EP3689870A1 ANALGESIC DRUG USING PAC1 RECEPTOR ANTAGONISTIC DRUG 有权
公开(公告)号：EP3689870A1
公开(公告)日：2020-08-05
申请号：EP18862130.4
申请日：2018-09-27
申请人： Kagoshima University , Showa University
发明人： KURIHARA Takashi , TAKASAKI Ichiro , TOYOOKA Naoki , GOUDA Hiroaki
IPC分类号： C07D471/04 , A61K31/4178 , A61K31/519 , A61P25/04 , A61P25/06 , A61P29/02 , A61P43/00
摘要： This invention relates to an analgesic drug comprising a compound represented by the following formula (I) or (II),

wherein R 1 is a C 1-6 -alkoxy group or a C 1-6 -haloalkoxy group; R 2 is a hydrogen atom; and R is an indazolyl group substituted with a halogen atom; a substituted or unsubstituted phenyl group; a pyrazolyl group; or a substituted or unsubstituted aralkyl group;
or a salt thereof, or a solvate thereof.

9. 发明授权

EP2815777B1 WATER JET SPRAY NOZZLE, WATER JET SPRAY DEVICE, GASTROINTESTINAL TRACT CLEANING DEVICE, AND GASTRIC WALL CLEANING DEVICE 有权
标题翻译： WASSERSTRAHLSPRÜHDÜSE，WASSERSTRAHLSPRÜHVORRICHTUNG，REINIGUNGSVORRICHTUNGFÜRMAGEN-DARM-TRAKT UND MAGENWANDREINIGUNGSVORRICHTUNG
公开(公告)号：EP2815777B1
公开(公告)日：2017-01-18
申请号：EP13749702.0
申请日：2013-02-14
申请人： Tohoku University , Showa University
发明人： SOYAMA, Hitoshi , AMI, Katsunori , YAMAMOTO, Matsuo
IPC分类号： A61M3/00 , A61C17/02 , A61C17/00 , A61B1/12 , A61M3/02
CPC分类号： A61M3/0279 , A61B1/126 , A61C17/02 , A61M3/0216 , A61M3/0233 , A61M3/0258 , A61M2210/1053

10. 发明公开

EP2856968A1 DENTAL ULTRASONIC CLEANING DEVICE AND METHOD FOR CLEANING TEETH OR DENTURE USING ULTRASOUND 失效转让
标题翻译：牙齿清洁超声装置和方法用于清洁牙齿和义齿使用超声
公开(公告)号：EP2856968A1
公开(公告)日：2015-04-08
申请号：EP13798018.1
申请日：2013-04-26
申请人： Showa University , GC Corporation , Honda Electronics Co., Ltd.
发明人： YAMAMOTO, Matsuo , TAKIGUCHI, Takashi , SATO, Masanori , INAGAKI, Katsuyuki , KUBOTA, Kazumasa , KOZAKA, Hideo , MIYAMOTO, Toshiaki
IPC分类号： A61C17/20
CPC分类号： A61C17/20 , A61C17/0202 , A61C17/0208
摘要： Provided is a dental ultrasonic cleaning device that efficiently cleans teeth or dentures in an oral cavity using ultrasonic waves. A dental ultrasonic cleaning device 1 emits ultrasonic waves through a cleaning-liquid (W1) to the surface of a cleaning-target 26, ultrasonically cleaning it. An ultrasonic horn 24 propagates ultrasonic waves being generated by an ultrasonic-wave transducer 23 and emits them from the vibratory surface 25 provided at the tip-end of the horn 24. A liquid-reserving part 27 is provided, surrounding the vibratory surface 25 of the ultrasonic horn 24, which temporarily reserves the cleaning-liquid (W1) between the vibratory surface 25 and the cleaning-target 26. A cap-member 33 is provided at a certain interval opposite the liquid-reserving part 27. A cleaning-liquid discharge-tube inlet 35 is connected to a vacuum tube 36 within the cap-member 33, allowing the cleaning-liquid W1 used during the ultrasonic cleaning to be vacuumed from the oral cavity, into the cap-member 33, and then discharged through the vacuum tube 36.
摘要翻译：使用超声波在口腔提供了一种牙科用超声波清洗装置也有效地清除牙齿或假牙英寸的牙科用超声波清洗装置1通过清洗液（W1）向清洗对象26的表面发射超声波，超声波清洗它。超声变幅杆24传播通过在超声波波换能器23所产生的超声波，并从在喇叭24.一种液体贮留部27的前端设置在振动面25可发出他们被提供，周围的振动表面25 超声波喇叭24，其暂时保留振动面25和清洗对象26.一种帽构件33之间的清洗液（W1）在所述液体贮留部27，一种清洗液相对的一定的间隔设置排出管入口35连接到盖构件33内的真空管36，从而使超声波清洗过程中使用的清洗液W1从口腔被抽真空，在所述盖部件33，再通过排出真空管36

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