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    • 135. 发明授权
    • Diabetes therapy device enabling shifting of parameter profiles
    • 糖尿病治疗仪,其允许的参数曲线的位移
    • EP2306352B1
    • 2013-01-09
    • EP10009697.3
    • 2010-09-16
    • Roche Diagnostics GmbHF.Hoffmann-La Roche AG
    • Prod'hom, GillesPrudhomme, ThierryHellwig, RobertTeupe, Dr. med. Bernhard
    • G06F19/00
    • A61M5/14244A61M5/1723A61M2005/14208A61M2205/50A61M2205/52G06F19/00G06F19/3468
    • 1. Diabetes therapy device, comprising: a) a profile memory, the profile memory being configured to store a parameter profile, the parameter profile defining at least one parameter that is associated with insulin administration as a function of time for a generally circadian chronobiological cycle, and to further store a dedicated reference time mark, the reference time mark indicating the beginning of a cycle; b) an electronic controller unit, the controller unit being coupled to the profile memory to determine, based on the at least one parameter, insulin amounts to be administered as a function of the running time in accordance with a current matching of the parameter profile and the running time, the controller unit being further configured to modify the matching of the parameter profile and the running time, the modification comprising the steps of €¢ receiving trigger information that is indicative for an upcoming cycle trigger event occurring at an upcoming trigger time, the cycle trigger event being a defined event that generally occurs once per day and triggers the beginning of a cycle, €¢ computing a modified matching in dependence of the reference time mark and the trigger time, the modified matching being time-shifted as compared to the current matching, €¢ applying the modified matching by making the modified matching the current matching, such that future insulin amounts to be administered are determined in accordance with the modified matching. The diabetes therapy device may especially be or comprise an insulin pump and the parameter may be or comprise a basal infusion rate. The device is favorable with respect to therapy-quality by considering the non-constant duration of physiological cycles, resulting from sporadic exceptional events and/or a generally flexible lifestyle.
    • 138. 发明公开
    • MONITORING DEVICE FOR MANGEMENT OF INSULIN DELIVERY
    • ÜBERWACHUNGSVORRICHTUNGZUR VERWALTUNG EINER INSULINABGABE
    • EP2483824A1
    • 2012-08-08
    • EP10763452.9
    • 2010-08-24
    • MOR RESEARCH APPLICATIONS LTD.
    • ATLAS, EranNIMRI, RevitalMILLER, ShaharGRUNBERG, Eli AviramPHILLIP, Moshe
    • G06F19/00
    • G06F19/3468A61B5/14532A61M5/1723A61M2005/14208A61M2230/201G06F19/00G06N7/00G16H50/20
    • Monitoring system and method for use with diabetic treatment management. The system includes: a communication interface configured to permit access to stored raw log data, obtained over a certain time, being indicative of glucose measurements, meals consumed and insulin delivery; and a control unit including an unsupervised learning controller configured to receive and process said raw log data and determine at least one global insulin pump setting of basal rate, correction factor, carbohydrate ratio and insulin activity curve parameters. The system may include a processing unit including a first processor for processing measured data indicative of blood glucose level and generating first processed data, a second processor including at least one fuzzy logic module which receives input parameters corresponding to the measured data, the first processed data and a reference data, and processes the data to produce a qualitative output parameter to determine whether any treatment parameter should be modified.
    • 用于糖尿病治疗管理的监测系统和方法。 该系统包括:通信接口,被配置为允许访问在一定时间内获得的存储的原始日志数据,其指示葡萄糖测量值,膳食消耗量和胰岛素递送; 以及控制单元,其包括无监督学习控制器,其被配置为接收和处理所述原始对数数据并且确定基础速率,校正因子,碳水化合物比率和胰岛素活性曲线参数的至少一个全局胰岛素泵设置。 该系统可以包括处理单元,该处理单元包括第一处理器,用于处理指示血糖值的测量数据并产生第一处理数据;第二处理器,包括至少一个模糊逻辑模块,其接收对应于测量数据的输入参数,第一处理数据 和参考数据,并处理数据以产生定性输出参数,以确定是否应修改任何治疗参数。