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101. 发明授权

EP1424397B1 Method for producing L-glutamine and L-glutamine producing bacterium 有权转让
标题翻译：用于生产L-谷氨酰胺和L-谷氨酰胺生产菌的方法
公开(公告)号：EP1424397B1
公开(公告)日：2011-01-19
申请号：EP03026890.8
申请日：2003-11-24
申请人： Ajinomoto Co., Inc.
发明人： Nakamura, Jun , Akiyama, Kayo
IPC分类号： C12P13/14 , C12N9/00 , C12N9/80 , C12N15/52
CPC分类号： C12P13/14 , C12N9/80

102. 发明公开

EP2267007A1 Neue, Polyaminosäuren bildende oder abbauende Genprodukte von Bacillus licheniformis und darauf aufbauende verbesserte biotechnologische Produktionsverfahren 有权转让
标题翻译：新建，聚地衣芽孢杆菌的创意或有辱人格的基因，并建立在提高生物技术生产
公开(公告)号：EP2267007A1
公开(公告)日：2010-12-29
申请号：EP10175015.6
申请日：2005-06-11
申请人： Henkel AG & Co. KGaA
发明人： Feesche, Jörg , Bessler, Cornelius , Evers, Stefan , Maurer, Karl-Heinz , Ehrenreich, Armin , Veith, Birgit , Liesegang, Heiko , Henne, Anke , Herzberg, Christina , Gottschalk, Gerhard
IPC分类号： C07K14/32 , C12P13/14 , C12R1/10 , C12N5/10
CPC分类号： C07K14/32 , C12N15/52 , C12P13/04
摘要： Die Bildung von Polyaminosäuren, insbesondere von Poly-gamma-Glutamat, bei der Fermentation von Mikroorganismen soll verringert werden und es sollen Gene identifiziert werden, die für Proteine codieren, die an der Bildung von derartigen Verbindungen beteiligt sind. Dies gelingt durch das Gen ywtA und dessen Genprodukt von Bacillus licheniformis und hinreichend ähnliche Gene und Proteine, die in vivo an der Bildung von Polyaminosäuren beteiligt sind. Sie können zur Verbesserung biotechnologischer Produktionsverfahren durch Mikroorganismen genutzt werden, indem sie funktionell inaktiviert werden.
摘要翻译：的聚氨基酸的形成，特别是多聚-γ-谷氨酸的，在微生物的发酵是被缩小和它将被识别编码中涉及的这种化合物的形成的蛋白质的基因。这是由基因ywtA并且其在聚氨基酸的形成涉及在体内地衣芽孢杆菌和足够类似的基因和蛋白质的基因来实现的。它们可用于改善微生物生物技术生产，通过被功能失活。

103. 发明公开

EP2248906A1 METHOD OF PRODUCING L-AMINO ACID 审中-公开
标题翻译：生产L-氨基酸的方法
公开(公告)号：EP2248906A1
公开(公告)日：2010-11-10
申请号：EP09704195.8
申请日：2009-01-23
申请人： Ajinomoto Co., Inc.
发明人： SUZUKI, Shigeo , USUDA, Yoshihiro , HASHIRO, Shuhei
IPC分类号： C12P13/04 , C12N15/09 , C12P13/08 , C12P13/14
CPC分类号： C12P13/04 , C12P13/08 , C12P13/14
摘要： An L-amino acid is produced by culturing a bacterium having an L-amino acid-producing ability in a medium containing a processed product of a microalga which promotes production and accumulation of the L-amino acid by the bacterium, such as a disruption product of the culture of the microalga, an extract or a fractionation product of the disruption product, containing a mixture of organic substances produced by the microalga, or a hydrolysate of the disruption product, the extract or the fractionation product, especially a saccarification product of starches or a hydrolysate of fats and oils as the processed product, to produce and accumulate the L-amino acid in culture, and collecting the L-amino acid from the culture.
摘要翻译：通过在含有微藻加工产物的培养基中培养具有L-氨基酸生产能力的细菌，所述微藻加工产物促进细菌产生和积累L-氨基酸，例如破坏产物微藻的培养物，破碎产物的提取物或分级分离产物，其含有由微藻产生的有机物质的混合物或破碎产物，提取物或分级产物的水解产物，特别是淀粉的糖化产物或作为加工产品的脂肪和油的水解产物，以在培养物中产生并积累L-氨基酸，并从培养物中收集L-氨基酸。

104. 发明公开

EP2084262A4 A MICROORGANISM PRODUCING GLUTAMIC ACID IN HIGH YIELD AND A PROCESS OF PRODUCING GLUTAMIC ACID USING THE SAME 有权
标题翻译：谷氨酸高产的微生物和方法谷氨酸的生产，使
公开(公告)号：EP2084262A4
公开(公告)日：2010-02-17
申请号：EP07833281
申请日：2007-10-11
申请人： CJ CHEILJEDANG CORP
发明人： JIN CHANG HYUN , OH KI-HOON , CHO KWANG MYUNG , PARK YOUNG HOON
IPC分类号： C12N1/21 , C12P1/04 , C12P13/14
CPC分类号： C12P13/14 , C12N15/01

105. 发明公开

EP2116595A1 AN L-AMINO ACID-PRODUCING MICROORGANISM AND A METHOD FOR PRODUCING AN L-AMINO ACID 有权
标题翻译：微生物生产L-氨基酸和方法用于生产L-氨基酸
公开(公告)号：EP2116595A1
公开(公告)日：2009-11-11
申请号：EP08703110.0
申请日：2008-01-11
申请人： Ajinomoto Co., Inc.
发明人： TAKIKAWA, Rie , HARA, Yoshihiko
IPC分类号： C12N1/21 , C12N15/09 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/22 , C12P13/24
CPC分类号： C12P13/06 , C07K14/24 , C07K14/245 , C12N9/14 , C12N15/52 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/22 , C12P13/24
摘要： A microorganism belonging to the family Enterobacteriaceae , which has an L-amino acid-producing ability and has been modified so that the kdp system is enhanced, is cultured in a medium to produce and accumulate an L-amino acid in the medium or cells of the microorganism, and the L-amino acid is collected from the medium or cells to produce the L-amino acid.
摘要翻译：属于肠杆菌科，其具有L-氨基酸生产能力且经过修饰所以做了KDP系统被增强，A微生物在培养基中培养以产生和在培养基或细胞中积累L-氨基酸微生物，和L-氨基酸，从培养基或细胞中收集，以产生L-氨基酸。

106. 发明公开

EP1978094A4 METHOD FOR PRODUCTION OF L-GLUTAMINE 有权转让
标题翻译：工艺生产L-谷氨酰胺
公开(公告)号：EP1978094A4
公开(公告)日：2009-06-24
申请号：EP06843405
申请日：2006-12-27
申请人： KYOWA HAKKO BIO CO LTD
发明人： HAYASHI MIKIRO , MAEDA MASAKI , YONETANI YOSHIYUKI
IPC分类号： C12N15/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N15/09 , C12P13/14
CPC分类号： C12N9/93 , C12P13/14
摘要： Disclosed are: a polypeptide which is characterized in that the polypeptide comprises an amino acid sequence having the deletion, substitution or addition of at least one amino acid residue in the amino acid sequence for glutamine synthetase 2 derived from a microorganism belonging to the genus Corynebacterium, and that a Corynebacterium capable of producing the polypeptide can produce L-glutamine; DNA encoding the polypeptide; recombinant DNA carrying the DNA; a microorganism harboring the DNA or the recombinant DNA; and a method for production of L-glutamine using the microorganism.

107. 发明授权

EP1577396B1 Method for producing L-amino acids by fermentation using bacteria having enhanced expression of xylose utilization genes 有权
标题翻译：一种用于使用与木糖的基因的表达增加的细菌的发酵来生产L-氨基酸的过程
公开(公告)号：EP1577396B1
公开(公告)日：2009-06-10
申请号：EP05005784.3
申请日：2005-03-16
申请人： Ajinomoto Co., Inc.
发明人： Marchenko, Aleksey Nikolaevich , Benevolensky, Sergey Vladimirovich , Klyachko, Elena Vitalievna , Kozlov, Yuri Ivanovich , Voroshilova, Elvira Borisovna , Gusyatiner, Mikhail Markovich
IPC分类号： C12P13/04 , C12P13/08 , C12P13/14 , C12P13/22 , C12P13/24 , C12N1/20
CPC分类号： C12N15/52 , C12P13/04 , C12P13/08 , C12P13/14 , C12P13/227 , C12P13/24

108. 发明公开

EP2062975A1 METHOD FOR PRODUCTION OF L-GLUTAMIC ACID 有权转让
标题翻译：生产L-谷氨酸的方法
公开(公告)号：EP2062975A1
公开(公告)日：2009-05-27
申请号：EP07806387.2
申请日：2007-08-30
申请人： Kyowa Hakko Bio Co., Ltd.
发明人： ADACHI, Yugo , HAYASHI, Mikiro , SENOO, Akihiro , YONETANI, Yoshiyuki , HASHIMOTO, Shin-ichi
IPC分类号： C12N15/09 , C12N1/21 , C12P13/14
CPC分类号： C12N9/1205 , C12N9/0008 , C12P13/14
摘要： According to the present invention, it is possible to provide a microorganism belonging to the genus Corynebacterium , wherein the activity of (1) a protein having the amino acid sequence shown by any one of SEQ ID NO:1 to 3, or (2) a protein having a homology of 80% or more to the amino acid sequence shown by any one of SEQ ID NO:1 to 3, and having substantially the same activity as the activity of a protein having the amino acid sequence shown by any one of SEQ ID NO:1 to 3, has been reduced or lost, and wherein the activity of (3) a protein having the amino acid sequence shown by SEQ ID NO:4, or (4) a protein having a homology of 80% or more to the amino acid sequence shown by SEQ ID NO:4, and having substantially the same activity as the activity of a protein having the amino acid sequence shown by SEQ ID NO:4, has been reduced or lost, and a process for producing L-glutamine using the microorganism and the like.
摘要翻译：根据本发明，可以提供属于棒状杆菌属的微生物，其中（1）具有SEQ ID NO：1-3中任一项所示氨基酸序列的蛋白或（2）具有SEQ ID NO：与序列号1〜3中任一项所示的氨基酸序列具有80％以上的同源性的蛋白质，其具有与具有下述任一氨基酸序列的蛋白质的活性大致相同的活性，（3）具有序列号4所示的氨基酸序列的蛋白质或（4）具有80％同源性的蛋白质的活性的蛋白质的活性降低或丧失，与SEQ ID NO：4所示的氨基酸序列相比，具有与具有SEQ ID NO：4所示的氨基酸序列的蛋白质的活性基本相同的活性已被减少或丧失，并且生产方法使用微生物的L-谷氨酰胺等。

109. 发明公开

EP2054500A2 AN L-GLUTAMIC ACID PRODUCING BACTERIUM AND A METHOD FOR PRODUCING L-GLUTAMIC ACID 有权
标题翻译： L-谷氨酸生产菌和用于生产L-谷氨酸
公开(公告)号：EP2054500A2
公开(公告)日：2009-05-06
申请号：EP07805986.2
申请日：2007-08-16
申请人： Ajinomoto Co., Inc.
发明人： HARA, Yoshihiko , IZUI, Hiroshi
IPC分类号： C12N1/00 , C12N1/21 , C12N15/09 , C12P13/14 , C12R1/18 , C12R1/22
CPC分类号： C12P13/14 , C07K14/24 , C07K14/26 , C07K14/265 , C07K14/27
摘要： An L-glutamic acid producing bacterium which belongs to the genus Pantoea, Enterobacter, Klebsiella or Erwinia, wherein the bacterium has been modified by gene recombination to inactivate the rpoS gene, is cultured in a medium to cause accumulation of L-glutamic acid in the medium, and L-glutamic acid is collected from the medium.

110. 发明公开

EP2042043A1 A shelf-stable taste enhancing cultured savoury base and a process for its preparation 审中-公开
标题翻译： Haltbare，geschmacksverstärkende，kultivierte，wohlschmeckende Base und Herstellungsverfahrendafür
公开(公告)号：EP2042043A1
公开(公告)日：2009-04-01
申请号：EP07117260.5
申请日：2007-09-26
申请人： Nestec S.A.
发明人： Palzer, Stefan , Nikolic, David , Berends, Pieter , Ho Dac, Thang , Fleury Rey, Yvette , Ulmer, Helge
IPC分类号： A23L1/23 , A23L1/226 , C12P13/14 , C12P19/32
CPC分类号： C12P19/32 , A23L27/2028 , A23L27/21 , A23L27/24 , C12P13/14
摘要： The invention concerns a cultured savoury base with increased Umami power comprising:
- up to 80 % of naturally derived compounds taken in the group consisting of MSG,IMP and GMP,
- naturally food derived acids,
said base having no bitterness.
摘要翻译：本发明涉及具有增加的Umami功率的培养的咸味基质，其包含： - 高达80％的天然衍生化合物，其选自MSG，IMP和GMP， - 天然食物衍生的酸，所述碱不具有苦味。

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