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    • 5. 发明公开
    • VALVE MANIFOLDS FOR SIMULATED MOVING BED CHROMATOGRAPHY
    • 用于模拟移动床色谱的阀门流路
    • EP3241021A1
    • 2017-11-08
    • EP15822943.5
    • 2015-12-23
    • GE Healthcare Bio-Sciences AB
    • GEBAUER, KlausOLOVSSON, Bjorn Markus
    • G01N30/20B01D15/18G01N30/88G01N30/42
    • B01D15/1842G01N30/20G01N30/42G01N30/88G01N2030/205G01N2030/8881
    • Go between a first portion of the central duct and an opposed second portion of the central duct, a first plurality of connectors, each connector of the first plurality of connectors for connecting to a distinct chromatographic separation column and/or feed or extraction tubing or to a connector of an adjacent manifold; a second plurality of connectors, each connector of the second plurality of connectors for connecting to a distinct chromatographic separation column and/or feed or extraction tubing or to a connector of an adjacent manifold; wherein said manifold body further defines: a first plurality of branch ducts, each branch duct of which extending from the first portion of the central duct to an individual one of the first plurality of connectors, each of the branch ducts of the first plurality of branch ducts comprising a closable branch valve providing selectable fluid communication between a respective connector and the first portion of the central duct, a second plurality of branch ducts, each branch duct of which extending from the second portion of the central duct to an individual one of the second plurality of connectors, each of the branch ducts of the second plurality of branch ducts comprising a closable branch valve providing selectable fluid communication between a respective connector and the second portion of the central duct; first and second ports in fluid communication with the centrally-located closable duct valve wherein said first port communicates with said first portion of the central duct and said second port communicates with said second portion of said central duct, wherein one of said first and second ports is further positioned to communicate with said central duct at a location between the centrally-located closable duct valve and the first and second plurality of branch ducts, respectively.
    • 6. 发明公开
    • METHOD AND VALVE IN CONTINUOUS CHROMATOGRAPHY SYSTEM
    • VERFAHREN通风系统ZUR KONTINUIERLICHEN CHROMATOGRAPHIE
    • EP3123164A1
    • 2017-02-01
    • EP15712294.6
    • 2015-03-16
    • GE Healthcare Bio-Sciences AB
    • OLOVSSON, Bjorn Markus
    • G01N30/20B01D15/18F16K11/074G01N30/44G01N30/80
    • G01N30/20B01D15/1842F16K11/0743G01N30/44G01N30/80G01N2030/202
    • A method and a rotary valve (65) in a continuous chromatography system. The rotary valve (65) comprises a stator (5) with an inner stator face (5a), and a rotor (12) with an inner rotor face (12a) arranged in sealing contact with the inner stator face (5a). The stator (5) comprises at least a first and a second inlet orifices (81,81), at least two first outlet (85a) orifices, a second outlet orifice (87) and a third outlet orifice (89), and the rotor interconnection paths are arranged to: - in at least one rotary position connect the first inlet orifice to the second outlet orifice and the second inlet orifice to the third outlet orifice, and - in at least two other rotary positions connect the first inlet orifice with any one of the first outlet orifices at the same time as the second inlet orifice is connected to the second outlet orifice.
    • 连续色谱系统中的方法和旋转阀(65)。 旋转阀(65)包括具有内定子面(5a)的定子(5)和具有与内定子面(5a)密封接触的内转子面(12a)的转子(12)。 定子(5)至少包括第一和第二入口孔口(81,81),至少两个第一出口孔口(85a),第二出口孔口(87)和第三出口孔口(89),转子 互连路径被布置成: - 在至少一个旋转位置中,将第一入口孔连接到第二出口孔,将第二入口孔连接到第三出口孔,并且 - 在至少两个其它旋转位置中,将第一入口孔与任何 与第二入口孔同时的第一出口孔中的一个连接到第二出口孔。