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1. 发明公开

EP1859820A2 Polymeric stent having modified molecular structures in the flexible connectors and in the radial struts and the radial arcs of the hoops 审中-公开
标题翻译：聚合物支架与所述柔性连接件改变的分子结构和所述轮胎的径向支撑和径向弧
公开(公告)号：EP1859820A2
公开(公告)日：2007-11-28
申请号：EP07252162.8
申请日：2007-05-25
申请人： Cordis Corporation
发明人： Burgermeister, Robert , Contiliano, Joseph H. , Dave, Vipul , Li, Yufu , Narayanan, Pallassana V. , Overaker, David W. , Zhang, Qiang
IPC分类号： A61L27/26 , A61L27/54 , A61L31/04 , A61L31/16
CPC分类号： A61L31/04 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2210/0004 , A61F2230/0013 , A61F2250/0018 , A61F2250/0028 , A61L27/26 , A61L27/54 , A61L31/14 , A61L31/16 , A61L2300/236 , A61L2300/41 , A61L2300/416 , A61L2300/418 , A61L2300/43
摘要： A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. By preferential mechanical deformation of the polymer, the polymer chains may be oriented to achieve certain desirable performance characteristics.
摘要翻译：生物相容性材料可以被配置成任何数量包括管腔内的支架植入医疗装置。聚合材料可以被用于制造任何合成设备，包括支架。支架可以是球囊扩张或自扩张。通过聚合物的优惠机械变形时，聚合物链可被定向为获得某些所需的性能特性。

2. 发明公开

EP1837042A3 Implantable device formed from polymer blends having modified molecular structures 审中-公开
标题翻译：制成的聚合物 - 增塑剂掺合物的可植入装置具有修饰的分子结构
公开(公告)号：EP1837042A3
公开(公告)日：2007-10-24
申请号：EP07250632.2
申请日：2007-02-15
申请人： Cordis Corporation
发明人： Burgermeister, Robert , Dave, Vipul , Narayanan, Pallassana V. , Overaker, David W
IPC分类号： A61L31/04 , A61L31/16 , A61L27/26 , A61L27/54
CPC分类号： A61L31/041 , A61L31/16 , A61L31/18 , A61L2300/416 , A61L2300/42
摘要： A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. The polymeric materials may include additives such as drugs or other bioactive agents as well as radiopaque agents. By preferential mechanical deformation of the polymer, the polymer chains may be oriented to achieve certain desirable performance characteristics.
In one embodiment, an implantable medical device comprises a frame structure, the frame structure including at least one element having one or more sections being formed from at least two polymers, one of the at least two polymers having a substantially higher ultimate strain than the other of the at least two polymers blended to create a deformable frame structure having increased toughness, and wherein at least one of the one or more sections having an amount of alignment of the polymer chains of the blend in a direction of the at least one or more sections greater than an amount of alignment of the polymer chains of the blend in a direction of another of the at least one or more sections.

3. 发明公开

EP1867306A3 Polymeric stent having modified molecular structures in the flexible connections 审中-公开
标题翻译：聚合物支架具有改变的分子结构中的柔性连接
公开(公告)号：EP1867306A3
公开(公告)日：2008-04-09
申请号：EP07252129.7
申请日：2007-05-25
申请人： Cordis Corporation
发明人： Burgermeister, Robert , Contiliano, Joseph H. , Dave, Vipul , Li, Yufu , Narayanan, Pallassana V. , Overaker, David W. , Zhang, Qiang
IPC分类号： A61F2/90 , A61L31/04 , A61F2/00
CPC分类号： A61L31/148 , A61B2017/00871 , A61F2/91 , A61F2/915 , A61F2/94 , A61F2002/91533 , A61F2002/91541 , A61F2210/0004 , A61F2210/0014 , A61F2230/0013 , A61F2250/0018 , A61F2250/0028 , A61L29/085 , A61L29/16 , A61L31/04 , A61L31/10 , A61L31/14 , A61L31/16 , A61L2300/222 , A61L2300/236 , A61L2300/41 , A61L2300/416 , A61L2300/42
摘要： A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. By preferential mechanical deformation of the polymer, the polymer chains may be oriented to achieve certain desirable performance characteristics.

4. 发明公开

EP1867306A2 Polymeric stent having modified molecular structures in the flexible connections 审中-公开
标题翻译：聚合物支架在柔性连接中具有改进的分子结构
公开(公告)号：EP1867306A2
公开(公告)日：2007-12-19
申请号：EP07252129.7
申请日：2007-05-25
申请人： Cordis Corporation
发明人： Burgermeister, Robert , Contiliano, Joseph H. , Dave, Vipul , Li, Yufu , Narayanan, Pallassana V. , Overaker, David W. , Zhang, Qiang
IPC分类号： A61F2/90 , A61L31/04 , A61F2/00
CPC分类号： A61L31/148 , A61B2017/00871 , A61F2/91 , A61F2/915 , A61F2/94 , A61F2002/91533 , A61F2002/91541 , A61F2210/0004 , A61F2210/0014 , A61F2230/0013 , A61F2250/0018 , A61F2250/0028 , A61L29/085 , A61L29/16 , A61L31/04 , A61L31/10 , A61L31/14 , A61L31/16 , A61L2300/222 , A61L2300/236 , A61L2300/41 , A61L2300/416 , A61L2300/42
摘要： A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. By preferential mechanical deformation of the polymer, the polymer chains may be oriented to achieve certain desirable performance characteristics.
摘要翻译：生物相容性材料可以被配置成任何数量的可植入医疗装置，包括腔内支架。可以使用聚合物材料来制造这些装置中的任何装置，包括支架。支架可以是气囊可扩张的或自扩张的。通过聚合物的优先机械变形，聚合物链可以被定向以实现某些期望的性能特征。

5. 发明公开

EP1837042A2 Implantable device formed from polymer blends having modified molecular structures 审中-公开
标题翻译：由具有改性分子结构的聚合物共混物形成的可植入装置
公开(公告)号：EP1837042A2
公开(公告)日：2007-09-26
申请号：EP07250632.2
申请日：2007-02-15
申请人： Cordis Corporation
发明人： Burgermeister, Robert , Dave, Vipul , Narayanan, Pallassana V. , Overaker, David W
IPC分类号： A61L31/04 , A61L31/16 , A61L27/26 , A61L27/54
CPC分类号： A61L31/041 , A61L31/16 , A61L31/18 , A61L2300/416 , A61L2300/42
摘要： A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. The polymeric materials may include additives such as drugs or other bioactive agents as well as radiopaque agents. By preferential mechanical deformation of the polymer, the polymer chains may be oriented to achieve certain desirable performance characteristics.
In one embodiment, an implantable medical device comprises a frame structure, the frame structure including at least one element having one or more sections being formed from at least two polymers, one of the at least two polymers having a substantially higher ultimate strain than the other of the at least two polymers blended to create a deformable frame structure having increased toughness, and wherein at least one of the one or more sections having an amount of alignment of the polymer chains of the blend in a direction of the at least one or more sections greater than an amount of alignment of the polymer chains of the blend in a direction of another of the at least one or more sections.
摘要翻译：生物相容性材料可以被配置成任何数量的可植入医疗装置，包括腔内支架。可以使用聚合物材料来制造这些装置中的任何装置，包括支架。支架可以是气囊可扩张的或自扩张的。聚合物材料可以包括添加剂如药物或其他生物活性剂以及不透射线的试剂。通过聚合物的优先机械变形，聚合物链可以被定向以实现某些期望的性能特征。在一个实施例中，可植入医疗装置包括框架结构，框架结构包括至少一个元件，该元件具有由至少两种聚合物形成的一个或多个部分，至少两种聚合物中的一种具有比另一种更高的极限应变的所述至少两种聚合物共混以产生具有增加的韧性的可变形框架结构，并且其中所述一个或多个部分中的至少一个具有所述共混物的聚合物链在所述至少一个或多个其截面大于所述共混物的聚合物链在所述至少一个或多个部分中的另一个部分的方向上的排列量。

6. 发明授权

EP1504775B1 A coating for controlled release of a therapeutic agent 失效转让
标题翻译：层用于治疗剂的控制释放
公开(公告)号：EP1504775B1
公开(公告)日：2010-12-15
申请号：EP04254535.0
申请日：2004-07-29
申请人： Cordis Corporation
发明人： Borges, John , Carballo, Maritza , Narayanan, Pallassana V. , Shaw, William D., Jr. , Widenhouse, Christopher W.
IPC分类号： A61L31/16
CPC分类号： A61K9/0024 , A61K31/395 , A61L27/34 , A61L27/54 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/608 , A61L2420/08 , C08L33/10 , C08L27/16

8. 发明公开

EP1825870A2 Implantable device formed from polymer and plasticizer blends having modified molecular structures 审中-公开
标题翻译：由具有改性分子结构的聚合物和增塑剂共混物形成的可植入装置
公开(公告)号：EP1825870A2
公开(公告)日：2007-08-29
申请号：EP07250639.7
申请日：2007-02-15
申请人： Cordis Corporation
发明人： Burgermeister, Robert , Dave, Vipul , Narayanan, Pallassana V. , Overaker, David W
IPC分类号： A61L27/50 , A61L27/14 , A61L31/04 , A61L31/14
CPC分类号： A61L31/04 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91575 , A61F2220/0008 , A61F2220/0075 , A61F2230/0013 , A61L31/141 , A61L31/18 , B23K2203/42 , B23K2203/50
摘要： A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. The polymeric materials may include additives such as drugs or other bioactive agents as well as radiopaque agents. By preferential mechanical deformation of the polymer, the polymer chains may be oriented to achieve certain desirable performance characteristics.
In one embodiment, an implantable medical device comprises a frame structure, the frame structure including at least one element having one or more sections being formed from at least one polymer and at least one plasticizer blended to create a deformable frame structure having increased toughness, and wherein at least one of the one or more sections having an amount of alignment of the polymer chains of the blend in a direction of the at least one or more sections greater than an amount of alignment of the polymer chains of the blend in a direction of another of the at least one or more sections.
摘要翻译：生物相容性材料可以被配置成任何数量的可植入医疗装置，包括腔内支架。可以使用聚合物材料来制造这些装置中的任何装置，包括支架。支架可以是气囊可扩张的或自扩张的。聚合物材料可以包括添加剂如药物或其他生物活性剂以及不透射线的试剂。通过聚合物的优先机械变形，聚合物链可以被定向以实现某些期望的性能特征。在一个实施方案中，可植入医疗装置包括框架结构，所述框架结构包括至少一个元件，所述至少一个元件具有由至少一种聚合物和至少一种增塑剂共混形成的具有增加的韧性的可变形框架结构的一个或多个部分，以及其中所述一个或多个部分中的至少一个在所述至少一个或多个部分的方向上具有所述共混物的聚合物链的排列量大于所述共混物的聚合物链在排列方向上的排列量至少一个或多个部分中的另一个。

9. 发明授权

EP1440701B1 Method of coating medical devices 失效转让
标题翻译：一种用于涂覆医疗器械的过程
公开(公告)号：EP1440701B1
公开(公告)日：2006-07-05
申请号：EP04250322.7
申请日：2004-01-22
申请人： Cordis Corporation
发明人： Narayanan, Pallassana V.
IPC分类号： A61L31/12 , A61L31/16
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/416 , A61L2300/606 , C08L27/16 , C08L27/20

10. 发明公开

EP1872808A1 Polymeric stent having modified molecular structures in selected regions of the hoops and method for increasing elongation at break 审中-公开
标题翻译：聚合物支架具有修饰的分子结构中选择的区域和断裂伸长率增加的环方法
公开(公告)号：EP1872808A1
公开(公告)日：2008-01-02
申请号：EP07252135.4
申请日：2007-05-25
申请人： Cordis Corporation
发明人： Burgermeister, Robert , Contiliano, Joseph H. , Dave, Vipul , Li, Yufu , Narayanan, Pallassana V. , Overaker, David W. , Zhang, Qiang
IPC分类号： A61L31/04 , B29C55/06 , B29C55/14 , C08J3/00 , A61F2/90
CPC分类号： B29C55/065 , A61F2/91 , A61L31/04 , A61L31/14 , B29C55/14 , B29C55/26 , B29K2995/0056 , B29L2031/753
摘要： A biocompatible material maybe configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. By preferential mechanical deformation of the polymer, the polymer chains may be oriented to achieve certain desirable performance characteristics.
摘要翻译：生物相容性材料可以被配置成任何数量包括管腔内的支架植入医疗装置。聚合材料可以被用于制造任何合成设备，包括支架。支架可以是球囊扩张或自扩张。通过聚合物的优惠机械变形时，聚合物链可被定向为获得某些所需的性能特性。

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