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1. 发明授权

US06770101B2 Prostatic stent and delivery system 失效
标题翻译：前列腺支架和输送系统
公开(公告)号：US06770101B2
公开(公告)日：2004-08-03
申请号：US09973562
申请日：2001-10-09
申请人： Joseph P. Desmond, III , James A. Teague
发明人： Joseph P. Desmond, III , James A. Teague
IPC分类号： A61F236
CPC分类号： A61F2/94 , A61F2/04 , A61F2/95 , A61F2002/047 , A61F2220/005 , A61F2220/0058 , A61F2230/0078 , A61F2250/0039
摘要： A collapsible and expandable stent includes a body segment, first and second terminal ends spaced apart from each other, a substantially smooth wall and a lumen extending between the first and second ends. The device can be used for maintaining the patency of the prostatic urethra in a male patient. The stent may be designed according to the individual needs of particular patients. A delivery system for deploying the stent and other collapsible and expandable stents in the body of the patient comprises a retractable sheath, a shaft and a locking element to reversibly lock the sheath to the shaft.
摘要翻译：可折叠和可扩展的支架包括主体段，彼此间隔开的第一和第二终端，基本平滑的壁和在第一和第二端之间延伸的内腔。该装置可用于在男性患者中维持前列腺尿道的通畅。可以根据特定患者的个体需要设计支架。用于将支架和其他可折叠和可扩展的支架部署在患者体内的递送系统包括可伸缩护套，轴和锁定元件，以将护套可逆地锁定到轴。

2. 发明授权

US06758865B1 Soft tissue xenografts 失效
标题翻译：软组织异种移植
公开(公告)号：US06758865B1
公开(公告)日：2004-07-06
申请号：US09623729
申请日：2001-02-26
申请人： Kevin R. Stone , Uri Galili
发明人： Kevin R. Stone , Uri Galili
IPC分类号： A61F236
CPC分类号： A61L27/3687 , A61F2/08 , A61L27/3604 , A61L27/3683 , Y10S623/915
摘要： A method for preparing a soft tissue xenograft includes the steps of removing at least a portion of a soft tissue from a non-human animal to provide a xenograft; washing the xenograft in saline and alcohol; subjecting the xenograft to cellular disruption treatment; and either digesting the xenograft with a glycosidase or glycosidase digestion followed by treatment for sialylation. A soft tissue xenograft for implantation into a human includes a portion of a soft tissue from a non-human animal, wherein the portion has extracellular matrix and substantially only dead cells. The matrix and dead cells have substantially no surface &agr;-galactosyl moieties and have sialic acid molecules linked to at least a portion of surface carbohydrate moieties. Each of the xenografts of the invention has substantially the same mechanical properties as a corresponding native soft tissue.
摘要翻译：一种制备软组织异种移植物的方法包括从非人动物中去除软组织的至少一部分以提供异种移植物的步骤; 用盐水和酒精清洗异种移植物; 使异种移植物进行细胞破坏处理; 并用糖苷酶或糖苷酶消化消化异种移植物，然后进行唾液酸化处理。用于植入人的软组织异种移植物包括来自非人动物的软组织的一部分，其中所述部分具有细胞外基质并且基本上仅仅是死细胞。基质和死细胞基本上没有表面α-半乳糖基部分，并且唾液酸分子与至少一部分表面碳水化合物部分连接。本发明的每个异种移植物具有与相应的天然软组织基本相同的机械性质。

3. 发明授权

US06755869B2 Intragastric prosthesis for the treatment of morbid obesity 有权
公开(公告)号：US06755869B2
公开(公告)日：2004-06-29
申请号：US10057469
申请日：2002-01-25
申请人： Kurt Geitz
发明人： Kurt Geitz
IPC分类号： A61F236
CPC分类号： A61F5/0036 , A61B17/0469 , A61B2017/00004 , A61B2017/00867 , A61F2/0036
摘要： A porous weave of bioabsorbable filaments having an open mesh configuration is formed into an oblate shape having dimensions greater than the esophageal opening and gastric outlet of a stomach. The resulting prosthesis is deployed in the stomach and is of a size to be retained in the proximate portion thereof for exerting pressure on the upper fundus. The prosthesis limits the amount of food that may be held within the stomach, and exerts pressure on the fundus to create a sensation of being full, resulting in weight loss.

4. 发明授权

US06740121B2 Intragastric stent for duodenum bypass 有权
公开(公告)号：US06740121B2
公开(公告)日：2004-05-25
申请号：US10057434
申请日：2002-01-25
申请人： Kurt Geitz
发明人： Kurt Geitz
IPC分类号： A61F236
CPC分类号： A61F5/0076 , A61F2/04 , A61F2002/044 , A61F2210/0004
摘要： A porous weave of bioabsorbable filaments is encased in an elastic membrane to form a thin-walled stent. The stent is sized to be snugly fitted in the proximate portion of the duodenum of a patient, to induce weight loss by limiting uptake of food passing through the stent. After a predetermined period, the stent degrades and passes from the body without surgical intervention.

5. 发明授权

US06699293B2 Prosthesis having wedge-shaped body 失效
标题翻译：具有楔形体的假体
公开(公告)号：US06699293B2
公开(公告)日：2004-03-02
申请号：US10164764
申请日：2002-06-07
申请人： Patrick Michel White
发明人： Patrick Michel White
IPC分类号： A61F236
CPC分类号： A61F2/36 , A61F2/30734 , A61F2/367 , A61F2/40 , A61F2002/30112 , A61F2002/30156 , A61F2002/30158 , A61F2002/30332 , A61F2002/30342 , A61F2002/30354 , A61F2002/30474 , A61F2002/30484 , A61F2002/30574 , A61F2002/30596 , A61F2002/30598 , A61F2002/30604 , A61F2002/30738 , A61F2002/3674 , A61F2002/4018 , A61F2002/4051 , A61F2002/4062 , A61F2002/4074 , A61F2220/0025 , A61F2220/0033 , A61F2230/0004 , A61F2230/0023 , A61F2230/0026
摘要： A modular orthopedic prosthesis has a body with a generally triangular cross-section near one end, allowing its angular corners to bite or incise into the surrounding bone cavity for rotational stability. A stem, which may be either unitary or modular in structure, is received within a through-bore of the body, having a proximal neck and distal shaft. A connecting sleeve receives the stem and is, in turn, received within the bore of the body, then actuated to lock the stem and body together.
摘要翻译：模块化矫形假体具有在一端附近具有大致三角形横截面的主体，允许其角角部咬入或切入周围的骨腔以获得旋转稳定性。杆体可以是整体的或模块化的结构，其容纳在主体的通孔内，具有近端颈部和远端轴。连接套筒容纳杆，并且又接纳在主体的孔内，然后被致动以将杆和身体锁定在一起。

6. 发明授权

US06626950B2 Composite scaffold with post anchor for the repair and regeneration of tissue 有权
标题翻译：复合支架用锚固修复和再生组织
公开(公告)号：US06626950B2
公开(公告)日：2003-09-30
申请号：US09893813
申请日：2001-06-28
申请人： Kelly R. Brown , Mark C. Zimmerman , Yufu Li
发明人： Kelly R. Brown , Mark C. Zimmerman , Yufu Li
IPC分类号： A61F236
CPC分类号： A61L27/56 , A61B17/00491 , A61B2017/00004 , A61B2017/0646 , A61F2/08 , A61F2/28 , A61F2/30749 , A61F2/30756 , A61F2/30965 , A61F2/3872 , A61F2/442 , A61F2002/2817 , A61F2002/30011 , A61F2002/30028 , A61F2002/30032 , A61F2002/30062 , A61F2002/30069 , A61F2002/30233 , A61F2002/30563 , A61F2002/30677 , A61F2002/30751 , A61F2002/30762 , A61F2002/30766 , A61F2002/30878 , A61F2002/30879 , A61F2002/30904 , A61F2002/30957 , A61F2002/30971 , A61F2002/4631 , A61F2210/0004 , A61F2230/0069 , A61F2250/0023 , A61F2250/003 , A61F2250/0051 , A61F2310/00179 , A61F2310/00221 , A61F2310/00293 , A61F2310/00365 , A61F2310/0097 , A61L27/425 , A61L27/46 , B29C44/1214
摘要： A prosthetic implant having a tissue scaffold and a fixation device with a scaffold support and an anchoring post. The anchoring post extends from a surface of the scaffold support at a selected angle with the scaffold support embedded within the scaffold. The scaffold has a porous ceramic phase and a porous polymer phase. The polymer is foamed while in solution that is infused in the pores of the ceramic to create a interphase junction of interlocked porous materials and embedding the scaffold support portion of the fixation device. The preferred method for foaming is by lyophilization. The scaffold may be infused or coated with a variety of bioactive materials to induce ingrowth or to release a medicament. The mutilayered porous scaffold can mimic the morphology of an injured tissue junction with a gradient morphology and cell composition.
摘要翻译：具有组织支架和具有脚手架支撑件和锚固柱的固定装置的假体植入物。锚固支架从脚手架支撑件的表面以选定的角度延伸，脚手架支架嵌入在支架内。支架具有多孔陶瓷相和多孔聚合物相。聚合物在溶于陶瓷孔中的溶液中发泡，以产生互锁多孔材料的相间接合并嵌入固定装置的支架支撑部分。优选的发泡方法是通过冻干。可以将支架注入或涂覆各种生物活性材料以诱导向内生长或释放药物。多层多孔支架可以模拟具有梯度形态和细胞组成的损伤组织结的形态。

7. 发明授权

US06616697B2 Hip implant assembly 失效
公开(公告)号：US06616697B2
公开(公告)日：2003-09-09
申请号：US09805323
申请日：2001-03-13
申请人： Nicholas G. Sotereanos
发明人： Nicholas G. Sotereanos
IPC分类号： A61F236
CPC分类号： A61B17/175 , A61B17/1721 , A61B17/1725 , A61B17/1753 , A61B17/744 , A61B17/86 , A61F2/30767 , A61F2/3601 , A61F2002/30011 , A61F2002/30113 , A61F2002/30156 , A61F2002/30171 , A61F2002/3021 , A61F2002/30217 , A61F2002/30324 , A61F2002/30332 , A61F2002/30354 , A61F2002/30474 , A61F2002/30507 , A61F2002/30604 , A61F2002/30616 , A61F2002/30706 , A61F2002/30769 , A61F2002/30774 , A61F2002/30782 , A61F2002/30785 , A61F2002/30787 , A61F2002/30827 , A61F2002/30878 , A61F2002/30879 , A61F2002/30891 , A61F2002/30906 , A61F2002/30929 , A61F2002/30968 , A61F2002/3611 , A61F2002/3625 , A61F2002/3631 , A61F2002/365 , A61F2002/3652 , A61F2002/366 , A61F2002/3684 , A61F2002/4636 , A61F2002/4667 , A61F2220/0025 , A61F2220/0033 , A61F2230/0006 , A61F2230/0023 , A61F2230/005 , A61F2230/0067 , A61F2250/0023 , A61F2250/0036 , A61F2250/0082 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00407 , A61F2310/00413 , A61F2310/00796
摘要： An implant and method for replacement of the proximal portion of a femur, and specifically for replacement of the natural femoral head is provided. The implant includes a body member for insertion, in use, through the natural femoral neck and in substantial alignment therewith; a head member with a spherical portion for engagement with a natural or a prosthetic hip socket; a joining portion for joining the head member to the body member; and a rod for insertion, in use, through the transverse passage of the body member. The rod is designed such that it has a cross-sectional configuration that contacts the cortical surfaces in the bone and inhibits micro-motion within the bone. In addition, the transverse passage of the body member is configured to complement the configuration of the rod such that the need for stabilizing screws toward the distal end of the rod is eliminated when the implant is assembled within the patient.

8. 发明授权

US06540788B1 Leaf-shaped shaft of a hip joint prosthesis for anchoring in the femur 有权
标题翻译：用于锚固在股骨中的髋关节假体的叶形轴
公开(公告)号：US06540788B1
公开(公告)日：2003-04-01
申请号：US09548166
申请日：2000-04-13
申请人： Karl Zweymüller
发明人： Karl Zweymüller
IPC分类号： A61F236
CPC分类号： A61F2/3662 , A61F2002/30535 , A61F2250/0058
摘要： Leaflike shaft (1) of a hip-joint prosthesis for anchoring in the femur, according to a towards a distal end (5) [sic], with a femur-anchoring section (1a, . . . 1i) having a long axis (A) and with a prosthesis neck (2), wherein the femur-anchoring section 1a, . . . 1i) has a substantially rectangular external contour in a plane perpendicular to the long axis (A), optionally with recesses in the side edges and/or at the corners.
摘要翻译：根据朝向远端（5）的方式锚固在股骨中的髋关节假体的叶状轴（1），具有具有长轴线的股骨锚固部分（1a，...，1i） A）和假体颈部（2），其中股骨锚固部分1a，。。 1i）在垂直于长轴线（A）的平面中具有基本上矩形的外部轮廓，可选地具有侧边缘和/或拐角处的凹部。

9. 发明授权

US06508841B2 Method and apparatus for segmental bone replacement 失效
标题翻译：节段性骨置换的方法和装置
公开(公告)号：US06508841B2
公开(公告)日：2003-01-21
申请号：US09776584
申请日：2001-02-02
申请人： Daniel L. Martin , John Robert White
发明人： Daniel L. Martin , John Robert White
IPC分类号： A61F236
CPC分类号： A61B17/1725 , A61B17/164 , A61B17/1668 , A61B17/1717 , A61B17/72 , A61B17/7233 , A61B2017/1602 , A61F2/28 , A61F2/3601 , A61F2/3607 , A61F2002/30535 , A61F2250/0058
摘要： A bone attachment assembly for a remaining portion of a long bone diaphysis following resection is provided. The assembly includes a main body, means for anchoring the device with respect to the remaining bone portion, such as an anchor body, and means for attaching the main body to the means for anchoring. The means for attaching the main body may preferably be in the form of one or more washer springs retained upon a connecting rod attached to the means for anchoring. The assembly may be connected to an orthopedic appliance, an interposed orthopedic appliance connected to a second bone attachment assembly, or a transcutaneous bar for attaching an external appliance. A reaming device for creating an intramedullary cavity, a guide device for guiding an aperture-forming procedure in a remaining bone portion, and a milling device for shaping an interface surface of the bone in a preselected geometry are also provided. In the method of the present invention, a cavity is created within a remaining bone portion using the reaming device. At least one aperture is created using the guide device, and the bone surface is milled to a preselected geometry using the milling device. The above components are then assembled together within the cavity to form the device of the present invention. The device may then be connected to other devices as stated above. A bone attachment assembly may also be provided having a compliant section integrally disposed that is operable for being converted to a preselected condition of expansion prior to or following implantation.
摘要翻译：提供了一种用于切除后的长骨骨干的剩余部分的骨附着组件。组件包括主体，用于将装置相对于剩余的骨部分固定的装置，例如锚固体，以及用于将主体附接到固定装置的装置。用于安装主体的装置可以优选地为保持在连接到用于锚定的装置的连接杆上的一个或多个垫圈弹簧的形式。组件可以连接到矫形器具，连接到第二骨附着组件的插入的矫形器具或用于附接外部器具的经皮条。还提供了一种用于创建髓内腔的扩孔装置，用于在剩余的骨部分中引导孔径成形过程的引导装置，以及用于使预定几何形状的骨的界面形成的研磨装置。在本发明的方法中，使用所述扩孔装置在剩余的骨部内产生空腔。使用引导装置产生至少一个孔，并且使用铣削装置将骨表面铣削成预先选定的几何形状。然后将上述组分在空腔内组装在一起以形成本发明的装置。然后可以将设备连接到如上所述的其他设备。还可以提供骨附件组件，其具有整体设置的柔性部分，其可操作以在植入之前或之后转换为预选的膨胀状态。

10. 发明授权

US06506217B1 Moldable post-implantation bone filler and method 有权
标题翻译：可塑植入后骨填料及方法
公开(公告)号：US06506217B1
公开(公告)日：2003-01-14
申请号：US09537281
申请日：2000-03-28
申请人： G. William Arnett
发明人： G. William Arnett
IPC分类号： A61F236
CPC分类号： A61L27/24 , A61F2/28 , A61F2002/30957 , A61F2310/00293 , A61F2310/00341 , A61F2310/00359 , A61F2310/00365 , A61L27/12 , A61L2430/02
摘要： Methods for correcting defects at bone repair sites are provided, which use a moldable, post-implantable bone conforming material. The method includes the steps of preparing a bone conforming material, shaping the moldable paste, curing the paste to form a hardened implant, disposing the implant at a repair site, allowing tissue to overlay the repair site during healing and if necessary, further molding the implant to the desired contours of the bony structure being repaired for up to eight weeks after the surgery by applying pressure to the tissue overlaying the implant.
摘要翻译：提供了用于矫正骨修复部位缺陷的方法，其使用可模制的，可植入后的骨骼符合材料。该方法包括以下步骤：制备骨骼符合材料，成形可模制糊料，固化糊料以形成硬化植入物，将植入物置于修复部位，允许组织在愈合过程中覆盖修复部位，如有必要，进一步模制通过对覆盖植入物的组织施加压力，将手术后修复骨髓结构的期望轮廓长达八周。

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