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1. 发明申请

WO2023002326A2 CATHETER HAVING COMPLIANT BALLOON 审中-公开
公开(公告)号：WO2023002326A2
公开(公告)日：2023-01-26
申请号：PCT/IB2022/056561
申请日：2022-07-16
申请人： OTSUKA MEDICAL DEVICES CO., LTD.
发明人： MAZZONE, James , DAILEY, Eric , DONOVAN, Ryan R. , MERINO, Jaime , THIRUMALAI, Shruthi
IPC分类号： A61N7/02 , A61B2017/22068 , A61B2018/00023 , A61B2018/00285 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00744 , A61M2025/1068 , A61M2205/0216 , A61M25/1002 , A61N2007/0026 , A61N2007/003 , A61N2007/0043 , A61N7/022
摘要： A catheter (102), comprising: a catheter shaft (212) having a fluid channel (420), an ultrasound transducer (214) and a compliant balloon (108) mounted on the catheter shaft (212) and having an interior (504) in fluid communication with the fluid channel (420) and containing the ultrasound transducer (214). The compliant balloon (108) includes a balloon wall (502) having a working section (1600) radially surrounding the ultrasound transducer (214), a proximal shoulder (510B) proximal to the working section (1600), and a distal shoulder (510A) distal to the working section (1600). The balloon wall (502) is thicker at the proximal shoulder (510B) and the distal shoulder (510A) than at the working section (1600).

2. 发明申请

WO2022258124A2 ENERGY-BASED VESSEL SEALING DEVICE FOR SKIN-SPARING MASTECTOMY AND ENDOSCOPIC MASTECTOMY 审中-公开
公开(公告)号：WO2022258124A2
公开(公告)日：2022-12-15
申请号：PCT/EG2021/000015
申请日：2021-06-08
申请人： EL ERIAN, ALaa, Mohammad
发明人： EL ERIAN, ALaa, Mohammad
IPC分类号： A61B90/00 , A61B18/1445 , A61B2017/00353 , A61B2017/320056 , A61B2018/00404 , A61B2018/00607 , A61B2018/0063 , A61B2018/00642 , A61B2018/00708 , A61B2018/00875 , A61B2018/00994
摘要： The old adage "Necessity is the mother of invention" holds true but it is in the mind of the beholder. SSM including NSM is a challenging, technically demanding and time consuming procedure. It represents a challenge to the surgeon in regard to the ability to perform a complete and through glandular mastectomy enbloc with axillary nodal dissection from within the narrow, small confines of the periareolar hole. An ideal SSM procedure produces a uniform thickness skin flap with no much inclusion of mammary tissue within, while simultaneously not risking flap viability. Energy-based device technology is a marvelous recent addition to the armamentarium of open and endoscopic surgery that has greatly facilitated hemostatic tissue dissection and vessel sealing. So it was plausible to think of an Energy-Based Device specified for SSM procedure to make it an easy fast task with enhanced ergonomicity. The new invented EVSD has a long curved half-cylinder shaped jaws that on closure form a Hegar`s dilator like cylindrical rod with a blunt tipped conical end. On creating skin flaps of SSM, such unique jaw configuration that works as a Hegar`s dilator allows for the formation of long juxta-tunnels through the subcutaneous fat space along the plane of the SL of SF, then grasping tissue bridges and blood vessels between the created adjacent tunnels. The combined retractable monopolar L-hook is used in an alternate way with the Hegar`s dilator shaped jaw for incision and dissection of pectoral fascia, interpectoral fascia, clavi-pectoral fascia, and subscapular fascia with sweeping off the axillary contents in bloc, so the whole procedure of SSM is done with an only one device in a quick and more ergonomic manner, obviating the need for instrument exchange and very much applications needed when using other conventional energy based devices with small unsuitable jaw configuration, in addition to fulfilling the orthodox aesthetic and oncologic safety standards.

3. 发明申请

WO2022218922A2 CHEMICAL ABLATION THERAPY DELIVERY SYSTEM 审中-公开
公开(公告)号：WO2022218922A2
公开(公告)日：2022-10-20
申请号：PCT/EP2022/059626
申请日：2022-04-11
申请人： MEDTRONIC IRELAND MANUFACTURING UNLIMITED COMPANY
发明人： SINGH, Manoj Kumar
IPC分类号： A61M25/00 , A61M25/10 , A61B18/00 , A61B2018/00214 , A61B2018/0022 , A61B2018/00255 , A61B2018/00267 , A61B2018/00273 , A61B2018/00279 , A61B2018/00285 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/143 , A61M2025/0087 , A61M2025/0096 , A61M25/0084 , A61M25/104
摘要： Various embodiments chemical ablation therapy delivery systems are disclosed herein. One aspect of such a system utilizes an expandable element, at least one guide tube that is fixed, secured, or otherwise anchored to the expandable element, and a needle that is movably disposed within the guide tube. Another aspect of such a system utilizes an expandable element, at least one fluid delivery tube or ablation conduit that is fixed, secured, or otherwise anchored to the expandable element, and at least one injector that extends from an outer perimeter of the corresponding fluid delivery tube, is fluidly interconnected with the corresponding fluid delivery tube, and protrudes beyond an outer perimeter of the expandable element at least when in its deployed state or configuration. Yet another aspect of such a system includes an inflatable tube, where at least one injector is separately attached to the inflatable tube and is fluidly connected with an interior space of the inflatable tube.

4. 发明申请

WO2022207856A1 EXOTHERMIC REACTION-BASED ABLATION 审中-公开
公开(公告)号：WO2022207856A1
公开(公告)日：2022-10-06
申请号：PCT/EP2022/058684
申请日：2022-03-31
申请人： MEDTRONIC IRELAND MANUFACTURING UNLIMITED COMPANY
发明人： SINGH, Manoj Kumar
IPC分类号： A61B18/06 , A61B18/14 , A61B18/00 , A61K9/00 , A61F2/82 , A61B18/1482 , A61B18/1492 , A61B2018/00107 , A61B2018/00154 , A61B2018/0022 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61F2/07 , A61F2/90 , A61F2250/0031 , A61F2250/0067 , A61K9/0024
摘要： Various embodiments of ablation elements are disclosed herein, where the ablation element includes a biodegradable shell. Calcium chloride is retained within the biodegradable shell. When the ablation element is delivered to a target location within the body of a patent, the biodegradable shell degrades to release the calcium chloride. A reaction between the released calcium chloride and bodily fluids will generate heat, which in turn will ablate biological material in proximity to the reactive region.

5. 发明申请

WO2022028826A1 ELECTROSURGICAL APPARATUS FOR CUTTING AND COAGULATION 审中-公开
公开(公告)号：WO2022028826A1
公开(公告)日：2022-02-10
申请号：PCT/EP2021/069513
申请日：2021-07-13
申请人： CREO MEDICAL LIMITED
发明人： HANCOCK, Christopher Paul , WHITE, Malcolm
IPC分类号： A61B18/18 , A61B18/12 , A61B18/14 , A61B18/1492 , A61B18/1815 , A61B2017/00141 , A61B2017/00154 , A61B2018/00404 , A61B2018/00589 , A61B2018/00601 , A61B2018/00607 , A61B2018/00702 , A61B2018/00767 , A61B2018/00785 , A61B2018/00827 , A61B2018/00869 , A61B2018/00892 , A61B2018/00994 , A61B2018/122 , A61B2018/126 , A61B2018/1861
摘要： The invention relates to an electrosurgical apparatus for cutting and coagulating biological tissue. In particular, the present invention provides an electrosurgical generator arranged to generate radiofrequency (RF) electromagnetic (EM) energy and microwave frequency EM energy; wherein the electrosurgical generator is operable in each of a coagulation mode and a cutting mode, wherein in the coagulation mode the electrosurgical generator is arranged to deliver the RF EM energy and the microwave EM energy simultaneously in a coagulation composite waveform comprising a dominant microwave signal and a supplementary RF signal, and wherein in the cutting mode the electrosurgical generator is arranged to deliver the RF EM energy and the microwave EM energy simultaneously in a cutting composite waveform comprising a dominant RF signal and a supplementary microwave signal.

6. 发明申请

WO2022269545A2 SYSTEMS FOR APPLYING ENERGY TO DENERVATE A PULMONARY ARTERY 审中-公开
公开(公告)号：WO2022269545A2
公开(公告)日：2022-12-29
申请号：PCT/IB2022/055854
申请日：2022-06-23
申请人： GRADIENT DENERVATION TECHNOLOGIES SAS
发明人： AMAOUA, David , GRASSE, Martin , MISCHO, Chiara , CANNON, William , MAXWELL, Adam Douglas
IPC分类号： A61B18/14 , A61N7/02 , A61N7/00 , A61B90/00 , A61B18/00 , A61B18/1492 , A61B2018/00196 , A61B2018/0022 , A61B2018/00279 , A61B2018/00351 , A61B2018/00375 , A61B2018/00404 , A61B2018/00434 , A61B2018/00577 , A61B2018/00732 , A61B2018/00738 , A61B2018/00779 , A61B2018/00785 , A61B2018/00791 , A61B2018/00821 , A61B2018/00875 , A61B2018/00916 , A61B2018/00994 , A61B2090/061 , A61B2090/0811 , A61B2090/3937 , A61B90/08 , A61B90/39 , A61N2007/003 , A61N2007/0043 , A61N7/022
摘要： A catheter system for ablation of tissue around a blood vessel, e.g., the pulmonary artery, to reduce neural activity of nerves surrounding the blood vessel. The catheter system includes an elongate shaft having a proximal portion coupled to a handle, and a distal portion. The distal portion includes a transducer and an expandable anchor, which may be actuated to transition between a collapsed delivery state and an expanded deployed state where the anchor centralizes the transducer within the blood vessel. The transducer may be actuated to emit energy to reduce neural activity of the nerves surrounding the blood vessel. Systems and method are further provided for confirming that neural activity of the nerves surround the blood vessel has been sufficiently reduced.

7. 发明申请

WO2022125375A2 SURGICAL INSTRUMENTS, SYSTEMS, AND METHODS INCORPORATING ULTRASONIC AND ELECTROSURGICAL FUNCTIONALITY 审中-公开
公开(公告)号：WO2022125375A2
公开(公告)日：2022-06-16
申请号：PCT/US2021/061631
申请日：2021-12-02
申请人： COVIDIEN LP
发明人： LYONS, Michael B. , DUNNING, James E. , BRADLEY, Kristen P. , VAN TOL, David J. , TSCHUDY, Christopher T. , MALANG, Keith W. , TONN, Donald L. , JOHNSTON, Mark A. , FAGAN, James R.
IPC分类号： A61B18/14 , A61B17/32 , A61B34/30 , A61B17/320092 , A61B18/1445 , A61B2017/00026 , A61B2018/00404 , A61B2018/00601 , A61B2018/0063 , A61B2018/00678 , A61B2018/00875 , A61B2018/1253 , A61B2018/126 , A61B2018/1412 , A61B2018/1452
摘要： A method of treating tissue includes clamping tissue between an ultrasonic blade and a jaw member and simultaneously: transmitting ultrasonic energy to the ultrasonic blade to vibrate the ultrasonic blade at a first blade velocity thereby heating the clamped tissue; and supplying electrosurgical energy, at a constant voltage, to the jaw member and the ultrasonic blade at different potentials such that the electrosurgical energy is conducted therebetween and through the clamped tissue to heat the clamped tissue. An impedance of the clamped tissue is monitored and the simultaneous transmission of ultrasonic energy and supply of electrosurgical energy is terminated and/or a notification is output once the clamped tissue is sealed, as indicated by the impedance of the clamped tissue being equal to or greater than a threshold impedance. Surgical instruments and end effectors thereof for treating tissue in this manner are also provided.

8. 发明申请

WO2021255013A1 ATHERECTOMY GUIDANCE THROUGH PHOTOACOUSTIC SIGNAL ANALYSIS 审中-公开
公开(公告)号：WO2021255013A1
公开(公告)日：2021-12-23
申请号：PCT/EP2021/066081
申请日：2021-06-15
申请人： KONINKLIJKE PHILIPS N.V.
发明人： ERKAMP, Ramon, Quido , CHEN, Alvin , BHARAT, Shyam , ZHENG, Mingxin , TOPOREK, Grzegorz, Andrzej , CEZO, James, David
IPC分类号： A61B5/00 , A61B18/24 , A61B18/245 , A61B2018/00404 , A61B2018/00577 , A61B2018/00642 , A61B2018/00785 , A61B2018/00898 , A61B2018/00904 , A61B5/0095 , A61B5/6876
摘要： Methods, Apparatuses, and Systems of operating a laser atherectomy system to perform an endoscopic atherectomy procedure within a vessel at a therapeutic region of an anatomical condition by use of an atherectomy laser device coupled to an ultrasound imaging probe. The atherectomy laser device operates to generate photoacoustic signals from a light source of the atherectomy laser device to for guidance within the vessel and to characterize tissue about the therapeutic region by delivery of pulsed wavelengths within the vessel, and to perform operations of tissue ablation directed to the anatomical condition. This enables guidance of the atherectomy laser device by feedback from the viewing of photoacoustic images based on photoacoustic signals generated the atherectomy laser device and created in response to changes in acoustic intensity due to changes of optical wavelength monitored by the ultrasound imaging probe.

9. 发明申请

WO2021186449A2 TREATMENT OF INTERNAL SPACES USING PLASMA GENERATING DEVICE 审中-公开
公开(公告)号：WO2021186449A2
公开(公告)日：2021-09-23
申请号：PCT/IL2021/050303
申请日：2021-03-18
申请人： CAPS MEDICAL LTD.
发明人： UCHITEL, Ilan Oleg , KOGAN, Boris
IPC分类号： A61B18/04 , A61B34/20 , A61B18/00 , A61B18/042 , A61B2018/00196 , A61B2018/00261 , A61B2018/00285 , A61B2018/00351 , A61B2018/00404 , A61B2018/00494 , A61B2018/005 , A61B2018/00517 , A61B2018/00541 , A61B2218/007
摘要： Plasma delivery tips of medical-grade plasma generating devices are configured to exclude potential contaminants while operating within body cavities. In some embodiments, delivery tips are provided with an antechamber, which is optionally filled by pressure of ionizing gas to prevent contamination. Some embodiments are provided with one or more interior and/or exterior valves configured to prevent proximal ingress of contamination to the longitudinal position of the discharge electrode, or at all into the gas delivery lumen. In some embodiments, an expandable distal section of the plasma delivery tip acts as a valve which seals when closed, and when open expands to generate an inflated antechamber into which plasma is delivered.

10. 发明申请

WO2021122940A1 MEDIZINISCHES INSTRUMENT 审中-公开
公开(公告)号：WO2021122940A1
公开(公告)日：2021-06-24
申请号：PCT/EP2020/086698
申请日：2020-12-17
申请人： AESCULAP AG
发明人： WALBERG, Erik , HEIZMANN, Patrick
IPC分类号： A61B17/29 , A61B17/295 , A61B18/14 , A61B18/1445 , A61B2017/00738 , A61B2017/2926 , A61B2018/00107 , A61B2018/00404 , A61B2018/0063 , A61B2018/1455 , A61B2090/034
摘要： Um ein medizinisches Instrument mit einem distalen und einem proximalen Ende, wobei am distalen Ende ein erstes Werkzeugelement und ein zweites Werkzeugelement relativ zueinander bewegbar angeordnet oder ausgebildet sind, wobei die Werkzeugelemente eine Werkzeugelementerstreckungsrichtung von proximal nach distal definieren, wobei das erste Werkzeugelement eine erste Werkzeugelementfläche und das zweite Werkzeugelement eine zweite Werkzeugelementfläche definieren, wobei die erste Werkzeugelementfläche und die zweite Werkzeugelementfläche aufeinander zu weisen, wobei die Werkzeugelemente im Bereich ihrer Werkzeugelementflächen eine Breite definieren, welche sich in einer Richtung quer, insbesondere senkrecht, zur Werkzeugelementerstreckungsrichtung und quer, insbesondere senkrecht, zu einer Flächennormalen der ersten Werkzeugelementfläche und/oder der zweiten Werkzeugelementfläche erstreckt, und wobei das erste Werkzeugelement und/oder das zweite Werkzeugelement mindestens ein Greifelement mit einer vom jeweiligen Werkzeugelement weg weisenden Greiffläche aufweist, so zu verbessern, dass eine Handhabung von Gewebe mit diesem insbesondere auch bei einem geradlinigen Verlauf der Werkzeugelementerstreckungsrichtung ermöglicht wird, wird vorgeschlagen, dass die Breite des Werkzeugelements ausgehend vom proximalen Ende des mindestens einen Werkzeugelements zum distalen Ende desselben hin abnimmt, dass die Breite mindestens ein lokales Minimum zwischen dem proximalen und dem distalen Ende aufweist und dass die Greiffläche im Bereich des lokalen Minimums der Breite ausgebildet ist.

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